Title: Book the Best Midtown LUXURY Hotels - Upscale Hotels in Midtown, San Antonio | Expedia.ca [Vacation Rentals in San Antonio](https://expedia.ca/San-Antonio-Vacation-Rentals.d178303.Travel-Guide-VacationRentals)[Flights to San Antonio](https://expedia.ca/Cheap-Flights-To-San-Antonio.d178303.Travel-Guide-Flights)[Things to do in San Antonio](https://expedia.ca/Things-To-Do-In-San-Antonio.d178303.Travel-Guide-Activities)[Midtown Car Rentals](https://expedia.ca/Car-Rentals-In-Midtown.d553248633938969302.Car-Rental-Guide)[Midtown Vacations](https://expedia.ca/Midtown.d553248633938969302.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/507000/507652-brackenridge-park.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Midtown, San Antonio ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Midtown Luxury Hotels Tonight [Oct 28 - Oct 29](https://www.expedia.ca/Hotel-Search?regionId=553248633938969302&startDate=2025-10-28&endDate=2025-10-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=553248633938969302&startDate=2025-10-29&endDate=2025-10-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248633938969302&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248633938969302&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Midtown Luxury Hotels ## Top Midtown Hotel Reviews ## Frequently asked questions ### Are you searching for a great accommodation for your luxury trip to Midtown? > Use Expedia to arrange your flight to San Antonio International Airport (SAT) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you want to make your stay special. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Midtown offers. During your visit, you might want to enjoy the bars which Midtown is known for. ### What's there to see and do in Midtown? > When you're in Midtown, enjoy exploring the sights and attractions here including The DoSeum, San Antonio Zoo and Aquarium, and San Antonio River. If you have a bit of extra time while you're in the area, you might want to check out Historic Brackenridge Golf Course and McFarlin Tennis Center. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [4 Star Hotels in Five Points](https://www.expedia.ca/4Star-Five-Points-San-Antonio-Hotels.s40-n553248635976395455-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in River Road](https://www.expedia.ca/5Star-River-Road-San-Antonio-Hotels.s50-n553248635976387148-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Tobin Hill](https://www.expedia.ca/5Star-Tobin-Hill-San-Antonio-Hotels.s50-n553248635976386526-0.Travel-Guide-Filter-Hotels) - [Family Hotels in Alamo Plaza](https://www.expedia.ca/Alamo-Plaza-Hotels-Family-Hotel.0-0-d6229132-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Alta Vista Hotels](https://www.expedia.ca/Alta-Vista-San-Antonio-Hotels.0-n553248635976470375-0.Travel-Guide-Filter-Hotels) - [Business Hotels in Austin](https://www.expedia.ca/Austin-Hotels-Business-Hotel.0-0-d178234-tBusinessHotel.Travel-Guide-Filter-Hotels) - 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