Title: Book the Best Little Rock Medical District LUXURY Hotels - Upscale Hotels in Little Rock Medical District, Little Rock | Expedia.ca [Vacation Rentals in Little Rock](https://expedia.ca/Little-Rock-Vacation-Rentals.d602841.Travel-Guide-VacationRentals)[Flights to Little Rock](https://expedia.ca/Cheap-Flights-To-Little-Rock.d602841.Travel-Guide-Flights)[Little Rock Medical District Car Rentals](https://expedia.ca/Car-Rentals-In-Little-Rock-Medical-District.d6173382.Car-Rental-Guide)[Little Rock Medical District Vacations](https://expedia.ca/Little-Rock-Medical-District.d6173382.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Little Rock Medical District, Little Rock ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Little Rock Medical District Luxury Hotels Tonight [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2025-09-29&endDate=2025-09-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2025-09-30&endDate=2025-10-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6173382&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Little Rock Medical District Luxury Hotels ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/9ff9826c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/71985011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/a3cc4f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking (One-Bedroom)](https://images.trvl-media.com/lodging/1000000/20000/14900/14863/b13e5390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Little Rock/Medical Center Little Rock Medical District 6.2/10 (1011) "Wonderful stay" CA $71 CA $82 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Little-Rock-Hotels-Days-Inn-By-Wyndham-Little-RockMedical-Center.h14863.Hotel-Information) ![Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/4e907ea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/a73a4d08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/81371704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/079735d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garden Inn and Suites Little Rock Downtown Little Rock 8.4/10 Very good (608) "No laundry soap at the front desk but other than that it’s a decent motel. " CA $115 CA $140 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Little-Rock-Hotels-Garden-Inn-And-Suites-Little-Rock.h7790382.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/22c10060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![25-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/6bd865f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/f7355cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1940000/1931100/1931002/ae8c2036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Markham House Suites - Little Rock Medical Center Little Rock Medical District 7.4/10 Good (979) "This place was great." [](https://www.expedia.ca/Little-Rock-Hotels-Markham-House-Suites-Little-Rock-Medical-Center.h1931002.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-13&endDate=2025-10-14®ionId=6173382&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Little Rock Medical District Hotel Reviews ![DoubleTree by Hilton Little Rock](//images.trvl-media.com/lodging/1000000/30000/28100/28024/1ac4b0ff_y.jpg) ### DoubleTree by Hilton Little Rock 10/10 Excellent "Yes workplace met my needs" [](https://expedia.ca/Little-Rock-Hotels-DoubleTree-By-Hilton-Little-Rock.h28024.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Little Rock - Bryant](//images.trvl-media.com/lodging/4000000/3030000/3025200/3025107/42cf3852_y.jpg) ### La Quinta Inn & Suites by Wyndham Little Rock - Bryant 10/10 Excellent "Staff was very efficient and the room was great. Bed was great. Everything here at this hotel i would recommend. " [](https://expedia.ca/Little-Rock-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Little-Rock-Bryant.h3025107.Hotel-Information) ![Comfort Inn & Suites Presidential - Downtown Little Rock](//images.trvl-media.com/lodging/1000000/970000/969900/969830/c58254bb_y.jpg) ### Comfort Inn & Suites Presidential - Downtown Little Rock 10/10 Excellent "Quick overnight stay was quiet and comfortable. " [](https://expedia.ca/Little-Rock-Hotels-Comfort-Inn-Suites-Presidential.h969830.Hotel-Information) ![Wyndham Riverfront Little Rock](//images.trvl-media.com/lodging/1000000/20000/11500/11418/3fee30c2_y.jpg) ### Wyndham Riverfront Little Rock 10/10 Excellent "It was really nice " [](https://expedia.ca/Little-Rock-Hotels-Wyndham-Riverfront-Little-Rock.h11418.Hotel-Information) ![Little Rock Marriott](//images.trvl-media.com/lodging/1000000/10000/1600/1564/1c885840_y.jpg) ### Little Rock Marriott 10/10 Excellent "." [](https://expedia.ca/Little-Rock-Hotels-Little-Rock-Marriott.h1564.Hotel-Information) ![Days Inn by Wyndham Little Rock/Medical Center](//images.trvl-media.com/lodging/1000000/20000/14900/14863/9ff9826c_y.jpg) ### Days Inn by Wyndham Little Rock/Medical Center 10/10 Excellent "Wonderful stay" [](https://expedia.ca/Little-Rock-Hotels-Days-Inn-By-Wyndham-Little-RockMedical-Center.h14863.Hotel-Information) ![Garden Inn and Suites Little Rock](//images.trvl-media.com/lodging/8000000/7800000/7790400/7790382/4e907ea6_y.jpg) ### Garden Inn and Suites Little Rock 10/10 Excellent "We always stay here when we are in Little Rock. It’s across the street from UAMS and is so convenient. The people are very nice and the rooms are clean. We call it our home away from home. " [](https://expedia.ca/Little-Rock-Hotels-Garden-Inn-And-Suites-Little-Rock.h7790382.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury getaway to Little Rock Medical District? > Use Expedia to help you arrange a flight to Clinton National Airport Airport (LIT) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Little Rock Medical District offers. During your visit, you might want to enjoy the restaurants which Little Rock Medical District is known for. ### What's there to see and do in Little Rock Medical District? > Enjoy all that Little Rock Medical District has to offer and visit Little Rock Zoo, War Memorial Stadium, and Park Plaza Mall. If you have spare time during your trip, you might want to make a stop at Jack Stephens Center and University of Arkansas at Little Rock Planetarium. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Farmstay in Arkansas](https://www.expedia.ca/Arkansas-Agritourism.d205-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Arkansas](https://www.expedia.ca/Arkansas-Apart-Hotels.d205-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Arkansas](https://www.expedia.ca/Arkansas-Apartments.d205-aaApartments.Travel-Guide-Accommodation) - [B&B in Arkansas](https://www.expedia.ca/Arkansas-Bed-And-Breakfast.d205-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Arkansas](https://www.expedia.ca/Arkansas-Cabins.d205-aaCabins.Travel-Guide-Accommodation) - [Castles in Arkansas](https://www.expedia.ca/Arkansas-Castles.d205-aaCastles.Travel-Guide-Accommodation) - [Chalets in Arkansas](https://www.expedia.ca/Arkansas-Chalets.d205-aaChalets.Travel-Guide-Accommodation) - 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