Title: Book the Best BUSINESS Hotels in Midtown in 2026 | Expedia.ca [Midtown Travel Guide](https://expedia.ca/Houston-Midtown.dx6282039)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Midtown Car Rentals](https://expedia.ca/Car-Rentals-In-Midtown.d6282039.Car-Rental-Guide)[Midtown Vacations](https://expedia.ca/Midtown.d6282039.Destination-Travel-Guides) ![Taken from the back parking garage. ](https://images.trvl-media.com/place/1503/c78fddf6-c308-473d-b348-f8218b064137.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by George Zimzores # Find Business Hotels in Midtown, TX from CA $115 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Midtown Business Hotels Tonight [Dec 22 - Dec 23](https://www.expedia.ca/Hotel-Search?regionId=6282039&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 23 - Dec 24](https://www.expedia.ca/Hotel-Search?regionId=6282039&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6282039&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6282039&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Midtown business-friendly hotels ![Outdoor dining](https://images.trvl-media.com/lodging/49000000/48370000/48365300/48365278/c45795b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/49000000/48370000/48365300/48365278/4bfe571e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/49000000/48370000/48365300/48365278/3e6b02d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/49000000/48370000/48365300/48365278/a5d81b61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fully stocked, Modern & Cosy Studio with Patio. Best Location! Walk Everywhere! [](https://www.expedia.ca/Houston-Hotels-Vrbo-Property.h48365278.Hotel-Information) Midtown 9.8/10 Exceptional (78) "Great place, great location. Easy communication! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carly R. CA $81 CA $179 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Houston-Hotels-Vrbo-Property.h48365278.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12030000/12021700/12021677/f1f7afb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Private Bathroom (Room 203B) | Living area](https://images.trvl-media.com/lodging/13000000/12030000/12021700/12021677/1b3590bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12030000/12021700/12021677/7f5ee6d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/13000000/12030000/12021700/12021677/57507fc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Maison in Midtown an urban B&B [](https://www.expedia.ca/Houston-Hotels-La-Maison-In-Midtown-An-Urban-Bed-And-Breakfast.h12021677.Hotel-Information) Midtown 9.8/10 Exceptional (542) "great neighborhood, friendly staff, and delicious breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna CA $222 CA $260 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Houston-Hotels-La-Maison-In-Midtown-An-Urban-Bed-And-Breakfast.h12021677.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/76e7278c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/c1fa2b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/aa7fafd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Quarters Hotel Downtown, Houston [](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) Downtown Houston 8.4/10 Very good (3965) "Rooms were great and the staff was absolutely amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elmer CA $99 CA $115 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/b50fb68f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/fc0f10cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/2c21a287.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/1c27d1d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Pearland/Houston Medical Center Hotel [](https://www.expedia.ca/Houston-Hotels-Best-Western-Plus-PearlandHouston-Medical-Center-Hotel.h115550694.Hotel-Information) Southeast Houston 9.4/10 Exceptional (58) "Very nice and clean staff was great!!! Will vist again if im in that area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roderick CA $111 CA $129 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Houston-Hotels-Best-Western-Plus-PearlandHouston-Medical-Center-Hotel.h115550694.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/117000000/116470000/116463400/116463331/61b3b5fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116470000/116463400/116463331/f1f8c97a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/117000000/116470000/116463400/116463331/fe8e8232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/117000000/116470000/116463400/116463331/398b6de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Humble Intercontinental Airport [](https://www.expedia.ca/Houston-Hotels-TownePlace-Suites-By-Marriott-Humble-Intercontinental-Airport.h116463331.Hotel-Information) Humble 9.6/10 Exceptional (96) "very nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bernardo CA $139 CA $164 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Houston-Hotels-TownePlace-Suites-By-Marriott-Humble-Intercontinental-Airport.h116463331.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/w3836h2556x4y4-d736e03c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/b032cc4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, City View | View from room](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/a6761ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Royal Sonesta Houston Galleria [](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) The Galleria 8.4/10 Very good (1476) "Wonderful hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debbie CA $151 CA $177 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f8ddb5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f2e085ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/12af8c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Plaza/Medical Center [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) Texas Medical Center 8.4/10 Very good (1780) "Clean rooms, comfortable bed, & friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $121 CA $143 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/8cd55d48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/3785f3f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/024118ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel [](https://www.expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) Downtown Houston 9.2/10 Wonderful (1349) "Bed was very nice and comfortable! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis CA $155 CA $186 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/66da1da6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/9adf18be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/ba58a987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/70d04980.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Houston Intercontinental Airport [](https://www.expedia.ca/Houston-Hotels-Courtyard-By-Marriott-Houston-Intercontinental-Airport.h19716268.Hotel-Information) Houston 9.0/10 Wonderful (1086) "Courteous staff, clean rooms, excellent location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca CA $140 CA $163 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Houston-Hotels-Courtyard-By-Marriott-Houston-Intercontinental-Airport.h19716268.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/a72ac5b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2505x3y0-1cfabad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/40a5bc26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/db7ae93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blossom Hotel Houston, Curio Collection by Hilton [](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) Texas Medical Center 9.0/10 Wonderful (3616) "Cute hotel, very clean and friendly staff. We enjoyed our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alison CA $180 CA $211 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-05&endDate=2026-01-06®ionId=6282039&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Midtown Hotel Reviews ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "Great" [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![DoubleTree by Hilton Hotel Houston - Greenway Plaza](https://images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg) ### DoubleTree by Hilton Hotel Houston - Greenway Plaza 10/10 Excellent "Very clean. Very nice hotel. " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information) ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "Love the staff, the property is so nice and clean and safe!!!! " [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 10/10 Excellent "Wonderful and the staff was awesome " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) ![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191_y.jpg) ### Crowne Plaza Houston Med Ctr-Galleria Area by IHG 10/10 Excellent "The room was very clean and spacious. Comfortable bed " [](https://expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information) ![Omni Houston Hotel](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/37423ee4_y.jpg) ### Omni Houston Hotel 10/10 Excellent "Great location, clean rooms and friendly staff" [](https://expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information) ![The Whitehall Houston](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg) ### The Whitehall Houston 10/10 Excellent "Great hotel and friendly staff" [](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ![The Westin Galleria Houston](https://images.trvl-media.com/lodging/1000000/20000/11200/11117/b45a8086_y.jpg) ### The Westin Galleria Houston 10/10 Excellent "Great location" [](https://expedia.ca/Houston-Hotels-The-Westin-Galleria-Houston.h11117.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 10/10 Excellent "yes" [](https://expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in Midtown with Expedia? ### How can I find cheap business-friendly hotels in Midtown? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [5 Star Hotels in Houston ](https://www.expedia.ca/5Star-Houston-Hotels.s50-0-d178265.Travel-Guide-Filter-Hotels) - [Hotels near Continental Club ](https://www.expedia.ca/Continental-Club-Hotels.0-l553248621533124447-0.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Harris County ](https://www.expedia.ca/Destinations-In-Harris-County-Beach-Hotel.0-0-d553248635975094933-tBeachHotel.Hotel-Filter-Destinations) - [Cheap Hotels in Harris County ](https://www.expedia.ca/Destinations-In-Harris-County-Cheap-Hotels.0-0-d553248635975094933-tCheapHotels.Hotel-Filter-Destinations) - [Hotels with a Pool in Harris County ](https://www.expedia.ca/Destinations-In-Harris-County-Hotel-With-Pool.0-0-d553248635975094933-tHotelwithPool.Hotel-Filter-Destinations) - [Luxury Hotels in Harris County ](https://www.expedia.ca/Destinations-In-Harris-County-Luxury-Hotel.0-0-d553248635975094933-tLuxuryHotel.Hotel-Filter-Destinations) - [Harris County Hotels ](https://www.expedia.ca/Destinations-In-Harris-County.d553248635975094933.Hotel-Destinations) - [Hotels near Discovery Green ](https://www.expedia.ca/Discovery-Green-Hotels.0-l6082195-0.Travel-Guide-Filter-Hotels) - [Downtown Houston Hotels ](https://www.expedia.ca/Downtown-Houston-Houston-Hotels.0-n800037-0.Travel-Guide-Filter-Hotels) - [Fourth Ward Hotels ](https://www.expedia.ca/Fourth-Ward-Houston-Hotels.0-n553248635976395435-0.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Galveston ](https://www.expedia.ca/Galveston-Hotels-Couples-Resorts-Hotels.0-0-d1341-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts and in Galveston ](https://www.expedia.ca/Galveston-Hotels-Honeymoon-Hotels.0-0-d1341-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [Hotels with Childcare in Galveston ](https://www.expedia.ca/Galveston-Hotels-Hotels-With-Childcare.0-0-d1341-tHotelswithChildcare.Travel-Guide-Filter-Hotels) - [Hotels with Tennis Courts in Galveston ](https://www.expedia.ca/Galveston-Hotels-Hotels-With-Tennis-Courts.0-0-d1341-tHotelswithTennisCourts.Travel-Guide-Filter-Hotels) - [Hotels near George R. 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