Title: Book the Best BOUTIQUE Hotels in Mesopotamia in 2025 | Expedia.ca [Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides) ![Mesopotamia which includes forests](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/196000/196542-Mesopotamia.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Boutique Hotels in Mesopotamia from CA $139 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mesopotamia Boutique Hotels Tonight [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-30&endDate=2025-10-01&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-01&endDate=2025-10-02&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mesopotamia Boutique Hotels ![1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/82a469cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/3fdaf0a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/899bc322.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/w1600h893x0y175-428a2ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Reserva Virgin Lodge Puerto Iguazú 8.4/10 Very good (794) "Great place to stay " CA $150 CA $156 total Oct 1 - Oct 2 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-La-Cantera-Lodge-De-Selva-By-DON.h3020960.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c114ee3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c058d200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c58abaf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/ce029153.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Alondra Casa De Huéspedes Corrientes 9.2/10 Wonderful (65) CA $172 CA $172 total Oct 16 - Oct 17 [](https://www.expedia.ca/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/7373d519.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/895a3add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Terrace](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/d7a9171c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Terrace](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/56e76a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel das Cataratas, A Belmond Hotel, Iguassu Falls Foz do Iguaçu 9.8/10 Exceptional (1016) "great breakfast and pool area" CA $1,064 CA $1,231 total includes taxes & fees Oct 3 - Oct 4 [](https://www.expedia.ca/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information) ![2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/f6b00076.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/f319948a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/32c235b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/434e4bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loi Suites Iguazú Hotel Puerto Iguazú 9.2/10 Wonderful (1002) "We liked the jungle surroundings and the swimming pools" CA $444 CA $453 total Oct 1 - Oct 2 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-Loi-Suites-Iguazu-Hotel.h2450070.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2300000/2293100/2293030/04d72c9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2300000/2293100/2293030/a17cc0bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Winery](https://images.trvl-media.com/lodging/3000000/2300000/2293100/2293030/983b9770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 2 Single Beds](https://images.trvl-media.com/lodging/3000000/2300000/2293100/2293030/5339b4fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Posada Puerto Bemberg Puerto Libertad 9.8/10 Exceptional (15) CA $134 CA $139 total Oct 1 - Oct 2 [](https://www.expedia.ca/Puerto-Iguazu-Hotels-CASA-BEMBERG.h2293030.Hotel-Information) ![Outdoor pool, open 9 AM to 7 PM, sun loungers](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/298f1619.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served, Argentinean cuisine, pool views ](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/5d6cd34f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/863c7686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | View from room](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/06851dcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Hotel Delafonte Puerto Iguazú 8.6/10 Excellent (364) "Great location, good restaurant, nice pools, very responsive staff." [](https://www.expedia.ca/Puerto-Iguazu-Hotels-Boutique-Hotel-De-La-Fonte.h3469387.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-14&endDate=2025-10-15®ionId=6208836&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Mesopotamia Hotel Reviews ## Explore a world of travel with Expedia - More ways to book - [Book Boutique Hotels in Mesopotamia on Expedia.com.ar](https://www.expedia.com.ar/Mesopotamia-Hoteles-Hoteles-Boutique.0-0-d6208836-tHotelesboutique.Guia-filtrada-de-Hoteles)