Title: Book the Best SHOPPING Hotels in Medical Center District in 2025 | Expedia.ca [Medical Center District Travel Guide](https://expedia.ca/San-Antonio-Medical-Center-District.dx553248635978913844)[Vacation Rentals in San Antonio](https://expedia.ca/San-Antonio-Vacation-Rentals.d178303.Travel-Guide-VacationRentals)[Flights to San Antonio](https://expedia.ca/Cheap-Flights-To-San-Antonio.d178303.Travel-Guide-Flights)[Things to do in San Antonio](https://expedia.ca/Things-To-Do-In-San-Antonio.d178303.Travel-Guide-Activities)[Medical Center District Car Rentals](https://expedia.ca/Car-Rentals-In-Medical-Center-District.d553248635978913844.Car-Rental-Guide)[Medical Center District Vacations](https://expedia.ca/Medical-Center-District.d553248635978913844.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/8f3b15d1d7d73e712570109708f4e829.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Linda Cronan # Find Shopping Hotels in Medical Center District, TX ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Medical Center District Shopping Hotels Tonight [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-10-01&endDate=2025-10-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-10-02&endDate=2025-10-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635978913844&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Medical Center District Shopping Hotels ## Top Medical Center District Hotel Reviews ![Hyatt Vacation Club at Wild Oak Ranch, San Antonio](//images.trvl-media.com/lodging/2000000/1120000/1113200/1113168/5058d5ba_y.jpg) ### Hyatt Vacation Club at Wild Oak Ranch, San Antonio 10/10 Excellent "Wonderful lazy river " [](https://expedia.ca/San-Antonio-Hotels-Hyatt-Vacation-Club-At-Wild-Oak-Ranch.h1113168.Hotel-Information) ![Hyatt Regency San Antonio Riverwalk](//images.trvl-media.com/lodging/1000000/20000/10700/10636/93e4ec15_y.jpg) ### Hyatt Regency San Antonio Riverwalk 10/10 Excellent "Great " [](https://expedia.ca/San-Antonio-Hotels-Hyatt-Regency-San-Antonio-Riverwalk.h10636.Hotel-Information) ![The Westin San Antonio North](//images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6_y.jpg) ### The Westin San Antonio North 10/10 Excellent "It was a great property. The staff was very polite not all of them but them. The room was great. Everything was very clean. We liked that there was an indoor pool and an outdoor purple. They have frozen yogurt. It’s a very family friendly. They even have a gym and a sauna. The only thing we didn’t like was that they charge for parking." [](https://expedia.ca/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information) ![Hotel Valencia Riverwalk](//images.trvl-media.com/lodging/1000000/900000/897400/897388/2b6d39b3_y.jpg) ### Hotel Valencia Riverwalk 10/10 Excellent "The hotel was very stunning 😍 " [](https://expedia.ca/San-Antonio-Hotels-Hotel-Valencia-Riverwalk.h897388.Hotel-Information) ![Riverwalk Plaza](//images.trvl-media.com/lodging/1000000/290000/288400/288321/ef3ca433_y.jpg) ### Riverwalk Plaza 10/10 Excellent "Lots of shops nearby, was convenient to the event I was attending at the convention center. Good food at the gavel restaurant 😋 " [](https://expedia.ca/San-Antonio-Hotels-Riverwalk-Plaza.h288321.Hotel-Information) ![Omni La Mansion del Rio](//images.trvl-media.com/lodging/1000000/20000/17400/17329/1aaa0955_y.jpg) ### Omni La Mansion del Rio 10/10 Excellent "Right on River walk " [](https://expedia.ca/San-Antonio-Hotels-Omni-La-Mansion-Del-Rio.h17329.Hotel-Information) ![Drury Plaza Hotel San Antonio Riverwalk](//images.trvl-media.com/lodging/2000000/1540000/1534300/1534252/232ec435_y.jpg) ### Drury Plaza Hotel San Antonio Riverwalk 10/10 Excellent "An excellent place to stay, outstanding location and breakfast menu! Very clean and quiet!" [](https://expedia.ca/San-Antonio-Hotels-Drury-Plaza-Hotel-San-Antonio-Riverwalk.h1534252.Hotel-Information) ![Menger Hotel](//images.trvl-media.com/lodging/1000000/10000/5900/5877/ae1a8ff6_y.jpg) ### Menger Hotel 10/10 Excellent "Really interesting historical property. Antiques and historical artifacts everywhere. Would stay again." [](https://expedia.ca/San-Antonio-Hotels-Menger-Hotel.h5877.Hotel-Information) ![Sonesta ES Suites San Antonio Downtown Alamo Plaza](//images.trvl-media.com/lodging/1000000/50000/41200/41122/11513eda_y.jpg) ### Sonesta ES Suites San Antonio Downtown Alamo Plaza 10/10 Excellent "The room was spacious and clean. Loce the kitchenette and fridge in the room. Rivercity mall is about a 7 min walk which you can go through to access the riverwalk. The hotel Valet parking is convenient and easy, free breakfast included with stay " [](https://expedia.ca/San-Antonio-Hotels-Sonesta-ES-Suites-San-Antonio-Downtown.h41122.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [3 Star Hotels in Woodridge](https://www.expedia.ca/3Star-Woodridge-San-Antonio-Hotels.s30-n553248635976386203-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Northwest Side](https://www.expedia.ca/5Star-Northwest-Side-San-Antonio-Hotels.s50-n887264728595001344-0.Travel-Guide-Filter-Hotels) - [Business Hotels in Austin](https://www.expedia.ca/Austin-Hotels-Business-Hotel.0-0-d178234-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Austin](https://www.expedia.ca/Austin-Hotels-Casino-Hotel.0-0-d178234-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Austin](https://www.expedia.ca/Austin-Hotels-Couples-Resorts-Hotels.0-0-d178234-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - 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[North Star Mall](https://www.expedia.ca/North-Star-Mall-Uptown.d502628.Vacation-Attraction) - [Visit Balcones Heights](https://www.expedia.ca/San-Antonio-Balcones-Heights.dx553248634999172368) - [Visit Castle Hills](https://www.expedia.ca/San-Antonio-Castle-Hills.dx553248634999005679) - [Visit Leon Valley](https://www.expedia.ca/San-Antonio-Leon-Valley.dx125419) - [Visit Oakland Estates](https://www.expedia.ca/San-Antonio-Oakland-Estates.dx6230858) - [Usaa Corporate Office Headquarters](https://www.expedia.ca/USAA-Corporate-Office-Headquarters-Medical-Center-District.d553248621593511346.Vacation-Attraction) - [Car rentals near USAA Corporate Office Headquarters](https://www.expedia.ca/Car-Rentals-In-USAA-Corporate-Office-Headquarters.d553248621593511346.Car-Rental-Guide)