The safe clean Hotel with very nice staff is mid way between Palazzo Ducale, and Palazzo Te, the main sights. Its just 10 mins. Walk to either.
The décor is a little tired, but, the Hotel is in good shape.
Piazza Erbe, with an outdoor market Thursdays and great restaurants, is 5 minutes walk through the pedestrian only cobbled streets and old town. Mantova is a gem.