Title: Book the Best ADVENTURE Hotels in Lake Nona Medical City in 2026 | Expedia.ca [Vacation Rentals in Orlando](https://expedia.ca/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals)[Flights to Orlando](https://expedia.ca/Cheap-Flights-To-Orlando.d178294.Travel-Guide-Flights)[Things to do in Orlando](https://expedia.ca/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities)[Lake Nona Medical City Car Rentals](https://expedia.ca/Car-Rentals-In-Lake-Nona-Medical-City.d6197057.Car-Rental-Guide)[Lake Nona Medical City Vacations](https://expedia.ca/Lake-Nona-Medical-City.d6197057.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lake Nona Medical City Hotels & Resorts for Couples Tonight [Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2026-02-04&endDate=2026-02-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6197057&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Lake Nona Medical City adventure hotels ![3 outdoor pools](https://images.trvl-media.com/lodging/5000000/4520000/4517700/4517659/9695c9aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/5000000/4520000/4517700/4517659/6539ddf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/5000000/4520000/4517700/4517659/3b8db3c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/5000000/4520000/4517700/4517659/8bc94256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Disney's Art Of Animation Resort [](https://www.expedia.ca/Orlando-Hotels-Disneys-Art-Of-Animation-Resort.h4517659.Hotel-Information) Bay Lake 8.8/10 Excellent (1,003 reviews) "Room was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jennifer [](https://www.expedia.ca/Orlando-Hotels-Disneys-Art-Of-Animation-Resort.h4517659.Hotel-Information) ![6 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/91c45539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/b1f61811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/de6f64bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/90000976.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando [](https://www.expedia.ca/Orlando-Hotels-Sheraton-Vistana-Resort-Villas.h23110.Hotel-Information) Orlando 9.2/10 Wonderful (4,501 reviews) "Room was very nice, staff helpful and great location for travelers. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $179 CA $201 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Orlando-Hotels-Sheraton-Vistana-Resort-Villas.h23110.Hotel-Information) ![Outdoor wedding area](https://images.trvl-media.com/lodging/2000000/1760000/1759600/1759572/w3541h1754x2y0-2f9e02a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/2000000/1760000/1759600/1759572/d2867ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/2000000/1760000/1759600/1759572/564d65cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1760000/1759600/1759572/2772ccec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Meliá Orlando Celebration [](https://www.expedia.ca/Orlando-Hotels-Melia-Orlando-Celebration.h1759572.Hotel-Information) Celebration 8.6/10 Excellent (1,568 reviews) "Great location for Disney parks." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carolyn CA $127 CA $194 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Orlando-Hotels-Melia-Orlando-Celebration.h1759572.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/480000/470900/470892/w4000h2663x0y0-13fc5e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/480000/470900/470892/w4000h2662x0y0-978e0b24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/480000/470900/470892/75a2af1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470900/470892/d5a0e2c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Lake Buena Vista in Marriott Village [](https://www.expedia.ca/Orlando-Hotels-Fairfield-Inn-Suites-Lake-Buena-Vista-In-Marriott-Village.h470892.Hotel-Information) Orlando 8.4/10 Very good (1,253 reviews) "Friendly staff, clean atmosphere. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristy CA $115 CA $137 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Orlando-Hotels-Fairfield-Inn-Suites-Lake-Buena-Vista-In-Marriott-Village.h470892.Hotel-Information) ![Water park](https://images.trvl-media.com/lodging/1000000/10000/3900/3858/18b2638a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/3900/3858/b9f1753f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3900/3858/43a6edaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water park](https://images.trvl-media.com/lodging/1000000/10000/3900/3858/e6f13136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Hotel & Water Park [](https://www.expedia.ca/Orlando-Hotels-Flamingo-Waterpark-Resort.h3858.Hotel-Information) Kissimmee 7.0/10 Good (1,814 reviews) "Great place to stayed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neuris CA $55 CA $107 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Orlando-Hotels-Flamingo-Waterpark-Resort.h3858.Hotel-Information) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/9600/9574/3363c0c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9600/9574/w3837h2557x3y4-650ed992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/9600/9574/d087c6a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9600/9574/b18a06a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Orlando [](https://www.expedia.ca/Orlando-Hotels-Hyatt-Regency-Orlando.h9574.Hotel-Information) International Drive District 9.2/10 Wonderful (1,961 reviews) "Very clean, friendly staff. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Madeline CA $266 CA $375 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/Orlando-Hotels-Hyatt-Regency-Orlando.h9574.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/24000000/23420000/23412300/23412221/ad59e7f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/24000000/23420000/23412300/23412221/81e6aa91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/24000000/23420000/23412300/23412221/461369d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/24000000/23420000/23412300/23412221/d0a13c82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orlando Theme Parks/Lake Buena Vista [](https://www.expedia.ca/Orlando-Hotels-SpringHill-Suites-By-Marriott-Orlando-Theme-ParksLake-Buena-Vista.h23412221.Hotel-Information) Orlando 8.6/10 Excellent (3,560 reviews) "Loved the pool area, very clean, good location, breakfast is decent, staff is great! " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jordana CA $157 CA $177 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Orlando-Hotels-SpringHill-Suites-By-Marriott-Orlando-Theme-ParksLake-Buena-Vista.h23412221.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/151100/151078/6d8cf201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/160000/151100/151078/9b9666d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/160000/151100/151078/11142937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/151100/151078/8eb6ba6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham Convention Ctr Closest Universal Orlando [](https://www.expedia.ca/Orlando-Hotels-Wingate-By-Wyndham-Convention-Ctr-Closest-Universal-Orlando.h151078.Hotel-Information) Florida Center 8.8/10 Excellent (1,527 reviews) "The room was very clean and the customer service was excellent! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reginald CA $128 CA $143 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Orlando-Hotels-Wingate-By-Wyndham-Convention-Ctr-Closest-Universal-Orlando.h151078.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/40000000/39670000/39665300/39665265/97d95146.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/40000000/39670000/39665300/39665265/de647cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/40000000/39670000/39665300/39665265/357d03c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/40000000/39670000/39665300/39665265/044ca03d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Orlando - IDrive Theme Parks [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Drive-Theme-Parks.h39665265.Hotel-Information) International Drive District 8.6/10 Excellent (2,491 reviews) "Everything was great, clean and breakfast included and pet friendly. Will definitely stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rosalba CA $128 CA $144 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Drive-Theme-Parks.h39665265.Hotel-Information) ![Room, 1 Queen Bed, Balcony | Balcony view](https://images.trvl-media.com/lodging/1000000/430000/425100/425071/39e0079b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/430000/425100/425071/c28b9420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/430000/425100/425071/adb5b195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/430000/425100/425071/d60a50f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Eo Inn - Downtown [](https://www.expedia.ca/Orlando-Hotels-The-Eo-Inn-Downtown.h425071.Hotel-Information) South Eola 8.0/10 Very good (1,002 reviews) "Very friendly staff and in a good location" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Daniel CA $135 CA $152 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Orlando-Hotels-The-Eo-Inn-Downtown.h425071.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-18&endDate=2026-02-19®ionId=6197057&adults=2&nearby_group=recreation&sort=RECOMMENDED&openPlayBack=true) ## Top Lake Nona Medical City Hotel Reviews ![Avanti International Resort](https://images.trvl-media.com/lodging/1000000/10000/3900/3832/b0f81967_y.jpg) ### Avanti International Resort 10/10 Excellent "Very good value. Great location. " [](https://expedia.ca/Orlando-Hotels-Avanti-International-Resort.h3832.Hotel-Information) ![Universal's Cabana Bay Beach Resort](https://images.trvl-media.com/lodging/6000000/5970000/5963300/5963292/63940f45_y.jpg) ### Universal's Cabana Bay Beach Resort 10/10 Excellent "Clear. Customer service. Transportation convenience " [](https://expedia.ca/Orlando-Hotels-Universals-Cabana-Bay-Beach-Resort.h5963292.Hotel-Information) ![Rosen Inn at Pointe Orlando](https://images.trvl-media.com/lodging/1000000/10000/8900/8892/8068a653_y.jpg) ### Rosen Inn at Pointe Orlando 10/10 Excellent "The room was spotless" [](https://expedia.ca/Orlando-Hotels-Rosen-Inn-At-Pointe-Orlando.h8892.Hotel-Information) ![DoubleTree by Hilton Hotel Orlando at SeaWorld](https://images.trvl-media.com/lodging/1000000/20000/18900/18874/69019073_y.jpg) ### DoubleTree by Hilton Hotel Orlando at SeaWorld 10/10 Excellent "Great cookies handed out during check in " [](https://expedia.ca/Orlando-Hotels-DoubleTree-By-Hilton-Hotel-Orlando-At-SeaWorld.h18874.Hotel-Information) ![Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/ade3b60d_y.jpg) ### Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando 10/10 Excellent "The condo was clean. The staff was friendly. The beds were comfortable and the coffee bar was great. Thank you so much." [](https://expedia.ca/Orlando-Hotels-Sheraton-Vistana-Resort-Villas.h23110.Hotel-Information) ![Marriott's Grande Vista](https://images.trvl-media.com/lodging/1000000/860000/853600/853519/77708f65_y.jpg) ### Marriott's Grande Vista 10/10 Excellent "Very quick and early check in, allowed late check out, clean rooms, gorgeous landscape " [](https://expedia.ca/Orlando-Hotels-Marriotts-Grande-Vista.h853519.Hotel-Information) ![Vacation Village Orlando, Celebration](https://images.trvl-media.com/lodging/2000000/1070000/1069000/1068973/fb6985f5_y.jpg) ### Vacation Village Orlando, Celebration 10/10 Excellent "First time staying there. Loved everything about the property " [](https://expedia.ca/Orlando-Hotels-Vacation-Village-At-Parkway.h1068973.Hotel-Information) ![Hyatt Regency Orlando International Airport](https://images.trvl-media.com/lodging/1000000/10000/2800/2754/acaa1e8b_y.jpg) ### Hyatt Regency Orlando International Airport 10/10 Excellent "The room was wonderful, and the view was nice. I’d give it 4.75 stars—only because of noise. It’s not the hotel’s fault. They have quiet signs posted. I could hear the people next door and people walking down the hall on and off all night. That’s not really fixable, but it did wake me a few times. I was just surrounded by really loud people. The staff were helpful and friendly. Really amazing. The food was very good. The ease of being able to walk right into the airport was wonderful. " [](https://expedia.ca/Orlando-Hotels-Hyatt-Regency-Orlando-International-Airport.h2754.Hotel-Information) ![DoubleTree by Hilton at the Entrance to Universal Orlando](https://images.trvl-media.com/lodging/1000000/10000/5400/5398/4997b5df_y.jpg) ### DoubleTree by Hilton at the Entrance to Universal Orlando 10/10 Excellent "Very nice " [](https://expedia.ca/Orlando-Hotels-DoubleTree-By-Hilton-At-The-Entrance-To-Universal-Orlando.h5398.Hotel-Information) ## Frequently asked questions ### Why book your hotel for couples in Lake Nona Medical City with Expedia? ### How can I find cheap hotels for couples in Lake Nona Medical City? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Adults Only Resorts & in Central Florida ](https://www.expedia.ca/Central-Florida-Hotels-Adults-Only-Resorts.0-0-d6048177-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Central Florida ](https://www.expedia.ca/Central-Florida-Hotels-Beach-Hotel.0-0-d6048177-tBeachHotel.Travel-Guide-Filter-Hotels) - 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