Title: Book the Best Medical Center District SPA Resorts from CA $145 - Spa Hotels in Medical Center District, San Antonio | Expedia.ca [Medical Center District Travel Guide](https://expedia.ca/San-Antonio-Medical-Center-District.dx553248635978913844)[Vacation Rentals in San Antonio](https://expedia.ca/San-Antonio-Vacation-Rentals.d178303.Travel-Guide-VacationRentals)[Flights to San Antonio](https://expedia.ca/Cheap-Flights-To-San-Antonio.d178303.Travel-Guide-Flights)[Things to do in San Antonio](https://expedia.ca/Things-To-Do-In-San-Antonio.d178303.Travel-Guide-Activities)[Medical Center District Car Rentals](https://expedia.ca/Car-Rentals-In-Medical-Center-District.d553248635978913844.Car-Rental-Guide)[Medical Center District Vacations](https://expedia.ca/Medical-Center-District.d553248635978913844.Destination-Travel-Guides) ![River walk in San Antonio](https://images.trvl-media.com/place/553248635978913844/ef5a7faf-f6d9-4f7e-b325-ac477c5ad14d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Medical Center District, San Antonio from CA $145 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Medical Center District Spa Hotels Tonight [Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-12-15&endDate=2025-12-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 16 - Dec 17](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-12-16&endDate=2025-12-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-12-19&endDate=2025-12-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Medical Center District hotels with a spa ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/900000/897400/897388/2b6d39b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/897400/897388/e750b64e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/900000/897400/897388/d9ae0b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/897400/897388/fc81569e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Valencia Riverwalk [](https://www.expedia.ca/San-Antonio-Hotels-Hotel-Valencia-Riverwalk.h897388.Hotel-Information) Downtown San Antonio 9.4/10 Exceptional (2244) "Beautful hotel would definitely recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina Ashley CA $132 CA $195 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/San-Antonio-Hotels-Hotel-Valencia-Riverwalk.h897388.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/10700/10636/93e4ec15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/10700/10636/b322b66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/10700/10636/6744430c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6:00 AM to 10:00 PM, free cabanas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/10700/10636/580c2292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency San Antonio Riverwalk [](https://www.expedia.ca/San-Antonio-Hotels-Hyatt-Regency-San-Antonio-Riverwalk.h10636.Hotel-Information) Downtown San Antonio 9.2/10 Wonderful (1928) "Great stay overall " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa CA $210 CA $296 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/San-Antonio-Hotels-Hyatt-Regency-San-Antonio-Riverwalk.h10636.Hotel-Information) ![Couples treatment rooms, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/2000000/1240000/1234400/1234369/10aa60b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, alfresco dining ](https://images.trvl-media.com/lodging/2000000/1240000/1234400/1234369/cbd1f2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1240000/1234400/1234369/a6fac7f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1240000/1234400/1234369/079cef30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Contessa [](https://www.expedia.ca/San-Antonio-Hotels-Hotel-Contessa-Suites-On-The-Riverwalk.h1234369.Hotel-Information) Downtown San Antonio 9.0/10 Wonderful (3416) "Always a beautiful stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $182 CA $244 total includes taxes & fees Jan 15 - Jan 16, 2026 [](https://www.expedia.ca/San-Antonio-Hotels-Hotel-Contessa-Suites-On-The-Riverwalk.h1234369.Hotel-Information) ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/60000000/59770000/59768200/59768128/w3836h2557x4y3-835140a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/60000000/59770000/59768200/59768128/w3837h2557x3y3-981703a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/60000000/59770000/59768200/59768128/w3837h2557x3y3-a7037a4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/60000000/59770000/59768200/59768128/w3837h2534x3y3-290fc02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Thompson San Antonio - Riverwalk, by Hyatt [](https://www.expedia.ca/San-Antonio-Hotels-Thompson-San-Antonio.h59768128.Hotel-Information) Downtown San Antonio 9.0/10 Wonderful (916) "Room was amazing, staff was great, and the property was overall immaculate! Definitely staying here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rey CA $233 CA $322 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Antonio-Hotels-Thompson-San-Antonio.h59768128.Hotel-Information) ![Balcony view](https://images.trvl-media.com/lodging/1000000/20000/17400/17329/1aaa0955.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds | View from room](https://images.trvl-media.com/lodging/1000000/20000/17400/17329/a20972d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/17400/17329/a1a78274.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/17400/17329/aca78f83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni La Mansion del Rio [](https://www.expedia.ca/San-Antonio-Hotels-Omni-La-Mansion-Del-Rio.h17329.Hotel-Information) Downtown San Antonio 9.4/10 Exceptional (2823) "Beautiful hotel! Great location right on the riverwalk. I will definitely stay here again any time im in San Antonio." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $302 CA $362 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Antonio-Hotels-Omni-La-Mansion-Del-Rio.h17329.Hotel-Information) ![Body treatments, aromatherapy, body scrubs, facials](https://images.trvl-media.com/lodging/105000000/104350000/104343200/104343109/72f7603d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104350000/104343200/104343109/471a5828.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/105000000/104350000/104343200/104343109/2cd84d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/105000000/104350000/104343200/104343109/d243fede.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kimpton Santo San Antonio - Riverwalk by IHG [](https://www.expedia.ca/San-Antonio-Hotels-Kimpton-Santo.h104343109.Hotel-Information) Downtown San Antonio 9.4/10 Exceptional (639) "Great hotel, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darrin CA $222 CA $304 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/San-Antonio-Hotels-Kimpton-Santo.h104343109.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/27900/27848/w4000h2662x0y0-8fbd92da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool views, open daily](https://images.trvl-media.com/lodging/1000000/30000/27900/27848/ce01fda6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/27900/27848/7a721a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/27900/27848/4a007da3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza San Antonio Hotel & Spa, Autograph Collection [](https://www.expedia.ca/San-Antonio-Hotels-The-Otis-Hotel-San-Antonio.h27848.Hotel-Information) Downtown San Antonio 9.4/10 Exceptional (681) "Friendly staff place was clean!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla CA $208 CA $289 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/San-Antonio-Hotels-The-Otis-Hotel-San-Antonio.h27848.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035946/8edd0d72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch flat-screen TV with cable channels, TV, DVD player](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035946/8c66965a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035946/b77785bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035946/7608c65d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton San Antonio Brooks Hotel & Spa [](https://www.expedia.ca/San-Antonio-Hotels-Embassy-Suites-By-Hilton-San-Antonio-Brooks-Hotel-Spa.h17035946.Hotel-Information) Brooks City Base 9.2/10 Wonderful (1002) "Great hotel, clean, nice, and breakfast was top tier." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leonia CA $186 CA $220 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Antonio-Hotels-Embassy-Suites-By-Hilton-San-Antonio-Brooks-Hotel-Spa.h17035946.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/fa6b231c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/8a911d9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/08a9974f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/e3511f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort [](https://www.expedia.ca/San-Antonio-Hotels-Eilan-Hotel-And-Spa.h4919718.Hotel-Information) La Cantera District 8.4/10 Very good (1000) "Great place. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $169 CA $240 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Antonio-Hotels-Eilan-Hotel-And-Spa.h4919718.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/968100/968091/21f5f4df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/970000/968100/968091/1afa623d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free on-the-go breakfast on weekdays](https://images.trvl-media.com/lodging/1000000/970000/968100/968091/4f739480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/970000/968100/968091/0db911f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express San Antonio Rivercenter Area by IHG [](https://www.expedia.ca/San-Antonio-Hotels-Holiday-Inn-Express-San-Antonio-Rivercenter-Area.h968091.Hotel-Information) Near East Side 8.8/10 Excellent (1005) "Great time here and it was right next to everything myself and family needed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $124 CA $145 total includes taxes & fees Jan 15 - Jan 16, 2026 [](https://www.expedia.ca/San-Antonio-Hotels-Holiday-Inn-Express-San-Antonio-Rivercenter-Area.h968091.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-30&endDate=2025-12-31®ionId=553248635978913844&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Medical Center District ### Top Medical Center District attractions for a relaxing vacation In the heart of the Medical Center District, travellers can indulge in a plethora of wellness-focused activities that complement their luxury spa hotel stay. Begin your rejuvenation journey at the renowned Texas Medical Center, where you can explore the serene Hermann Park, featuring lush green spaces and tranquil waterways perfect for a leisurely stroll or a family picnic. Just a short drive away, the Houston Museum District offers a cultural escape, with the Houston Museum of Natural Science and the Contemporary Arts Museum, allowing you to unwind while engaging with fascinating exhibits. For those seeking a dose of retail therapy, The Galleria, one of the largest shopping centres in Texas, provides an array of upscale boutiques and fine dining options to satisfy even the most discerning shopper. After a day of exploration, retreat to one of the Medical Center District’s spa hotels, where you can immerse yourself in luxury treatments designed to relieve stress and rejuvenate your body. Picture yourself indulging in a signature massage or revitalising facial, followed by a dip in the pool or relaxation in a rooftop lounge with skyline views. With attentive service and thoughtfully designed wellness experiences, your stay promises to be both restorative and memorable. ## Top Medical Center District Hotel Reviews ![La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae_y.jpg) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW 10/10 Excellent "The hotel is clean and the staff are great " [](https://expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) ![Menger Hotel](https://images.trvl-media.com/lodging/1000000/10000/5900/5877/ae1a8ff6_y.jpg) ### Menger Hotel 10/10 Excellent "The staff was superb!!!!" [](https://expedia.ca/San-Antonio-Hotels-Menger-Hotel.h5877.Hotel-Information) ![La Quinta Inn & Suites by Wyndham San Antonio Riverwalk](https://images.trvl-media.com/lodging/1000000/30000/25700/25689/544ec14c_y.jpg) ### La Quinta Inn & Suites by Wyndham San Antonio Riverwalk 10/10 Excellent "Had an amazing time at the hotel " [](https://expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Riverwalk.h25689.Hotel-Information) ![Hyatt Vacation Club at Wild Oak Ranch, San Antonio](https://images.trvl-media.com/lodging/2000000/1120000/1113200/1113168/5058d5ba_y.jpg) ### Hyatt Vacation Club at Wild Oak Ranch, San Antonio 10/10 Excellent "It was nice and clean. " [](https://expedia.ca/San-Antonio-Hotels-Hyatt-Vacation-Club-At-Wild-Oak-Ranch.h1113168.Hotel-Information) ![Crockett Hotel](https://images.trvl-media.com/lodging/1000000/10000/1600/1534/a3dd07e6_y.jpg) ### Crockett Hotel 10/10 Excellent "Clean little hotel right in the middle of down town. Super close to giant mall and local attraction - Alamo" [](https://expedia.ca/San-Antonio-Hotels-Crockett-Hotel.h1534.Hotel-Information) ![Omni La Mansion del Rio](https://images.trvl-media.com/lodging/1000000/20000/17400/17329/1aaa0955_y.jpg) ### Omni La Mansion del Rio 10/10 Excellent "Excellent services !!! I recommend " [](https://expedia.ca/San-Antonio-Hotels-Omni-La-Mansion-Del-Rio.h17329.Hotel-Information) ![Hotel Contessa](https://images.trvl-media.com/lodging/2000000/1240000/1234400/1234369/a6fac7f7_y.jpg) ### Hotel Contessa 10/10 Excellent "street tacos were terrible I couldn't eat them, waiter asked if I wanted to take them I said no...." [](https://expedia.ca/San-Antonio-Hotels-Hotel-Contessa-Suites-On-The-Riverwalk.h1234369.Hotel-Information) ![Hyatt Regency San Antonio Riverwalk](https://images.trvl-media.com/lodging/1000000/20000/10700/10636/93e4ec15_y.jpg) ### Hyatt Regency San Antonio Riverwalk 10/10 Excellent "This location is very central for walks around the Riverwalk, The Alamo, La Villita and oodles of restaurants. Hotel was very clean, staff was helpful and very friendly" [](https://expedia.ca/San-Antonio-Hotels-Hyatt-Regency-San-Antonio-Riverwalk.h10636.Hotel-Information) ![Sonesta ES Suites San Antonio Downtown Alamo Plaza](https://images.trvl-media.com/lodging/1000000/50000/41200/41122/11513eda_y.jpg) ### Sonesta ES Suites San Antonio Downtown Alamo Plaza 10/10 Excellent "The Location was great. In the middle of many things. The staff was very friendly. The only down side is they are not car friendly. If you drive a car they want $50 per day for parking. This was sticker shock." [](https://expedia.ca/San-Antonio-Hotels-Sonesta-ES-Suites-San-Antonio-Downtown.h41122.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Medical Center District? ### What's there to see and do in Medical Center District? ### What is a Medical Center District spa hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Woodridge ](https://www.expedia.ca/3Star-Woodridge-San-Antonio-Hotels.s30-n553248635976386203-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Northwest Side ](https://www.expedia.ca/5Star-Northwest-Side-San-Antonio-Hotels.s50-n887264728595001344-0.Travel-Guide-Filter-Hotels) - [Business Hotels in Austin ](https://www.expedia.ca/Austin-Hotels-Business-Hotel.0-0-d178234-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Austin ](https://www.expedia.ca/Austin-Hotels-Casino-Hotel.0-0-d178234-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Austin ](https://www.expedia.ca/Austin-Hotels-Couples-Resorts-Hotels.0-0-d178234-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - 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[North Star Mall ](https://www.expedia.ca/North-Star-Mall-Uptown.d502628.Vacation-Attraction) - [Visit Balcones Heights ](https://www.expedia.ca/San-Antonio-Balcones-Heights.dx553248634999172368) - [Visit Castle Hills ](https://www.expedia.ca/San-Antonio-Castle-Hills.dx553248634999005679) - [Visit Leon Valley ](https://www.expedia.ca/San-Antonio-Leon-Valley.dx125419) - [Visit Oakland Estates ](https://www.expedia.ca/San-Antonio-Oakland-Estates.dx6230858) - [Usaa Corporate Office Headquarters ](https://www.expedia.ca/USAA-Corporate-Office-Headquarters-Medical-Center-District.d553248621593511346.Vacation-Attraction) - [Car rentals near USAA Corporate Office Headquarters ](https://www.expedia.ca/Car-Rentals-In-USAA-Corporate-Office-Headquarters.d553248621593511346.Car-Rental-Guide) - [Book Hotels in Medical Center District on Expedia.com ](https://www.expedia.com/Medical-Center-District-San-Antonio-Hotels-Spa-Hotel.0-n553248635978913844-0-tSpaHotel.Travel-Guide-Filter-Hotels)