Title: Book the Best BEACH RESORTS in Lower Matecumbe Key, FL - Lower Matecumbe Key Hotels on the Beach| Expedia.ca [Lower Matecumbe Key Travel Guide](https://expedia.ca/Lower-Matecumbe-Key.dx553248635975749077)[Hotels in Lower Matecumbe Key](https://expedia.ca/Lower-Matecumbe-Key-Hotels.d553248635975749077.Travel-Guide-Hotels)[Vacation Rentals in Lower Matecumbe Key](https://expedia.ca/Lower-Matecumbe-Key-Vacation-Rentals.d553248635975749077.Travel-Guide-VacationRentals)[Flights to Lower Matecumbe Key](https://expedia.ca/Cheap-Flights-To-Lower-Matecumbe-Key.d553248635975749077.Travel-Guide-Flights)[Lower Matecumbe Key Car Rentals](https://expedia.ca/Car-Rentals-In-Lower-Matecumbe-Key.d553248635975749077.Car-Rental-Guide)[Lower Matecumbe Key Vacation Packages](https://expedia.ca/Lower-Matecumbe-Key.d553248635975749077.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/497000/497078-annes-beach.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find beach hotels in Lower Matecumbe Key, FL ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lower Matecumbe Key Beach Hotel Tonight [Oct 28 - Oct 29](https://www.expedia.ca/Hotel-Search?regionId=553248635975749077&startDate=2025-10-28&endDate=2025-10-29&adults=2&amenities=BEACH&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=beach) Tomorrow [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=553248635975749077&startDate=2025-10-29&endDate=2025-10-30&adults=2&amenities=BEACH&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=beach) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975749077&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=BEACH&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=beach) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635975749077&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=BEACH&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=beach) ## Top Lower Matecumbe Key Beach Hotel ## Top Lower Matecumbe Key Hotel Reviews ## Explore a world of travel with Expedia - 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