Title: Hotels by Lopesan Hotels & Resorts in Mediterranean Region | Expedia.ca [Mediterranean Region Travel Guide](https://expedia.ca/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Vacation Rentals in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Vacation-Rentals.d844522342175883264.Travel-Guide-VacationRentals)[Flights to Mediterranean Region](https://expedia.ca/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Rentals](https://expedia.ca/Car-Rentals-In-Mediterranean-Region.d844522342175883264.Car-Rental-Guide)[Mediterranean Region Vacation Packages](https://expedia.ca/Mediterranean-Region.d844522342175883264.Destination-Travel-Guides) ![Basilica de Santa Maria del Mar showing a church or cathedral and heritage architecture](https://images.trvl-media.com/place/6066991/c3c69d6e-c998-4f36-ad18-3e65173208c0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Lopesan Hotels & Resorts in Mediterranean Region - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 1 - Jan 2](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2026-01-01&endDate=2026-01-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 2 - Jan 3](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2026-01-02&endDate=2026-01-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Lopesan-Hotels-Resorts.0-0-d844522342175883264--bLopesanHotelsResorts.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Lopesan-Hotels-Resorts.0-0-d844522342175883264--bLopesanHotelsResorts.Travel-Guide-Filter-Hotels) ## Top Mediterranean Region Hotel Reviews ![Hotel Riu Plaza España](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f_y.jpg) ### Hotel Riu Plaza España 10/10 Excellent "Staff very courteous, room clean and quiet, rain shower is spectacular, and breakfast is delicious (one of the best I ever had). My only suggestion for future guests is not to rent a car if you’re going to visit Madrid. The streets are not easy to drive, you can end up with an accident or a fine and in this hotel the parking is very, very small, not suitable for vans or SUV’s." [](https://expedia.ca/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information) ![Hotel Acta Moa- New Opening](https://images.trvl-media.com/lodging/118000000/117140000/117137400/117137301/1fd8b13a_y.jpg) ### Hotel Acta Moa- New Opening 10/10 Excellent "New & very clean hotel" [](https://expedia.ca/Lisbon-District-Hotels-Acta-Moa.h117137301.Hotel-Information) ![Hotel Regina](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/e8709f28_y.jpg) ### Hotel Regina 10/10 Excellent "Wonderful staff, attention to details, nice modern designed rooms. Perfect location." [](https://expedia.ca/Madrid-Hotels-Hotel-Regina.h1170158.Hotel-Information) ![Hard Rock Hotel Madrid](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/f79da699_y.jpg) ### Hard Rock Hotel Madrid 10/10 Excellent "We enjoyed our stay. We were upsold a ‘city view’ room but basically that faced the street rather than the inner part of the hotel. Maybe suited for the summer but it wasn’t worth it for winter. The view from the 5th floor isn’t high enough to see the city. The room was spacious. The bathroom was pod style with separate bathroom and shower room with frosted glass as you enter. The hotel is located near Atocha train station and an easy journey to Toledo. " [](https://expedia.ca/Madrid-Hotels-Hard-Rock-Hotel-Madrid.h66906927.Hotel-Information) ![The Hive Hotel](https://images.trvl-media.com/lodging/25000000/24470000/24463300/24463268/ec6c185a_y.jpg) ### The Hive Hotel 10/10 Excellent "Everything was great. I requested to be in a higher floor and they moved us. Thank you The service when making up the room every day was awesome." [](https://expedia.ca/Rome-Hotels-The-Hive-Hotel.h24463268.Hotel-Information) ![Arc la Rambla](https://images.trvl-media.com/lodging/1000000/570000/560400/560394/057df268_y.jpg) ### Arc la Rambla 10/10 Excellent "Clean room very attentive staff and reception desk and close to major tourist sites." [](https://expedia.ca/Barcelona-Hotels-Arc-La-Rambla.h560394.Hotel-Information) ![Trastevere Roma | UNA Esperienze](https://images.trvl-media.com/lodging/75000000/74060000/74055900/74055827/0d267171_y.jpg) ### Trastevere Roma | UNA Esperienze 10/10 Excellent "The hotel is located in my favorite neighborhood in Rome. The staff was wonderful with the front desk assisting with restaurant reservations, and returning my daughter's Air pods, which she left behind. The hotel's rooftop restaurant was delicious! The baked goods at breakfast were good and the coffee was excellent, but I would prefer more egg options. Overall, highly recommend." [](https://expedia.ca/Rome-Hotels-UNAHOTELS-Trastevere-Roma.h74055827.Hotel-Information) ![Akra Antalya](https://images.trvl-media.com/lodging/1000000/30000/21700/21663/1add5596_y.jpg) ### Akra Antalya 10/10 Excellent "This is the best hotel in Antalya area. Rooms a spotless, very comfortable bed, breakfast buffet is very tasty and with good quality. Spa, indoor pool and gym area are very spacious and clean. Staff is also very helpful and kind. We really enjoyed our stay. " [](https://expedia.ca/Antalya-Hotels-Akra-Hotel.h21663.Hotel-Information) ![Hotel Dei Mellini](https://images.trvl-media.com/lodging/1000000/70000/63400/63399/db6d1bc9_y.jpg) ### Hotel Dei Mellini 10/10 Excellent "Great staffs and great room." [](https://expedia.ca/Rome-Hotels-Hotel-Dei-Mellini.h63399.Hotel-Information)