Title: Hotels by Independent in Melrose from CA $201 | Expedia.ca [Melrose Travel Guide](https://expedia.ca/Melrose.dx553248635975870440)[Hotels in Melrose](https://expedia.ca/Melrose-Hotels.d553248635975870440.Travel-Guide-Hotels)[Vacation Rentals in Melrose](https://expedia.ca/Melrose-Vacation-Rentals.d553248635975870440.Travel-Guide-VacationRentals)[Flights to Melrose](https://expedia.ca/Cheap-Flights-To-Melrose.d553248635975870440.Travel-Guide-Flights)[Melrose Car Rentals](https://expedia.ca/Car-Rentals-In-Melrose.d553248635975870440.Car-Rental-Guide)[Melrose Vacation Packages](https://expedia.ca/Melrose.d553248635975870440.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Independent in Melrose from CA $201 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=553248635975870440&startDate=2025-10-22&endDate=2025-10-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=553248635975870440&startDate=2025-10-23&endDate=2025-10-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975870440&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975870440&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Melrose Independent Hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/18000000/17520000/17516100/17516018/13ad48d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/18000000/17520000/17516100/17516018/58f39ef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, Ensuite (Lily)](https://images.trvl-media.com/lodging/18000000/17520000/17516100/17516018/bedf7f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/18000000/17520000/17516100/17516018/ced98983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sweet Cane Inn Downtown Natchitoches 9.6/10 Exceptional (500) "This Bed and Breakfast was so nice and you could feel the history of Natchitoches Cane River all around! I definitely recommend for festival stays!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LaShawn CA $181 CA $201 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Natchitoches-Hotels-Sweet-Cane-Inn.h17516018.Hotel-Information) ![Executive Suite, 2 Bedrooms](https://images.trvl-media.com/lodging/91000000/90330000/90324200/90324108/b4c7a3f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 2 Bedrooms](https://images.trvl-media.com/lodging/91000000/90330000/90324200/90324108/3dc7a6fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/91000000/90330000/90324200/90324108/588f2472.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/91000000/90330000/90324200/90324108/1e980f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Opus House Natchitoches 10/10 Exceptional (14) "Excellent room and location to downtown Natchitoches" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah CA $301 CA $333 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Natchitoches-Hotels-Opus-House.h90324108.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/90000000/89540000/89533300/89533225/236ecebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89540000/89533300/89533225/f8ec529c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/90000000/89540000/89533300/89533225/785f8d30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/90000000/89540000/89533300/89533225/9ce6bf93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### "Clementine at The 403" Historic District Apartment Walkable to Downtown Natchitoches 10/10 Exceptional (21) "Loved my stay. would recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James [](https://www.expedia.ca/Natchitoches-Hotels-Clementine-At-The-403-Historic-District-Apartment-Walkable-To-Downtown.h89533225.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87430000/87429800/87429792/06bf0040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87430000/87429800/87429792/f2407b8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/88000000/87430000/87429800/87429792/f6a41692.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/88000000/87430000/87429800/87429792/218ccef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy, comfortable home overlooking Cane River -15 min from downtown Natchitoches Natchitoches 10/10 Exceptional (34) "Cute property on the Cane river. We really enjoyed our stay. Wish we could have stayed longer!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan W. [](https://www.expedia.ca/Natchitoches-Hotels-Cozy.h87429792.Hotel-Information) ![TV, fireplace](https://images.trvl-media.com/lodging/99000000/98230000/98225700/98225682/64e0ec0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/99000000/98230000/98225700/98225682/29638b16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/99000000/98230000/98225700/98225682/7ab9b8eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/99000000/98230000/98225700/98225682/f728926d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtown Riverside Oasis: Deck, Hot Tub & More! Natchitoches 10/10 Exceptional (31) "Beautiful house, great locstion and fun place to visit." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn W. [](https://www.expedia.ca/Natchitoches-Hotels-Downtown-Riverside-Oasis-Deck.h98225682.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/91000000/90350000/90346400/90346341/0be30fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90350000/90346400/90346341/9f054994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/91000000/90350000/90346400/90346341/30d9f841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90350000/90346400/90346341/0773b9e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cane River View 3BR Mid Century Modern Townhome Natchitoches 10/10 Exceptional (28) "Nice and clean and beds were comfortable!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tara R. [](https://www.expedia.ca/Natchitoches-Hotels-Cane-River-View-3BR-Mid-Century-Modern-Townhome.h90346341.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96090000/96085600/96085589/419ca68e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96090000/96085600/96085589/388e2568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96090000/96085600/96085589/ade90f29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/97000000/96090000/96085600/96085589/3245e5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home Away from Home Natchez 10/10 Exceptional (7) "Very pleased with this home. Spacious and probably the most well stocked home we have stayed in. Will definitely stay here again if ever back in this area! The owner had it decorated for Christmas which was lovely. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa F. [](https://www.expedia.ca/Natchez-Hotels-Home-Away-From-Home.h96085589.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/122000000/121230000/121225500/121225485/448fbf1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/122000000/121230000/121225500/121225485/32cb2ab5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/122000000/121230000/121225500/121225485/f4ccd3bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/122000000/121230000/121225500/121225485/6a3fb6cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3BR Downtown Natchitoches Home, 1.5 Bath, Walking Distance to Front St Natchitoches [](https://www.expedia.ca/Natchitoches-Hotels-Charming-3BR-Downtown-Natchitoches-Home.h121225485.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/34000000/33510000/33509600/33509507/3c3eb9f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi](https://images.trvl-media.com/lodging/34000000/33510000/33509600/33509507/bb356acd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33510000/33509600/33509507/f0904bfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/34000000/33510000/33509600/33509507/c47c22d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy cabins on 30 acres...perfect for families. Natchitoches 9.8/10 Exceptional (107) "The cabin was great, clean, and cozy. We were able to explore the grounds and stay out of each other's way. It was a great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cole H. [](https://www.expedia.ca/Natchitoches-Hotels-Cozy-Cabins-On-30-Acresperfect-For-Families.h33509507.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/75000000/74300000/74298000/74297960/c7f99907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/75000000/74300000/74298000/74297960/5071881d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/75000000/74300000/74298000/74297960/144c7ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74300000/74298000/74297960/b4c30a4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax, Enjoy, Explore, On Cane! Natchez 9.2/10 Wonderful (15) "Comfortable home and not to far from town! We loved it will definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis M. [](https://www.expedia.ca/Natchez-Hotels-Relax.h74297960.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-05&endDate=2025-11-06®ionId=553248635975870440&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMelrose-Hotels-Independent.0-0-d553248635975870440--bIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMelrose-Hotels-Independent.0-0-d553248635975870440--bIndependent.Travel-Guide-Filter-Hotels) ## Top Melrose Hotel Reviews ![Fairfield Inn & Suites Natchitoches](//images.trvl-media.com/lodging/7000000/6370000/6368900/6368874/bb3432ec_y.jpg) ### Fairfield Inn & Suites Natchitoches 10/10 Excellent "The breakfast was fresh and the room was clean. " [](https://expedia.ca/Natchitoches-Hotels-Fairfield-Inn-Suites-Natchitoches.h6368874.Hotel-Information) ![Comfort Suites Natchitoches](//images.trvl-media.com/lodging/4000000/3950000/3946500/3946402/eda35d31_y.jpg) ### Comfort Suites Natchitoches 10/10 Excellent "Clean room great staff good breakfast " [](https://expedia.ca/Natchitoches-Hotels-Comfort-Suites.h3946402.Hotel-Information) ![Opus House ](//images.trvl-media.com/lodging/91000000/90330000/90324200/90324108/b4c7a3f2_y.jpg) ### Opus House 10/10 Excellent "Cole and Denise extended the warmest hospitality. The Opus House is beautiful and comfortable." [](https://expedia.ca/Natchitoches-Hotels-Opus-House.h90324108.Hotel-Information) ![Church Street Inn](//images.trvl-media.com/lodging/16000000/15260000/15250800/15250740/3cf9e7be_y.jpg) ### Church Street Inn 10/10 Excellent "Wonderful staff, good breakfast, nice location overall wonderful!" [](https://expedia.ca/Natchitoches-Hotels-Church-Street-Inn.h15250740.Hotel-Information) ![Sweet Cane Inn](//images.trvl-media.com/lodging/18000000/17520000/17516100/17516018/13ad48d1_y.jpg) ### Sweet Cane Inn 10/10 Excellent "Sweet Cane B&B was phenomenal. Our first stay at a B&B and we loved it. Tiffanie our morning breakfast host out did her self. Breakfast was delicious. Definitely will be back " [](https://expedia.ca/Natchitoches-Hotels-Sweet-Cane-Inn.h17516018.Hotel-Information) ![Best Western Natchitoches Inn](//images.trvl-media.com/lodging/3000000/2760000/2751300/2751285/d4ea0c0b_y.jpg) ### Best Western Natchitoches Inn 10/10 Excellent "This probably the nicest hotel at this price range I remember staying in. Be sure to check out the French Market Express next door if you stay here... full of pleasant surprises!" [](https://expedia.ca/Natchitoches-Hotels-Best-Western-Natchitoches-Inn.h2751285.Hotel-Information) ![Hampton Inn Natchitoches](//images.trvl-media.com/lodging/1000000/330000/328200/328177/5604f04f_y.jpg) ### Hampton Inn Natchitoches 10/10 Excellent "The staff were very friendly and helpful. The young lady that checked us in was a delight. The room was clean and comfortable. The bathroom was perfect. We enjoyed the stay." [](https://expedia.ca/Natchitoches-Hotels-Hampton-Inn-Natchitoches.h328177.Hotel-Information) ![Holiday Inn Express Hotel & Suites Natchitoches by IHG](//images.trvl-media.com/lodging/1000000/220000/213300/213267/64c066c5_y.jpg) ### Holiday Inn Express Hotel & Suites Natchitoches by IHG 10/10 Excellent "Great stay as always " [](https://expedia.ca/Natchitoches-Hotels-Holiday-Inn-Express-Hotel-Suites-Natchitoches.h213267.Hotel-Information) ![Super 8 by Wyndham Natchitoches](//images.trvl-media.com/lodging/1000000/460000/459900/459891/1f54e2bf_y.jpg) ### Super 8 by Wyndham Natchitoches 10/10 Excellent "I liked my staff. Very nice. Didnt like dirty carpets. 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