Title: Mill Creek Vacation Home Rentals from CA $142: Search Top Private Vacation Homes for Rent | Expedia.ca [Hotels in Mill Creek](https://expedia.ca/Mill-Creek-Hotels.d553248634983184557.Travel-Guide-Hotels)[Vacation Rentals in Mill Creek](https://expedia.ca/Mill-Creek-Vacation-Rentals.d553248634983184557.Travel-Guide-VacationRentals)[Mill Creek Car Rentals](https://expedia.ca/Car-Rentals-In-Mill-Creek.d553248634983184557.Car-Rental-Guide)[Mill Creek Vacation Packages](https://expedia.ca/Mill-Creek.d553248634983184557.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Mill Creek Vacation Rentals ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248634983184557&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248634983184557&startDate=2025-10-31&endDate=2025-11-02&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248634983184557&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248634983184557&startDate=2025-12-12&endDate=2025-12-14&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Mill Creek Vacation Homes ![Interior](https://images.trvl-media.com/lodging/92000000/91590000/91586000/91585902/w903h683x60y0-ba97aead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91590000/91586000/91585902/w905h683x59y0-aa3da30c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91590000/91586000/91585902/w517h683x259y0-ae0660ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91590000/91586000/91585902/w906h683x60y0-38b65c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded treehouse with indoor fireplace Makanda 10/10 Exceptional (16) "Beautiful place! Right down the road to three of the major wineries on the Shawnee Wine Trail and with in 20 min or so of all the others. Great location, beautiful place!" CA $177 CA $277 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Makanda-Hotels-Secluded-Treehouse-With-Indoor-Fireplace.h91585902.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/bcbc8581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/81932f13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/5e48ce91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/1136aaf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool Cape Girardeau 8.8/10 Excellent (34) "Abbie was an amazing hostess. She was great with communicating with our group and made our stay awesome. She was very accommodating and made sure we had everything we needed to make our trip perfect. The house and pool were great. We were very pleased. " CA $190 CA $299 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/ad11073b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/927199d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/1e8bea93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Blue Cottage on Spanish Cape Girardeau 8.6/10 Excellent (43) "We enjoy every time we stay here . We have stayed her many times. There is some repairs that need to be done . Also I think there needs to be a better way to cook besides a microwave. " CA $114 CA $142 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) ![WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/8f220eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/240487da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/w1320h989x0y0-73e73ec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/d10dae1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom with AC, WiFi in lovely Jonesboro Jonesboro 10/10 Exceptional (1) "Our stay at 1898 was lovely!! Clean and comfortable! Will stay again when we head back south to visit family! Thank you!!! " CA $169 CA $375 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Jonesboro-Hotels-Charming-2-Bedroom-With-AC.h118734902.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/29617056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/ec557893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/6b76cbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity South -- Gardens, River-Views, and Refreshing Space Cape Girardeau 10/10 Exceptional (144) "Beautiful house. Great stay. Would definitely stay again!" CA $211 CA $344 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/dc959c59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/54de22e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/f42a73b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/d1b53ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Next Door to Mercy Hospital - Pet Friendly - Fast Wifi Cape Girardeau 8.0/10 Very good (5) "Great place for our family to have a quick get together in short notice." CA $230 CA $560 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Next-Door-To-Mercy-Hospital-Pet-Friendly-Fast-Wifi.h103701368.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/122000000/121400000/121397000/121396978/885132e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121400000/121397000/121396978/f73eef97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121400000/121397000/121396978/d82ff213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121400000/121397000/121396978/c957be49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass Alto Pass CA $246 CA $370 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Alto-Pass-Hotels-Walk-To-Weddings-Wineries-Trails.h121396978.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/1d3d3325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/2fc99c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/4d2e92b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/bb0c0319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Farm Cottage at Rendleman Orchards Alto Pass 9.6/10 Exceptional (5) "The setting of this well appointed cottage is just lovely. The cottage is fully equipped with anything you might need, plus there are all kinds of fun extras like classic albums and stereo, an outside grill and seating area, and a pond you can gaze at from a private porch swing. We loved being nestled among the peach trees and visiting the chicken coop in the morning. The beds are very comfortable and the “convenient store” is a great feature. We look forward to staying here again since our... CA $315 CA $386 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Alto-Pass-Hotels-Farm-Immersion-Experience-At-Rendleman-Orchards.h117036792.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/2cc8556c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/77eb14c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/d2b33581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/07e510a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More Cape Girardeau 9.6/10 Exceptional (7) "Nice place, great times" CA $378 CA $614 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Cape-Girardeau-Hotels-4-Bedroom-Home-2-King-Beds.h111971489.Hotel-Information) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/81000000/80930000/80928000/80927992/cb1d033f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/81000000/80930000/80928000/80927992/c88c8141.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/81000000/80930000/80928000/80927992/39b31aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/81000000/80930000/80928000/80927992/77d925e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private bluffs, 40-mile view on Shawnee Wine Trail Buncombe 10/10 Exceptional (154) "We love the house, the environment. We had so much fun! " CA $449 CA $566 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Buncombe-Hotels-Private-Bluffs.h80927992.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/1c6c31ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/7dffb73b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/450d2061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/d39634e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Building at Cape Girardeau Regional Airport Scott City CA $702 CA $858 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Scott-City-Hotels-Building-At-Cape-Girardeau-Regional-Airport.h103892640.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=553248634983184557&adults=2&lodging=VACATION_HOME&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMill-Creek-Private-Vacation-Homes.d553248634983184557-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMill-Creek-Private-Vacation-Homes.d553248634983184557-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Mill Creek Hotel Reviews ![Candlewood Suites Cape Girardeau by IHG](//images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg) ### Candlewood Suites Cape Girardeau by IHG 10/10 Excellent "Clean room and bathroom, the beds and pillows were comfortable, the bathroom and the room were both really spacious which my toddler loved after being in her car seat she had plenty of room to run freely. The location was safe as well and convenient having a Rhodes close by open late to get snacks and chargers. I was pleased with my stay I felt safe and comfortable." [](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Quality Inn](//images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn 10/10 Excellent "It was so welcoming and peaceful" [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Room was a bit on the small side, but comfortable." [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Hampton Inn Cape Girardeau I 55 East](//images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d_y.jpg) ### Hampton Inn Cape Girardeau I 55 East 10/10 Excellent "Excellent Breakfast. Everything about this inn was top notch." [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Great staff " [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Very tasty buffet-style food every morning and evening, the suites were large & clean. All of the staff members were friendly & helpful: From the people at the front desk, to the folks preparing the food, to the housekeeping staff keeping the rooms and public areas all nice & tidy. 5 Stars!" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Clean room. " [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased. " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe " [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ## Find out more about Mill Creek ## Mill Creek Vacation Homes information | Number of reviews | 385 | | --- | --- | | Accommodation | 60 Vacation Homes | | Lowest Price | CA $142 | | Highest Price | CA $858 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in West Vienna](https://www.expedia.ca/3Star-West-Vienna-Hotels.s30-0-d553248635975864465.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Pomona](https://www.expedia.ca/5Star-Pomona-Hotels.s50-0-d553248635592817265.Travel-Guide-Filter-Hotels) - [Apartments in Alto Pass](https://www.expedia.ca/Alto-Pass-Apartments.d73449-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in Alto Pass](https://www.expedia.ca/Alto-Pass-Cabins.d73449-aaCabins.Travel-Guide-Accommodation) - [Alto Pass Hotels](https://www.expedia.ca/Alto-Pass-Hotels.d73449.Travel-Guide-Hotels) - 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