Title: Book the Best BUSINESS Hotels in Medicine Lake in 2026 | Expedia.ca [Vacation Rentals in Minneapolis - St. Paul](https://expedia.ca/Minneapolis-St-Paul-Vacation-Rentals.d178287.Travel-Guide-VacationRentals)[Flights to Minneapolis - St. Paul](https://expedia.ca/Cheap-Flights-To-Minneapolis-St-Paul.d178287.Travel-Guide-Flights)[Things to do in Minneapolis - St. Paul](https://expedia.ca/Things-To-Do-In-Minneapolis-St-Paul.d178287.Travel-Guide-Activities)[Medicine Lake Car Rentals](https://expedia.ca/Car-Rentals-In-Medicine-Lake.d553248634983312763.Car-Rental-Guide)[Medicine Lake Vacations](https://expedia.ca/Medicine-Lake.d553248634983312763.Destination-Travel-Guides) ![Backlit Evening Rain Shower over Medicine Lake in Plymouth, Minnesota](https://images.trvl-media.com/place/553248634983312763/47e1a07c-76cd-4220-8845-457c50647de9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Medicine Lake, MN from CA $77 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Medicine Lake Business Hotels Tonight [Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=553248634983312763&startDate=2025-12-28&endDate=2025-12-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 29 - Dec 30](https://www.expedia.ca/Hotel-Search?regionId=553248634983312763&startDate=2025-12-29&endDate=2025-12-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248634983312763&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248634983312763&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Medicine Lake business-friendly hotels ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/570000/565100/565006/6213d079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/565100/565006/5af56e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/565100/565006/2b2880c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/565100/565006/6a91b655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Mall of America - MSP Airport by IHG [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Holiday-Inn-Express-Suites-Mall-Of-America-MSP-Airport.h565006.Hotel-Information) East Bloomington 9.0/10 Wonderful (2889) "Great place to stay!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamera CA $115 CA $133 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Holiday-Inn-Express-Suites-Mall-Of-America-MSP-Airport.h565006.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/460000/455200/455156/6563eb7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/460000/455200/455156/8e4b5166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/455200/455156/8b3ef460.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/455200/455156/1c68c20e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Minneapolis Airport Mall of America [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Hilton-Garden-Inn-Minneapolis-Airport-Mall-Of-America.h455156.Hotel-Information) East Bloomington 8.4/10 Very good (2187) "Great staff great rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mathew CA $99 CA $115 total includes taxes & fees Jan 25 - Jan 26, 2026 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Hilton-Garden-Inn-Minneapolis-Airport-Mall-Of-America.h455156.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/2000000/1640000/1639800/1639753/0823a637.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1640000/1639800/1639753/e285a686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, City View](https://images.trvl-media.com/lodging/2000000/1640000/1639800/1639753/0d7a9d92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/2000000/1640000/1639800/1639753/58d3a670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Minneapolis [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-The-Westin-Minneapolis.h1639753.Hotel-Information) Downtown Minneapolis 8.4/10 Very good (1002) "Always a great stay at the Westin! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) gabby CA $149 CA $174 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-The-Westin-Minneapolis.h1639753.Hotel-Information) ![Frette Italian sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/910000/907700/907620/f3f7e514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/910000/907700/907620/79546183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/910000/907700/907620/19613a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Performer) | Living area](https://images.trvl-media.com/lodging/1000000/910000/907700/907620/a8fdbb0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lofton Hotel, Tapestry Collection by Hilton [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-The-Lofton-Hotel.h907620.Hotel-Information) Downtown Minneapolis 9.4/10 Exceptional (1001) "Friendly staff, comfortable beds, beautiful views, great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julia CA $157 CA $184 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-The-Lofton-Hotel.h907620.Hotel-Information) ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/5300/5289/808b3e2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5300/5289/ce232f9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/5300/5289/5f9c8ae7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5300/5289/ed73df6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marquette Hotel, Curio Collection by Hilton [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-The-Marquette-Hotel.h5289.Hotel-Information) Downtown Minneapolis 9.4/10 Exceptional (1004) "Clean, helpful staff and location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheena Martina CA $146 CA $171 total includes taxes & fees Jan 6 - Jan 7, 2026 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-The-Marquette-Hotel.h5289.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2360000/2351500/2351476/8bf1abd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2360000/2351500/2351476/2c428d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2360000/2351500/2351476/e1bdf41e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2360000/2351500/2351476/4176e409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Minneapolis Downtown [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Hilton-Garden-Inn-Minneapolis-Downtown.h2351476.Hotel-Information) Downtown Minneapolis 8.4/10 Very good (1005) "Everything was wonderful... just like the last time I stayed here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessie CA $125 CA $147 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Hilton-Garden-Inn-Minneapolis-Downtown.h2351476.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/13000000/12790000/12786200/12786116/cf932937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/13000000/12790000/12786200/12786116/c6118ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12790000/12786200/12786116/53752aae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/13000000/12790000/12786200/12786116/821144a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Bloomington - Minneapolis [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Hyatt-Regency-Bloomington-Minneapolis.h12786116.Hotel-Information) East Bloomington 9.0/10 Wonderful (2070) "Clean room, great breakfast, convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joanne CA $122 CA $142 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Hyatt-Regency-Bloomington-Minneapolis.h12786116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9760000/9758000/9757972/2e64134f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9760000/9758000/9757972/045789c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9760000/9758000/9757972/b9d0e6a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/10000000/9760000/9758000/9757972/7174dc85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Minneapolis / Downtown [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Hampton-Inn-Suites-Minneapolis-Downtown.h9757972.Hotel-Information) Downtown Minneapolis 9.4/10 Exceptional (1934) "Courteous staff and great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darren CA $104 CA $122 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Hampton-Inn-Suites-Minneapolis-Downtown.h9757972.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38700000/38696200/38696190/272b83fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/39000000/38700000/38696200/38696190/0d5850d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/39000000/38700000/38696200/38696190/75a519ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/39000000/38700000/38696200/38696190/5a2ecac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Minneapolis Shakopee [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Fairfield-Inn-Suites-By-Marriott-Minneapolis-Shakopee.h38696190.Hotel-Information) Shakopee 9.0/10 Wonderful (764) "The desk clerk was very friendly, polite and responsive. Love staying here." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Craig CA $116 CA $129 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Fairfield-Inn-Suites-By-Marriott-Minneapolis-Shakopee.h38696190.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/990000/987200/987158/ed0ebfbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/990000/987200/987158/f57517fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/987200/987158/dce13003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/990000/987200/987158/f56ea974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Prime Rate Inn [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Prime-Rate-Inn.h987158.Hotel-Information) Burnsville 8.0/10 Very good (1143) "Just now a great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy CA $69 CA $77 total includes taxes & fees Dec 31 - Jan 1, 2026 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Prime-Rate-Inn.h987158.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-11&endDate=2026-01-12®ionId=553248634983312763&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Medicine Lake Hotel Reviews ![The Marquette Hotel, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/5300/5289/808b3e2e_y.jpg) ### The Marquette Hotel, Curio Collection by Hilton 10/10 Excellent "Clean, helpful staff and location. " [](https://expedia.ca/Minneapolis-St-Paul-Hotels-The-Marquette-Hotel.h5289.Hotel-Information) ![Mystic Lake Casino Hotel](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/d6da8b6f_y.jpg) ### Mystic Lake Casino Hotel 10/10 Excellent "It was okay " [](https://expedia.ca/Minneapolis-St-Paul-Hotels-Mystic-Lake-Casino-Hotel.h198946.Hotel-Information) ![Embassy Suites by Hilton Minneapolis Airport](https://images.trvl-media.com/lodging/1000000/30000/28400/28360/c1fd6c36_y.jpg) ### Embassy Suites by Hilton Minneapolis Airport 10/10 Excellent "All good" [](https://expedia.ca/Minneapolis-St-Paul-Hotels-Embassy-Suites-By-Hilton-Minneapolis-Airport.h28360.Hotel-Information) ![Country Inn & Suites by Radisson, Bloomington at Mall of America, MN](https://images.trvl-media.com/lodging/1000000/10000/5600/5579/6c302e60_y.jpg) ### Country Inn & Suites by Radisson, Bloomington at Mall of America, MN 10/10 Excellent "Staff was great - especially enjoyed the guy from Mississippi. This kiddie toilet was very low and the water was too high in the toilet." [](https://expedia.ca/Minneapolis-St-Paul-Hotels-Country-Inn-Suites-By-Radisson.h5579.Hotel-Information) ![The Saint Paul Hotel](https://images.trvl-media.com/lodging/1000000/20000/19700/19645/8b7f1432_y.jpg) ### The Saint Paul Hotel 10/10 Excellent "Gentleman at the front dest was very pleasant and let us check in early since our room was ready" [](https://expedia.ca/Minneapolis-St-Paul-Hotels-The-Saint-Paul-Hotel.h19645.Hotel-Information) ![Hyatt Place Minneapolis Airport-South](https://images.trvl-media.com/lodging/1000000/70000/64100/64078/a1ecb3a3_y.jpg) ### Hyatt Place Minneapolis Airport-South 10/10 Excellent "Well run, friendly atmosphere." [](https://expedia.ca/Minneapolis-St-Paul-Hotels-Hyatt-Place-Minneapolis-Airport-South.h64078.Hotel-Information) ![Holiday Inn Express & Suites Mall of America - MSP Airport by IHG](https://images.trvl-media.com/lodging/1000000/570000/565100/565006/6213d079_y.jpg) ### Holiday Inn Express & Suites Mall of America - MSP Airport by IHG 10/10 Excellent "Beautiful rooms" [](https://expedia.ca/Minneapolis-St-Paul-Hotels-Holiday-Inn-Express-Suites-Mall-Of-America-MSP-Airport.h565006.Hotel-Information) ![Hyatt Place Minneapolis Downtown](https://images.trvl-media.com/lodging/7000000/6390000/6389400/6389369/869f4535_y.jpg) ### Hyatt Place Minneapolis Downtown 10/10 Excellent "excellent fast check in, room is great. Very nice hotel" [](https://expedia.ca/Minneapolis-St-Paul-Hotels-Hyatt-Place-Minneapolis-Downtown.h6389369.Hotel-Information) ![Radisson Blu Mall of America](https://images.trvl-media.com/lodging/6000000/5680000/5679900/5679898/0fe13c3a_y.jpg) ### Radisson Blu Mall of America 10/10 Excellent "Me and my family had the most amazing time the hotel is so nice decorated for Christmas it’s so clean the staff is so friendly it’s conveniently connected to the Mall Of America. The bed was super comfortable the food at the restaurant was delicious they also provided a shuttle to and from the airport. " [](https://expedia.ca/Minneapolis-St-Paul-Hotels-Radisson-Blu-Mall-Of-America.h5679898.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [B&B in Crystal ](https://www.expedia.ca/Crystal-Bed-And-Breakfast.d94228-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Castles in Crystal ](https://www.expedia.ca/Crystal-Castles.d94228-aaCastles.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Crystal ](https://www.expedia.ca/Crystal-Hotels-Beach-Hotel.0-0-d94228-tBeachHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Crystal ](https://www.expedia.ca/Crystal-Hotels-Cheap-Hotels.0-0-d94228-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Crystal ](https://www.expedia.ca/Crystal-Hotels-Hotels-With-Hot-Tubs.0-0-d94228-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Spa Hotels in Crystal ](https://www.expedia.ca/Crystal-Hotels-Spa-Hotel.0-0-d94228-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Crystal ](https://www.expedia.ca/Crystal-Hotels-Waterpark-Hotels.0-0-d94228-tWaterparkHotels.Travel-Guide-Filter-Hotels) - 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