Title: Book the Best BUSINESS Hotels in Middletown in 2026 | Expedia.ca [Hotels in Middletown](https://expedia.ca/Middletown-Hotels.d8865.Travel-Guide-Hotels)[Vacation Rentals in Middletown](https://expedia.ca/Middletown-Vacation-Rentals.d8865.Travel-Guide-VacationRentals)[Flights to Middletown](https://expedia.ca/Cheap-Flights-To-Middletown.d8865.Travel-Guide-Flights)[Middletown Car Rentals](https://expedia.ca/Car-Rentals-In-Middletown.d8865.Car-Rental-Guide)[Middletown Vacation Packages](https://expedia.ca/Middletown.d8865.Destination-Travel-Guides) ![Three Mile Island Panoramic](https://images.trvl-media.com/place/8865/85b4c51e-dac4-4b64-a769-bee1cbb76c01.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Middletown, PA from CA $77 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Middletown Business Hotels Tonight [Dec 9 - Dec 10](https://www.expedia.ca/Hotel-Search?regionId=8865&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=8865&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=8865&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=8865&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Middletown business-friendly hotels ![Property amenity](https://images.trvl-media.com/lodging/25000000/24160000/24152600/24152526/d0fba356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24160000/24152600/24152526/ef7d8e09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/25000000/24160000/24152600/24152526/590ca801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/25000000/24160000/24152600/24152526/173d172a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Harrisburg International Airport Middletown 9.2/10 Wonderful (1006) "Friendly staff, clean room and perfect location to the airport." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerilyn CA $173 CA $192 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Middletown-Hotels-Fairfield-Inn-Suites-By-Marriott-Harrisburg-International-Airport.h24152526.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/23000000/22790000/22789100/22789073/0e5d5f86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/23000000/22790000/22789100/22789073/90dff5fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/23000000/22790000/22789100/22789073/0082142e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/23000000/22790000/22789100/22789073/e765a957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites – Harrisburg Airport – Hershey South Middletown 9.2/10 Wonderful (1004) "Spacious room, friendly staff, near airport, clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Szarka CA $175 CA $195 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Middletown-Hotels-Comfort-Inn-Suites-Harrisburg-Airport-Hershey-South.h22789073.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17900/17886/b0776368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/17900/17886/464220e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/17900/17886/1942bedf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/20000/17900/17886/w3840h2557x0y2-a653d32f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Harrisburg East by IHG Middletown 7.4/10 Good (938) "It was nice for the price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $108 CA $120 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Middletown-Hotels-Holiday-Inn-Harrisburg-East.h17886.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/64200/64120/35928ddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio Suite, 1 Queen Bed with Sofa bed](https://images.trvl-media.com/lodging/1000000/70000/64200/64120/1b49ea17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/64200/64120/276d5e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/64200/64120/e892c035.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Larkspur Landing Select Carlisle Carlisle 9.0/10 Wonderful (1007) "Clean, great staff and amenities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl CA $101 CA $113 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Carlisle-Hotels-Larkspur-Landing-Select-Carlisle.h64120.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/54000000/53960000/53955900/53955835/f45f96e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53960000/53955900/53955835/30ae7304.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53960000/53955900/53955835/b8584d26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/54000000/53960000/53955900/53955835/cf950449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Grantville, PA Grantville 9.0/10 Wonderful (829) "Amazing stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Simeon CA $88 CA $97 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Harrisburg-Hershey-Hotels-Tru-By-Hilton-Grantville.h53955835.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1550000/1549800/1549728/abb2a00f_edited_d462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1550000/1549800/1549728/d284105f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1550000/1549800/1549728/d00fb6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1550000/1549800/1549728/6e926045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Appalachian Hotel Carlisle 7.2/10 Good (185) "Beautiful accommodations. Comfortable bed and well kept property. Would totally recommend to anyone driving through. Super quiet area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $71 CA $79 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Carlisle-Hotels-Quality-Inn.h1549728.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1098100/1098098/dcbdbb0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1100000/1098100/1098098/070894df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1098100/1098098/334fc60c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/2000000/1100000/1098100/1098098/905e5586.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Lancaster Amish Country Lancaster 7.6/10 Good (1054) "Friendly staff Good breakfast options Lots of dining options around the area Great cleanliness " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jagrutibahen CA $93 CA $103 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Lancaster-Hotels-Days-Inn-Suites-By-Wyndham-Lancaster-Amish-Country.h1098098.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/a37400d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/w1927h819x0y0-dd58c9ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/3ee5be52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/6b01f10d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Mechanicsburg Mechanicsburg 8.2/10 Very good (46) "Very good hotel definitely would recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany CA $110 CA $122 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Mechanicsburg-Hotels-Spark-By-Hilton-Mechanicsburg.h85204.Hotel-Information) ![Seasonal outdoor pool, open 10:00 AM to 8:30 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/20000/11800/11790/39513b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/11800/11790/a59aceb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11800/11790/efe7da96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/11800/11790/0e788116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Harrisburg Harrisburg 8.6/10 Excellent (1713) "Nice place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deanna CA $69 CA $77 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Harrisburg-Hotels-Baymont-By-Wyndham-Harrisburg.h11790.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21271/227a0c5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21300/21271/d7fa27e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21300/21271/cb8e262a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21271/86095b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Escape Inn Hershey Hershey 8.8/10 Excellent (1423) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy [](https://www.expedia.ca/Hershey-Hotels-HersheyScape-Inn.h21271.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-24&endDate=2025-12-25®ionId=8865&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Middletown Hotel Reviews ![Ramada by Wyndham Harrisburg/Hershey Area](https://images.trvl-media.com/lodging/1000000/10000/9800/9731/fcb938a6_y.jpg) ### Ramada by Wyndham Harrisburg/Hershey Area 10/10 Excellent "Building was clean, staff was friendly and the whole place was nice and tidy. The hot tub was relaxing and I had such a pleasant time there relaxing. Love staying here!" [](https://expedia.ca/Harrisburg-Hotels-Ramada-By-Wyndham-HarrisburgHershey-Area.h9731.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Harrisburg-Hershey](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087809/88f568bf_y.jpg) ### La Quinta Inn & Suites by Wyndham Harrisburg-Hershey 10/10 Excellent "Overall great experience! The room, the breakfast, and check in. If anything I would say the pool and hot tub could use some minor upgrades but I did enjoy it. I will return for another night when in town. " [](https://expedia.ca/Harrisburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Harrisburg-Hershey.h5087809.Hotel-Information) ![Country Inn & Suites by Radisson, Harrisburg - Hershey West, PA](https://images.trvl-media.com/lodging/3000000/2560000/2553600/2553577/9a8d0d0b_y.jpg) ### Country Inn & Suites by Radisson, Harrisburg - Hershey West, PA 10/10 Excellent "Yes" [](https://expedia.ca/Harrisburg-Hotels-Country-Inn-Suites-By-Radisson.h2553577.Hotel-Information) ![Days Inn by Wyndham Hershey](https://images.trvl-media.com/lodging/1000000/20000/16000/15999/3a620bf0_y.jpg) ### Days Inn by Wyndham Hershey 10/10 Excellent "Cleaning and hotel staff were very polite and helpful." [](https://expedia.ca/Hershey-Hotels-Days-Inn-By-Wyndham-Hershey.h15999.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Harrisburg Airport Hershey](https://images.trvl-media.com/lodging/1000000/50000/49900/49896/b2b32d38_y.jpg) ### La Quinta Inn & Suites by Wyndham Harrisburg Airport Hershey 10/10 Excellent "Clean room, courteous staff " [](https://expedia.ca/Harrisburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Harrisburg-Airport-Hershey.h49896.Hotel-Information) ![Hampton Inn & Suites Hershey](https://images.trvl-media.com/lodging/1000000/330000/328200/328176/c538899e_y.jpg) ### Hampton Inn & Suites Hershey 10/10 Excellent "Clean and new. Very comfortable stay." [](https://expedia.ca/Hershey-Hotels-Hampton-Inn-Suites-Hershey.h328176.Hotel-Information) ![Homewood Suites by Hilton Harrisburg-West Hershey Area](https://images.trvl-media.com/lodging/1000000/20000/18200/18185/e6f20b13_y.jpg) ### Homewood Suites by Hilton Harrisburg-West Hershey Area 10/10 Excellent "It was a home away from home kinda place. Separate bedroom nice living and kitchen area. The beds were comfy and 24/7 coffee was a huge plus!!!! I highly recommend this hotel. " [](https://expedia.ca/Mechanicsburg-Hotels-Homewood-Suites-By-Hilton-Harrisburg-West-Hershey-Area.h18185.Hotel-Information) ![Red Lion Hotel Harrisburg Hershey](https://images.trvl-media.com/lodging/1000000/20000/11300/11288/a260ea74_y.jpg) ### Red Lion Hotel Harrisburg Hershey 10/10 Excellent "Love it here im planning another trip back " [](https://expedia.ca/Harrisburg-Hotels-Red-Lion-Hotel-Harrisburg-Hershey.h11288.Hotel-Information) ![Courtyard by Marriott Hershey Chocolate Avenue](https://images.trvl-media.com/lodging/19000000/18100000/18090300/18090224/895a7ed6_y.jpg) ### Courtyard by Marriott Hershey Chocolate Avenue 10/10 Excellent "Nice hotel. Very comfortable. Staff excellent. I definitely will be back!" [](https://expedia.ca/Hershey-Hotels-Courtyard-By-Marriott-Hershey-Chocolate-Avenue.h18090224.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Middletown cost? ### What are the best business-friendly hotels in Middletown? ### How many business-friendly hotels are there in Middletown? ### What are the best cheap business-friendly hotels in Middletown? ### Are there any family-friendly hotels in Middletown that are also business friendly? ### Why book your business-friendly hotel in Middletown with Expedia? ### How can I find cheap business-friendly hotels in Middletown? ### What is there to do in Middletown near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [Hotels & Resorts for Couples in Pennsylvania ](https://www.expedia.ca/Destinations-In-Pennsylvania-Couples-Resorts-Hotels.0-0-d240-tCouplesResortsHotels.Hotel-Filter-Destinations) - [Hotels with Early Check-in in Pennsylvania ](https://www.expedia.ca/Destinations-In-Pennsylvania-Hotel-With-Early-Check-In.0-0-d240-thotelwithearlycheckin.Hotel-Filter-Destinations) - 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