Title: Hotels by La Quinta Inn & Suites in Mission District from CA $127 | Expedia.ca [Mission District Travel Guide](https://expedia.ca/San-Francisco-Mission-District.dx134035)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Mission District Car Rentals](https://expedia.ca/Car-Rentals-In-Mission-District.d134035.Car-Rental-Guide)[Mission District Vacations](https://expedia.ca/Mission-District.d134035.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476332-Mission-District-Sf.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in Mission District from CA $127 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 20 - Oct 21](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2025-10-20&endDate=2025-10-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 21 - Oct 22](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2025-10-21&endDate=2025-10-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mission District La Quinta Inn & Suites Hotels ![Garden](https://images.trvl-media.com/lodging/1000000/30000/27000/26945/a57ff5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/27000/26945/2e422e8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/30000/27000/26945/843b85cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/27000/26945/91034226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Francisco Airport West Millbrae 8.6/10 Excellent (1445) "Breakfast is good; room is clean, and the staff are amazing." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronald CA $179 CA $206 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-West.h26945.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/5d196618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/f426e9e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/4becccdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/3bdf7c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Francisco Airport N Downtown South San Francisco 8.0/10 Very good (2022) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gladys CA $142 CA $167 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/8000/7973/413632c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8000/7973/5b3126f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/8000/7973/10eb61a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8000/7973/ea44aae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Oakland - Hayward Hayward 8.4/10 Very good (1052) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Francisco CA $111 CA $127 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Oakland-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Oakland-Hayward.h7973.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04®ionId=134035&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMission-District-San-Francisco-Hotels-La-Quinta-Inn-Suites.0-n134035-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMission-District-San-Francisco-Hotels-La-Quinta-Inn-Suites.0-n134035-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Mission District Hotel Reviews ![Hyatt Regency San Francisco](//images.trvl-media.com/lodging/1000000/30000/23800/23774/1f7903cc_y.jpg) ### Hyatt Regency San Francisco 10/10 Excellent "Been to SF more than 10 times - usually stay around union square for Moscone - but honestly this is now my fav hotel, amazing design, very unique architecture. Rooms well maintained, clean and appointed and super friendly and helpful staff, nothing was a problem and everything I asked for sorted quickly and hassle free. This isnt always the case in SF. Bonus this part of town is without all the hassles and troubles you find further up in Union square and surrounds - the walk to Moscone wasnt bad and the hotel made it worth it. Definitely will be back here if I can. " [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information) ![Holiday Inn Golden Gateway by IHG](//images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "I enjoyed my stay — the hotel had a welcoming atmosphere and the amenities were nice. The room was spacious and the bed was comfortable. The only thing that stood out was that it wasn’t quite as clean as I expected (a bit of dust and a few missed spots). Other than that, it was a good experience, and I’d consider staying again." [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Hyatt Regency San Francisco Downtown SOMA ](//images.trvl-media.com/lodging/1000000/10000/500/491/5e565895_y.jpg) ### Hyatt Regency San Francisco Downtown SOMA 10/10 Excellent " Beautiful clean rooms helpful staff central located to just about anything great view on thirty six floor i could see golden gate from my room room and the water stunning great bartendars as well parking sucked 95 for the weekend did not move my car from parking garage because rates are insane but its frisco id stay here again" [](https://expedia.ca/San-Francisco-Hotels-The-Park-Central-San-Francisco-Hyatt-Affiliated-Hotel.h491.Hotel-Information) ![Club Quarters Hotel in San Francisco](//images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg) ### Club Quarters Hotel in San Francisco 10/10 Excellent "The water bottle refill station takes forever to fill up. Please see if 8th floor can have a faster water fill. Thank you. The front door wave wasn’t working, and the situation about the smoke smell in the room was handled right away, thank you, everything else was great. " [](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Handlery Union Square Hotel](//images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "Love stay at this property when visiting San Francisco. Francisco is extremely close to all tourist attractions in Union Square clean customer service will return." [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Best Western Plus Grosvenor Airport Hotel](//images.trvl-media.com/lodging/1000000/10000/7700/7635/062e9dfe_y.jpg) ### Best Western Plus Grosvenor Airport Hotel 10/10 Excellent "Yes" [](https://expedia.ca/San-Francisco-Hotels-Best-Western-Plus-Grosvenor-Airport-Hotel.h7635.Hotel-Information) ![Hyatt Centric Fisherman's Wharf San Francisco](//images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg) ### Hyatt Centric Fisherman's Wharf San Francisco 10/10 Excellent "Nice hotel, smart area, super clean room, great breakfast. " [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![Claremont Resort & Club](//images.trvl-media.com/lodging/1000000/10000/6700/6609/d997dca7_y.jpg) ### Claremont Resort & Club 10/10 Excellent "The staff was super accomodating. When I mentioned that street noise from my initial room was a bit annoying , they immediately offered me a room away from the street. They aim to please. " [](https://expedia.ca/Oakland-Hotels-Claremont-Club-Spa-A-Fairmont-Hotel.h6609.Hotel-Information) ![Chancellor Hotel on Union Square](//images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg) ### Chancellor Hotel on Union Square 10/10 Excellent "Great" [](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ## Find out more about Mission District ## Mission District Hotels Guide Expedia.ca offers a selection of 4782 hotels in Mission District. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Mission District. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Mission District neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Mission District, San Francisco now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Aparthotels in 16th Street Mission Station](https://www.expedia.ca/16th-Street-Mission-Station-Apart-Hotels.d6176452-aaApartHotels.Travel-Guide-Accommodation) - [Hotels near 16th Street Mission Station](https://www.expedia.ca/16th-Street-Mission-Station-Hotels.d6176452.Travel-Guide-Hotels) - [Villas in 16th Street Mission Station](https://www.expedia.ca/16th-Street-Mission-Station-Villas.d6176452-aaVillas.Travel-Guide-Accommodation) - [Historic Hotels in Bernal Heights](https://www.expedia.ca/Bernal-Heights-San-Francisco-Hotels-Historic-Hotel.0-n553248621561136356-0-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Bernal Heights](https://www.expedia.ca/Bernal-Heights-San-Francisco-Hotels-Luxury-Hotel.0-n553248621561136356-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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[Moxy Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-MOXY.0-0-d178305--bMOXY.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Marriott-Hotels-Resorts.0-0-d178305--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Melia Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Melia.0-0-d178305--bMelia.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Motel-6.0-0-d178305--bMotel6.Travel-Guide-Filter-Hotels) - [Rosewood Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Rosewood-Hotels.0-0-d178305--bRosewoodHotels.Travel-Guide-Filter-Hotels) - [San Francisco Hotels](https://www.expedia.ca/San-Francisco-Hotels.d178305.Travel-Guide-Hotels) - [Hotels near San Francisco Public Library](https://www.expedia.ca/San-Francisco-Public-Library-Hotels.0-l6155544-0.Travel-Guide-Filter-Hotels) - [Hotels near San Francisco Zen Center](https://www.expedia.ca/San-Francisco-Zen-Center-Hotels.0-l6155397-0.Travel-Guide-Filter-Hotels) - [Omni Hotels in South Beach](https://www.expedia.ca/South-Beach-San-Francisco-Hotels-Omni.0-n6203131-0--bOmni.Travel-Guide-Filter-Hotels) - [Kimpton Hotels in Tenderloin](https://www.expedia.ca/Tenderloin-San-Francisco-Hotels-Kimpton-Hotels.0-n6203136-0--bKimptonHotels.Travel-Guide-Filter-Hotels) - [Hotels near U.S. Mint](https://www.expedia.ca/US-Mint-Hotels.0-l502551-0.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-Best-Western.0-n800129-0--bBestWestern.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-Hilton-Hotels.0-n800129-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Kimpton Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-Kimpton-Hotels.0-n800129-0--bKimptonHotels.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-La-Quinta-Inn-Suites.0-n800129-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Union Square Hotels](https://www.expedia.ca/Union-Square-San-Francisco-Hotels.0-n800129-0.Travel-Guide-Filter-Hotels) - [Flights to San Francisco](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights) - [Flights from Vancouver (YVR) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco) - [Flights from Toronto (YYZ) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco) - [Mission Dolores Park](https://www.expedia.ca/Mission-Dolores-Park-Mission-District.d6227863.Vacation-Attraction) - [Mission San Francisco de Asís](https://www.expedia.ca/Mission-San-Francisco-De-Asis-Mission-District.d553248634285122123.Vacation-Attraction) - [Sfjazz Center](https://www.expedia.ca/SFJAZZ-Center-Civic-Center.d6265863.Vacation-Attraction) - [Visit Bernal Heights](https://www.expedia.ca/San-Francisco-Bernal-Heights.dx553248621561136356) - [Visit Castro District](https://www.expedia.ca/San-Francisco-Castro-District.dx179363) - [Visit Downtown San Francisco](https://www.expedia.ca/San-Francisco-Downtown-San-Francisco.dx6151902) - [Visit Eureka Valley](https://www.expedia.ca/San-Francisco-Eureka-Valley.dx553248635976472147) - [Visit Noe Valley](https://www.expedia.ca/San-Francisco-Noe-Valley.dx6155705) - [San Francisco Vacations](https://www.expedia.ca/San-Francisco.d178305.Destination-Travel-Guides) - [Car rentals near Castro District](https://www.expedia.ca/Car-Rentals-In-Castro-District.d179363.Car-Rental-Guide) - [Car rentals near Noe Valley](https://www.expedia.ca/Car-Rentals-In-Noe-Valley.d6155705.Car-Rental-Guide) - [Car rentals near San Francisco](https://www.expedia.ca/Car-Rentals-In-San-Francisco.d178305.Car-Rental-Guide) - [Things to do in San Francisco](https://www.expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities) - [Book Hotels in Mission District on Expedia.com](https://www.expedia.com/Mission-District-San-Francisco-Hotels-La-Quinta-Inn-Suites.0-n134035-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)