Title: Hotels by La Quinta Inn & Suites in Lake Nona Medical City from CA $101 | Expedia.ca [Lake Nona Medical City Travel Guide](https://expedia.ca/Orlando-Lake-Nona-Medical-City.dx6197057)[Vacation Rentals in Orlando](https://expedia.ca/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals)[Flights to Orlando](https://expedia.ca/Cheap-Flights-To-Orlando.d178294.Travel-Guide-Flights)[Things to do in Orlando](https://expedia.ca/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities)[Lake Nona Medical City Car Rentals](https://expedia.ca/Car-Rentals-In-Lake-Nona-Medical-City.d6197057.Car-Rental-Guide)[Lake Nona Medical City Vacations](https://expedia.ca/Lake-Nona-Medical-City.d6197057.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in Lake Nona Medical City from CA $101 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 1 - Jan 2](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2026-01-01&endDate=2026-01-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 2 - Jan 3](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2026-01-02&endDate=2026-01-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Lake Nona Medical City La Quinta Inn & Suites ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/4fbafd8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing Impaired Accessible)](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/9592f962.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/04e76f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/80f72df0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Orlando Airport North [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Airport-North.h120304.Hotel-Information) Airport North 7.4/10 Good (945) "Staff was very friendly, quick and easy check in. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $131 CA $147 total includes taxes & fees Jan 4 - Jan 5 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Airport-North.h120304.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/60000/50800/50718/9ca7ef63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50800/50718/19d92b9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50800/50718/6e978bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/60000/50800/50718/55babc1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Orlando South [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-South.h50718.Hotel-Information) Orlando 6.6/10 (1770) "The front desk was very friendly and helpful on accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Claudia CA $94 CA $106 total includes taxes & fees Jan 4 - Jan 5 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-South.h50718.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/40000000/39670000/39665300/39665265/97d95146.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/40000000/39670000/39665300/39665265/8d89f0a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/40000000/39670000/39665300/39665265/de647cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/40000000/39670000/39665300/39665265/efc9af30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Orlando - IDrive Theme Parks [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Drive-Theme-Parks.h39665265.Hotel-Information) International Drive District 8.6/10 Excellent (2422) "Clean room, helpful and friendly staff, great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jocelyn CA $135 CA $151 total includes taxes & fees Jan 4 - Jan 5 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Drive-Theme-Parks.h39665265.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/202500/202417/4d403af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/210000/202500/202417/d69fe5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/210000/202500/202417/a9ddda8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/210000/202500/202417/ca90f519.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Orlando UCF [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-UCF.h202417.Hotel-Information) Orlando 8.6/10 Excellent (2689) "Friendly staff and super clean rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $134 CA $151 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-UCF.h202417.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/202700/202659/w3837h2572x3y3-d9548385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/202700/202659/w3837h2572x3y3-aaf0d915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/202700/202659/w3837h2572x3y3-2870d6af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/210000/202700/202659/27828200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Orlando I Drive/Conv Ctr [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-I-DriveConv-Ctr.h202659.Hotel-Information) International Drive District 8.0/10 Very good (2223) "Awesome stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eddie CA $110 CA $124 total includes taxes & fees Jan 4 - Jan 5 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-I-DriveConv-Ctr.h202659.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/27300/27213/0c360557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27300/27213/0a09e445.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27300/27213/762c6ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/27300/27213/038a1a14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Orlando Airport West [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-By-Wyndham-Orlando-Airport-West.h27213.Hotel-Information) Orlando 6.0/10 (2604) "Location to airport and Disneyworld was great for the price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katrina CA $90 CA $101 total includes taxes & fees Jan 6 - Jan 7 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-By-Wyndham-Orlando-Airport-West.h27213.Hotel-Information) ![2 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/1000000/440000/439500/439491/60c4ab53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/440000/439500/439491/f35299a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/440000/439500/439491/9405a04f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/439500/439491/ab173d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Orlando Universal area [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Universal-Area.h439491.Hotel-Information) Florida Center 8.2/10 Very good (2234) "Breakfast was as expected and we liked that the hotel is pet friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Haydee CA $127 CA $143 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Universal-Area.h439491.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16800/16797/1530d308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Non Smoking (Executive)](https://images.trvl-media.com/lodging/1000000/20000/16800/16797/7dc5b9d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16800/16797/df2b4bbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/16800/16797/7f6cc94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Orlando International Drive North [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-By-Wyndham-Orlando-International-Drive-North.h16797.Hotel-Information) International Drive District 7.6/10 Good (1002) "Friendly staff, room was clean. Close to Universal Orlando and shopping centers" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gilfredo CA $122 CA $138 total includes taxes & fees Jan 4 - Jan 5 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-By-Wyndham-Orlando-International-Drive-North.h16797.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-15&endDate=2026-01-16®ionId=6197057&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLake-Nona-Medical-City-Orlando-Hotels-La-Quinta-Inn-Suites.0-n6197057-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLake-Nona-Medical-City-Orlando-Hotels-La-Quinta-Inn-Suites.0-n6197057-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Lake Nona Medical City Hotel Reviews ![Kompose Boutique Resort at Theme Parks](https://images.trvl-media.com/lodging/101000000/100840000/100837800/100837786/3cf09a4a_y.jpg) ### Kompose Boutique Resort at Theme Parks 10/10 Excellent "Excellent service, exceptionally clean suite." [](https://expedia.ca/Orlando-Hotels-Kompose-Boutique-Resort-At-Theme-Parks.h100837786.Hotel-Information) ![Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/ade3b60d_y.jpg) ### Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando 10/10 Excellent "The staff was great! The villa was perfect! I would definetly stay again. This is the perfect place to call home away from home. Having a full kitchen allowed us to save money on food. I love that there was a washer and dryer in the unit. And the kids were happy to have their own beds." [](https://expedia.ca/Orlando-Hotels-Sheraton-Vistana-Resort-Villas.h23110.Hotel-Information) ![Universal's Cabana Bay Beach Resort](https://images.trvl-media.com/lodging/6000000/5970000/5963300/5963292/63940f45_y.jpg) ### Universal's Cabana Bay Beach Resort 10/10 Excellent "Everything was great" [](https://expedia.ca/Orlando-Hotels-Universals-Cabana-Bay-Beach-Resort.h5963292.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Orlando Airport North](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/4fbafd8c_y.jpg) ### La Quinta Inn & Suites by Wyndham Orlando Airport North 10/10 Excellent "Very convenient location " [](https://expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Airport-North.h120304.Hotel-Information) ![Wyndham I-Drive Avanti Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/4000/3916/55b45a9e_y.jpg) ### Wyndham I-Drive Avanti Resort & Conference Center 10/10 Excellent "Great " [](https://expedia.ca/Orlando-Hotels-Avanti-Palms-Resort-And-Conference-Center.h3916.Hotel-Information) ![Hyatt Regency Orlando](https://images.trvl-media.com/lodging/1000000/10000/9600/9574/1bb0a2ac_y.jpg) ### Hyatt Regency Orlando 10/10 Excellent "The pool is fantastic and family friendly. Location is outstanding." [](https://expedia.ca/Orlando-Hotels-Hyatt-Regency-Orlando.h9574.Hotel-Information) ![DoubleTree by Hilton Hotel Orlando at SeaWorld](https://images.trvl-media.com/lodging/1000000/20000/18900/18874/69019073_y.jpg) ### DoubleTree by Hilton Hotel Orlando at SeaWorld 10/10 Excellent "Good Hoye" [](https://expedia.ca/Orlando-Hotels-DoubleTree-By-Hilton-Hotel-Orlando-At-SeaWorld.h18874.Hotel-Information) ![CoCo Key Hotel and Water Resort ](https://images.trvl-media.com/lodging/1000000/10000/300/228/73a42af2_y.jpg) ### CoCo Key Hotel and Water Resort 10/10 Excellent "It is a great place for families. I enjoyed having a room overlooking the waterpark. Staff was friendly. " [](https://expedia.ca/Orlando-Hotels-CoCo-Key-Hotel-And-Water-Resort-Orlando.h228.Hotel-Information) ![Caribe Royale Orlando](https://images.trvl-media.com/lodging/1000000/50000/40900/40865/033f2fa5_y.jpg) ### Caribe Royale Orlando 10/10 Excellent "The hotel was beautiful. Nice and clean staff was super and the bed felt amazing. " [](https://expedia.ca/Orlando-Hotels-Caribe-Royale-Orlando.h40865.Hotel-Information) ## Find out more about Lake Nona Medical City ## Lake Nona Medical City Hotels Guide Expedia.ca offers a selection of 27584 hotels in Lake Nona Medical City. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Lake Nona Medical City. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Lake Nona Medical City neighborhood you prefer. Go ahead. 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