Title: Book the Best Mexico LUXURY Hotels - Upscale Hotels in Mexico, MO | Expedia.ca [Mexico Travel Guide](https://expedia.ca/Mexico.dx8832)[Hotels in Mexico](https://expedia.ca/Mexico-Hotels.d8832.Travel-Guide-Hotels)[Vacation Rentals in Mexico](https://expedia.ca/Mexico-Vacation-Rentals.d8832.Travel-Guide-VacationRentals)[Flights to Mexico](https://expedia.ca/Cheap-Flights-To-Mexico.d8832.Travel-Guide-Flights)[Mexico Car Rentals](https://expedia.ca/Car-Rentals-In-Mexico.d8832.Car-Rental-Guide)[Mexico Vacation Packages](https://expedia.ca/Mexico.d8832.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Mexico, MO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mexico Luxury Hotels Tonight [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2025-10-29&endDate=2025-10-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2025-10-30&endDate=2025-10-31&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Mexico Luxury Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/d033dcd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/161b0a31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/4ac397d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/fcdb510e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Mexico Mexico 6.8/10 (294) "Comfortable bed... Didn't like stool loose on base." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marvin CA $107 CA $119 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Columbia-Hotels-Days-Inn-By-Wyndham-Mexico.h151247.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=8832&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Mexico ### Mexicoand its attractions for luxury travelers In the charming town of Mexico, Missouri, luxury travellers can indulge in a variety of enriching experiences. Start your journey at the beautiful Audrain County Historical Society, where you can explore fascinating exhibits that showcase the region's rich heritage, all while enjoying a serene atmosphere. Nature enthusiasts will appreciate the stunning views at the nearby Mark Twain State Park, perfect for leisurely hikes and picnics amidst the picturesque landscapes. For a touch of elegance, treat yourself to a fine dining experience at one of the local upscale restaurants, where you can savour exquisite dishes crafted from fresh, local ingredients. If you're a golf aficionado, the Mexico Country Club offers a beautifully manicured course with stunning views, providing an excellent opportunity to unwind. After a day of exploration, consider staying at a luxurious hotel in the downtown area, where you can enjoy modern amenities and attentive service, ensuring a restful retreat. The combination of rich cultural experiences and comfortable accommodations makes Mexico, Missouri a hidden gem for the discerning traveller. ## Top Mexico Hotel Reviews ![Best Western Plus Columbia Inn](//images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73_y.jpg) ### Best Western Plus Columbia Inn 10/10 Excellent "Muy buena atencion y limpio algo muy importante. " [](https://expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Ramada by Wyndham Columbia](//images.trvl-media.com/lodging/1000000/20000/18900/18803/77d8da33_y.jpg) ### Ramada by Wyndham Columbia 10/10 Excellent "The room was nice specially the bathroom but it did need a bit upkeep to a few spots on walls. Freezer needs to thaw out ice buildup." [](https://expedia.ca/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ![Baymont by Wyndham Fulton](//images.trvl-media.com/lodging/2000000/1090000/1085800/1085736/1c13cf99_y.jpg) ### Baymont by Wyndham Fulton 10/10 Excellent "It was a fine, comfortable place to stay at an affordable price. My only suggestion is that the room television is small by today's standards. " [](https://expedia.ca/Columbia-Hotels-Baymont-By-Wyndham-Fulton.h1085736.Hotel-Information) ![Quality Inn & Suites Columbia I-70](//images.trvl-media.com/lodging/1000000/20000/14600/14520/41147965_y.jpg) ### Quality Inn & Suites Columbia I-70 10/10 Excellent "Overall Good" [](https://expedia.ca/Columbia-Hotels-Quality-Inn-Suites-Columbia-I-70.h14520.Hotel-Information) ![Super 8 by Wyndham Columbia East](//images.trvl-media.com/lodging/2000000/1050000/1044300/1044261/f8795c2e_y.jpg) ### Super 8 by Wyndham Columbia East 10/10 Excellent "The room was great. Check in went smoothly. I had a great stay. " [](https://expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Columbia-East.h1044261.Hotel-Information) ![Hampton Inn & Suites Columbia at University](//images.trvl-media.com/lodging/3000000/2010000/2009600/2009513/2702d693_y.jpg) ### Hampton Inn & Suites Columbia at University 10/10 Excellent "Great " [](https://expedia.ca/Columbia-Hotels-Hampton-Inn-Suites-Columbia-At-University.h2009513.Hotel-Information) ![Red Roof Inn Columbia, MO](//images.trvl-media.com/lodging/1000000/20000/19600/19600/63579173_y.jpg) ### Red Roof Inn Columbia, MO 10/10 Excellent "We slept very well in a comfortable, clean and quiet room at.an amazingly affordable price." [](https://expedia.ca/Columbia-Hotels-Red-Roof-Inn-Columbia.h19600.Hotel-Information) ![Days Inn by Wyndham Mexico](//images.trvl-media.com/lodging/1000000/160000/151300/151247/d033dcd0_y.jpg) ### Days Inn by Wyndham Mexico 10/10 Excellent "Comfortable bed... Didn't like stool loose on base." [](https://expedia.ca/Columbia-Hotels-Days-Inn-By-Wyndham-Mexico.h151247.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury holiday in Mexico? > Let Expedia help you arrange your flight to Columbia, MO (COU-Columbia Regional) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Mexico has to offer. Mexico has some interesting things to see and do including Lakeview Park and Hillside Mini Golf, so you might want to take in the local sights during your visit. ### When can I expect good weather in Mexico? > Planning for the weather is an important factor for making your trip to Mexico a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 35°F. Average annual precipitation for Mexico is 48 inches. ### What's there to see and do in Mexico? > When you're in Mexico, enjoy exploring the sights and attractions here including Lakeview Park, Hillside Mini Golf, and Mexico Audrain County Library. 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