Title: Mayo Clinic Scottsdale in Central Scottsdale - Tours and Activities | Expedia.ca [Mayo Clinic Scottsdale Hotels](https://expedia.ca/Mayo-Clinic-Scottsdale-Hotels.0-l6131819-0.Travel-Guide-Filter-Hotels)[Mayo Clinic Scottsdale Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-Clinic-Scottsdale.d6131819.Car-Rental-Guide)[Central Scottsdale Vacations](https://expedia.ca/Central-Scottsdale.d553248635976007832.Destination-Travel-Guides) # Mayo Clinic Scottsdale Tours and Activities ## Visit Mayo Clinic Scottsdale Activities --- --- ## Plan a trip to see Mayo Clinic Scottsdale Price found within the past 48 hours. Click for updated prices. ![Raintree at Phoenix South Mountain Preserve](https://images.trvl-media.com/lodging/5000000/4680000/4673100/4673059/e257ae53_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Raintree at Phoenix South Mountain Preserve South Mountain CA $933 per person Mar 28 - Apr 2 found 1 day ago Roundtrip flight included Vancouver (YVR) to Phoenix (PHX) 8.4/10 Very Good! (130 reviews) Great staff Room clean Need to update TVsand appliances Reviewed on Dec 15, 2025 ![Sedona Springs Resort](https://images.trvl-media.com/lodging/1000000/890000/887300/887243/ea20609b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Sedona Springs Resort West Sedona CA $1,299 per person Mar 25 - Mar 30 found 10 hours ago Roundtrip non-stop flight included Edmonton (YEG) to Phoenix (PHX) 9.2/10 Wonderful! (1,180 reviews) Clean quiet spacious Reviewed on Jan 19, 2026 ![Royal Palms Resort and Spa, part of Hyatt](https://images.trvl-media.com/lodging/1000000/800000/791200/791197/a9b4312a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Royal Palms Resort and Spa, part of Hyatt Camelback East CA $2,207 per person Mar 29 - Apr 3 found 1 day ago Roundtrip non-stop flight included Edmonton (YEG) to Phoenix (PHX) 9.2/10 Wonderful! (1,001 reviews) My husband and I both agreed that this was the most beautiful boutique hotel we’ve stayed at in Phoenix. Very quaint, gorgeous property and mountain views along with a wonderful Spa. Reviewed on Jan 15, 2026 ### Popular places to visit ![Fountain Hills Botanical Garden](https://images.trvl-media.com/place/553248621532642948/3b3d7e74-33e0-4f7f-801f-dec8c0422802.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Fountain Hills Botanical Garden Explore the lovely green spaces of Fountain Hills Botanical Garden and enjoy the golf courses in Fountain Hills. Attend a sporting event or simply enjoy the lively bars while you're in the area. [](https://expedia.ca/Fountain-Hills-Botanical-Garden-Phoenix.d553248621532642948.Vacation-Attraction) ![Fountain Hills Fountain](https://images.trvl-media.com/place/6295102/4674e49b-00f8-452a-8551-fa91907fbae1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Fountain Hills Fountain Fountain Hills Fountain is just one of the places to see in Fountain Hills, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [](https://expedia.ca/Fountain-Hills-Fountain-Phoenix.d6295102.Vacation-Attraction) ![Butterfly Wonderland showing animals and wildflowers](https://images.trvl-media.com/place/553248621561887373/542afdda-0760-4732-bbc9-a4438d17fad8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Butterfly Wonderland Enjoy an outing to Butterfly Wonderland during your stay in Scottsdale. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [](https://expedia.ca/Butterfly-Wonderland-Phoenix.d553248621561887373.Vacation-Attraction) ![OdySea Aquarium](https://images.trvl-media.com/place/553248635056398497/6e1e4260-8226-4f51-990c-9fcf54418d87.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### OdySea Aquarium Make time in your itinerary to visit the sea life who live at OdySea Aquarium during your visit to Scottsdale. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [](https://expedia.ca/OdySea-Aquarium-Phoenix.d553248635056398497.Vacation-Attraction) ![Phoenix_TalkingStickResortCasino_553248621555612463_02](https://images.trvl-media.com/place/553248621555612463/011eaf9d-740d-4967-b44d-3f754616f8ab.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Talking Stick Resort Casino Why not try your luck with a visit to Talking Stick Resort Casino where you can enjoy the entertainment at this popular casino in Scottsdale? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [](https://expedia.ca/Talking-Stick-Resort-Casino-Phoenix.d553248621555612463.Vacation-Attraction) #### Eagle Mountain Golf Course Play a round of golf at Eagle Mountain Golf Course and enjoy other activities in Fountain Hills such as running. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [](https://expedia.ca/Eagle-Mountain-Golf-Course-Eagle-Mountain.d6158120.Vacation-Attraction) --- ## Best Lodging Options Near Mayo Clinic Scottsdale ## Check availability on hotels close to Mayo Clinic Scottsdale [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6131819&startDate=2026-01-21&endDate=2026-01-22)[Jan 21 - Jan 22](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6131819&startDate=2026-01-21&endDate=2026-01-22) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6131819&startDate=2026-01-22&endDate=2026-01-23)[Jan 22 - Jan 23](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6131819&startDate=2026-01-22&endDate=2026-01-23) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6131819&startDate=23%2F01%2F2026&endDate=25%2F01%2F2026)[Jan 23 - Jan 25](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6131819&startDate=23%2F01%2F2026&endDate=25%2F01%2F2026) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6131819&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026)[Jan 30 - Feb 1](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6131819&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026) ![Sonesta Select Scottsdale at Mayo Clinic Campus](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/3d96914a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sonesta Select Scottsdale at Mayo Clinic Campus 13444 E Shea Blvd Scottsdale AZ [](https://expedia.ca/Phoenix-Hotels-Sonesta-Select-Scottsdale-At-Mayo-Clinic-Campus.h9767.Hotel-Information) ![Poolside Fun | Pet Friendly Stay in Prime Scottsdale Location!](https://images.trvl-media.com/lodging/113000000/112450000/112441600/112441584/c0099ab4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Poolside Fun | Pet Friendly Stay in Prime Scottsdale Location! Scottsdale AZ [](https://expedia.ca/Phoenix-Hotels-White-Horse-Pool.h112441584.Hotel-Information) ![Private Pickleball Court Mountain Views Oasis](https://images.trvl-media.com/lodging/108000000/107400000/107398300/107398268/57190c04_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Pickleball Court Mountain Views Oasis Scottsdale Arizona [](https://expedia.ca/Phoenix-Hotels-Private-Pickleball-Court-Mountain-Views-Oasis.h107398268.Hotel-Information) ![Spectacular North Scottsdale desert home](https://images.trvl-media.com/lodging/34000000/33570000/33569100/33569063/992971fe_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Spectacular North Scottsdale desert home Scottsdale AZ [](https://expedia.ca/Phoenix-Hotels-Espectacular-North-Scottsdale-Desierto-Inicio.h33569063.Hotel-Information) ![Scottsdale Paradise- POOL, Spa, Pickleball/Basketball, Fire Pit & Great HIKING!](https://images.trvl-media.com/lodging/96000000/95380000/95375400/95375325/w2000h1332x0y1-282f1550_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Scottsdale Paradise- POOL, Spa, Pickleball/Basketball, Fire Pit & Great HIKING! Scottsdale AZ [](https://expedia.ca/Phoenix-Hotels-Scottsdale-Paradise-POOL.h95375325.Hotel-Information) ![Inn at Eagle Mountain](https://images.trvl-media.com/lodging/1000000/110000/103500/103478/acc31d08_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Inn at Eagle Mountain 9800 N Summer Hill Blvd Fountain Hills AZ [](https://expedia.ca/Phoenix-Hotels-Inn-At-Eagle-Mountain.h103478.Hotel-Information) ![Desert Retreat | Private Sport Court & Pet Friendly](https://images.trvl-media.com/lodging/36000000/35710000/35700900/35700830/8036c93e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Desert Retreat | Private Sport Court & Pet Friendly Scottsdale AZ [](https://expedia.ca/Phoenix-Hotels-New-Listing-5-Bedroom-Home-With-Beautiful-Pool-And-Outdoor-Space.h35700830.Hotel-Information) ![ADERO Scottsdale Resort, Autograph Collection](https://images.trvl-media.com/lodging/1000000/580000/577900/577892/01b1fdc1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### ADERO Scottsdale Resort, Autograph Collection 13225 North Eagle Ridge Drive Scottsdale AZ [](https://expedia.ca/Phoenix-Hotels-ADERO-Scottsdale.h577892.Hotel-Information) ![Luxury Casita at Desert Estate in Scottsdale](https://images.trvl-media.com/lodging/71000000/70090000/70084900/70084840/b7950e38_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Luxury Casita at Desert Estate in Scottsdale Scottsdale AZ [](https://expedia.ca/Phoenix-Hotels-Luxury-Casita-At-Desert-Estate.h70084840.Hotel-Information) [See all 8,291 properties in Mayo Clinic Scottsdale](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6131819) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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[Hole in the Rock ](https://www.expedia.ca/Hole-In-The-Rock-Camelback-East.d6200179.Vacation-Attraction) - [Kierland Commons ](https://www.expedia.ca/Kierland-Commons-Paradise-Valley-Village.d6160567.Vacation-Attraction) - [Longbow Golf Club ](https://www.expedia.ca/Longbow-Golf-Club-East-Mesa.d6294765.Vacation-Attraction) - [Mccormick Ranch Golf Club ](https://www.expedia.ca/McCormick-Ranch-Golf-Club-Phoenix.d553248621555612455.Vacation-Attraction) - [Mccormick-Stillman Railroad Park ](https://www.expedia.ca/McCormick-Stillman-Railroad-Park-Phoenix.d553248621555612454.Vacation-Attraction) - [Mesa Vacations ](https://www.expedia.ca/Mesa.d8820.Destination-Travel-Guides) - [Musical Instrument Museum ](https://www.expedia.ca/Musical-Instrument-Museum-Desert-Ridge.d6140906.Vacation-Attraction) - [North Scottsdale Vacations ](https://www.expedia.ca/North-Scottsdale.d553248635074842178.Destination-Travel-Guides) - [Odysea Aquarium ](https://www.expedia.ca/OdySea-Aquarium-Phoenix.d553248635056398497.Vacation-Attraction) - [Old Town Vacations ](https://www.expedia.ca/Old-Town.d6160565.Destination-Travel-Guides) - [Orange Tree Golf Course ](https://www.expedia.ca/Orange-Tree-Golf-Course-Paradise-Valley-Village.d553248621555612473.Vacation-Attraction) - [Paradise Valley Vacations ](https://www.expedia.ca/Paradise-Valley.d55175.Destination-Travel-Guides) - [Visit Mirage Mountain ](https://www.expedia.ca/Phoenix-Mirage-Mountain.dx553248635976473432) - [Visit Mountainside Plaza ](https://www.expedia.ca/Phoenix-Mountainside-Plaza.dx553248635976480453) - [Visit Sienna Canyon ](https://www.expedia.ca/Phoenix-Sienna-Canyon.dx553248635976477067) - [Rawhide Western Town & Steakhouse ](https://www.expedia.ca/Rawhide-Western-Town-Steakhouse-Paradise-Valley-Village.d553248621533114162.Vacation-Attraction) - [Salt River Tubing ](https://www.expedia.ca/Salt-River-Tubing-East-Mesa.d553248621532642905.Vacation-Attraction) - [Scottsdale Museum of Contemporary Art ](https://www.expedia.ca/Scottsdale-Museum-Of-Contemporary-Art-Old-Town.d6085781.Vacation-Attraction) - [Scottsdale Quarter ](https://www.expedia.ca/Scottsdale-Quarter-Thunderbird-Industrial-Airpark.d6172141.Vacation-Attraction) - [Scottsdale Vacations ](https://www.expedia.ca/Scottsdale.d9829.Destination-Travel-Guides) - [Starfire Golf Club at Scottsdale Country Club ](https://www.expedia.ca/Starfire-Golf-Club-At-Scottsdale-Country-Club-Central-Scottsdale.d553248621555612474.Vacation-Attraction) - [Stratford Vacations ](https://www.expedia.ca/Stratford.d553248635975749707.Destination-Travel-Guides) - [Troon North Golf Club ](https://www.expedia.ca/Troon-North-Golf-Club-Pinnacle-Peak.d6085785.Vacation-Attraction) - [Usery Mountain Regional Park ](https://www.expedia.ca/Usery-Mountain-Regional-Park-Phoenix.d6294769.Vacation-Attraction) - [We-Ko-Pa Golf Club ](https://www.expedia.ca/We-Ko-Pa-Golf-Club-Phoenix.d6085721.Vacation-Attraction) - [Western Spirit: Scottsdale's Museum of the West ](https://www.expedia.ca/Western-Spirit-Scottsdales-Museum-Of-The-West-Old-Town.d553248621593240822.Vacation-Attraction) - [Car rental Fountain Hills ](https://www.expedia.ca/Car-Rentals-In-Fountain-Hills.d7820.Car-Rental-Guide) - [Things to do in Fountain Hills ](https://www.expedia.ca/Things-To-Do-In-Fountain-Hills.d7820.Travel-Guide-Activities)