Title: Mesopotamia Vacation Home Rentals from CA $258: Search Top Private Vacation Homes for Rent | Expedia.ca [Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d3000453277.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d3000453277.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d3000453277.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d3000453277.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d3000453277.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jun 26 - Jun 28](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesopotamia vacation homes ![Exterior](https://images.trvl-media.com/lodging/34000000/33560000/33559900/33559811/07c3473f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33560000/33559900/33559811/098bba7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33560000/33559900/33559811/9b6badc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/34000000/33560000/33559900/33559811/ea66d4ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Middlefield [](https://www.expedia.ca/Mesopotamia-Hotels-Little-House-On-The-Farm.h33559811.Hotel-Information) 10/10 Exceptional (94 reviews) "My stay here was wonderful! James and Anna were very welcoming and such a clean place when arriving! I love this area as I grew up here and was close to many destinations I had planned. I will definitely be returning again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah S. CA $211 CA $311 total includes taxes & fees Mar 6 - Mar 7 [](https://www.expedia.ca/Mesopotamia-Hotels-Little-House-On-The-Farm.h33559811.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/121000000/120880000/120874300/120874245/12776e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120880000/120874300/120874245/bc103277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120880000/120874300/120874245/64830e66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120880000/120874300/120874245/784f034a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Warren [](https://www.expedia.ca/Warren-Hotels-Welcoming-3-Bedroom-House-Howland-OH.h120874245.Hotel-Information) 8.0/10 Very good (4 reviews) "Great hosts and location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isadora N. CA $125 CA $258 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Warren-Hotels-Welcoming-3-Bedroom-House-Howland-OH.h120874245.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/75000000/74300000/74297700/74297698/efafd899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74300000/74297700/74297698/fd533295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/75000000/74300000/74297700/74297698/a4a8ea93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/75000000/74300000/74297700/74297698/345f6e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Chardon [](https://www.expedia.ca/Chardon-Hotels-The-Thistle-House-Off-Chardon-Square.h74297698.Hotel-Information) 10/10 Exceptional (46 reviews) "This is a charming home and had everything we needed. It is very well appointed, comfortable and a wonderful place to return to." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $420 CA $672 total includes taxes & fees Mar 4 - Mar 5 [](https://www.expedia.ca/Chardon-Hotels-The-Thistle-House-Off-Chardon-Square.h74297698.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/119000000/118330000/118322300/118322219/53364eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118330000/118322300/118322219/0d3b0432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/119000000/118330000/118322300/118322219/f7782180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/119000000/118330000/118322300/118322219/011ba866.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Mantua [](https://www.expedia.ca/Mantua-Hotels-Peaceful-Pioneer-Place-On-Our-Family-Farm-In-Mantua.h118322219.Hotel-Information) 9.6/10 Exceptional (5 reviews) "We had a great time!! The home has a beautiful lay out and we were very comfortable!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pamela M. CA $314 CA $589 total includes taxes & fees Mar 4 - Mar 5 [](https://www.expedia.ca/Mantua-Hotels-Peaceful-Pioneer-Place-On-Our-Family-Farm-In-Mantua.h118322219.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/111000000/110980000/110972100/110972095/w1598h1193x0y4-29dccf82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110980000/110972100/110972095/w1582h1041x0y6-36c81883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/111000000/110980000/110972100/110972095/w1600h719x0y7-23e054cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/111000000/110980000/110972100/110972095/w1596h716x0y0-cdb28df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Garrettsville [](https://www.expedia.ca/Garrettsville-Hotels-Lovely-Private-3-Bedroom-House-Nestled-In-The-Hiram-Countryside.h110972095.Hotel-Information) 9.0/10 Wonderful (9 reviews) "Very nice property. Clean, great kitchen, beautiful property in the woods. Would definitely come here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roger B. CA $252 CA $478 total includes taxes & fees Mar 5 - Mar 6 [](https://www.expedia.ca/Garrettsville-Hotels-Lovely-Private-3-Bedroom-House-Nestled-In-The-Hiram-Countryside.h110972095.Hotel-Information) ![Smart TV, offices](https://images.trvl-media.com/lodging/96000000/96000000/95991700/95991663/f65c991b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, offices](https://images.trvl-media.com/lodging/96000000/96000000/95991700/95991663/50a94b1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/96000000/95991700/95991663/8bc20b87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/96000000/96000000/95991700/95991663/dcd82430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Garrettsville [](https://www.expedia.ca/Garrettsville-Hotels-Small-Town-Vibes-In-Garrettsville.h95991663.Hotel-Information) 10/10 Exceptional (3 reviews) "Very clean, solid rental. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher P. CA $353 CA $533 total includes taxes & fees Mar 5 - Mar 6 [](https://www.expedia.ca/Garrettsville-Hotels-Small-Town-Vibes-In-Garrettsville.h95991663.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-17&endDate=2026-03-18®ionId=3000453277&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AA_SPRING_PROMO_3000453277) ## Find vacation rentals that suit your style Apartments [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Ohio%2C+United+States+of+America®ionId=3000453277&latLong=41.458389%2C-80.955092&adults=2&startDate=2026-06-01&d1=2026-06-01&endDate=2026-06-04&d2=2026-06-04&lodging=APARTMENT) Cabins [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Ohio%2C+United+States+of+America®ionId=3000453277&latLong=41.458389%2C-80.955092&adults=2&startDate=2026-06-01&d1=2026-06-01&endDate=2026-06-04&d2=2026-06-04&lodging=CABIN) Villas [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Ohio%2C+United+States+of+America®ionId=3000453277&latLong=41.458389%2C-80.955092&adults=2&startDate=2026-06-01&d1=2026-06-01&endDate=2026-06-04&d2=2026-06-04&lodging=VILLA) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Ohio%2C+United+States+of+America®ionId=3000453277&latLong=41.458389%2C-80.955092&adults=2&startDate=2026-06-01&d1=2026-06-01&endDate=2026-06-04&d2=2026-06-04&lodging=VACATION_HOME) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Ohio%2C+United+States+of+America®ionId=3000453277&latLong=41.458389%2C-80.955092&adults=2&startDate=2026-06-01&d1=2026-06-01&endDate=2026-06-04&d2=2026-06-04&lodging=COTTAGE) Chalets [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Ohio%2C+United+States+of+America®ionId=3000453277&latLong=41.458389%2C-80.955092&adults=2&startDate=2026-06-01&d1=2026-06-01&endDate=2026-06-04&d2=2026-06-04&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Private-Vacation-Homes.d3000453277-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Private-Vacation-Homes.d3000453277-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Mesopotamia Hotel Reviews ![Log Home, Pvt Pond-Swim, Hot Tub](https://images.trvl-media.com/lodging/114000000/113220000/113215000/113214960/9161e6ee_y.jpg) ### Log Home, Pvt Pond-Swim, Hot Tub 10/10 Excellent "We have rented a lot of places for our large group of friends but I can say, without a doubt, that this was our favorite place by far. Can’t say enough about how pristinely clean, well stocked and fun Winding Wood cabin was. We’ve already rented it again for next year. From the large kitchen/dining room area, the coffee bar/room, the game room, the theater room and the bedrooms with extremely comfortable mattresses, you can’t go wrong staying here. There’s even a large hot tub that was used during the dead of winter. Had a couple of questions for the owners which were promptly addressed. You won’t be disappointed if you decide to stay here. We sure weren’t. Thanks Lisa and Rich for a wonderful stay!" [](https://expedia.ca/Hiram-Hotels-Log-Home.h113214960.Hotel-Information) ![Forever spring cabin](https://images.trvl-media.com/lodging/24000000/23300000/23299800/23299773/2eb85fc4_y.jpg) ### Forever spring cabin 10/10 Excellent "Beautiful cabin, quiet relaxing stay. Easy and quick response from owners. Highly recommend and will stay again! Thank you! " [](https://expedia.ca/Mesopotamia-Hotels-Forever-Spring-Cabin.h23299773.Hotel-Information) ![Charming Woodside Cabin w/ Private Hot Tub & Scenic Trails at Standing Rock Far](https://images.trvl-media.com/lodging/121000000/120050000/120044900/120044866/2705e0c6_y.jpg) ### Charming Woodside Cabin w/ Private Hot Tub & Scenic Trails at Standing Rock Far 10/10 Excellent "The unit was clean and cozy. A perfect little getaway. " [](https://expedia.ca/Madison-Hotels-Charming-Woodside-Cabin-W-Private-Hot-Tub-Scenic-Trails-At-Standing-Rock-Far.h120044866.Hotel-Information) ![Best Western Park Hotel](https://images.trvl-media.com/lodging/1000000/10000/3100/3047/97f494c2_y.jpg) ### Best Western Park Hotel 10/10 Excellent "The room was clean and generally functional. Breakfast was decent but not great." [](https://expedia.ca/Youngstown-Hotels-Best-Western-Park-Hotel.h3047.Hotel-Information) ![Stay in our cozy Maple Syrup Sugarhouse at Butternut Maple Farm](https://images.trvl-media.com/lodging/104000000/103620000/103612000/103611952/6a44d930_y.jpg) ### Stay in our cozy Maple Syrup Sugarhouse at Butternut Maple Farm 10/10 Excellent "We loved this little place. " [](https://expedia.ca/Stay-In-Our-Cozy-Maple-Syrup-Sugarhouse-At-Butternut-Maple-Farm.h103611952.Hotel-Information) ![Lakefront Haven w/ 50-ft Dock 4BR Near Punderson Park & Amish Country EV Charger](https://images.trvl-media.com/lodging/123000000/122740000/122733100/122733030/4fe012fe_y.jpg) ### Lakefront Haven w/ 50-ft Dock 4BR Near Punderson Park & Amish Country EV Charger 10/10 Excellent "By far the most pleasant and responsive host I have encountered in the dozen or so VRBOs I have stayed at. Keep it up! It's an older, refurbished home which had a few issues which were quickly addressed. I would stay there again. " [](https://expedia.ca/Newbury-Hotels-Lakefront-Haven-W-50-Ft-Dock-4BR-Near-Punderson-Park-Amish-Country-EV-Charger.h122733030.Hotel-Information) ![Country Cottage Farm Stay at Stoneycreek Acres](https://images.trvl-media.com/lodging/19000000/18980000/18970400/18970330/07cd0af1_y.jpg) ### Country Cottage Farm Stay at Stoneycreek Acres 10/10 Excellent "Great time. Molly and family were great." [](https://expedia.ca/Newbury-Hotels-Country-Cottage-Farm-Stay-At-Stoneycreek-Acres.h18970330.Hotel-Information) ![3-bedroom cabin in country setting with AC, WiFi, 15-20 min. to local wineries.](https://images.trvl-media.com/lodging/115000000/114880000/114878800/114878776/1a222835_y.jpg) ### 3-bedroom cabin in country setting with AC, WiFi, 15-20 min. to local wineries. 10/10 Excellent "The cabin is cozy, warm and inviting! It was a great place to stay and recharge! It is very clean and beautifully decorated!" [](https://expedia.ca/3-Bedroom-Cabin-In-Country-Setting-With-AC.h114878776.Hotel-Information) ![The Wildflower - Private cabin in wooded setting](https://images.trvl-media.com/lodging/89000000/88400000/88399500/88399409/cc7f5ca7_y.jpg) ### The Wildflower - Private cabin in wooded setting 10/10 Excellent "Very nice cabin. Clean. We had a little trouble with the tv but we are not tech savvy. " [](https://expedia.ca/Mesopotamia-Hotels-The-Wildflower-Private-Cabin-In-Wooded-Setting.h88399409.Hotel-Information) ## Find out more about Mesopotamia ## Mesopotamia Vacation Homes information | Number of reviews | 156 | | ----------------- | ----------------- | | Accommodation | 47 Vacation Homes | | Lowest Price | CA $258 | | Highest Price | CA $672 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [4 Star Hotels in Middlefield ](https://www.expedia.ca/4Star-Middlefield-Hotels.s40-0-d553248634983583868.Travel-Guide-Filter-Hotels) - [Hotels near Alpine Valley ](https://www.expedia.ca/Alpine-Valley-Hotels.0-l553248621561735299-0.Travel-Guide-Filter-Hotels) - [Aquilla Hotels ](https://www.expedia.ca/Aquilla-Hotels.d553248634983297386.Travel-Guide-Hotels) - [B&B in Burton ](https://www.expedia.ca/Burton-Bed-And-Breakfast.d6341720-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Burton ](https://www.expedia.ca/Burton-Guest-Houses.d6341720-aaGuestHouses.Travel-Guide-Accommodation) - 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