Title: Book the Best Mission District LUXURY Hotels - Upscale Hotels in Mission District, San Francisco | Expedia.ca

  

[Mission District Travel Guide](https://expedia.ca/San-Francisco-Mission-District.dx134035)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Mission District Car Rentals](https://expedia.ca/Car-Rentals-In-Mission-District.d134035.Car-Rental-Guide)[Mission District Vacations](https://expedia.ca/Mission-District.d134035.Destination-Travel-Guides)

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# Find Luxury Hotels in Mission District, San Francisco

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## Check availability on Mission District Luxury Hotels

Tonight

[Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2025-10-17&endDate=2025-10-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2025-10-18&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Top Mission District Luxury Hotels

![Lobby sitting area](https://images.trvl-media.com/lodging/7000000/6330000/6326400/6326351/373985d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laundry room](https://images.trvl-media.com/lodging/7000000/6330000/6326400/6326351/ad96a000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/7000000/6330000/6326400/6326351/cf6e8a24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/7000000/6330000/6326400/6326351/35b75ce5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### El Capitan Hotel

Mission District

4.6/10

(826)

"Mission district is amazing for food and nightlife. Stayed here because of that. Made a mistake roaches and bugs in the room. Crackheads in parking lot break on to your car (no security) "

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Doug

[](https://www.expedia.ca/San-Francisco-Hotels-El-Capitan-Hotel.h6326351.Hotel-Information)

![Outdoor spa tub](https://images.trvl-media.com/lodging/2000000/1150000/1145300/1145267/3ae7ddd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1150000/1145300/1145267/b2a17488.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1150000/1145300/1145267/19a23635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/2000000/1150000/1145300/1145267/17068cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Inn San Francisco

Mission District

9.6/10

Exceptional

(558)

"Amazing breakfast and staff is super helpful."

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephanie

CA $337

CA $393 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/San-Francisco-Hotels-Inn-San-Francisco.h1145267.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02&regionId=134035&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

## Top Mission District Hotel Reviews

![Hyatt Regency San Francisco](//images.trvl-media.com/lodging/1000000/30000/23800/23774/1f7903cc_y.jpg)

### Hyatt Regency San Francisco

10/10 Excellent

"Great location and views"

[](https://expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information)

![Crowne Plaza San Francisco Airport by IHG](//images.trvl-media.com/lodging/1000000/30000/28600/28502/336a0345_y.jpg)

### Crowne Plaza San Francisco Airport by IHG

10/10 Excellent

"Loved the amenities in my room. Lotion, hair products."

[](https://expedia.ca/San-Francisco-Hotels-Crowne-Plaza-San-Francisco-Airport.h28502.Hotel-Information)

![Bay Landing San Francisco Airport Hotel](//images.trvl-media.com/lodging/2000000/1120000/1110800/1110785/0c231d9b_y.jpg)

### Bay Landing San Francisco Airport Hotel

10/10 Excellent

"Very pleasant time"

[](https://expedia.ca/San-Francisco-Hotels-Bay-Landing-San-Francisco-Airport-Hotel.h1110785.Hotel-Information)

![The Pickwick Hotel](//images.trvl-media.com/lodging/1000000/20000/11800/11793/060ec935_y.jpg)

### The Pickwick Hotel

10/10 Excellent

"Clean room and comfortable bed"

[](https://expedia.ca/San-Francisco-Hotels-The-Pickwick-Hotel.h11793.Hotel-Information)

![Hilton San Francisco Financial District](//images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg)

### Hilton San Francisco Financial District

10/10 Excellent

" Very clean, friendly and professional staff. "

[](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information)

![Hyatt Centric Fisherman's Wharf San Francisco](//images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg)

### Hyatt Centric Fisherman's Wharf San Francisco

10/10 Excellent

"Excellent"

[](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information)

![DoubleTree by Hilton Hotel Berkeley Marina](//images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg)

### DoubleTree by Hilton Hotel Berkeley Marina

10/10 Excellent

"I love the clean, comfy beds and linens, the outdoor fireplace on the patio, the warm cookies, the tranquil atmosphere and the location on the water. The staff are friendly and supportive, offering smiles and warm choc chip cookies! I especially appreciated thier efforts to assist me when I needed to correct a date error in my reservation. All in all I love the hotel and always stay there when in the Bay Area. "

[](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information)

![Club Quarters Hotel in San Francisco](//images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg)

### Club Quarters Hotel in San Francisco

10/10 Excellent

"Great location clean room super nice staff ☺️"

[](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information)

![Comfort Inn by the Bay](//images.trvl-media.com/lodging/1000000/10000/6000/5984/d439a184_y.jpg)

### Comfort Inn by the Bay

10/10 Excellent

"Clean room, friendly staff, breakfast was a plus"

[](https://expedia.ca/San-Francisco-Hotels-Comfort-Inn-By-The-Bay.h5984.Hotel-Information)

## Frequently asked questions

### Are you searching for a great accommodation for your luxury trip to Mission District?

> Use Expedia to arrange your flight to San Francisco Intl. Airport (SFO) airport or Oakland Intl. Airport (OAK) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Mission District offers. During your visit, you might want to enjoy the bars which Mission District is known for.

### What's there to see and do in Mission District?

> Take in the sights and attractions that Mission District offers with a visit to San Francisco Public Library, Victoria Theatre, and SF Armory. If you have spare time during your trip, you might want to make a stop at Mission San Francisco de Asís and SOMA Pilipinas.

### How can I get around Mission District?

> It's easier to get around town comfortably when you know your options. Nearby metro stations include 16th Street Mission Station, 24th Street Mission Station, and Right Of Way/20th St Stop.

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-   [Ski Hotels in Noe Valley](https://www.expedia.ca/Noe-Valley-San-Francisco-Hotels-Ski-Hotel.0-n6155705-0-tSkiHotel.Travel-Guide-Filter-Hotels)
-   [Winery Hotels in Noe Valley](https://www.expedia.ca/Noe-Valley-San-Francisco-Hotels-Winery-Hotel.0-n6155705-0-tWineryHotel.Travel-Guide-Filter-Hotels)
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-   [Cheap Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Cheap-Hotels.0-0-d178305-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Hotels & Resorts for Couples in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Couples-Resorts-Hotels.0-0-d178305-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
-   [Green Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Green-Sustainable.0-0-d178305-tGreenSustainable.Travel-Guide-Filter-Hotels)
-   [Hotels with Wifi in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Hotel-With-Wifi.0-0-d178305-tHotelwithwifi.Travel-Guide-Filter-Hotels)
-   [Hotels with a Lazy River in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Hotels-With-A-Lazy-River.0-0-d178305-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels)
-   [Hotels with Childcare in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Hotels-With-Childcare.0-0-d178305-tHotelswithChildcare.Travel-Guide-Filter-Hotels)
-   [Hotels with Waterslides in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Hotels-With-Waterslides.0-0-d178305-tHotelswithWaterslides.Travel-Guide-Filter-Hotels)
-   [Lake Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Lake-Hotels.0-0-d178305-tLakeHotels.Travel-Guide-Filter-Hotels)
-   [Scuba Diving Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Scuba-Diving-Vacations.0-0-d178305-tscubadivingvacations.Travel-Guide-Filter-Hotels)
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-   [Waterpark Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Waterpark-Hotels.0-0-d178305-tWaterparkHotels.Travel-Guide-Filter-Hotels)
-   [Hotel Wedding Venues Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Wedding-Hotels.0-0-d178305-tWeddingHotels.Travel-Guide-Filter-Hotels)
-   [Beach Hotel Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Beach-Hotel.0-0-d506142-tBeachHotel.Travel-Guide-Filter-Hotels)
-   [Cheap Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Cheap-Hotels.0-0-d506142-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Hotels & Resorts for Couples in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Couples-Resorts-Hotels.0-0-d506142-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
-   [Family Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Family-Hotel.0-0-d506142-tFamilyHotel.Travel-Guide-Filter-Hotels)
-   [Historic Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Historic-Hotel.0-0-d506142-tHistoricHotel.Travel-Guide-Filter-Hotels)
-   [Hotels with a Pool in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Hotel-With-Pool.0-0-d506142-tHotelwithPool.Travel-Guide-Filter-Hotels)
-   [Lgbt Friendly Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-LGBT-Friendly-Hotel.0-0-d506142-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Luxury Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Luxury-Hotel.0-0-d506142-tLuxuryHotel.Travel-Guide-Filter-Hotels)
-   [Pet-Friendly Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Pet-Friendly-Hotel.0-0-d506142-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Ski Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Ski-Hotel.0-0-d506142-tSkiHotel.Travel-Guide-Filter-Hotels)
-   [Spa Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Spa-Hotel.0-0-d506142-tSpaHotel.Travel-Guide-Filter-Hotels)
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