Title: Hotels by Highgate Independent in Mission Bay from CA $251 | Expedia.ca [Mission Bay Travel Guide](https://expedia.ca/San-Francisco-Mission-Bay.dx553248635976008622)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Mission Bay Car Rentals](https://expedia.ca/Car-Rentals-In-Mission-Bay.d553248635976008622.Car-Rental-Guide)[Mission Bay Vacations](https://expedia.ca/Mission-Bay.d553248635976008622.Destination-Travel-Guides) # Find Hotels by Highgate Independent in Mission Bay from CA $251 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=553248635976008622&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976008622&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976008622&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976008622&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mission Bay Highgate Independent ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/575b2d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/0bf5bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/c37460ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/ac2abcd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Caza Fisherman's Wharf [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) Fisherman's Wharf 9.0/10 Wonderful (3826) "We stay here a lot, great place and safe." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Albert CA $160 CA $251 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) ![City view](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/8ee09bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily self-serve breakfast for a fee](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/51015b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/dfb4e12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/f2cd06dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stanford Court San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Stanford-Court-San-Francisco.h6271901.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (1336) "Great room, great view, always clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward CA $178 CA $271 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/San-Francisco-Hotels-Stanford-Court-San-Francisco.h6271901.Hotel-Information) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/864/9c354d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, eco-friendly toiletries, hair dryer, bathrobes](https://images.trvl-media.com/lodging/1000000/10000/900/864/7183caa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/864/e5133fd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/864/28561d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Huntington Hotel [](https://www.expedia.ca/San-Francisco-Hotels-Huntington-Hotel.h864.Hotel-Information) Downtown San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Huntington-Hotel.h864.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27®ionId=553248635976008622&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMission-Bay-San-Francisco-Hotels-Highgate-Independent.0-n553248635976008622-0--bHighgateIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMission-Bay-San-Francisco-Hotels-Highgate-Independent.0-n553248635976008622-0--bHighgateIndependent.Travel-Guide-Filter-Hotels) ## Top Mission Bay Hotel Reviews ![The Marina Inn on San Francisco Bay](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/095a2e83_y.jpg) ### The Marina Inn on San Francisco Bay 10/10 Excellent "Clean, cozy, great staff!" [](https://expedia.ca/Oakland-Hotels-The-Marina-Inn-On-San-Francisco-Bay.h51116.Hotel-Information) ![DoubleTree by Hilton Hotel Berkeley Marina](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg) ### DoubleTree by Hilton Hotel Berkeley Marina 10/10 Excellent "Staff was nice. Got a fresh warm chocolate chip cookie upon entrance. Clean room. Would recommend " [](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![FOUND Hotel Carlton, Nob Hill](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/818bb89d_y.jpg) ### FOUND Hotel Carlton, Nob Hill 10/10 Excellent "Staff are considerate, friendly, knowledgeable to name a few. They and the hotel make my stay comfortable and I feel safe. " [](https://expedia.ca/San-Francisco-Hotels-FOUND-Hotel-San-Francisco-Carlton.h103126565.Hotel-Information) ![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "All of it was great! We will definitely stay again. " [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Holiday Inn Golden Gateway by IHG](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "Service was great!! Might be a bit noisy walls are thin but it's good. " [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Hyatt Place San Francisco Downtown](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/fc76649d_y.jpg) ### Hyatt Place San Francisco Downtown 10/10 Excellent "Room was small (hey, it's the city) but clean and well-appointed. Staff was great. Nice location close to the water." [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information) ![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg) ### Hilton San Francisco Financial District 10/10 Excellent "Always great stay. Great staff, nice and clean rooms. " [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![LUMA Hotel San Francisco ](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/f72650f9_y.jpg) ### LUMA Hotel San Francisco 10/10 Excellent "Excellent location and room was spacious, clean and very comfortable bed. We will definitely stay here again! Great, friendly staff was an added bonus! " [](https://expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) ![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "Wonderful " [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ## Find out more about Mission Bay ## Mission Bay Hotels Guide Expedia.ca offers a selection of 4861 hotels in Mission Bay. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Mission Bay. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Mission Bay neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Mission Bay, San Francisco now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Aparthotels in 20th Street Station ](https://www.expedia.ca/20th-Street-Station-Apart-Hotels.d553248635996308275-aaApartHotels.Travel-Guide-Accommodation) - [Hotels near Academy of Art University ](https://www.expedia.ca/Academy-Of-Art-University-Hotels.0-l6151906-0.Travel-Guide-Filter-Hotels) - [Hotels near Brannan Street Wharf ](https://www.expedia.ca/Brannan-Street-Wharf-Hotels.0-l553248621533114867-0.Travel-Guide-Filter-Hotels) - [Hotels near California College of the Arts ](https://www.expedia.ca/California-College-Of-The-Arts-Hotels.0-l553248621533113930-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Central Waterfront ](https://www.expedia.ca/Central-Waterfront-San-Francisco-Hotels-Luxury-Hotel.0-n553248635976473156-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Central Waterfront Hotels ](https://www.expedia.ca/Central-Waterfront-San-Francisco-Hotels.0-n553248635976473156-0.Travel-Guide-Filter-Hotels) - 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