Title: Hotels by Best Western in Main Street Fort Pierce from CA $149 | Expedia.ca [Main Street Fort Pierce Travel Guide](https://expedia.ca/Fort-Pierce-Main-Street-Fort-Pierce.dx6348251)[Vacation Rentals in Fort Pierce](https://expedia.ca/Fort-Pierce-Vacation-Rentals.d7301.Travel-Guide-VacationRentals)[Flights to Fort Pierce](https://expedia.ca/Cheap-Flights-To-Fort-Pierce.d7301.Travel-Guide-Flights)[Things to do in Fort Pierce](https://expedia.ca/Things-To-Do-In-Fort-Pierce.d7301.Travel-Guide-Activities)[Main Street Fort Pierce Car Rentals](https://expedia.ca/Car-Rentals-In-Main-Street-Fort-Pierce.d6348251.Car-Rental-Guide)[Main Street Fort Pierce Vacations](https://expedia.ca/Main-Street-Fort-Pierce.d6348251.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/45c14394f00e719edfc1f89173e8934f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Best Western in Main Street Fort Pierce from CA $149 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=6348251&startDate=2025-10-29&endDate=2025-10-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6348251&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6348251&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6348251&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Main Street Fort Pierce Best Western Hotels ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/20000/19950/8c515b21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/20000/19950/9a9017db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/20000/19950/690a5156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/20000/19950/cd5eaf3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Downtown Stuart Stuart 8.6/10 Excellent (1000) "All was good for the time was there, and front desk staff were great, bed was good and breakfast was decent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $150 CA $168 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Vero-Beach-Hotels-Best-Western-Downtown-Stuart.h19950.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/0302e69f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/1c11919b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/fbeafdb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/f818595e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Port St. Lucie Port Saint Lucie 8.6/10 Excellent (1000) "Clean and great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erica CA $133 CA $149 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Vero-Beach-Hotels-Best-Western-Port-St-Lucie.h13549.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=6348251&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMain-Street-Fort-Pierce-Fort-Pierce-Hotels-Best-Western.0-n6348251-0--bBestWestern.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMain-Street-Fort-Pierce-Fort-Pierce-Hotels-Best-Western.0-n6348251-0--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Main Street Fort Pierce Hotel Reviews ![Holiday Inn Express & Suites Port St. Lucie West by IHG](//images.trvl-media.com/lodging/3000000/2470000/2466900/2466823/d4b9506f_y.jpg) ### Holiday Inn Express & Suites Port St. Lucie West by IHG 10/10 Excellent "Breakfast was really limited " [](https://expedia.ca/Vero-Beach-Hotels-Holiday-Inn-Express-Suites-Port-St-Lucie-West.h2466823.Hotel-Information) ![Best Western Downtown Stuart](//images.trvl-media.com/lodging/1000000/20000/20000/19950/8c515b21_y.jpg) ### Best Western Downtown Stuart 10/10 Excellent "I was really pleased please with so many things about the Best Western Downtown Stuart - including room cleanliness, room air conditioning comfort, quality breakfast! Excellent service my entire 3-night stay!" [](https://expedia.ca/Vero-Beach-Hotels-Best-Western-Downtown-Stuart.h19950.Hotel-Information) ![At Home Inn](//images.trvl-media.com/lodging/8000000/7990000/7980900/7980801/3319119d_y.jpg) ### At Home Inn 10/10 Excellent "Rooms where clean and ac works perfect " [](https://expedia.ca/Vero-Beach-Hotels-At-Home-Inn.h7980801.Hotel-Information) ![The Lucie](//images.trvl-media.com/lodging/1000000/10000/10000/9939/ab6982c4_y.jpg) ### The Lucie 10/10 Excellent "Absolutely stunning resort! Our ocean-view room with a private balcony was the perfect spot to watch the sunrise and unwind to the sound of the waves. Having direct access to the beach made it even more special — just steps from our door to the sand. Everything was serene, clean, and beautifully maintained. Ideal for couples looking for a relaxing, romantic getaway." [](https://expedia.ca/Jensen-Beach-Hotels-The-Lucie.h9939.Hotel-Information) ![Vero Beach Inn & Suites I-95](//images.trvl-media.com/lodging/1000000/10000/100/8/816a36ef_y.jpg) ### Vero Beach Inn & Suites I-95 10/10 Excellent "Good service need to work on the breakfast menu " [](https://expedia.ca/Vero-Beach-Hotels-Vero-Beach-Inn-Suites-I-95.h8.Hotel-Information) ![Hutchinson Island Hotel](//images.trvl-media.com/lodging/1000000/440000/434500/434493/bc1255d0_y.jpg) ### Hutchinson Island Hotel 10/10 Excellent "Staff was extra helpful and friendly, nice little beach of perfect sand with large beach chairs outback. I will stay here again!" [](https://expedia.ca/Vero-Beach-Hotels-Hutchinson-Island-Plaza-Hotel-And-Suites.h434493.Hotel-Information) ![Marriott Hutchinson Island Beach Resort, Golf & Marina](//images.trvl-media.com/lodging/1000000/20000/11900/11892/4093d97c_y.jpg) ### Marriott Hutchinson Island Beach Resort, Golf & Marina 10/10 Excellent "Very nice and quiet " [](https://expedia.ca/Vero-Beach-Hotels-Marriott-Hutchinson-Island-Beach-Resort.h11892.Hotel-Information) ![Fairfield Inn & Suites by Marriott Fort Pierce](//images.trvl-media.com/lodging/3000000/2250000/2244300/2244228/83de94bf_y.jpg) ### Fairfield Inn & Suites by Marriott Fort Pierce 10/10 Excellent "Fantastic all around! " [](https://expedia.ca/Vero-Beach-Hotels-Fairfield-Inn-Suites-By-Marriott-Fort-Pierce.h2244228.Hotel-Information) ![Tru by Hilton Port St. Lucie Tradition](//images.trvl-media.com/lodging/79000000/78120000/78119400/78119323/970bffa0_y.jpg) ### Tru by Hilton Port St. Lucie Tradition 10/10 Excellent "I have never seen a hotel room so roomy! I really enjoyed the extra space so my toddler could rounds around free and safe." [](https://expedia.ca/Port-Saint-Lucie-Hotels-Tru-By-Hilton-Port-St-Lucie.h78119323.Hotel-Information) ## Find out more about Main Street Fort Pierce ## Main Street Fort Pierce Hotels Guide Expedia.ca offers a selection of 2873 hotels in Main Street Fort Pierce. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Main Street Fort Pierce. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Main Street Fort Pierce neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Main Street Fort Pierce, Fort Pierce now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Independent Hotels in Aquarina](https://www.expedia.ca/Aquarina-Melbourne-Beach-Hotels-Independent.0-n553248635976468581-0--bIndependent.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in St. Lucie County](https://www.expedia.ca/Destinations-In-St-Lucie-County-Beach-Hotel.0-0-d553248635083914435-tBeachHotel.Hotel-Filter-Destinations) - [Cheap Hotels in St. Lucie County](https://www.expedia.ca/Destinations-In-St-Lucie-County-Cheap-Hotels.0-0-d553248635083914435-tCheapHotels.Hotel-Filter-Destinations) - [Luxury Hotels in St. Lucie County](https://www.expedia.ca/Destinations-In-St-Lucie-County-Luxury-Hotel.0-0-d553248635083914435-tLuxuryHotel.Hotel-Filter-Destinations) - [Pet-Friendly Hotels in St. Lucie County](https://www.expedia.ca/Destinations-In-St-Lucie-County-Pet-Friendly-Hotel.0-0-d553248635083914435-tPetfriendlyHotel.Hotel-Filter-Destinations) - 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