Title: Book the Best Medical District FAMILY FRIENDLY Hotels from CA $102 - Kid-Friendly Hotels in Medical District, Greenville | Expedia.ca [Medical District Travel Guide](https://expedia.ca/Greenville-Medical-District.dx908649044914896896)[Vacation Rentals in Greenville](https://expedia.ca/Greenville-Vacation-Rentals.d2779.Travel-Guide-VacationRentals)[Flights to Greenville](https://expedia.ca/Cheap-Flights-To-Greenville.d2779.Travel-Guide-Flights)[Medical District Car Rentals](https://expedia.ca/Car-Rentals-In-Medical-District.d908649044914896896.Car-Rental-Guide)[Medical District Vacations](https://expedia.ca/Medical-District.d908649044914896896.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/family_friendly.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Family Hotels in Medical District, Greenville from CA $102 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Medical District Family Hotels Tonight [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-10-23&endDate=2025-10-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Tomorrow [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-10-24&endDate=2025-10-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) ## Top Medical District Family Hotels ![Reception](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/1f6092e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/2203e988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/b26d4f63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/2deb739b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Marriott Greenville Medical District 8.8/10 Excellent (874) "It was easy to access. Staff was friendly and accomodating. Room was clean and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy CA $178 CA $201 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-9ca87b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3840h2556x0y4-0c33f88e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2415x3y3-72322295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2560x3y0-dfdc5921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden INN Greenville University Uptown Greenville 9.4/10 Exceptional (83) "Excellent stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $178 CA $201 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Hilton-Garden-INN-Greenville-University.h108395066.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/d6fc4788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/af549a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/dbd945d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/941cb3a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Greenville near University Greenville 7.4/10 Good (1001) "Great staff, safe area, family friendly, thankful for the workout room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre CA $103 CA $117 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Quality-Inn-Greenville-Near-University.h13542.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/6d7fbebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/d37ee56a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/8d14df71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/f0182b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Greenville by IHG Greenville 8.8/10 Excellent (1000) "Property was nice and well kept. Breakfast was good though not a lot of choice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jamila CA $155 CA $175 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Greenville-Hotels-Holiday-Inn-Greenville.h12870.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/0f38728e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/15ae8005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/9dd3e245.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/5a87c84b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Greenville, NC Winterville 7.6/10 Good (802) "Had a good stay here " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jesse CA $127 CA $145 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Greenville-Hotels-Country-Inn-Suites-By-Radisson.h62311.Hotel-Information) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/101000000/100900000/100891800/100891787/fd63f0c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/101000000/100900000/100891800/100891787/c3900978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/101000000/100900000/100891800/100891787/bd923521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100900000/100891800/100891787/4afc87a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ECU Pirate Country Getaway! First-floor Master, extra room, and separate office! Greenville 10/10 Exceptional (15) "The property was very clean and well appointed. Location was perfect for what we needed!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller CA $176 CA $403 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Greenville-Hotels-ECU-Pirate-Country-Retreat-Master-On-1st-Floor.h100891787.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89720000/89719800/89719731/e23324c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89720000/89719800/89719731/af915b87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books, computer monitors](https://images.trvl-media.com/lodging/90000000/89720000/89719800/89719731/6b7f7978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/90000000/89720000/89719800/89719731/52507331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury 3BD/3BA Smart Home Near ECU with Fast WiFi & FREE EV Charging! Greenville 9.6/10 Exceptional (53) "The property was very clean and had all that you needed to enjoy our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Damien L. CA $160 CA $383 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Greenville-Hotels-Modern-3BD-3BA-Luxury-Retreat-Near-ECU-Smart-Home.h89719731.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/1600/1575/39cdf1d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/1600/1575/e7b18719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 7:00 AM to 8:00 PM, free cabanas](https://images.trvl-media.com/lodging/1000000/10000/1600/1575/b9dce53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/10000/1600/1575/9f136c56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Greenville Greenville 8.8/10 Excellent (523) "Hotel was very nice and clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcie CA $208 CA $235 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Greenville-Hotels-Hilton-Greenville.h1575.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/530000/522700/522664/da486ff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/530000/522700/522664/8d83f6a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/530000/522700/522664/234da06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/530000/522700/522664/0b9771d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Greenville Greenville 7.2/10 Good (390) "The hotel was clean and comfy. I would recommend and stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Austin CA $90 CA $102 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Greenville-Hotels-Econo-Lodge-Greenville.h522664.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21300/21285/589ff6ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21300/21285/3f856d3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/30000/21300/21285/fc9c3679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21285/7f1e0e96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Greenville, NC – ECU-Medical Center Greenville 6.6/10 (89) "I love to stay at this motel reasonable price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Natashi CA $102 CA $115 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Greenville-Hotels-Uptown-Greenville-Hotel.h21285.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07®ionId=908649044914896896&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Medical District Hotel Reviews ![Holiday Inn Express Greenville by IHG](//images.trvl-media.com/lodging/1000000/110000/102500/102482/30d4a3d9_y.jpg) ### Holiday Inn Express Greenville by IHG 10/10 Excellent "We felt very safe, comfortable, and the front desk staff were awesome! The fresh ground coffee was a nice surprise and delicious. I have stayed before, and will stay again. " [](https://expedia.ca/Greenville-Hotels-Holiday-Inn-Express-Greenville.h102482.Hotel-Information) ![Affordable Suites Greenville](//images.trvl-media.com/lodging/3000000/2690000/2682700/2682635/41b082ee_y.jpg) ### Affordable Suites Greenville 10/10 Excellent "Very affordable " [](https://expedia.ca/Greenville-Hotels-Affordable-Suites.h2682635.Hotel-Information) ![Country Inn & Suites by Radisson, Greenville, NC](//images.trvl-media.com/lodging/1000000/70000/62400/62311/d55c4c6b_y.jpg) ### Country Inn & Suites by Radisson, Greenville, NC 10/10 Excellent "I stay here just about every week, and it's consistently friendly and comfortable. " [](https://expedia.ca/Greenville-Hotels-Country-Inn-Suites-By-Radisson.h62311.Hotel-Information) ![Comfort Inn & Suites Greenville Near Convention Center](//images.trvl-media.com/lodging/1000000/220000/217400/217352/5ca75dae_y.jpg) ### Comfort Inn & Suites Greenville Near Convention Center 10/10 Excellent "Very helpful front desk staff. " [](https://expedia.ca/Greenville-Hotels-Wingate-By-Wyndham-Greenville.h217352.Hotel-Information) ![Baymont by Wyndham Greenville](//images.trvl-media.com/lodging/1000000/20000/10700/10685/b467b520_y.jpg) ### Baymont by Wyndham Greenville 10/10 Excellent "The hotel staff were very friendly, everyone was professional. I got a double queen room, the room was quaint, it was clean but there were signs of an insect problem. They did offer a variety of options for the continental breakfast menu and fresh hot coffee. Overall I enjoyed my stay. I would recommend this hotel for the price I can not complain. I will say make sure you check all your luggage before leaving so you don’t take any unwanted guests home with you." [](https://expedia.ca/Greenville-Hotels-Baymont-By-Wyndham-Greenville.h10685.Hotel-Information) ![Hampton Inn Washington](//images.trvl-media.com/lodging/1000000/900000/890500/890485/e3b75742_y.jpg) ### Hampton Inn Washington 10/10 Excellent "Breakfast was very good, staff friendly. Enjoyable stay." [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Washington.h890485.Hotel-Information) ![Hampton Inn Greenville](//images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/31fb46e7_y.jpg) ### Hampton Inn Greenville 10/10 Excellent "Great staff, good location, big, clean room. " [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Greenville.h2593867.Hotel-Information) ![Microtel Inn & Suites by Wyndham Greenville/University Medic](//images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/2e252281_y.jpg) ### Microtel Inn & Suites by Wyndham Greenville/University Medic 10/10 Excellent "I always book here! " [](https://expedia.ca/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-GreenvilleUniversity-Medic.h2009531.Hotel-Information) ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/10000/1600/1575/39cdf1d9_y.jpg) ### Hilton Greenville 10/10 Excellent "Hotel was very nice and clean. " [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h1575.Hotel-Information) ## Frequently asked questions ### What's Medical District like for family-friendly vacations? > The destination of Medical District is a good option if you've been considering a getaway with the kids. There are some entertaining activities you and the family might enjoy. Take to the air and fly into Greenville, NC (PGV-Pitt-Greenville), which is located 2.2 mi (3.5 km) from the center of Medical District. ### What's the best accommodation when traveling with kids to Medical District? > [Courtyard Marriott Greenville](https://www.expedia.ca/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information) is a hotel with a restaurant and free parking, and it's a top choice on Expedia for families. ### What's there to see and do with your family in Medical District? > While you are visiting Medical District, you and the family might want to check out some interesting spots such as Laupus Health Sciences Library, Arlington Crossing, and Williams Arena at Minges Coliseum. 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