Title: Book the Best Mexico LUXURY Hotels - Upscale Hotels in Mexico, MO | Expedia.ca

[Mexico Travel Guide](https://expedia.ca/Mexico.dx8832)[Hotels in Mexico](https://expedia.ca/Mexico-Hotels.d8832.Travel-Guide-Hotels)[Vacation Rentals in Mexico](https://expedia.ca/Mexico-Vacation-Rentals.d8832.Travel-Guide-VacationRentals)[Flights to Mexico](https://expedia.ca/Cheap-Flights-To-Mexico.d8832.Travel-Guide-Flights)[Mexico Car Rentals](https://expedia.ca/Car-Rentals-In-Mexico.d8832.Car-Rental-Guide)[Mexico Vacation Packages](https://expedia.ca/Mexico.d8832.Destination-Travel-Guides)

![An old historic schoolhouse in Mexico, Missouri](https://images.trvl-media.com/place/8832/e1361911-161d-4582-a125-73ebc2a9a18c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/8832/e1361911-161d-4582-a125-73ebc2a9a18c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Mexico Luxury Hotels

Tonight

[Mar 19 - Mar 20](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2026-03-19&endDate=2026-03-20&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Mar 20 - Mar 21](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2026-03-20&endDate=2026-03-21&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2026-03-20&endDate=2026-03-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2026-03-27&endDate=2026-03-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Mexico luxury hotels

![Room, 1 King Bed, Accessible, Non Smoking (Mobility Accessible)](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/9d779a86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free toiletries, towels](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/24e32f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/fcdb510e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laundry room](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/4ac397d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Mexico

[](https://www.expedia.ca/Columbia-Hotels-Days-Inn-By-Wyndham-Mexico.h151247.Hotel-Information)

Mexico

7.0/10

Good

(298 reviews)

"Easy spot to stay for the night while passing through"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly

CA $111

CA $124 total

includes taxes & fees

Mar 23 - Mar 24

[](https://www.expedia.ca/Columbia-Hotels-Days-Inn-By-Wyndham-Mexico.h151247.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-02&endDate=2026-04-03&regionId=8832&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

## Find out more about Mexico

### Mexicoand its attractions for luxury travelers

In the charming town of Mexico, Missouri, luxury travellers can indulge in a variety of enriching experiences. Start your journey at the beautiful Audrain County Historical Society, where you can explore fascinating exhibits that showcase the region's rich heritage, all while enjoying a serene atmosphere. Nature enthusiasts will appreciate the stunning views at the nearby Mark Twain State Park, perfect for leisurely hikes and picnics amidst the picturesque landscapes. For a touch of elegance, treat yourself to a fine dining experience at one of the local upscale restaurants, where you can savour exquisite dishes crafted from fresh, local ingredients. If you're a golf aficionado, the Mexico Country Club offers a beautifully manicured course with stunning views, providing an excellent opportunity to unwind. After a day of exploration, consider staying at a luxurious hotel in the downtown area, where you can enjoy modern amenities and attentive service, ensuring a restful retreat. The combination of rich cultural experiences and comfortable accommodations makes Mexico, Missouri a hidden gem for the discerning traveller.

## Top Mexico Hotel Reviews

![Best Western Plus Columbia Inn](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/89f564da_y.jpg)

### Best Western Plus Columbia Inn

10/10 Excellent

"Room was spotless. Staff was friendly. Breakfast was great! "

[](https://expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information)

![Hampton Inn & Suites Columbia at University](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009513/2702d693_y.jpg)

### Hampton Inn & Suites Columbia at University

6/10 Okay

"Room was okay, The shower had no water pressure and the bed was hard as a rock. I also left a message for a wake up call, but never recieved the call. Food was edible but not much more than that. Honestly I felt like a was staying at a cheap motel instead of a better lodging option. Will not come back!!"

[](https://expedia.ca/Columbia-Hotels-Hampton-Inn-Suites-Columbia-At-University.h2009513.Hotel-Information)

![Ramada by Wyndham Columbia](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/2c2e5fb9_y.jpg)

### Ramada by Wyndham Columbia

10/10 Excellent

"Booked last minute, just passing through via work - traveling from Florida. The snow started falling about an hour before we got there and that super-hot jet tub was soooo nice! Breakfast was great too! Waffles, bagels, scrambled eggs, biscuits and gravy, etc Would absolutely stay here again!"

[](https://expedia.ca/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information)

![Quality Inn & Suites Columbia I-70](https://images.trvl-media.com/lodging/1000000/20000/14600/14520/e4003373_y.jpg)

### Quality Inn & Suites Columbia I-70

8/10 Good

"Room is nice and clean. Outside doesn't look impressive. "

[](https://expedia.ca/Columbia-Hotels-Quality-Inn-Suites-Columbia-I-70.h14520.Hotel-Information)

![Red Roof Inn Columbia, MO](https://images.trvl-media.com/lodging/1000000/20000/19600/19600/63579173_y.jpg)

### Red Roof Inn Columbia, MO

2/10 Terrible

"Shower curtain rod halfway off the wall on each end, the shower didn't work, everything was dirty, including the "clean towels". Holes in walls. Tv did not work. Telephone wasn't even hooked up."

[](https://expedia.ca/Columbia-Hotels-Red-Roof-Inn-Columbia.h19600.Hotel-Information)

![voco The Tiger Hotel Columbia, MO by IHG](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/17a25a6c_y.jpg)

### voco The Tiger Hotel Columbia, MO by IHG

10/10 Excellent

"Everything was great "

[](https://expedia.ca/Columbia-Hotels-The-Tiger-Hotel.h4790037.Hotel-Information)

![Days Inn by Wyndham Mexico](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/9d779a86_y.jpg)

### Days Inn by Wyndham Mexico

8/10 Good

"None"

[](https://expedia.ca/Columbia-Hotels-Days-Inn-By-Wyndham-Mexico.h151247.Hotel-Information)

## Frequently asked questions

### Which area of Mexico is best to stay in for luxury hotels?

> This area is the heart of Mexico, Missouri, offering the most upscale accommodation options. It's well-connected and provides easy access to the town's amenities. You'll find the highest concentration of quality hotels here, often featuring amenities like high-end fitness equipment, indoor pools, and spacious rooms.
> 
>   
> Couples looking for a comfortable and convenient stay will find this area ideal. It's close to local dining options and provides a good base for exploring the town, such as visiting the Audrain County Historical Society or enjoying a stroll in the nearby parks.

### How much does a luxury hotel in Mexico cost?

### What luxury activities and experiences are there in Mexico?

> This area offers a good balance of convenience and access to local amenities. You'll find a selection of local eateries, a few shops, and the city's historical sites within easy reach. The layout is quite straightforward, making it simple to navigate on foot or by car.
> 
>   
> For couples looking for a relaxed getaway, staying near the town centre provides easy access to the local parks and the historic sites. You can enjoy a leisurely stroll through the city or visit the Audrain County Historical Society.
> 
>   
> Solo travellers will also find the town centre convenient.

### How can I save on a luxury hotel in Mexico with Expedia?

### Is it cheaper to book a luxury Mexico hotel and flights as a package?

### Can I cancel my luxury hotel reservation on Expedia?

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