Title: Hotels by La Quinta Inn & Suites in Main Street Fort Pierce from CA $153 | Expedia.ca [Main Street Fort Pierce Travel Guide](https://expedia.ca/Fort-Pierce-Main-Street-Fort-Pierce.dx6348251)[Vacation Rentals in Fort Pierce](https://expedia.ca/Fort-Pierce-Vacation-Rentals.d7301.Travel-Guide-VacationRentals)[Flights to Fort Pierce](https://expedia.ca/Cheap-Flights-To-Fort-Pierce.d7301.Travel-Guide-Flights)[Things to do in Fort Pierce](https://expedia.ca/Things-To-Do-In-Fort-Pierce.d7301.Travel-Guide-Activities)[Main Street Fort Pierce Car Rentals](https://expedia.ca/Car-Rentals-In-Main-Street-Fort-Pierce.d6348251.Car-Rental-Guide)[Main Street Fort Pierce Vacations](https://expedia.ca/Main-Street-Fort-Pierce.d6348251.Destination-Travel-Guides) ![The local area walk around](https://images.trvl-media.com/place/7301/735dc485-4eb5-4f9c-9c52-7e981b1d3d4a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Karen Rinaldo-green # Find Hotels by La Quinta Inn & Suites in Main Street Fort Pierce from CA $153 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6348251&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=6348251&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6348251&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6348251&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Main Street Fort Pierce La Quinta Inn & Suites ![Lobby](https://images.trvl-media.com/lodging/3000000/2180000/2171100/2171072/034ef695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/3000000/2180000/2171100/2171072/909041a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2180000/2171100/2171072/94f9650f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2180000/2171100/2171072/a1dee77d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Ft. Pierce [](https://www.expedia.ca/Vero-Beach-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Ft-Pierce.h2171072.Hotel-Information) Fort Pierce 8.0/10 Very good (1002) "My stay was great, very happy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $137 CA $153 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Vero-Beach-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Ft-Pierce.h2171072.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-27&endDate=2025-12-28®ionId=6348251&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMain-Street-Fort-Pierce-Fort-Pierce-Hotels-La-Quinta-Inn-Suites.0-n6348251-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMain-Street-Fort-Pierce-Fort-Pierce-Hotels-La-Quinta-Inn-Suites.0-n6348251-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Main Street Fort Pierce Hotel Reviews ![SpringHill Suites Port St. Lucie](https://images.trvl-media.com/lodging/1000000/110000/102000/101904/79ea3410_y.jpg) ### SpringHill Suites Port St. Lucie 10/10 Excellent "Room was spotless!!!" [](https://expedia.ca/Vero-Beach-Hotels-SpringHill-Suites-Port-St-Lucie.h101904.Hotel-Information) ![Hampton Inn & Suites Stuart-North](https://images.trvl-media.com/lodging/3000000/2220000/2212000/2211950/76e06ec5_y.jpg) ### Hampton Inn & Suites Stuart-North 10/10 Excellent "Clean room. Friendly front desk. Conveniently located. Liked the room layout." [](https://expedia.ca/Vero-Beach-Hotels-Hampton-Inn-Suites-Stuart-North.h2211950.Hotel-Information) ![Ocean Breeze Inn Vero Beach](https://images.trvl-media.com/lodging/1000000/10000/9900/9857/w5909h3977x0y0-d287f041_y.jpg) ### Ocean Breeze Inn Vero Beach 10/10 Excellent " Great" [](https://expedia.ca/Vero-Beach-Hotels-Ocean-Breeze-Inn-Vero-Beach.h9857.Hotel-Information) ![Tru by Hilton Port St. Lucie Tradition](https://images.trvl-media.com/lodging/79000000/78120000/78119400/78119323/970bffa0_y.jpg) ### Tru by Hilton Port St. Lucie Tradition 10/10 Excellent "Best check in ever. Super friendly staff and very quick and helpful. " [](https://expedia.ca/Port-Saint-Lucie-Hotels-Tru-By-Hilton-Port-St-Lucie.h78119323.Hotel-Information) ![Hampton Inn Vero Beach](https://images.trvl-media.com/lodging/1000000/70000/64200/64119/21fd2b08_y.jpg) ### Hampton Inn Vero Beach 10/10 Excellent "Property was well maintained. The checkin was fast and efficient. The room was clean. The bed was clean andcomfortable " [](https://expedia.ca/Vero-Beach-Hotels-Hampton-Inn-Vero-Beach.h64119.Hotel-Information) ![Motel 6 Ft. Pierce, FL, Fort Pierce](https://images.trvl-media.com/lodging/1000000/1000000/996200/996179/7067c305_y.jpg) ### Motel 6 Ft. Pierce, FL, Fort Pierce 10/10 Excellent "The charger ports not working to charge our phone spoke to management nothing was done the toilet kept getting clogged up I was annoyed and still is I’m doing extended stay " [](https://expedia.ca/Vero-Beach-Hotels-Motel-6-Ft-Pierce.h996179.Hotel-Information) ![Marriott Hutchinson Island Beach Resort, Golf & Marina](https://images.trvl-media.com/lodging/1000000/20000/11900/11892/4093d97c_y.jpg) ### Marriott Hutchinson Island Beach Resort, Golf & Marina 10/10 Excellent "." [](https://expedia.ca/Vero-Beach-Hotels-Marriott-Hutchinson-Island-Beach-Resort.h11892.Hotel-Information) ![Hampton Inn & Suites Port St. Lucie, West](https://images.trvl-media.com/lodging/1000000/870000/860400/860330/7d0a569c_y.jpg) ### Hampton Inn & Suites Port St. Lucie, West 10/10 Excellent "Clean room. Staff" [](https://expedia.ca/Vero-Beach-Hotels-Hampton-Inn-Suites-Port-St-Lucie.h860330.Hotel-Information) ![Costa d'Este Beach Resort and Spa](https://images.trvl-media.com/lodging/1000000/20000/18100/18083/8e326e5e_y.jpg) ### Costa d'Este Beach Resort and Spa 10/10 Excellent "Great vibe and location" [](https://expedia.ca/Vero-Beach-Hotels-Costa-DEste-Beach-Resort-And-Spa.h18083.Hotel-Information) ## Find out more about Main Street Fort Pierce ## Main Street Fort Pierce Hotels Guide Expedia.ca offers a selection of 2924 hotels in Main Street Fort Pierce. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Main Street Fort Pierce. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Main Street Fort Pierce neighborhood you prefer. Go ahead. 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