Title: Book the Best Mebane LUXURY Hotels - Upscale Hotels in Mebane, NC | Expedia.ca [Hotels in Mebane](https://expedia.ca/Mebane-Hotels.d180961.Travel-Guide-Hotels)[Vacation Rentals in Mebane](https://expedia.ca/Mebane-Vacation-Rentals.d180961.Travel-Guide-VacationRentals)[Flights to Mebane](https://expedia.ca/Cheap-Flights-To-Mebane.d180961.Travel-Guide-Flights)[Mebane Car Rentals](https://expedia.ca/Car-Rentals-In-Mebane.d180961.Car-Rental-Guide)[Mebane Vacation Packages](https://expedia.ca/Mebane.d180961.Destination-Travel-Guides) ![Farm surrounded by a harvested field](https://images.trvl-media.com/place/180961/5f702896-f7fc-45a7-9280-3872f62bf7f7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/180961/5f702896-f7fc-45a7-9280-3872f62bf7f7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mebane Luxury Hotels Tonight [Feb 3 - Feb 4](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2026-02-03&endDate=2026-02-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2026-02-04&endDate=2026-02-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Mebane Hotel Reviews ![Millennium Durham](https://images.trvl-media.com/lodging/1000000/30000/26400/26351/309f8e95_y.jpg) ### Millennium Durham 10/10 Excellent "Wonderful friendly staff very clean . Highly recommended." [](https://expedia.ca/Raleigh-Hotels-Millennium-Durham.h26351.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill](https://images.trvl-media.com/lodging/1000000/170000/165800/165760/a2feecd0_y.jpg) ### La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill 10/10 Excellent "Rooms were updated very nice" [](https://expedia.ca/Raleigh-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Univ-Area-Chapel-Hill.h165760.Hotel-Information) ![University Inn Durham next to Duke University Medical Center](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/aaa7829c_y.jpg) ### University Inn Durham next to Duke University Medical Center 10/10 Excellent "Cleanliness." [](https://expedia.ca/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information) ![JB Duke Hotel](https://images.trvl-media.com/lodging/16000000/15940000/15936000/15935986/22366c65_y.jpg) ### JB Duke Hotel 10/10 Excellent "Yes" [](https://expedia.ca/Raleigh-Hotels-JB-Duke-Hotel.h15935986.Hotel-Information) ![DoubleTree Suites by Hilton Raleigh - Durham](https://images.trvl-media.com/lodging/1000000/20000/13200/13139/7fb5aa3f_y.jpg) ### DoubleTree Suites by Hilton Raleigh - Durham 10/10 Excellent "The room was great & the staff was so nice !! You get cookies when you check in & they was bomb !" [](https://expedia.ca/Raleigh-Hotels-DoubleTree-Suites-By-Hilton-Raleigh-Durham.h13139.Hotel-Information) ![Washington Duke Inn & Golf Club](https://images.trvl-media.com/lodging/1000000/20000/10900/10844/fb0066de_y.jpg) ### Washington Duke Inn & Golf Club 10/10 Excellent "The room was beautiful! The room amenities were fantastic! I especially loved the kind and courteous staff. The food was amazing. We had a wonderful dinner at the Fairview restaurant and ate a hearty room service breakfast in our room. " [](https://expedia.ca/Raleigh-Hotels-Washington-Duke-Inn-Golf-Club.h10844.Hotel-Information) ![The Carolina Inn, a Destination by Hyatt Hotel](https://images.trvl-media.com/lodging/1000000/20000/16200/16166/07b8dabe_y.jpg) ### The Carolina Inn, a Destination by Hyatt Hotel 10/10 Excellent "Awesomr" [](https://expedia.ca/Raleigh-Hotels-The-Carolina-Inn.h16166.Hotel-Information) ## Frequently asked questions ### Which area of Mebane is best to stay in for luxury hotels? > This area, located just off Interstate 40, is primarily a shopping and dining district but also hosts several newer, high-quality hotels. It's designed for convenience, with easy access to the motorway for those travelling by car. You'll find a range of restaurants within a short walk or drive, from casual eateries to more upscale dining experiences. > > > Couples looking for a comfortable and convenient stay often find this area ideal. The hotels here typically offer amenities such as spacious rooms, modern decor, and sometimes even high-end fitness equipment or indoor pools, ensuring a relaxing trip. The proximity to the outlets also provides opportunities for a bit of retail therapy. ### How much does a luxury hotel in Mebane cost? ### What luxury activities and experiences are there in Mebane? > This central area offers a pleasant blend of historic charm and modern conveniences. You'll find a selection of upscale eateries, unique boutiques, and local art galleries within a short stroll of each other. The layout is very walkable, making it easy to explore the town's offerings. The downtown area is particularly appealing to couples looking for a relaxed yet refined getaway. > > > Couples will find the downtown area ideal for its culinary scene and boutique shopping. You can enjoy gourmet dining experiences at establishments offering farm-to-table cuisine, often with extensive wine lists. Afterwards, you might browse independent shops for bespoke gifts or local art, providing a more intimate and personalised shopping experience. The local craft breweries and distilleries also offer tasting experiences that can be a nice way to spend an afternoon. > > > For those seeking a tranquil retreat with high-end amenities, staying slightly outside the immediate downtown area, but still within a short drive, offers advantages. Many luxury hotels here provide more space and privacy, often featuring amenities like private patios, high-end fitness equipment, and personalised concierge services. ### How can I save on a luxury hotel in Mebane with Expedia? ### Is it cheaper to book a luxury Mebane hotel and flights as a package? ### Can I cancel my luxury hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Farmstay in Burlington ](https://www.expedia.ca/Burlington-Agritourism.d6234-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Burlington ](https://www.expedia.ca/Burlington-Apart-Hotels.d6234-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Burlington ](https://www.expedia.ca/Burlington-Bed-And-Breakfast.d6234-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Burlington ](https://www.expedia.ca/Burlington-Guest-Houses.d6234-aaGuestHouses.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Burlington ](https://www.expedia.ca/Burlington-Hotels-Beach-Hotel.0-0-d6234-tBeachHotel.Travel-Guide-Filter-Hotels) - 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