Title: Hotels by La Quinta Inn & Suites in Little Italy from CA $125 | Expedia.ca [Little Italy Travel Guide](https://expedia.ca/San-Diego-Little-Italy.dx6161280)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Little Italy Car Rentals](https://expedia.ca/Car-Rentals-In-Little-Italy.d6161280.Car-Rental-Guide)[Little Italy Vacations](https://expedia.ca/Little-Italy.d6161280.Destination-Travel-Guides) ![SanDiego_LittleItaly_6161280_002](https://images.trvl-media.com/place/6161280/098cc82a-fc3d-48ca-9dda-57fd8fa9ab05.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in Little Italy from CA $125 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=6161280&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 16 - Dec 17](https://www.expedia.ca/Hotel-Search?regionId=6161280&startDate=2025-12-16&endDate=2025-12-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6161280&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6161280&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Little Italy La Quinta Inn & Suites ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/b2f86861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/e912e2a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/fb3ae923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/3e11c449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Diego Mission Bay [](https://www.expedia.ca/San-Diego-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Diego-Mission-Bay.h11366.Hotel-Information) Pacific Beach 8.0/10 Very good (1432) "Friendly staff, clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice CA $124 CA $142 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/San-Diego-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Diego-Mission-Bay.h11366.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/49f2cd82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/4b32319c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/0d512cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/8ae9b43e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham San Diego - Miramar [](https://www.expedia.ca/San-Diego-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Miramar.h5684.Hotel-Information) Rancho Peñasquitos 7.8/10 Good (1096) "Very nice roomsGreat staff breakfast was decent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen CA $109 CA $125 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Miramar.h5684.Hotel-Information) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/079ae4ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/bfd1ccfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/be33bca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/4e7175aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham San Diego Chula Vista [](https://www.expedia.ca/Chula-Vista-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Chula-Vista.h22810.Hotel-Information) Chula Vista 8.6/10 Excellent (1497) "Everything was great, staff , Room , clean , great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis CA $137 CA $151 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Chula-Vista-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Chula-Vista.h22810.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-29&endDate=2025-12-30®ionId=6161280&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLittle-Italy-San-Diego-Hotels-La-Quinta-Inn-Suites.0-n6161280-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLittle-Italy-San-Diego-Hotels-La-Quinta-Inn-Suites.0-n6161280-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Little Italy Hotel Reviews ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Clean rooms, friendly staff" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Our suite was beautiful and spacious. We hosted our friends in it every day and there was so much space. The decor is so festive and fun. The staff was very helpful and the valet guys were helpful. We had a nice time. Feedback: The shower water was not hot, and the shower leaked water all over the floor every time someone showered. Full length mirrors or more mirrors would be nice for multiple people being able to get ready at once. There were randoms wandering the floors and all restaurants and bars were packed with outsiders. It would be nice to have security by the stairs. And limit the number of outsiders because the people who pay to stay were having to leave the premise to get food/drinks. " [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "We had a great stay! Everything was clean and the staff was phenomenal!! " [](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Nice hotel, very clean. " [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Hampton Inn & Suites by Hilton San Diego SeaWorld](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "Excellent " [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Legacy Resort Hotel & Spa](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4_y.jpg) ### Legacy Resort Hotel & Spa 10/10 Excellent "Very well and clean " [](https://expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Always love staying here. Staff was very courteous and the rooms very clean. " [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Room was spotless. Staff were really nice." [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "yes " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ## Find out more about Little Italy ## Little Italy Hotels Guide Expedia.ca offers a selection of 8412 hotels in Little Italy. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Little Italy. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Little Italy neighborhood you prefer. Go ahead. 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