Title: Book the Best Mesopotamia LUXURY Hotels - Upscale Hotels in Mesopotamia | Expedia.ca [Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides) ![Mesopotamia which includes forests](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/196000/196542-Mesopotamia.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Mesopotamia ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mesopotamia Luxury Hotels Tonight [Sep 21 - Sep 22](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-21&endDate=2025-09-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 22 - Sep 23](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-22&endDate=2025-09-23&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-26&endDate=2025-09-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mesopotamia Luxury Hotels ## Our top choices for Mesopotamia luxury hotels ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/7373d519.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Terrace](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/56e76a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite (Cataratas)](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/704bf94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/895a3add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel das Cataratas, A Belmond Hotel, Iguassu Falls Foz do Iguaçu 9.8/10 Exceptional (1006) "great breakfast and pool area" CA $958 CA $1,109 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information) ![Indoor pool, 3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/afaaa032.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast, lunch, and dinner](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/f1f7c578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/ecef832c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/680b507f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Iguazu Grand Resort Spa & Casino Puerto Iguazú 9.0/10 Wonderful (560) "Nice hotel nice staff and excellent for the money " CA $416 CA $416 total Sep 22 - Sep 23 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-Iguazu-Grand-Resort-Spa-Casino.h979370.Hotel-Information) ![2 outdoor pools, open 9:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/2ab2ddf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/756174db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/bc2da393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/d4717a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gran Melia Iguazú Puerto Iguazú 9.2/10 Wonderful (1004) "Great hotel!" CA $800 CA $800 total Sep 22 - Sep 23 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-Gran-Melia-Iguazu.h454059.Hotel-Information) ![2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/f6b00076.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | Living area](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/19c30028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/f319948a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/32c235b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loi Suites Iguazú Hotel Puerto Iguazú 9.2/10 Wonderful (1001) "Everything at Lois Suites was excellent, especially staff!!!" CA $440 CA $440 total Sep 22 - Sep 23 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-Loi-Suites-Iguazu-Hotel.h2450070.Hotel-Information) ![1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/82a469cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/899bc322.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/w1600h893x0y175-428a2ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/2e24b1c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Reserva Virgin Lodge Puerto Iguazú 8.4/10 Very good (793) "Great place to stay " CA $131 CA $131 total Sep 28 - Sep 29 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-La-Cantera-Lodge-De-Selva-By-DON.h3020960.Hotel-Information) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/260f31f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub, steam room, body treatments, body scrubs, facials](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/660d3f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/b63c0178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/acc4e956.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Saint George Puerto Iguazú 8.8/10 Excellent (1005) "I appreciated that they held my luggage after I checked out and provided me a place to change clothes after my day at the Falls. They were also very nice about arranging a taxi to the airport." CA $157 CA $157 total Sep 22 - Sep 23 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-Hotel-Saint-George.h3281425.Hotel-Information) ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/6394d862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/dff6a08a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/3e2fe331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/5439a1a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Panoramic Grand Puerto Iguazú 8.6/10 Excellent (623) "AWESOME EXPERIENCE!!" CA $365 CA $365 total Sep 22 - Sep 23 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-Panoramic-Grand.h1829043.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/ab7cf242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/c8e2d18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/01e96b7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/544e495f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marcopolo Suites Iguazu Puerto Iguazú 6.6/10 (321) "Clean, and close to the center of the city." CA $104 CA $104 total Sep 22 - Sep 23 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-Marcopolo-Suites-Iguazu.h4041467.Hotel-Information) ![Outdoor pool, open 9 AM to 7 PM, sun loungers](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/298f1619.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/714d6028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | View from room](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/06851dcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served, Argentinean cuisine, pool views ](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/5d6cd34f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Hotel Delafonte Puerto Iguazú 8.6/10 Excellent (364) "Great location, good restaurant, nice pools, very responsive staff." [](https://www.expedia.ca/Puerto-Iguazu-Hotels-Boutique-Hotel-De-La-Fonte.h3469387.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/1b8fea71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/12e6da34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/587c4eb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Ñande Roga)](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/85070960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Aldea de la Selva Lodge Puerto Iguazú 8.8/10 Excellent (484) "We loved our stay. The Aldea went beyond our expectations! We highly recommend!" CA $123 CA $123 total Oct 8 - Oct 9 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-La-Aldea-De-La-Selva-Lodge.h3234974.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-05&endDate=2025-10-06®ionId=6208836&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Mesopotamia Hotel Reviews ## Explore a world of travel with Expedia - More ways to book - [Book Luxury Hotels in Mesopotamia on Expedia.com.ar](https://www.expedia.com.ar/Mesopotamia-Hoteles-Hotel-De-Lujo.0-0-d6208836-tHoteldelujo.Guia-filtrada-de-Hoteles)