Title: Book the Best Lake City LUXURY Hotels - Upscale Hotels in Lake City, SC | Expedia.ca [Hotels in Lake City](https://expedia.ca/Lake-City-Hotels.d8506.Travel-Guide-Hotels)[Vacation Rentals in Lake City](https://expedia.ca/Lake-City-Vacation-Rentals.d8506.Travel-Guide-VacationRentals)[Lake City Car Rentals](https://expedia.ca/Car-Rentals-In-Lake-City.d8506.Car-Rental-Guide)[Lake City Vacation Packages](https://expedia.ca/Lake-City.d8506.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Lake City, SC ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lake City Luxury Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=8506&startDate=2025-10-15&endDate=2025-10-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=8506&startDate=2025-10-16&endDate=2025-10-17&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=8506&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=8506&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Lake City Luxury Hotels ## Top Lake City Hotel Reviews ![Quality Inn & Suites Florence Civic Center](//images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent "Bueno" [](https://expedia.ca/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Days Inn by Wyndham Florence Near Civic Center](//images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0_y.jpg) ### Days Inn by Wyndham Florence Near Civic Center 10/10 Excellent "Great" [](https://expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury trip to Lake City? > Use Expedia to arrange your flight to Florence, SC (FLO-Florence Regional) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Lake City has to offer. During your visit, you might want to enjoy the restaurants which Lake City is known for. ### When can I expect good weather in Lake City? > Planning for the weather is an important factor for making your trip to Lake City a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Lake City is 53 inches. ### What's there to see and do in Lake City? > Experience Lake City with a stop at Lions Park, The Bean Market, and Moore Farms Botanical Garden. If you have a bit of extra time while you're in the area, you might want to check out Lynches Lake Historical Society and Ronald E. McNair Life History Center. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Business Hotels in Charleston](https://www.expedia.ca/Charleston-Hotels-Business-Hotel.0-0-d179997-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in Charleston](https://www.expedia.ca/Charleston-Hotels-Green-Sustainable.0-0-d179997-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Charleston](https://www.expedia.ca/Charleston-Hotels-Hotel-With-Early-Check-In.0-0-d179997-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in Charleston](https://www.expedia.ca/Charleston-Hotels-Hotels-With-A-Lazy-River.0-0-d179997-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - [Coward Hotels](https://www.expedia.ca/Coward-Hotels.d3000353109.Travel-Guide-Hotels) - [Cheap Hotels in Florence County](https://www.expedia.ca/Destinations-In-Florence-County-Cheap-Hotels.0-0-d553248635976432658-tCheapHotels.Hotel-Filter-Destinations) - 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