Title: Book the Best CHEAP Hotels in Mayo Clinic, Phoenix from CA $118 - Mayo Clinic Cheap Hotels | Expedia.ca [Vacation Rentals in Phoenix](https://expedia.ca/Phoenix-Vacation-Rentals.d178298.Travel-Guide-VacationRentals)[Flights to Phoenix](https://expedia.ca/Cheap-Flights-To-Phoenix.d178298.Travel-Guide-Flights)[Things to do in Phoenix](https://expedia.ca/Things-To-Do-In-Phoenix.d178298.Travel-Guide-Activities)[Mayo Clinic Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-Clinic.d553248635976008216.Car-Rental-Guide)[Mayo Clinic Vacations](https://expedia.ca/Mayo-Clinic.d553248635976008216.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/budget.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Cheap Hotels in Mayo Clinic, Phoenix from CA $118 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mayo Clinic Cheap Hotels Tonight [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property) Tomorrow [Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-12-28&endDate=2025-12-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property) ## Our top choices for Mayo Clinic cheap hotels ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/3d96914a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/a321f9f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/413774ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed with Sofa bed (One Bedroom) | Living area](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/f2d46939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta Select Scottsdale at Mayo Clinic Campus [](https://www.expedia.ca/Phoenix-Hotels-Sonesta-Select-Scottsdale-At-Mayo-Clinic-Campus.h9767.Hotel-Information) Central Scottsdale 8.2/10 Very good (1065) "Beautiful room, couteous and experienced front desk staff. Easiest check in." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) April CA $144 CA $164 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Phoenix-Hotels-Sonesta-Select-Scottsdale-At-Mayo-Clinic-Campus.h9767.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/w4000h2664x0y0-9226bc87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/f46d1810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Mountain View](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/5e40c1c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, alfresco dining, open daily](https://images.trvl-media.com/lodging/61000000/60260000/60258800/60258737/dfea38c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Tempe [](https://www.expedia.ca/Phoenix-Hotels-The-Westin-Tempe.h60258737.Hotel-Information) Downtown Tempe 9.4/10 Exceptional (1003) "Customer Service was outstanding. The room was spotless with a wonderful view. The shower was amazing." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Silvina CA $141 CA $204 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Phoenix-Hotels-The-Westin-Tempe.h60258737.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/34000000/33740000/33733600/33733512/0a13496f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/34000000/33740000/33733600/33733512/8d2411c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/34000000/33740000/33733600/33733512/94c7ae9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/34000000/33740000/33733600/33733512/35ca3a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Phoenix - Airport North by IHG [](https://www.expedia.ca/Phoenix-Hotels-Holiday-Inn-Express-Suites-Phoenix-Airport-North.h33733512.Hotel-Information) Camelback East 9.4/10 Exceptional (2156) "Nice room, great breakfast and great price!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $127 CA $144 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Phoenix-Hotels-Holiday-Inn-Express-Suites-Phoenix-Airport-North.h33733512.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/3000000/2320000/2314700/2314660/9af52192.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/3000000/2320000/2314700/2314660/13d42465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2320000/2314700/2314660/3b4a4c0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2320000/2314700/2314660/b1dc1654.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Phoenix/Mesa [](https://www.expedia.ca/Phoenix-Hotels-Hyatt-Place-PhoenixMesa.h2314660.Hotel-Information) Mesa Grande 9.2/10 Wonderful (1698) "Cleanliness, location, comfortable bed, decent & delicious free breakfast & friendly staff. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jasmin CA $149 CA $170 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Phoenix-Hotels-Hyatt-Place-PhoenixMesa.h2314660.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2260000/2258100/2258085/2eec66b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/3000000/2260000/2258100/2258085/4c8fc0c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2260000/2258100/2258085/7da9b8cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2260000/2258100/2258085/e9026866.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Phoenix Airport North [](https://www.expedia.ca/Phoenix-Hotels-Hilton-Garden-Inn-Phoenix-Airport-North.h2258085.Hotel-Information) Downtown Phoenix 8.6/10 Excellent (2338) "Easy check in and overall stay was nice and comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $133 CA $151 total includes taxes & fees Dec 31 - Jan 1, 2026 [](https://www.expedia.ca/Phoenix-Hotels-Hilton-Garden-Inn-Phoenix-Airport-North.h2258085.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11114/4bbd3cfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/11200/11114/4f712d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/11200/11114/64b618f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11200/11114/445875a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Phoenix Airport [](https://www.expedia.ca/Phoenix-Hotels-Drury-Inn-Suites-Phoenix-Airport.h11114.Hotel-Information) South Mountain 9.6/10 Exceptional (2320) "It was a great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicholas CA $139 CA $158 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Phoenix-Hotels-Drury-Inn-Suites-Phoenix-Airport.h11114.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2390/f76d2ed6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/2400/2390/c32fe492.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2390/4838ba94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2400/2390/684614cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Tempe/Phoenix Airport, AZ [](https://www.expedia.ca/Phoenix-Hotels-Hampton-Inn-Suites-TempePhoenix-Airport.h2390.Hotel-Information) Double Butte 9.2/10 Wonderful (1005) "Room was cleaned and smelled good, Gabriela checked us in was extremely pleasant. Staff in the breakfast room very nice and helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yolanda CA $114 CA $130 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Phoenix-Hotels-Hampton-Inn-Suites-TempePhoenix-Airport.h2390.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27300/27223/e55ba2ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/30000/27300/27223/9b793e18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/27300/27223/7c5d1835.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/27300/27223/8c784cdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Phoenix Airport, AZ [](https://www.expedia.ca/Phoenix-Hotels-Country-Inn-Suites-By-Radisson.h27223.Hotel-Information) South Mountain 8.2/10 Very good (2901) "Everything about the place was exceptional - especially the front desk efficiency!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $104 CA $118 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Phoenix-Hotels-Country-Inn-Suites-By-Radisson.h27223.Hotel-Information) ![Room, 1 King Bed, Non Smoking, Pool View](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/3450908d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/cde201c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/6a36de96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/30000/26000/25957/142012c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Phoenix Airport [](https://www.expedia.ca/Phoenix-Hotels-Hilton-Phoenix-Airport.h25957.Hotel-Information) South Mountain 8.8/10 Excellent (1077) "Overall very good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $156 CA $176 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Phoenix-Hotels-Hilton-Phoenix-Airport.h25957.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/1000000/90000/84800/84750/d40464a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84800/84750/ec842895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/90000/84800/84750/a1dc1969.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, Pool View (1King Bed)](https://images.trvl-media.com/lodging/1000000/90000/84800/84750/f747ca46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Mesa Superstition Springs [](https://www.expedia.ca/Phoenix-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Mesa-Superstition-Springs.h84750.Hotel-Information) East Mesa 8.2/10 Very good (1797) "I’ve stayed here multiple times and it’s always a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) dean CA $129 CA $147 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Phoenix-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Mesa-Superstition-Springs.h84750.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-10&endDate=2026-01-11®ionId=553248635976008216&adults=2&sort=BUDGET&openPlayBack=true) ## Top Mayo Clinic Hotel Reviews ![Talking Stick Resort](https://images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/c132d841_y.jpg) ### Talking Stick Resort 10/10 Excellent "Yes the room was spotless!" [](https://expedia.ca/Phoenix-Hotels-Talking-Stick-Resort.h3374607.Hotel-Information) ![Arizona Biltmore, LXR Hotels & Resorts](https://images.trvl-media.com/lodging/1000000/10000/9800/9796/e16a0f80_y.jpg) ### Arizona Biltmore, LXR Hotels & Resorts 10/10 Excellent "My trip to the Biltmore was one for the books to hope I can repeat it again in the near future. Outstanding service every amenity you could look for in a hotel was met with a smile! Gorgeous property excellent customer service what more could you need or want it is there. Thank you for a wonderful trip with many happy returns!!! " [](https://expedia.ca/Phoenix-Hotels-Arizona-Biltmore.h9796.Hotel-Information) ![Scottsdale Plaza Resort](https://images.trvl-media.com/lodging/1000000/10000/300/240/ee098133_y.jpg) ### Scottsdale Plaza Resort 10/10 Excellent "Great place, transitioning to a new brand " [](https://expedia.ca/Phoenix-Hotels-Scottsdale-Plaza-Resort.h240.Hotel-Information) ![Hotel Valley Ho](https://images.trvl-media.com/lodging/1000000/20000/15300/15298/dfaa8e35_y.jpg) ### Hotel Valley Ho 10/10 Excellent "Room was great and staff was excellent! " [](https://expedia.ca/Phoenix-Hotels-Hotel-Valley-Ho.h15298.Hotel-Information) ![Hilton Vacation Club Scottsdale Links Resort](https://images.trvl-media.com/lodging/1000000/670000/665200/665144/562f098c_y.jpg) ### Hilton Vacation Club Scottsdale Links Resort 10/10 Excellent "Pool was great. Great location " [](https://expedia.ca/Phoenix-Hotels-Scottsdale-Links-Resort-By-Diamond-Resorts.h665144.Hotel-Information) ![SureStay Hotel by Best Western Phoenix Airport](https://images.trvl-media.com/lodging/1000000/880000/874200/874177/0b333feb_y.jpg) ### SureStay Hotel by Best Western Phoenix Airport 10/10 Excellent "it was ok" [](https://expedia.ca/Phoenix-Hotels-SureStay-Hotel-By-Best-Western-Phoenix-Airport.h874177.Hotel-Information) ![Hilton Garden Inn Phoenix Airport North](https://images.trvl-media.com/lodging/3000000/2260000/2258100/2258085/2eec66b2_y.jpg) ### Hilton Garden Inn Phoenix Airport North 10/10 Excellent "Easy check in and beautiful large room " [](https://expedia.ca/Phoenix-Hotels-Hilton-Garden-Inn-Phoenix-Airport-North.h2258085.Hotel-Information) ![Hilton Phoenix Tapatio Cliffs Resort](https://images.trvl-media.com/lodging/1000000/10000/2800/2736/2d7f14b6_y.jpg) ### Hilton Phoenix Tapatio Cliffs Resort 10/10 Excellent "Staff was amazing and accommodating Emily was such a sweet server top tier in paying attention to details " [](https://expedia.ca/Phoenix-Hotels-Pointe-Hilton-Tapatio-Cliffs-Resort.h2736.Hotel-Information) ![Radisson Hotel Phoenix Airport](https://images.trvl-media.com/lodging/1000000/20000/17400/17364/517fbcac_y.jpg) ### Radisson Hotel Phoenix Airport 10/10 Excellent "The staff was very nice. " [](https://expedia.ca/Phoenix-Hotels-Radisson-Hotel-Phoenix-Airport.h17364.Hotel-Information) ## Frequently asked questions ### What is Mayo Clinic like for travelers on a budget? ### What is there to see and do in Mayo Clinic? ### How can I get to Mayo Clinic and get around on a budget? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Adults Only Resorts & in Central Scottsdale ](https://www.expedia.ca/Central-Scottsdale-Phoenix-Hotels-Adults-Only-Resorts.0-n553248635976007832-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Central Scottsdale ](https://www.expedia.ca/Central-Scottsdale-Phoenix-Hotels-Boutique-Hotel.0-n553248635976007832-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in Central Scottsdale ](https://www.expedia.ca/Central-Scottsdale-Phoenix-Hotels-Business-Hotel.0-n553248635976007832-0-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Central Scottsdale ](https://www.expedia.ca/Central-Scottsdale-Phoenix-Hotels-Casino-Hotel.0-n553248635976007832-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - 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