Title: Book the Best BUSINESS Hotels in Lexington in 2026 | Expedia.ca [Hotels in Lexington](https://expedia.ca/Lexington-Hotels.d10084.Travel-Guide-Hotels)[Vacation Rentals in Lexington](https://expedia.ca/Lexington-Vacation-Rentals.d10084.Travel-Guide-VacationRentals)[Flights to Lexington](https://expedia.ca/Cheap-Flights-To-Lexington.d10084.Travel-Guide-Flights)[Things to do in Lexington](https://expedia.ca/Things-To-Do-In-Lexington.d10084.Travel-Guide-Activities)[Lexington Car Rentals](https://expedia.ca/Car-Rentals-In-Lexington.d10084.Car-Rental-Guide)[Lexington Vacation Packages](https://expedia.ca/Lexington.d10084.Destination-Travel-Guides) ![A beautiful Lake Murray sunset from Dreher Shoals Dam on the Saluda River. Lake Murray is about 12 miles northwest of Columbia, South Carolina. This picture was taken in August 2012 from the south side of the Dreher Shoals Dam. Lake Murray is located within 4 counties of central South Carolina. It's a popular lake for boating, fishing and water sports. My wife and I are fortunate to live on this beautiful lake - about 10 miles by boat from this spot. #lakemurray #lakemurraysc](https://images.trvl-media.com/place/10084/b4dc9de7-6d38-43a4-9bf6-320c4ac52431.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Mel Coker # Find Business Hotels in Lexington, SC from CA $107 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lexington Business Hotels Tonight [Dec 23 - Dec 24](https://www.expedia.ca/Hotel-Search?regionId=10084&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 24 - Dec 25](https://www.expedia.ca/Hotel-Search?regionId=10084&startDate=2025-12-24&endDate=2025-12-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=10084&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=10084&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Lexington Hotel Reviews ![La Quinta Inn by Wyndham Columbia SE / Fort Jackson](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e_y.jpg) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson 10/10 Excellent "The updated room is esthetically pleasing and modern. Best stay for your dollar in this area. The staff is all pleasant and even through the aging of the building they seem to be managing well. The elevators are a lil janky but they work. I didn't try the breakfast this visit. " [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![ La Quinta Inn by Wyndham Columbia NE/Fort Jackson](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50_y.jpg) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson 10/10 Excellent "Clean room" [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, SC](https://images.trvl-media.com/lodging/1000000/210000/202900/202867/04e820c9_y.jpg) ### Country Inn & Suites by Radisson, Columbia, SC 10/10 Excellent "The staff were amazing. Very helpful and welcoming. " [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h202867.Hotel-Information) ![Lexington Expo Hotel by IHG](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/e611a2e7_y.jpg) ### Lexington Expo Hotel by IHG 10/10 Excellent "Great location " [](https://expedia.ca/Lexington-Hotels-Lexington-Expo-Hotel-By-IHG.h1823665.Hotel-Information) ![Sleep Inn Columbia](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf_y.jpg) ### Sleep Inn Columbia 10/10 Excellent "Staff friendly and very helpful. Room clean and comfortable" [](https://expedia.ca/Columbia-Hotels-Sleep-Inn-At-Bush-River-Road.h126908.Hotel-Information) ![Hilton Garden Inn Columbia/Harbison](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "Yes" [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Courtyard by Marriott Columbia Downtown at USC](https://images.trvl-media.com/lodging/1000000/10000/2300/2289/w3996h2667x0y0-8dd1e3e0_y.jpg) ### Courtyard by Marriott Columbia Downtown at USC 10/10 Excellent "Friendly staff. Newly renovated. Clean . " [](https://expedia.ca/Columbia-Hotels-Courtyard-By-Marriott-Columbia-Downtown-At-USC.h2289.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "The staff were very friendly, the room was clean and comfortable and the breakfast was excellent. The location is close to everything we needed. We will stay again the next time we’re in the area. " [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "Room was not only beautiful but very clean. Staff was gracious - it was a perfect stay. " [](https://expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Lexington cost? ### What are the best business-friendly hotels in Lexington? ### How many business-friendly hotels are there in Lexington? ### What are the best cheap business-friendly hotels in Lexington? ### What are the top business-friendly motels in Lexington? ### Are there any family-friendly hotels in Lexington that are also business friendly? ### Why book your business-friendly hotel in Lexington with Expedia? ### How can I find cheap business-friendly hotels in Lexington? ### What is there to do in Lexington near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - More ways to book - [Hotels near Columbia Metropolitan ](https://www.expedia.ca/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - 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