Title: Book the Best Little Rock Medical District LUXURY Hotels - Upscale Hotels in Little Rock Medical District, Little Rock | Expedia.ca [Vacation Rentals in Little Rock](https://expedia.ca/Little-Rock-Vacation-Rentals.d602841.Travel-Guide-VacationRentals)[Flights to Little Rock](https://expedia.ca/Cheap-Flights-To-Little-Rock.d602841.Travel-Guide-Flights)[Little Rock Medical District Car Rentals](https://expedia.ca/Car-Rentals-In-Little-Rock-Medical-District.d6173382.Car-Rental-Guide)[Little Rock Medical District Vacations](https://expedia.ca/Little-Rock-Medical-District.d6173382.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Little Rock Medical District, Little Rock ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Little Rock Medical District Luxury Hotels Tonight [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2025-10-31&endDate=2025-11-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2025-11-01&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Little Rock Medical District Luxury Hotels ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/9ff9826c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/a3cc4f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/71985011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking (One-Bedroom)](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/b13e5390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Little Rock/Medical Center Little Rock Medical District 6.0/10 (1000) "Great rates and staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $72 CA $82 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Little-Rock-Hotels-Days-Inn-By-Wyndham-Little-RockMedical-Center.h14863.Hotel-Information) ![Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/4e907ea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/0a9736c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/a73a4d08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/81371704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garden Inn and Suites Little Rock Downtown Little Rock 8.4/10 Very good (619) "Always stay here but started showing wear and tear" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jeff [](https://www.expedia.ca/Little-Rock-Hotels-Garden-Inn-And-Suites-Little-Rock.h7790382.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/22c10060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, individually furnished, desk](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/6ba302d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/ae8c2036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![25-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/6bd865f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Markham House Suites - Little Rock Medical Center Little Rock Medical District 7.4/10 Good (979) "Clean room at a very reasonable price at a good location too" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimy [](https://www.expedia.ca/Little-Rock-Hotels-Markham-House-Suites-Little-Rock-Medical-Center.h1931002.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15®ionId=6173382&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Little Rock Medical District Hotel Reviews ![Garden Inn and Suites Little Rock](//images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/4e907ea6_y.jpg) ### Garden Inn and Suites Little Rock 10/10 Excellent "The hotel is a little old but Room was good and staff was very nice. " [](https://expedia.ca/Little-Rock-Hotels-Garden-Inn-And-Suites-Little-Rock.h7790382.Hotel-Information) ![Comfort Inn & Suites Presidential - Downtown Little Rock](//images.trvl-media.com/lodging/1000000/970000/969900/969830/b3591dcd_y.jpg) ### Comfort Inn & Suites Presidential - Downtown Little Rock 10/10 Excellent "Everything was perfect. loved the extra clean room, decor, comfortable bed. " [](https://expedia.ca/Little-Rock-Hotels-Comfort-Inn-Suites-Presidential.h969830.Hotel-Information) ![Wyndham Riverfront Little Rock](//images.trvl-media.com/lodging/1000000/20000/11500/11418/3fee30c2_y.jpg) ### Wyndham Riverfront Little Rock 10/10 Excellent "The breakfast was superb, along with the atrium area. The room and restroom was well-appointed with everything provided for a comfortable stay. The bed was very comfortable. We love that the lady at check-in asked if we preferred the 1st or 2nd floor, and gave a great local dinner recommendation which was wonderful. " [](https://expedia.ca/Little-Rock-Hotels-Wyndham-Riverfront-Little-Rock.h11418.Hotel-Information) ![Little Rock Marriott](//images.trvl-media.com/lodging/1000000/10000/1600/1564/1c885840_y.jpg) ### Little Rock Marriott 10/10 Excellent "Very clean and staff are very nice " [](https://expedia.ca/Little-Rock-Hotels-Little-Rock-Marriott.h1564.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Little Rock - Bryant](//images.trvl-media.com/lodging/4000000/3030000/3025200/3025107/42cf3852_y.jpg) ### La Quinta Inn & Suites by Wyndham Little Rock - Bryant 10/10 Excellent "Staff was amazing. Safe, quiet hotel. Very clean." [](https://expedia.ca/Little-Rock-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Little-Rock-Bryant.h3025107.Hotel-Information) ![Holiday Inn Little Rock-Airport-Conference Center by IHG](//images.trvl-media.com/lodging/1000000/20000/16000/15984/23d1b71b_y.jpg) ### Holiday Inn Little Rock-Airport-Conference Center by IHG 10/10 Excellent "Yes" [](https://expedia.ca/Little-Rock-Hotels-Holiday-Inn-Little-Rock-Airport-Conference-Center.h15984.Hotel-Information) ![DoubleTree by Hilton Little Rock](//images.trvl-media.com/lodging/1000000/30000/28100/28024/1ac4b0ff_y.jpg) ### DoubleTree by Hilton Little Rock 10/10 Excellent "Yes" [](https://expedia.ca/Little-Rock-Hotels-DoubleTree-By-Hilton-Little-Rock.h28024.Hotel-Information) ![Days Inn by Wyndham Little Rock/Medical Center](//images.trvl-media.com/lodging/1000000/20000/14900/14863/9ff9826c_y.jpg) ### Days Inn by Wyndham Little Rock/Medical Center 10/10 Excellent "wasn’t impressed with breakfast " [](https://expedia.ca/Little-Rock-Hotels-Days-Inn-By-Wyndham-Little-RockMedical-Center.h14863.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury getaway to Little Rock Medical District? > Use Expedia to help you arrange a flight to Clinton National Airport Airport (LIT) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Little Rock Medical District offers. During your visit, you might want to enjoy the restaurants which Little Rock Medical District is known for. ### What's there to see and do in Little Rock Medical District? > Enjoy all that Little Rock Medical District has to offer and visit Little Rock Zoo, War Memorial Stadium, and Park Plaza Mall. If you have spare time during your trip, you might want to make a stop at Hillary Rodham Clinton Children's Library and Learning Center and Jack Stephens Center. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Farmstay in Arkansas](https://www.expedia.ca/Arkansas-Agritourism.d205-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Arkansas](https://www.expedia.ca/Arkansas-Apart-Hotels.d205-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Arkansas](https://www.expedia.ca/Arkansas-Apartments.d205-aaApartments.Travel-Guide-Accommodation) - [B&B in Arkansas](https://www.expedia.ca/Arkansas-Bed-And-Breakfast.d205-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Arkansas](https://www.expedia.ca/Arkansas-Cabins.d205-aaCabins.Travel-Guide-Accommodation) - [Castles in Arkansas](https://www.expedia.ca/Arkansas-Castles.d205-aaCastles.Travel-Guide-Accommodation) - [Chalets in Arkansas](https://www.expedia.ca/Arkansas-Chalets.d205-aaChalets.Travel-Guide-Accommodation) - 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