Los Anastacios Vacation Rentals

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Our top choices for Los Anastacios vacation rentals

Treehouse in Jaramillo

Lucero - Luxury Treehouses
3.5 star property
8.8 out of 10, Excellent, (5 reviews)
"Print or save your map beforehand. Do not exit onto a gravel road! The property is located inside a golf community. The map on the listing is incorrect! As of October 2025 all maps including Google, Waze and Apple maps all have the wrong and remote location. The correct location is Lucero. We had a beautiful experience! Everyone was so pleasant and welcoming. We had an amazing stay!"
United States
John
The price is CA $456
CA $502 total
includes taxes & fees
Mar 11 - Mar 12
Lucero - Luxury Treehouses

Cabin in Alto Boquete

Linda Vista Cabins
3.0 star property
9.2 out of 10, Wonderful, (17 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
Linda Vista Cabins

Condo resort in Alto Boquete

Aires frescos de Boquete
2.0 star property
9.0 out of 10, Wonderful, (4 reviews)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
The price is CA $70
CA $77 total
includes taxes & fees
Mar 11 - Mar 12
Aires frescos de Boquete

Apartment in David

Peace N' Green
3.0 star property
The price is CA $122
CA $134 total
includes taxes & fees
Mar 24 - Mar 25
Peace N' Green

Villa in Los Naranjos

Casa Mate by Villa Alejandro
3.5 star property
6.0 out of 10, (2 reviews)
The price is CA $116
CA $153 total
includes taxes & fees
Mar 11 - Mar 12
Casa Mate by Villa Alejandro
The price is CA $169
CA $327 total
includes taxes & fees
Apr 7 - Apr 8
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo

Villa in Boquete

Villa Alejandro
3.5 star property
8.6 out of 10, Excellent, (141 reviews)
"Great location, great room and very responsive hotel."
United States
Tara
The price is CA $74
CA $111 total
includes taxes & fees
Mar 22 - Mar 23
Villa Alejandro

Apartment in Boquete

Aparthotel Los Pinos
2.5 star property
8.6 out of 10, Excellent, (17 reviews)
"The place was spacious, clean and comfortable. Great location and easy parking."
United States
Rebecca
The price is CA $162
CA $178 total
includes taxes & fees
Mar 11 - Mar 12
Aparthotel Los Pinos

Apartment in Boquete

Casa Reina by Villa Alejandro
3.5 star property
8.6 out of 10, Excellent, (18 reviews)
"The property is outside of the town proper, so is quiet and it is possible to see wildlife. The room was extremely clean and comfortable, and the staff was welcoming and friendly. The view from the balcony was amazing!"
Canada
Catherine
The price is CA $118
CA $157 total
includes taxes & fees
Mar 8 - Mar 9
Casa Reina by Villa Alejandro

Aparthotel in El Tropezón

Downtown Suites
3.0 star property
9.0 out of 10, Wonderful, (102 reviews)
"Good location, nice rooms, great value."
United States
Robert
Downtown Suites

Apartment in Boquete

El Cielo by Villa Alejandro
3.5 star property
9.4 out of 10, Exceptional, (101 reviews)
"Everything was perfect! The room was comfortable and clean. The proximity to town was great!Communication with the hosts was excellent!"
United States
Lee
El Cielo by Villa Alejandro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Los Anastacios Hotel Reviews

Find out more about Los Anastacios

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Los Anastacios. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Los Anastacios?

Yes, we offer vacation rentals close to popular points of interest in Los Anastacios, or you can go with a more remote option if you're looking for relaxation.

What are some of the best vacation rentals in Los Anastacios?

Homely 3-bedroom house in gorgeous Alto Boquete neighborhood: Visitors like this Los Anastacios vacation home rental. It comes with laundry facilities so you can feel at home during your trip. Kitchen amenities like a stovetop and a microwave can make your vacation run smoothly.

What’s there to see and do in Los Anastacios?

While you're exploring the area, Miguel de Cervantes Saavedra Park and Municipal Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Boquete Library and Boquete Community Players Theater and Events Center.

What are vacation rentals like in Los Anastacios?

Vacation rentals are privately owned properties you can book for a few days or a quick weekend in Los Anastacios. Vacation rentals feature amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, vacation rentals can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family gatherings.