Title: Hotels by Sonesta Hotel in Mayo Clinic from CA $109 | Expedia.ca [Mayo Clinic Travel Guide](https://expedia.ca/Phoenix-Mayo-Clinic.dx553248635976008216)[Vacation Rentals in Phoenix](https://expedia.ca/Phoenix-Vacation-Rentals.d178298.Travel-Guide-VacationRentals)[Flights to Phoenix](https://expedia.ca/Cheap-Flights-To-Phoenix.d178298.Travel-Guide-Flights)[Things to do in Phoenix](https://expedia.ca/Things-To-Do-In-Phoenix.d178298.Travel-Guide-Activities)[Mayo Clinic Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-Clinic.d553248635976008216.Car-Rental-Guide)[Mayo Clinic Vacations](https://expedia.ca/Mayo-Clinic.d553248635976008216.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Sonesta Hotel in Mayo Clinic from CA $109 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-09-30&endDate=2025-10-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-10-01&endDate=2025-10-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mayo Clinic Sonesta Hotel Hotels ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/310000/306700/306691/41b8cfd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/310000/306700/306691/7575bf77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, Tempur-Pedic beds](https://images.trvl-media.com/lodging/1000000/310000/306700/306691/d981acd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/310000/306700/306691/77ad803a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta ES Suites Tempe South Tempe 7.4/10 Good (1020) "Beautiful room with great amenities in a wonderful location. " CA $95 CA $109 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Phoenix-Hotels-Sonesta-ES-Suites-Tempe.h306691.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/41900/41812/81f46681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/41900/41812/a96eaaed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41900/41812/229b01cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41900/41812/c771f1d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta Select Tempe Downtown Downtown Tempe 8.4/10 Very good (1026) "Had a pleasant stay. " CA $137 CA $157 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Phoenix-Hotels-Sonesta-Select-Tempe.h41812.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-15&endDate=2025-10-16®ionId=553248635976008216&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Clinic-Phoenix-Hotels-Sonesta-Hotel.0-n553248635976008216-0--bSonestaHotel.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Clinic-Phoenix-Hotels-Sonesta-Hotel.0-n553248635976008216-0--bSonestaHotel.Travel-Guide-Filter-Hotels) ## Top Mayo Clinic Hotel Reviews ![Hampton Inn & Suites Phoenix Downtown](//images.trvl-media.com/lodging/23000000/22280000/22270800/22270752/755830f0_y.jpg) ### Hampton Inn & Suites Phoenix Downtown 10/10 Excellent "Great location. Wonderful staff!" [](https://expedia.ca/Phoenix-Hotels-Hampton-Inn-Suites-Phoenix-Downtown.h22270752.Hotel-Information) ![ Scottsdale Parkview Resort](//images.trvl-media.com/lodging/1000000/10000/9600/9531/b9276b91_y.jpg) ### Scottsdale Parkview Resort 10/10 Excellent "Highly recommend!" [](https://expedia.ca/Phoenix-Hotels-Scottsdale-Parkview-Resort.h9531.Hotel-Information) ![Aloft Phoenix Airport](//images.trvl-media.com/lodging/3000000/2960000/2957300/2957204/c4f39b6f_y.jpg) ### Aloft Phoenix Airport 10/10 Excellent "Early check in. Shuttle service was great." [](https://expedia.ca/Phoenix-Hotels-Aloft-Phoenix-Airport.h2957204.Hotel-Information) ![Omni Scottsdale Resort & Spa at Montelucia](//images.trvl-media.com/lodging/1000000/10000/2300/2263/38914575_y.jpg) ### Omni Scottsdale Resort & Spa at Montelucia 10/10 Excellent "Big rooms, clean resort, everything on site, nice pools, friendly staff. " [](https://expedia.ca/Phoenix-Hotels-Omni-Scottsdale-Resort-Spa-At-Montelucia.h2263.Hotel-Information) ![Embassy Suites by Hilton Scottsdale Resort](//images.trvl-media.com/lodging/1000000/10000/100/98/245e6984_y.jpg) ### Embassy Suites by Hilton Scottsdale Resort 10/10 Excellent "The staff is terrific - friendly yet professional. The property is clean, safe, beds are super comfy. Air conditioner is noisy though. Breakfast is delicious, but skip the salads at the Azul restaurant. Would definitely stay again. " [](https://expedia.ca/Phoenix-Hotels-Embassy-Suites-By-Hilton-Scottsdale-Resort.h98.Hotel-Information) ![Hotel Valley Ho](//images.trvl-media.com/lodging/1000000/20000/15300/15298/dfaa8e35_y.jpg) ### Hotel Valley Ho 10/10 Excellent "The room was clean and comfortable, the staff were all professional and friendly. We particularly enjoyed the live music in the dining area in the evening." [](https://expedia.ca/Phoenix-Hotels-Hotel-Valley-Ho.h15298.Hotel-Information) ![FOUNDRE Phoenix](//images.trvl-media.com/lodging/1000000/10000/7300/7250/10fc2bd0_y.jpg) ### FOUNDRE Phoenix 10/10 Excellent "Very clean and the beds were comfortable" [](https://expedia.ca/Phoenix-Hotels-FOUNDRE-Phoenix.h7250.Hotel-Information) ![Hilton Phoenix Airport](//images.trvl-media.com/lodging/1000000/30000/26000/25957/3450908d_y.jpg) ### Hilton Phoenix Airport 10/10 Excellent "Loved it" [](https://expedia.ca/Phoenix-Hotels-Hilton-Phoenix-Airport.h25957.Hotel-Information) ![Arizona Grand Resort & Spa](//images.trvl-media.com/lodging/1000000/10000/2800/2774/225d2d95_y.jpg) ### Arizona Grand Resort & Spa 10/10 Excellent "It really gives you a luxurious feel! The dining is epic! Waterpark is epic! Although, some of the hot tubs didn’t work, which was weird" [](https://expedia.ca/Phoenix-Hotels-Arizona-Grand-Resort-Spa.h2774.Hotel-Information) ## Find out more about Mayo Clinic ## Mayo Clinic Hotels Guide Expedia.ca offers a selection of 12934 hotels in Mayo Clinic. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Mayo Clinic. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Mayo Clinic neighborhood you prefer. Go ahead. 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[Pet-Friendly Hotels in Scottsdale Ranch](https://www.expedia.ca/Scottsdale-Ranch-Phoenix-Hotels-Pet-Friendly-Hotel.0-n553248635976480109-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Scottsdale Ranch Hotels](https://www.expedia.ca/Scottsdale-Ranch-Phoenix-Hotels.0-n553248635976480109-0.Travel-Guide-Filter-Hotels) - [Highgate Independent Hotels in Sonoran Heights](https://www.expedia.ca/Sonoran-Heights-Phoenix-Hotels-Highgate-Independent.0-n553248635976468498-0--bHighgateIndependent.Travel-Guide-Filter-Hotels) - [Sonoran Heights Hotels](https://www.expedia.ca/Sonoran-Heights-Phoenix-Hotels.0-n553248635976468498-0.Travel-Guide-Filter-Hotels) - [Stonehaven Hotels](https://www.expedia.ca/Stonehaven-Phoenix-Hotels.0-n553248635976479675-0.Travel-Guide-Filter-Hotels) - [Fairmont Hotels in Su Casa](https://www.expedia.ca/Su-Casa-Phoenix-Hotels-Fairmont.0-n553248635976473319-0--bFairmont.Travel-Guide-Filter-Hotels) - [Hotels near SunRidge Canyon Golf Club](https://www.expedia.ca/SunRidge-Canyon-Golf-Club-Hotels.0-l6158124-0.Travel-Guide-Filter-Hotels) - [Fairmont Hotels in The Joshua Tree](https://www.expedia.ca/The-Joshua-Tree-Phoenix-Hotels-Fairmont.0-n553248635976475072-0--bFairmont.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in The Joshua Tree](https://www.expedia.ca/The-Joshua-Tree-Phoenix-Hotels-Marriott-Hotels-Resorts.0-n553248635976475072-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in The Joshua Tree](https://www.expedia.ca/The-Joshua-Tree-Phoenix-Hotels-Motel-6.0-n553248635976475072-0--bMotel6.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Town Center](https://www.expedia.ca/Town-Center-Phoenix-Hotels-Beach-Hotel.0-n553248635976481029-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Town Center](https://www.expedia.ca/Town-Center-Phoenix-Hotels-Romantic-Hotel.0-n553248635976481029-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Fairmont Hotels in Villa De Vallarta](https://www.expedia.ca/Villa-De-Vallarta-Phoenix-Hotels-Fairmont.0-n553248635976386484-0--bFairmont.Travel-Guide-Filter-Hotels) - [Fairmont Hotels in Villa La Playa](https://www.expedia.ca/Villa-La-Playa-Phoenix-Hotels-Fairmont.0-n553248635976383881-0--bFairmont.Travel-Guide-Filter-Hotels) - [Flights to Fountain Hills](https://www.expedia.ca/Cheap-Flights-To-Fountain-Hills.d7820.Travel-Guide-Flights) - [Flights to Phoenix](https://www.expedia.ca/Cheap-Flights-To-Phoenix.d178298.Travel-Guide-Flights) - [Flights from Toronto (YYZ) to Phoenix (PHX)](https://www.expedia.ca/lp/flights/yyz/phx/toronto-to-phoenix) - [Mayo Clinic Scottsdale](https://www.expedia.ca/Mayo-Clinic-Scottsdale-Central-Scottsdale.d6131819.Vacation-Attraction) - [Visit Mirage Mountain](https://www.expedia.ca/Phoenix-Mirage-Mountain.dx553248635976473432) - [Visit Mountainside Plaza](https://www.expedia.ca/Phoenix-Mountainside-Plaza.dx553248635976480453) - [Visit Sienna Canyon](https://www.expedia.ca/Phoenix-Sienna-Canyon.dx553248635976477067) - [Car rental Fountain Hills](https://www.expedia.ca/Car-Rentals-In-Fountain-Hills.d7820.Car-Rental-Guide) - [Hertz Rental Cars in Fountain Hills](https://www.expedia.ca/Hertz-Car-Rentals-In-Fountain-Hills.d7820-c40.Car-Rental-Guide-Suppliers) - [Fountain Hills Vacation Rentals](https://www.expedia.ca/Fountain-Hills-Vacation-Rentals.d7820.Travel-Guide-VacationRentals) - [Things to do in Fountain Hills](https://www.expedia.ca/Things-To-Do-In-Fountain-Hills.d7820.Travel-Guide-Activities) - [Book Hotels in Mayo Clinic on Expedia.com](https://www.expedia.com/Mayo-Clinic-Phoenix-Hotels-Sonesta-Hotel.0-n553248635976008216-0--bSonestaHotel.Travel-Guide-Filter-Hotels)