Title: Hotels by Wyndham Extra Holidays in Lake Nona Medical City | Expedia.ca [Lake Nona Medical City Travel Guide](https://expedia.ca/Orlando-Lake-Nona-Medical-City.dx6197057)[Vacation Rentals in Orlando](https://expedia.ca/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals)[Flights to Orlando](https://expedia.ca/Cheap-Flights-To-Orlando.d178294.Travel-Guide-Flights)[Things to do in Orlando](https://expedia.ca/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities)[Lake Nona Medical City Car Rentals](https://expedia.ca/Car-Rentals-In-Lake-Nona-Medical-City.d6197057.Car-Rental-Guide)[Lake Nona Medical City Vacations](https://expedia.ca/Lake-Nona-Medical-City.d6197057.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Wyndham Extra Holidays in Lake Nona Medical City ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2025-10-06&endDate=2025-10-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Lake Nona Medical City Wyndham Extra Holidays Hotels ![4 outdoor pools, cabanas (surcharge), sun loungers](https://images.trvl-media.com/lodging/2000000/1550000/1547400/1547308/fc2da8d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/2000000/1550000/1547400/1547308/8c70d65b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1550000/1547400/1547308/d4007ea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-golf](https://images.trvl-media.com/lodging/2000000/1550000/1547400/1547308/79163ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Wyndham Bonnet Creek Orlando 9.2/10 Wonderful (1008) "Great option for those looking to make the most of their Disney vacation while still looking for rest and relaxation." [](https://www.expedia.ca/Orlando-Hotels-Club-Wyndham-Bonnet-Creek.h1547308.Hotel-Information) ![2 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/1000000/460000/456400/456398/d804678d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/456400/456398/112efcbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/456400/456398/11b825bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry](https://images.trvl-media.com/lodging/1000000/460000/456400/456398/c43e187f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Wyndham Cypress Palms Kissimmee 9.0/10 Wonderful (1816) "Nice place to stay" [](https://www.expedia.ca/Orlando-Hotels-Club-Wyndham-Cypress-Palms.h456398.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/12000000/11600000/11593400/11593315/7e95ac62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/12000000/11600000/11593400/11593315/a1c61f9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, blackout drapes, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/12000000/11600000/11593400/11593315/99b96020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![STD - Studio Deluxe Sleeps 2 | Private kitchen](https://images.trvl-media.com/lodging/12000000/11600000/11593400/11593315/f36bbda2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WorldMark Orlando - Kingstown Reef International Drive District 9.2/10 Wonderful (530) "Excellent hotel! Very clean property! Great location! The staff was nice! " [](https://www.expedia.ca/Orlando-Hotels-WorldMark-Orlando-Kingstown-Reef.h11593315.Hotel-Information) ![10 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/5000000/4190000/4188600/4188525/4fbd0446.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/5000000/4190000/4188600/4188525/5d2bdbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/5000000/4190000/4188600/4188525/adbc6d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 3 Bedrooms | Living room](https://images.trvl-media.com/lodging/5000000/4190000/4188600/4188525/6b156d24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WorldMark Reunion Reunion 9.4/10 Exceptional (580) "Loved it, will definitely be back! " [](https://www.expedia.ca/Orlando-Hotels-Club-Wyndham-Reunion.h4188525.Hotel-Information) ![Outdoor pool, open 8:00 AM to 11:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/60000/55800/55781/5da16da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/55800/55781/158664f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms | Living room](https://images.trvl-media.com/lodging/1000000/60000/55800/55781/2fe8c05f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/60000/55800/55781/a9dc94ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Wyndham Orlando International International Drive District 9.4/10 Exceptional (614) "We had a great experience " [](https://www.expedia.ca/Orlando-Hotels-Club-Wyndham-Orlando-International.h55781.Hotel-Information) ![2 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/16000000/15840000/15835700/15835606/e16e48fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Body treatments, aromatherapy, hot stone massages, body wraps](https://images.trvl-media.com/lodging/16000000/15840000/15835700/15835606/a7550847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Condo, 1 Bedroom](https://images.trvl-media.com/lodging/16000000/15840000/15835700/15835606/d7b74bef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/16000000/15840000/15835700/15835606/f348d872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Wyndham Star Island Kissimmee 8.2/10 Very good (438) "The rooms were very clean & equipped with every little item we were going to need in the kitchen/bedrooms/bedrooms. We also had washer/dryer to leave with clean clothes from our stay. I will definitely recommend this place for a family/friend getaway. " [](https://www.expedia.ca/Orlando-Hotels-Club-Wyndham-Star-Island.h15835606.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-19&endDate=2025-10-20®ionId=6197057&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLake-Nona-Medical-City-Orlando-Hotels-Wyndham-Extra-Holidays.0-n6197057-0--bWyndhamExtraHolidays.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLake-Nona-Medical-City-Orlando-Hotels-Wyndham-Extra-Holidays.0-n6197057-0--bWyndhamExtraHolidays.Travel-Guide-Filter-Hotels) ## Top Lake Nona Medical City Hotel Reviews ![Sheraton Vistana Villages Resort Villas, I-Drive/Orlando](//images.trvl-media.com/lodging/1000000/540000/539500/539487/88f9edce_y.jpg) ### Sheraton Vistana Villages Resort Villas, I-Drive/Orlando 10/10 Excellent "Outstanding, superb. Would love to stay there longer. The most comfortable bed I've ever slept in. Fantastic pool, great staff. Only issue was the dirty bath therefore didn't use. Thoroughly recommended. Lots of eating places nearby but you do need a car." [](https://expedia.ca/Orlando-Hotels-Sheraton-Vistana-Villages-Resort-Villas.h539487.Hotel-Information) ![DoubleTree by Hilton at the Entrance to Universal Orlando](//images.trvl-media.com/lodging/1000000/10000/5400/5398/4997b5df_y.jpg) ### DoubleTree by Hilton at the Entrance to Universal Orlando 10/10 Excellent "Front desk was friendly and helpful. " [](https://expedia.ca/Orlando-Hotels-DoubleTree-By-Hilton-At-The-Entrance-To-Universal-Orlando.h5398.Hotel-Information) ![Universal's Cabana Bay Beach Resort](//images.trvl-media.com/lodging/6000000/5970000/5963300/5963292/63940f45_y.jpg) ### Universal's Cabana Bay Beach Resort 10/10 Excellent "Alwaya great" [](https://expedia.ca/Orlando-Hotels-Universals-Cabana-Bay-Beach-Resort.h5963292.Hotel-Information) ![Wyndham I-Drive Avanti Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/4000/3916/55b45a9e_y.jpg) ### Wyndham I-Drive Avanti Resort & Conference Center 10/10 Excellent "This is my second time staying at this hotel and the cleaning services were on point everday the came to refresh the rooms! Excellent service!" [](https://expedia.ca/Orlando-Hotels-Avanti-Palms-Resort-And-Conference-Center.h3916.Hotel-Information) ![Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando](//images.trvl-media.com/lodging/1000000/30000/23200/23110/ade3b60d_y.jpg) ### Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando 10/10 Excellent "Great place " [](https://expedia.ca/Orlando-Hotels-Sheraton-Vistana-Resort-Villas.h23110.Hotel-Information) ![Marriott's Grande Vista](//images.trvl-media.com/lodging/1000000/860000/853600/853519/77708f65_y.jpg) ### Marriott's Grande Vista 10/10 Excellent "Quiet " [](https://expedia.ca/Orlando-Hotels-Marriotts-Grande-Vista.h853519.Hotel-Information) ![Universal's Endless Summer Resort - Dockside Inn and Suites](//images.trvl-media.com/lodging/34000000/33780000/33770400/33770341/c8859517_y.jpg) ### Universal's Endless Summer Resort - Dockside Inn and Suites 10/10 Excellent "." [](https://expedia.ca/Orlando-Hotels-Universals-Endless-Summer-Dockside-Inn-Suites.h33770341.Hotel-Information) ![Westgate Lakes Resort & Spa Universal Studios Area](//images.trvl-media.com/lodging/1000000/810000/805000/804984/86e77c07_y.jpg) ### Westgate Lakes Resort & Spa Universal Studios Area 10/10 Excellent "Every thing and everyone were great! Definitely will be coming back to stay here! Room was clean and neat❤️" [](https://expedia.ca/Orlando-Hotels-Westgate-Lakes-Resort-Spa-Universal-Studios-Area.h804984.Hotel-Information) ![Holiday Inn Resort Orlando - Lake Buena Vista by IHG](//images.trvl-media.com/lodging/1000000/20000/19600/19535/aa564e7f_y.jpg) ### Holiday Inn Resort Orlando - Lake Buena Vista by IHG 10/10 Excellent "Clean room and easy to navigate. " [](https://expedia.ca/Orlando-Hotels-Holiday-Inn-Resort-Orlando-Lake-Buena-Vista.h19535.Hotel-Information) ## Find out more about Lake Nona Medical City ## Lake Nona Medical City Hotels Guide Expedia.ca offers a selection of 27674 hotels in Lake Nona Medical City. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Lake Nona Medical City. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Lake Nona Medical City neighborhood you prefer. Go ahead. 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[Hotels with smoking rooms in Lake Nona](https://www.expedia.ca/Lake-Nona-Orlando-Hotels-Hotels-With-Smoking-Rooms.0-n6209488-0-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Lake Nona](https://www.expedia.ca/Lake-Nona-Orlando-Hotels-LGBT-Friendly-Hotel.0-n6209488-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Lake Hotels in Lake Nona](https://www.expedia.ca/Lake-Nona-Orlando-Hotels-Lake-Hotels.0-n6209488-0-tLakeHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Lake Nona](https://www.expedia.ca/Lake-Nona-Orlando-Hotels-Luxury-Hotel.0-n6209488-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Lake Nona](https://www.expedia.ca/Lake-Nona-Orlando-Hotels-Mountain-Hotels.0-n6209488-0-tMountainHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Lake Nona](https://www.expedia.ca/Lake-Nona-Orlando-Hotels-Oceanfront-Hotels.0-n6209488-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Lake Nona](https://www.expedia.ca/Lake-Nona-Orlando-Hotels-Pet-Friendly-Hotel.0-n6209488-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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[Flights to Orlando](https://www.expedia.ca/Cheap-Flights-To-Orlando.d178294.Travel-Guide-Flights) - [Flights from Orlando Intl.](https://www.expedia.ca/lp/airports/mco/flights-from-orlando-intl-airport) - [Flights from Bangor (BGR) to Orlando (MCO)](https://www.expedia.ca/lp/flights/bgr/mco/bangor-to-orlando) - [Flights from Buffalo (BUF) to Orlando (MCO)](https://www.expedia.ca/lp/flights/buf/mco/buffalo-to-orlando) - [Flights from Detroit (DTW) to Orlando (MCO)](https://www.expedia.ca/lp/flights/dtw/mco/detroit-to-orlando) - [Flights from Miami (MIA) to Orlando (MCO)](https://www.expedia.ca/lp/flights/mia/mco/miami-to-orlando) - [Flights from Syracuse (SYR) to Orlando (MCO)](https://www.expedia.ca/lp/flights/syr/mco/syracuse-to-orlando) - [Flights from Edmonton (YEG) to Orlando (MCO)](https://www.expedia.ca/lp/flights/yeg/mco/edmonton-to-orlando) - [Flights from Hamilton (YHM) to Orlando (MCO)](https://www.expedia.ca/lp/flights/yhm/mco/hamilton-to-orlando) - [Flights from Halifax (YHZ) to Orlando (MCO)](https://www.expedia.ca/lp/flights/yhz/mco/halifax-to-orlando) - 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[Flights from Toronto (YYZ) to Orlando (MCO)](https://www.expedia.ca/lp/flights/yyz/mco/toronto-to-orlando) - [Austin-Tindall Regional Park](https://www.expedia.ca/Austin-Tindall-Regional-Park-Orlando.d553248635961253122.Vacation-Attraction) - [Nemours Children's Hospital](https://www.expedia.ca/Nemours-Childrens-Hospital-Lake-Nona.d6154167.Vacation-Attraction) - [Visit Lake Hart](https://www.expedia.ca/Orlando-Lake-Hart.dx6360982) - [Visit Lake Nona](https://www.expedia.ca/Orlando-Lake-Nona.dx6209488) - [Walt Disney World® Resort](https://www.expedia.ca/Walt-Disney-World-Resort-Orlando.d6034120.Vacation-Attraction) - [Car rentals near Lake Nona](https://www.expedia.ca/Car-Rentals-In-Lake-Nona.d6209488.Car-Rental-Guide) - [Rental cars Orlando Intl. airport](https://www.expedia.ca/Car-Rentals-In-Orlando-Intl.d5194573.Car-Rental-Guide) - [Car rentals near Orlando](https://www.expedia.ca/Car-Rentals-In-Orlando.d178294.Car-Rental-Guide) - [Enterprise Rental Cars in Lake Nona](https://www.expedia.ca/Enterprise-Car-Rentals-In-Lake-Nona.d6209488-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Lake Nona](https://www.expedia.ca/Hertz-Car-Rentals-In-Lake-Nona.d6209488-c40.Car-Rental-Guide-Suppliers) - [United Rental Cars in Southeast Orlando](https://www.expedia.ca/United-Car-Rentals-In-Southeast-Orlando.d553248635976478881-c1088.Car-Rental-Guide-Suppliers) - [Zezgo Rental Cars in Southeast Orlando](https://www.expedia.ca/ZezGo-Car-Rentals-In-Southeast-Orlando.d553248635976478881-c1122.Car-Rental-Guide-Suppliers) - [Book Hotels in Lake Nona Medical City on Expedia.com](https://www.expedia.com/Lake-Nona-Medical-City-Orlando-Hotels-Wyndham-Extra-Holidays.0-n6197057-0--bWyndhamExtraHolidays.Travel-Guide-Filter-Hotels)