Title: Book the Best Mission LUXURY Hotels - Upscale Hotels in Mission, TX | Expedia.ca [Hotels in Mission](https://expedia.ca/Mission-Hotels.d8743.Travel-Guide-Hotels)[Vacation Rentals in Mission](https://expedia.ca/Mission-Vacation-Rentals.d8743.Travel-Guide-VacationRentals)[Flights to Mission](https://expedia.ca/Cheap-Flights-To-Mission.d8743.Travel-Guide-Flights)[Mission Car Rentals](https://expedia.ca/Car-Rentals-In-Mission.d8743.Car-Rental-Guide)[Mission Vacation Packages](https://expedia.ca/Mission.d8743.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/976dbed18736fb254fd6c1809e26279f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Mission, TX ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mission Luxury Hotels Tonight [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=8743&startDate=2025-10-12&endDate=2025-10-13&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=8743&startDate=2025-10-13&endDate=2025-10-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=8743&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=8743&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mission Luxury Hotels ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2950000/2943100/2943096/42d7cb05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![King studio suite](https://images.trvl-media.com/lodging/3000000/2950000/2943100/2943096/4fd1ce30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/3000000/2950000/2943100/2943096/w656h504x16y8-959adda0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/3000000/2950000/2943100/2943096/1cbaa4ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Mission Mission 8.8/10 Excellent (1006) "Good spot for shopping " CA $105 CA $119 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/McAllen-Hotels-Hampton-Inn-And-Suites-Mission.h2943096.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=8743&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Mission Hotel Reviews ![Casa De Palmas, Trademark Collection by Wyndham](//images.trvl-media.com/lodging/1000000/10000/4200/4182/e7f1f019_y.jpg) ### Casa De Palmas, Trademark Collection by Wyndham 10/10 Excellent "A" [](https://expedia.ca/McAllen-Hotels-Casa-De-Palmas.h4182.Hotel-Information) ![Hampton Inn & Suites Mission](//images.trvl-media.com/lodging/3000000/2950000/2943100/2943096/42d7cb05_y.jpg) ### Hampton Inn & Suites Mission 10/10 Excellent "El chico de recepción muy amable " [](https://expedia.ca/McAllen-Hotels-Hampton-Inn-And-Suites-Mission.h2943096.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury holiday in Mission? > Use Expedia and let us help you arrange a flight to Miller Intl. Airport (MFE) airport or Reynosa, Tamaulipas (REX-General Lucio Blanco Intl.) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Mission has to offer. During your visit, you might want to enjoy the restaurants which Mission is known for. ### When can I expect good weather in Mission? > Planning for the weather is an important factor for making your trip to Mission a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 86°F, while the coldest months are January and December with an average of 65°F. Average annual precipitation for Mission is 22 inches. ### What's there to see and do in Mission? > When you're in Mission, enjoy exploring the sights and attractions here including Rio Grande, National Butterfly Center, and Anzalduas Park. 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