Title: Hotels by Motel 6 in Main Street | Expedia.ca [Main Street Travel Guide](https://expedia.ca/Ann-Arbor-Main-Street.dx553248633938969669)[Vacation Rentals in Ann Arbor](https://expedia.ca/Ann-Arbor-Vacation-Rentals.d6059241.Travel-Guide-VacationRentals)[Flights to Ann Arbor](https://expedia.ca/Cheap-Flights-To-Ann-Arbor.d6059241.Travel-Guide-Flights)[Things to do in Ann Arbor](https://expedia.ca/Things-To-Do-In-Ann-Arbor.d6059241.Travel-Guide-Activities)[Main Street Car Rentals](https://expedia.ca/Car-Rentals-In-Main-Street.d553248633938969669.Car-Rental-Guide)[Main Street Vacations](https://expedia.ca/Main-Street.d553248633938969669.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Motel 6 in Main Street ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=553248633938969669&startDate=2025-09-28&endDate=2025-09-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=553248633938969669&startDate=2025-09-29&endDate=2025-09-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248633938969669&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248633938969669&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Main Street Motel 6 Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMain-Street-Ann-Arbor-Hotels-Motel-6.0-n553248633938969669-0--bMotel6.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMain-Street-Ann-Arbor-Hotels-Motel-6.0-n553248633938969669-0--bMotel6.Travel-Guide-Filter-Hotels) ## Top Main Street Hotel Reviews ![Comfort Inn & Suites University South](//images.trvl-media.com/lodging/1000000/920000/915500/915500/5c96e5f1_y.jpg) ### Comfort Inn & Suites University South 10/10 Excellent "Currently under renovation, looks nice what has been done so far." [](https://expedia.ca/Ann-Arbor-Hotels-Comfort-Inn-Suites-University-South.h915500.Hotel-Information) ![Saint John's Resort](//images.trvl-media.com/lodging/2000000/1340000/1330400/1330398/8343bf70_y.jpg) ### Saint John's Resort 10/10 Excellent "Beautiful property" [](https://expedia.ca/Detroit-Hotels-The-Inn-At-St-Johns.h1330398.Hotel-Information) ![Ann Arbor Regent Hotel & Suites](//images.trvl-media.com/lodging/1000000/20000/19000/18996/58e15b9b_y.jpg) ### Ann Arbor Regent Hotel & Suites 10/10 Excellent "On top of that the breakfast was amazing" [](https://expedia.ca/Ann-Arbor-Hotels-Ann-Arbor-Regent-Hotel-Suites.h18996.Hotel-Information) ![Hyatt Place Ann Arbor](//images.trvl-media.com/lodging/20000000/19550000/19549500/19549451/178e673b_y.jpg) ### Hyatt Place Ann Arbor 10/10 Excellent "The hotel room was spacious, clean and comfortable. The air conditioning was disappointing as there was no way to keep the running to have constant ventilation. So we either were too cold by keeping the temperature low for constant air flow, or too warn by raising the temperature when we got too cold. Rather disappointing for an otherwise quality hotel" [](https://expedia.ca/Ann-Arbor-Hotels-Hyatt-Place-Ann-Arbor.h19549451.Hotel-Information) ![Wyndham Garden Ann Arbor](//images.trvl-media.com/lodging/1000000/460000/458100/458015/0abd6013_y.jpg) ### Wyndham Garden Ann Arbor 10/10 Excellent "Everything was great" [](https://expedia.ca/Ann-Arbor-Hotels-Wyndham-Garden-Ann-Arbor.h458015.Hotel-Information) ![Graduate by Hilton Ann Arbor](//images.trvl-media.com/lodging/1000000/30000/20200/20172/35526491_y.jpg) ### Graduate by Hilton Ann Arbor 10/10 Excellent "Lovely hotel a few block off the main drag in Ann Arbor and a 10-15 min walk from Kerrytown." [](https://expedia.ca/Ann-Arbor-Hotels-Graduate-Ann-Arbor.h20172.Hotel-Information) ![The Kensington Hotel](//images.trvl-media.com/lodging/1000000/10000/5800/5768/6ad931a7_y.jpg) ### The Kensington Hotel 10/10 Excellent "I stay here often and the staff is very friendly and accommodating every time. It would be nice to have updated rooms though. The decor is tired and old in many of the rooms I have stayed in but rooms are always clean. The Beekman products are really top notch. The restaurant staff were also very helpful and seated me where I could have my breakfast with my dog. I have stayed at other hotels in Ann Arbor and I still prefer to stay at the Kensington." [](https://expedia.ca/Ann-Arbor-Hotels-The-Kensington-Hotel.h5768.Hotel-Information) ![Weber's Hotel & Restaurant](//images.trvl-media.com/lodging/1000000/30000/21600/21561/ef32a41f_y.jpg) ### Weber's Hotel & Restaurant 10/10 Excellent "Comfortable. Helpful and friendly staff. " [](https://expedia.ca/Ann-Arbor-Hotels-Webers-Hotel-Restaurant.h21561.Hotel-Information) ![Homewood Suites by Hilton Ann Arbor](//images.trvl-media.com/lodging/79000000/78080000/78072900/78072889/b0c3a008_y.jpg) ### Homewood Suites by Hilton Ann Arbor 10/10 Excellent "Everything was amazing. Love the room. The breakfast was very good." [](https://expedia.ca/Ann-Arbor-Hotels-Homewood-Suites-By-Hilton-Ann-Arbor.h78072889.Hotel-Information) ## Find out more about Main Street ## Main Street Hotels Guide Expedia.ca offers a selection of 673 hotels in Main Street. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Main Street. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Main Street neighborhood you prefer. Go ahead. 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[Flights from Ann Arbor](https://www.expedia.ca/lp/flights/6059241/flights-from-ann-arbor) - [Ann Arbor Vacations](https://www.expedia.ca/Ann-Arbor.d6059241.Destination-Travel-Guides) - [Visit Ann Arbor](https://www.expedia.ca/Ann-Arbor.dx6059241) - [Budget Rental Cars in Ann Arbor](https://www.expedia.ca/Budget-Car-Rentals-In-Ann-Arbor.d6059241-c39.Car-Rental-Guide-Suppliers) - [Car rental Ann Arbor](https://www.expedia.ca/Car-Rentals-In-Ann-Arbor.d6059241.Car-Rental-Guide) - [Hertz Rental Cars in Ann Arbor](https://www.expedia.ca/Hertz-Car-Rentals-In-Ann-Arbor.d6059241-c40.Car-Rental-Guide-Suppliers) - [Ann Arbor Vacation Rentals](https://www.expedia.ca/Ann-Arbor-Vacation-Rentals.d6059241.Travel-Guide-VacationRentals) - [Things to do in Ann Arbor](https://www.expedia.ca/Things-To-Do-In-Ann-Arbor.d6059241.Travel-Guide-Activities) - [Book Hotels in Main Street on Expedia.com](https://www.expedia.com/Main-Street-Ann-Arbor-Hotels-Motel-6.0-n553248633938969669-0--bMotel6.Travel-Guide-Filter-Hotels)