Title: Hotels by Independent in Matlacha Isles-Matlacha Shores from CA $90 | Expedia.ca [Matlacha Isles-Matlacha Shores Travel Guide](https://expedia.ca/Matlacha-Isles-Matlacha-Shores.dx553248635975849540)[Hotels in Matlacha Isles-Matlacha Shores](https://expedia.ca/Matlacha-Isles-Matlacha-Shores-Hotels.d553248635975849540.Travel-Guide-Hotels)[Vacation Rentals in Matlacha Isles-Matlacha Shores](https://expedia.ca/Matlacha-Isles-Matlacha-Shores-Vacation-Rentals.d553248635975849540.Travel-Guide-VacationRentals)[Flights to Matlacha Isles-Matlacha Shores](https://expedia.ca/Cheap-Flights-To-Matlacha-Isles-Matlacha-Shores.d553248635975849540.Travel-Guide-Flights)[Things to do in Matlacha Isles-Matlacha Shores](https://expedia.ca/Things-To-Do-In-Matlacha-Isles-Matlacha-Shores.d553248635975849540.Travel-Guide-Activities)[Matlacha Isles-Matlacha Shores Car Rentals](https://expedia.ca/Car-Rentals-In-Matlacha-Isles-Matlacha-Shores.d553248635975849540.Car-Rental-Guide)[Matlacha Isles-Matlacha Shores Vacation Packages](https://expedia.ca/Matlacha-Isles-Matlacha-Shores.d553248635975849540.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Independent in Matlacha Isles-Matlacha Shores from CA $90 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=553248635975849540&startDate=2025-09-24&endDate=2025-09-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975849540&startDate=2025-09-25&endDate=2025-09-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248635975849540&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635975849540&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Matlacha Isles-Matlacha Shores Independent Hotels ## Our top choices for Matlacha Isles-Matlacha Shores Independent ![Exterior](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast served](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/abf6da91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/0153ec95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/1051a5d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Beach Resort Fort Myers Fort Myers Beach 9.0/10 Wonderful (1492) "Great stay, accommodations, location" CA $198 CA $275 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Suite with King Bed, Beachfront, Balcony | Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/767ba460.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/1808ce0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite with Two Doubles, Beachfront, Balcony](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/2e8856cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort Fort Myers Beach 8.8/10 Excellent (1048) "All around great place to stay. " CA $132 CA $179 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/dd6ccde3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/82b672d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/167b1a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pink Shell Beach Resort and Marina Fort Myers Beach 9.4/10 Exceptional (1068) "Staff was very friendly , amenities were excellent" CA $245 CA $365 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Offshore King Suite(Family Friendly, Not Pet Friendly)](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/a8b337e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 2 Double Beds | Private kitchen](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/b9cbc2ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 1 Queen Bed, Canal View | View from room](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w1978h1500x461y0-e23a57cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lighthouse Resort Inn & Suites Fort Myers Beach 8.6/10 Excellent (1507) "The staff was very friendly and helpful. " CA $138 CA $182 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Apartment, Multiple Beds, Partial Ocean View | Beach/ocean view](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/fb0b7d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/ee4ac5cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/b348cef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 Queen Bed, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/96081da3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Edison Beach House Fort Myers Beach 9.4/10 Exceptional (1502) "Right on the beach and there are several shops and restaurants/bars with in close walking distance! " CA $177 CA $198 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Edison-Beach-House.h11753200.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/faba246e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/cda8d432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/1b9c29fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/23e15eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dolphin Key Resort Caloosahatchee 8.8/10 Excellent (1178) "Excellent location " CA $131 CA $147 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Dolphin-Key-Resort.h1632691.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/a5c54d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/a7398ba1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dock](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/24a52d40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, kayaking, fishing](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/560da633.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tween Waters Island Resort & Spa Captiva 8.6/10 Excellent (1005) "We had an amazing stay at the Captiva Island! The place is great, the service was excellent. We truly enjoyed every moment and will definitely come back again. Highly recommended!" CA $198 CA $270 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Fort-Myers-Hotels-Tween-Waters-Island-Resort-Spa.h170769.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/0be36f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/08b639cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/693ea816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/98f0aac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Allure Suites McGregor 7.6/10 Good (1004) "I like my stays here. Super quiet. Rooms are big. Nice pool & heated hot tub. " CA $88 CA $99 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/19000000/18120000/18111200/18111123/5232bbaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Single Room, 1 King Bed](https://images.trvl-media.com/lodging/19000000/18120000/18111200/18111123/4c7e1b1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, River View](https://images.trvl-media.com/lodging/19000000/18120000/18111200/18111123/1723efbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/19000000/18120000/18111200/18111123/9c590979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riverview Inn Hancock 7.6/10 Good (597) "A nice and quiet place to stay for the weekend " CA $80 CA $90 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Riverview-Inn.h18111123.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/6c1090cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/0f55ab5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/925dd3c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/09cc3103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Inn Sanibel 9.0/10 Wonderful (1002) "Very beautiful and just a very short walk to the beach " CA $355 CA $476 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Inn.h40711.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-08&endDate=2025-10-09®ionId=553248635975849540&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMatlacha-Isles-Matlacha-Shores-Hotels-Independent.0-0-d553248635975849540--bIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMatlacha-Isles-Matlacha-Shores-Hotels-Independent.0-0-d553248635975849540--bIndependent.Travel-Guide-Filter-Hotels) ## Top Matlacha Isles-Matlacha Shores Hotel Reviews ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](//images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "I found our room clean and very comfortable. Enjoyed the balcony in the evenings. Breakfast was great! Everyone was very friendly." [](https://expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park](//images.trvl-media.com/lodging/1000000/800000/798500/798422/16c0566c_y.jpg) ### Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park 10/10 Excellent "Good." [](https://expedia.ca/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) ![The Lighthouse Resort Inn & Suites](//images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3_y.jpg) ### The Lighthouse Resort Inn & Suites 10/10 Excellent "The room was excellent. It was very comfortable. We were glad that on a Thursday night the loud music in the bar stopped at 10pm." [](https://expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![DiamondHead Beach Resort](//images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "We had an amazing stay at DiamondHead Beach Resort! Our beachfront room overlooked the Gulf, and the views were absolutely stunning. We barely left the resort because everything we needed was right there—beautiful beach access, a great pool area, and delicious food and drinks. The staff was equally amazing, always friendly and attentive, which made our stay even more enjoyable. It was the perfect relaxing getaway, and we can’t wait to come back" [](https://expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Sanibel Island Beach Resort](//images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Quick trip to relax. Perfect location right on the beach! Several different room views available- I would choose beach view next time but my room was just perfect. Mid week was nice and quiet, really was just what I needed!" [](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Lani Kai Beachfront Resort](//images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "The area is still recovering from hurricane Ian. Most places are still rebuilding. Lani Kai has come along way still has the fantastic beach nice rooms good food can't wait until the roof top bar and restaurant opens their getting close. Hopefully on our next stay. Our get-away " [](https://expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Margaritaville Beach Resort Fort Myers ](//images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574_y.jpg) ### Margaritaville Beach Resort Fort Myers 10/10 Excellent "Great stay, accommodations, location" [](https://expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Marriott Sanibel Harbour Resort & Spa](//images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07_y.jpg) ### Marriott Sanibel Harbour Resort & Spa 10/10 Excellent "Wonderful " [](https://expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Edison Beach House](//images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/fb0b7d7c_y.jpg) ### Edison Beach House 10/10 Excellent "I loved that it was a studio like apt. that was fully stocked with all of the kitchen supplies. We were able to go grocery shopping and didn't have to eat out all of the time. 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