Title: Hotels by Highgate Independent in Mayo Clinic from CA $210 | Expedia.ca [Mayo Clinic Travel Guide](https://expedia.ca/Phoenix-Mayo-Clinic.dx553248635976008216)[Vacation Rentals in Phoenix](https://expedia.ca/Phoenix-Vacation-Rentals.d178298.Travel-Guide-VacationRentals)[Flights to Phoenix](https://expedia.ca/Cheap-Flights-To-Phoenix.d178298.Travel-Guide-Flights)[Things to do in Phoenix](https://expedia.ca/Things-To-Do-In-Phoenix.d178298.Travel-Guide-Activities)[Mayo Clinic Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-Clinic.d553248635976008216.Car-Rental-Guide)[Mayo Clinic Vacations](https://expedia.ca/Mayo-Clinic.d553248635976008216.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Highgate Independent in Mayo Clinic from CA $210 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mayo Clinic Highgate Independent ![Bar (on property)](https://images.trvl-media.com/lodging/82000000/81220000/81214700/81214699/190b0221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/82000000/81220000/81214700/81214699/e8258d31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/82000000/81220000/81214700/81214699/d36c6de2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/82000000/81220000/81214700/81214699/cd0c512c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Old Town [](https://www.expedia.ca/Phoenix-Hotels-Sentral-Old-Town.h81214699.Hotel-Information) Downtown Scottsdale 8.6/10 Excellent (504) "It was lovely and conveniently located. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Evelyn CA $174 CA $238 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Phoenix-Hotels-Sentral-Old-Town.h81214699.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/119000000/118870000/118863700/118863630/7d541b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Yoga](https://images.trvl-media.com/lodging/119000000/118870000/118863700/118863630/e2cf3ce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/119000000/118870000/118863700/118863630/fc448097.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/119000000/118870000/118863700/118863630/56565383.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Sol Modern [](https://www.expedia.ca/Phoenix-Hotels-Sentral-Sol-Modern.h118863630.Hotel-Information) Downtown Phoenix 9.4/10 Exceptional (111) "Great place to stay will be back! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keah CA $172 CA $229 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Phoenix-Hotels-Sentral-Sol-Modern.h118863630.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111350000/111347600/111347508/21e1351b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111350000/111347600/111347508/9dfc0e43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/112000000/111350000/111347600/111347508/344ba91a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/112000000/111350000/111347600/111347508/f7702051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Alloy Midtown [](https://www.expedia.ca/Alloy-Midtown.h111347508.Hotel-Information) Encanto 9.2/10 Wonderful (97) "Beautiful will stay again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $151 CA $210 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Alloy-Midtown.h111347508.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27®ionId=553248635976008216&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Clinic-Phoenix-Hotels-Highgate-Independent.0-n553248635976008216-0--bHighgateIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Clinic-Phoenix-Hotels-Highgate-Independent.0-n553248635976008216-0--bHighgateIndependent.Travel-Guide-Filter-Hotels) ## Top Mayo Clinic Hotel Reviews ![Radisson Hotel Phoenix Airport](https://images.trvl-media.com/lodging/1000000/20000/17400/17364/517fbcac_y.jpg) ### Radisson Hotel Phoenix Airport 10/10 Excellent "Nice clean rooms and great customer service from all staff. The facility is a little olde but well maintained." [](https://expedia.ca/Phoenix-Hotels-Radisson-Hotel-Phoenix-Airport.h17364.Hotel-Information) ![SureStay Hotel by Best Western Phoenix Airport](https://images.trvl-media.com/lodging/1000000/880000/874200/874177/0b333feb_y.jpg) ### SureStay Hotel by Best Western Phoenix Airport 10/10 Excellent "Property was immaculate. Basic to be sure - perfect in all areas for a short layover/buiness stay." [](https://expedia.ca/Phoenix-Hotels-SureStay-Hotel-By-Best-Western-Phoenix-Airport.h874177.Hotel-Information) ![Hilton Garden Inn Phoenix Airport North](https://images.trvl-media.com/lodging/3000000/2260000/2258100/2258085/2eec66b2_y.jpg) ### Hilton Garden Inn Phoenix Airport North 10/10 Excellent "Nice hotel. Clean room. " [](https://expedia.ca/Phoenix-Hotels-Hilton-Garden-Inn-Phoenix-Airport-North.h2258085.Hotel-Information) ![Scottsdale Camelback Resort](https://images.trvl-media.com/lodging/2000000/1190000/1184200/1184132/1a65e3f9_y.jpg) ### Scottsdale Camelback Resort 10/10 Excellent "It was excellent" [](https://expedia.ca/Phoenix-Hotels-Scottsdale-Camelback-Resort.h1184132.Hotel-Information) ![Crowne Plaza Phoenix Airport - PHX by IHG](https://images.trvl-media.com/lodging/1000000/10000/6000/5903/5fc32fb8_y.jpg) ### Crowne Plaza Phoenix Airport - PHX by IHG 10/10 Excellent "Staff was amazing from start to finish. Bar had a great menu. Location was perfect near the airport. " [](https://expedia.ca/Phoenix-Hotels-Crowne-Plaza-Phoenix-Phx-Airport.h5903.Hotel-Information) ![FOUNDRE Phoenix](https://images.trvl-media.com/lodging/1000000/10000/7300/7250/10fc2bd0_y.jpg) ### FOUNDRE Phoenix 10/10 Excellent "Great room location to restraunts and public transportation " [](https://expedia.ca/Phoenix-Hotels-FOUNDRE-Phoenix.h7250.Hotel-Information) ![Talking Stick Resort](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/c132d841_y.jpg) ### Talking Stick Resort 10/10 Excellent "Beautiful bustling casino resort with Tranquil, clean well appointed rooms and comfortable beds. I enjoyed the rains shower-style shower and nice separate deep bathtub. The 24 hr gym and 24hr main pool and Hottubs were excellent. The rate and resort fee were very reasonable and water and coffee/tea in the rooms came included in that. I had a lovely stay Next time I hope I am able to stay longer!" [](https://expedia.ca/Phoenix-Hotels-Talking-Stick-Resort.h3374607.Hotel-Information) ![Marriott Phoenix Resort Tempe at The Buttes](https://images.trvl-media.com/lodging/1000000/90000/82800/82743/60dc5918_y.jpg) ### Marriott Phoenix Resort Tempe at The Buttes 10/10 Excellent "It was fine. " [](https://expedia.ca/Phoenix-Hotels-Marriott-Phoenix-Resort-Tempe-At-The-Buttes.h82743.Hotel-Information) ![Hotel Valley Ho](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/dfaa8e35_y.jpg) ### Hotel Valley Ho 10/10 Excellent "I highly recommend Hotel Valley Ho for a Scottsdale experience. The Valley Ho staff is very friendly and the place is relaxed an festive... and the hotel is centrally located to all of Old Town Scottsdale. Zuzu Restarant in the hotel is a great hangout. One area that is not an option is the outdoor pool in not heated - so during the winter the pool is sometimes closed or you'll have to swim in cold water. The good news is the jacuzzis are heated. Great all round place..." [](https://expedia.ca/Phoenix-Hotels-Hotel-Valley-Ho.h15298.Hotel-Information) ## Find out more about Mayo Clinic ## Mayo Clinic Hotels Guide Expedia.ca offers a selection of 13020 hotels in Mayo Clinic. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Mayo Clinic. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Mayo Clinic neighborhood you prefer. Go ahead. 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