Title: Book the Best BUSINESS Hotels in Midway-Pacific Highway in 2026 | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Midway-Pacific Highway Car Rentals](https://expedia.ca/Car-Rentals-In-Midway-Pacific-Highway.d553248633938969446.Car-Rental-Guide)[Midway-Pacific Highway Vacations](https://expedia.ca/Midway-Pacific-Highway.d553248633938969446.Destination-Travel-Guides) ![Balboa park Botanical garden plants and flower exhibits San Diego.](https://images.trvl-media.com/place/553248633938969446/b58b1cbe-1484-49ab-8b9d-5361eae6f2c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248633938969446/b58b1cbe-1484-49ab-8b9d-5361eae6f2c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Midway-Pacific Highway Business Hotels Tonight [Jan 28 - Jan 29](https://www.expedia.ca/Hotel-Search?regionId=553248633938969446&startDate=2026-01-28&endDate=2026-01-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=553248633938969446&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248633938969446&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248633938969446&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Midway-Pacific Highway business-friendly hotels ![Reception](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/w3836h2556x4y4-7bc1025b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Courtyard View | Courtyard view](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/5f757a25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/w3837h2560x3y0-23cd0701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town [](https://www.expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) Point Loma 9.2/10 Wonderful (574 reviews) "Great place to stay, nice room Highly recommended !!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wilfredo CA $168 CA $193 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/41000/40962/87da6900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41000/40962/143ad063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/41000/40962/622df597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden San Diego Near SeaWorld [](https://www.expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) Point Loma 7.4/10 Good (4,171 reviews) "Good location friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anya CA $122 CA $140 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/550000/544700/544662/1f164db1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/550000/544700/544662/44f458a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/550000/544700/544662/14702cd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/550000/544700/544662/7a4f772e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Sea World Area [](https://www.expedia.ca/San-Diego-Hotels-Comfort-Inn-Sea-World-Area.h544662.Hotel-Information) Point Loma 8.6/10 Excellent (3,295 reviews) "Nice beds and breakfast, really convenient " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Margarita CA $114 CA $131 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/San-Diego-Hotels-Comfort-Inn-Sea-World-Area.h544662.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/90271416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/9ad1416a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/a98dc1ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/d9796ad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn San Diego [](https://www.expedia.ca/San-Diego-Hotels-Heritage-Inn-San-Diego-Near-SeaWorld.h2202716.Hotel-Information) Point Loma 7.4/10 Good (1,221 reviews) "It was clean an pretty close from airport" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hortencia CA $81 CA $94 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/San-Diego-Hotels-Heritage-Inn-San-Diego-Near-SeaWorld.h2202716.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/64000000/63700000/63693600/63693503/1375ee6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63700000/63693600/63693503/b54b7782.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Jacuzzi Suite](https://images.trvl-media.com/lodging/64000000/63700000/63693600/63693503/04a67c56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/64000000/63700000/63693600/63693503/f3d22bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Old Town Inn [](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Inn.h63693503.Hotel-Information) Point Loma 9.2/10 Wonderful (1,810 reviews) "Clean room, good breakfast, good location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joan CA $188 CA $216 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Inn.h63693503.Hotel-Information) ![Suite, Multiple Beds](https://images.trvl-media.com/lodging/1000000/10000/1700/1676/82ad126a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/1700/1676/cc4fff3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/1700/1676/3b158110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1700/1676/f3eb79df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express San Diego - SeaWorld Area by IHG [](https://www.expedia.ca/San-Diego-Hotels-Holiday-Inn-Express-San-Diego-SeaWorld-Area.h1676.Hotel-Information) Point Loma 8.8/10 Excellent (1,001 reviews) "very spacious room very clean close to everything restaurant stores Central located." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Walter CA $200 CA $230 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/San-Diego-Hotels-Holiday-Inn-Express-San-Diego-SeaWorld-Area.h1676.Hotel-Information) ![1 bedroom, hypo-allergenic bedding, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/130000/123400/123394/0448ea8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/130000/123400/123394/1e576975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/130000/123400/123394/fba66004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/123400/123394/5bb9f207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham San Diego SeaWorld [](https://www.expedia.ca/San-Diego-Hotels-Travelodge-By-Wyndham-San-Diego-SeaWorld.h123394.Hotel-Information) Point Loma 6.2/10 (1,000 reviews) "Nice and short stay." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) ANGEL CA $92 CA $104 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/San-Diego-Hotels-Travelodge-By-Wyndham-San-Diego-SeaWorld.h123394.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/440000/436200/436197/e51745f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/440000/436200/436197/bfaf172e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/440000/436200/436197/68f60f18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/436200/436197/20531378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham San Diego Sea World [](https://www.expedia.ca/San-Diego-Hotels-Howard-Johnson-By-Wyndham-San-Diego-Sea-World.h436197.Hotel-Information) Point Loma 6.6/10 (1,007 reviews) "Always a pleasure to stay at Howard Johnson’s the bed was comfortable and everything is close by. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reyna CA $114 CA $133 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/San-Diego-Hotels-Howard-Johnson-By-Wyndham-San-Diego-Sea-World.h436197.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking, Bay View](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/1a09735e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/1e0934c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/3eeea039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The DEXTRO Little Italy, BW Premier Collection [](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) Downtown San Diego 9.0/10 Wonderful (981 reviews) "Clean rooms and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Topeka CA $163 CA $190 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/77d3b0aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/b0a789a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/9eb7273b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bay Club Hotel & Marina [](https://www.expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) Point Loma 9.2/10 Wonderful (3,329 reviews) "We had great time and enjoyed our stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sadra CA $172 CA $198 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-11&endDate=2026-02-12®ionId=553248633938969446&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Midway-Pacific Highway Hotel Reviews ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "Great little spot, also very. close to Little Italy farmers market. The staff was very friendly and accommodating. if need a place for a quick get a way this is it. " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Hampton Inn & Suites by Hilton San Diego SeaWorld](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "Clean room, comfortable bed and pillow. Spacious and updated." [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "staff were friendly and accommodating." [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Great hotel!! In the middle of Little Italy. Very walkable. The bar staff were fantastic!" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Paradise Point Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/bc1e5add_y.jpg) ### Paradise Point Resort & Spa 10/10 Excellent "Clean. Great location. Hidden treasure. Heated pools. " [](https://expedia.ca/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Great stay! " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Everything went good " [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Everything looks great " [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Room was clean and restocked daily. Staff was very courteous." 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