Title: Book the Best CHEAP Hotels in Mayo Clinic, Phoenix from CA $163 - Mayo Clinic Cheap Hotels | Expedia.ca [Vacation Rentals in Phoenix](https://expedia.ca/Phoenix-Vacation-Rentals.d178298.Travel-Guide-VacationRentals)[Flights to Phoenix](https://expedia.ca/Cheap-Flights-To-Phoenix.d178298.Travel-Guide-Flights)[Things to do in Phoenix](https://expedia.ca/Things-To-Do-In-Phoenix.d178298.Travel-Guide-Activities)[Mayo Clinic Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-Clinic.d553248635976008216.Car-Rental-Guide)[Mayo Clinic Vacations](https://expedia.ca/Mayo-Clinic.d553248635976008216.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/budget.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Cheap Hotels in Mayo Clinic, Phoenix from CA $163 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mayo Clinic Cheap Hotels Tonight [Nov 6 - Nov 7](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-06&endDate=2025-11-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property) Tomorrow [Nov 7 - Nov 8](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-07&endDate=2025-11-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976008216&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property) ## Top Mayo Clinic Cheap Hotels ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/3d96914a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed with Sofa bed (One Bedroom) | Living area](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/f2d46939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/cf4c5bee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/9800/9767/413774ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta Select Scottsdale at Mayo Clinic Campus Central Scottsdale 8.2/10 Very good (1040) "Everyone was extremely pleasant and the location was close to many amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $143 CA $163 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Phoenix-Hotels-Sonesta-Select-Scottsdale-At-Mayo-Clinic-Campus.h9767.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-20&endDate=2025-11-21®ionId=553248635976008216&adults=2&travelerType=budget_property&sort=RECOMMENDED&openPlayBack=true) ## Top Mayo Clinic Hotel Reviews ![Omni Scottsdale Resort & Spa at Montelucia](//images.trvl-media.com/lodging/1000000/10000/2300/2263/38914575_y.jpg) ### Omni Scottsdale Resort & Spa at Montelucia 10/10 Excellent "Beautiful property " [](https://expedia.ca/Phoenix-Hotels-Omni-Scottsdale-Resort-Spa-At-Montelucia.h2263.Hotel-Information) ![Hilton Phoenix Tapatio Cliffs Resort](//images.trvl-media.com/lodging/1000000/10000/2800/2736/2d7f14b6_y.jpg) ### Hilton Phoenix Tapatio Cliffs Resort 10/10 Excellent "Great " [](https://expedia.ca/Phoenix-Hotels-Pointe-Hilton-Tapatio-Cliffs-Resort.h2736.Hotel-Information) ![Crowne Plaza Phoenix Airport - PHX by IHG](//images.trvl-media.com/lodging/1000000/10000/6000/5903/5fc32fb8_y.jpg) ### Crowne Plaza Phoenix Airport - PHX by IHG 10/10 Excellent "Great location, so close to the airport, makes traveling so much easier. Very clean location and most staff were amazing" [](https://expedia.ca/Phoenix-Hotels-Crowne-Plaza-Phoenix-Phx-Airport.h5903.Hotel-Information) ![Arizona Biltmore, LXR Hotels & Resorts](//images.trvl-media.com/lodging/1000000/10000/9800/9796/e16a0f80_y.jpg) ### Arizona Biltmore, LXR Hotels & Resorts 10/10 Excellent "Beautiful hotel, friendly staff, " [](https://expedia.ca/Phoenix-Hotels-Arizona-Biltmore.h9796.Hotel-Information) ![Talking Stick Resort](//images.trvl-media.com/lodging/4000000/3380000/3374700/3374607/c132d841_y.jpg) ### Talking Stick Resort 10/10 Excellent "Rooms are great and the staff is definitely above the average. " [](https://expedia.ca/Phoenix-Hotels-Talking-Stick-Resort.h3374607.Hotel-Information) ![Hyatt Regency Phoenix](//images.trvl-media.com/lodging/1000000/10000/6900/6802/4fb94d6b_y.jpg) ### Hyatt Regency Phoenix 10/10 Excellent "Everything was good. " [](https://expedia.ca/Phoenix-Hotels-Hyatt-Regency-Phoenix.h6802.Hotel-Information) ![Hilton Garden Inn Phoenix Airport North](//images.trvl-media.com/lodging/3000000/2260000/2258100/2258085/2eec66b2_y.jpg) ### Hilton Garden Inn Phoenix Airport North 10/10 Excellent "Great airport shuttle service and great front desk service I’ll definitely stay here again" [](https://expedia.ca/Phoenix-Hotels-Hilton-Garden-Inn-Phoenix-Airport-North.h2258085.Hotel-Information) ![SureStay Hotel by Best Western Phoenix Airport](//images.trvl-media.com/lodging/1000000/880000/874200/874177/0b333feb_y.jpg) ### SureStay Hotel by Best Western Phoenix Airport 10/10 Excellent "Clean and safe room, shuttle to the airport. Exceptional service! " [](https://expedia.ca/Phoenix-Hotels-SureStay-Hotel-By-Best-Western-Phoenix-Airport.h874177.Hotel-Information) ![Days Inn & Suites by Wyndham Mesa Near Phoenix](//images.trvl-media.com/lodging/1000000/10000/3800/3749/7b43a1e5_y.jpg) ### Days Inn & Suites by Wyndham Mesa Near Phoenix 10/10 Excellent "Yes" [](https://expedia.ca/Phoenix-Hotels-Days-Hotel-By-Wyndham-Mesa-Near-Phoenix.h3749.Hotel-Information) ## Frequently asked questions ### What is Mayo Clinic like for travelers on a budget? > Check out low cost places to stay in Mayo Clinic on Expedia.com and plan a trip that matches your budget. You can scroll through a variety of accommodations with Member Prices to find great deals. With our site's convenient page filters, you can limit results by your price range, or by favorite amenities like free breakfast and a swimming pool. Or, narrow down your search with the location filters to see reasonable options close to local sights. As you browse, use the heart button to save your favorites so that you can find them later when you're ready to book. Need a car or a flight too? Take your pick of the travel packages offered under Bundle and Save and discover huge discounts when you reserve your transportation at the same time. ### What is there to see and do in Mayo Clinic? > You don't need to spend big to find things to see and do in Mayo Clinic. You can budget for the top local attractions that interest you most, such as Talking Stick Resort Casino, and then look for sights and activities that cost little or nothing at all. Take in the local culture at Western Spirit: Scottsdale's Museum of the West and Casino Arizona, or enjoy the area's natural beauty at Camelback Mountain. ### How can I get to Mayo Clinic and get around on a budget? > Checking out these ways to get around Mayo Clinic is a smart way to keep your trip affordable. The nearest airport is 9.8 mi (15.7 km) away from the center in Mesa, AZ (MSC-Falcon Field Municipal). If that doesn't suit your budget, you can book a flight to Phoenix Sky Harbor Intl. Airport (PHX), located 16.3 mi (26.3 km) away. 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[Flights from Toronto (YYZ) to Phoenix (PHX)](https://www.expedia.ca/lp/flights/yyz/phx/toronto-to-phoenix) - [Mayo Clinic Scottsdale](https://www.expedia.ca/Mayo-Clinic-Scottsdale-Central-Scottsdale.d6131819.Vacation-Attraction) - [Visit Mirage Mountain](https://www.expedia.ca/Phoenix-Mirage-Mountain.dx553248635976473432) - [Visit Mountainside Plaza](https://www.expedia.ca/Phoenix-Mountainside-Plaza.dx553248635976480453) - [Book Hotels in Mayo Clinic on Expedia.com](https://www.expedia.com/Mayo-Clinic-Phoenix-Hotels-Cheap-Hotels.0-n553248635976008216-0-tCheapHotels.Travel-Guide-Filter-Hotels)