Title: Book the Best Little Rock Medical District LUXURY Hotels - Upscale Hotels in Little Rock Medical District, Little Rock | Expedia.ca [Vacation Rentals in Little Rock](https://expedia.ca/Little-Rock-Vacation-Rentals.d602841.Travel-Guide-VacationRentals)[Flights to Little Rock](https://expedia.ca/Cheap-Flights-To-Little-Rock.d602841.Travel-Guide-Flights)[Little Rock Medical District Car Rentals](https://expedia.ca/Car-Rentals-In-Little-Rock-Medical-District.d6173382.Car-Rental-Guide)[Little Rock Medical District Vacations](https://expedia.ca/Little-Rock-Medical-District.d6173382.Destination-Travel-Guides) ![ARKANSAS STATE CAPITOL BUILDING NIGHT CITY LIGHTS](https://images.trvl-media.com/place/6173382/58c70d58-f337-46d1-b07f-80ff17115e80.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Little Rock Medical District, Little Rock - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Little Rock Medical District Luxury Hotels Tonight [Jan 6 - Jan 7](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2026-01-06&endDate=2026-01-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Jan 7 - Jan 8](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2026-01-07&endDate=2026-01-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Little Rock Medical District luxury hotels ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/9ff9826c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/e8aa9e1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/71985011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/a3cc4f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Little Rock/Medical Center [](https://www.expedia.ca/Little-Rock-Hotels-Days-Inn-By-Wyndham-Little-RockMedical-Center.h14863.Hotel-Information) Little Rock Medical District 6.0/10 (1006) "Easy check in, Friendly personel. Best deal for the price near UAMS" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol CA $76 CA $87 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/Little-Rock-Hotels-Days-Inn-By-Wyndham-Little-RockMedical-Center.h14863.Hotel-Information) ![Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/4e907ea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/81371704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/079735d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/0a9736c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garden Inn and Suites Little Rock [](https://www.expedia.ca/Little-Rock-Hotels-Garden-Inn-And-Suites-Little-Rock.h7790382.Hotel-Information) Downtown Little Rock 8.4/10 Very good (628) "The hotel is a little old but Room was good and staff was very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael [](https://www.expedia.ca/Little-Rock-Hotels-Garden-Inn-And-Suites-Little-Rock.h7790382.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/22c10060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/ae8c2036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/f7355cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/6ba302d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Markham House Suites - Little Rock Medical Center [](https://www.expedia.ca/Little-Rock-Hotels-Markham-House-Suites-Little-Rock-Medical-Center.h1931002.Hotel-Information) Little Rock Medical District 7.4/10 Good (979) "This place was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronald [](https://www.expedia.ca/Little-Rock-Hotels-Markham-House-Suites-Little-Rock-Medical-Center.h1931002.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-20&endDate=2026-01-21®ionId=6173382&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Little Rock Medical District Hotel Reviews ![Wyndham Riverfront Little Rock](https://images.trvl-media.com/lodging/1000000/20000/11500/11418/3fee30c2_y.jpg) ### Wyndham Riverfront Little Rock 10/10 Excellent "Great restaurant and hospitality" [](https://expedia.ca/Little-Rock-Hotels-Wyndham-Riverfront-Little-Rock.h11418.Hotel-Information) ![Hilton Garden Inn North Little Rock](https://images.trvl-media.com/lodging/3000000/2840000/2838700/2838681/c5ee8632_y.jpg) ### Hilton Garden Inn North Little Rock 10/10 Excellent "Beautiful property " [](https://expedia.ca/Little-Rock-Hotels-Hilton-Garden-Inn-North-Little-Rock.h2838681.Hotel-Information) ![Comfort Inn & Suites Presidential - Downtown Little Rock](https://images.trvl-media.com/lodging/1000000/970000/969900/969830/b3591dcd_y.jpg) ### Comfort Inn & Suites Presidential - Downtown Little Rock 10/10 Excellent "Love it!!!" [](https://expedia.ca/Little-Rock-Hotels-Comfort-Inn-Suites-Presidential.h969830.Hotel-Information) ![Days Inn by Wyndham Little Rock/Medical Center](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/9ff9826c_y.jpg) ### Days Inn by Wyndham Little Rock/Medical Center 10/10 Excellent "Clean friendly and convenient " [](https://expedia.ca/Little-Rock-Hotels-Days-Inn-By-Wyndham-Little-RockMedical-Center.h14863.Hotel-Information) ![Little Rock Marriott](https://images.trvl-media.com/lodging/1000000/10000/1600/1564/1c885840_y.jpg) ### Little Rock Marriott 10/10 Excellent "I did not eat breakfast at the hotel." [](https://expedia.ca/Little-Rock-Hotels-Little-Rock-Marriott.h1564.Hotel-Information) ![DoubleTree by Hilton Little Rock](https://images.trvl-media.com/lodging/1000000/30000/28100/28024/1ac4b0ff_y.jpg) ### DoubleTree by Hilton Little Rock 10/10 Excellent "Staff and valet was very helpful and understanding about additional services and guest " [](https://expedia.ca/Little-Rock-Hotels-DoubleTree-By-Hilton-Little-Rock.h28024.Hotel-Information) ![Garden Inn and Suites Little Rock](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/4e907ea6_y.jpg) ### Garden Inn and Suites Little Rock 10/10 Excellent "Was actually quiet even tho right by the freeway. Getting a make over it seemed new bathrooms was really nice" [](https://expedia.ca/Little-Rock-Hotels-Garden-Inn-And-Suites-Little-Rock.h7790382.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury getaway to Little Rock Medical District? ### What's there to see and do in Little Rock Medical District? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Farmstay in Arkansas ](https://www.expedia.ca/Arkansas-Agritourism.d205-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Arkansas ](https://www.expedia.ca/Arkansas-Apart-Hotels.d205-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Arkansas ](https://www.expedia.ca/Arkansas-Apartments.d205-aaApartments.Travel-Guide-Accommodation) - [B&B in Arkansas ](https://www.expedia.ca/Arkansas-Bed-And-Breakfast.d205-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Arkansas ](https://www.expedia.ca/Arkansas-Cabins.d205-aaCabins.Travel-Guide-Accommodation) - 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