Title: Book the Best BUSINESS Hotels in Lake City in 2025 | Expedia.ca [Hotels in Lake City](https://expedia.ca/Lake-City-Hotels.d8506.Travel-Guide-Hotels)[Vacation Rentals in Lake City](https://expedia.ca/Lake-City-Vacation-Rentals.d8506.Travel-Guide-VacationRentals)[Lake City Car Rentals](https://expedia.ca/Car-Rentals-In-Lake-City.d8506.Car-Rental-Guide)[Lake City Vacation Packages](https://expedia.ca/Lake-City.d8506.Destination-Travel-Guides) ![a stunning aerial panoramic shot of the blue waters of Lake Hartwell surrounded by vast miles of lush green trees and grass with powerful clouds at sunset in Fair Play South Carolina USA](https://images.trvl-media.com/place/8506/47c9f422-933e-4135-8743-774b754f1db4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Lake City, SC from CA $96 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lake City Business Hotels Tonight [Nov 9 - Nov 10](https://www.expedia.ca/Hotel-Search?regionId=8506&startDate=2025-11-09&endDate=2025-11-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Nov 10 - Nov 11](https://www.expedia.ca/Hotel-Search?regionId=8506&startDate=2025-11-10&endDate=2025-11-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=8506&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=8506&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Lake City Business Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84500/84460/82cbb71a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84500/84460/8fa66165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/90000/84500/84460/22714bab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84500/84460/d0284ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Lake City Lake City 7.2/10 Good (164) "Really quiet and clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Earnest CA $150 CA $168 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Florence-Hotels-Quality-Inn-Suites.h84460.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/bf604151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/8f02222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/60008f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Crossroads Lake City 9.4/10 Exceptional (802) "Need more than 1 table for continental breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $153 CA $172 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/26600/26537/44d970ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26600/26537/4d4f5623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/30000/26600/26537/193275a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26600/26537/cb6ea934.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Lake City Lake City 6.4/10 (241) "The room was really good! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olulana CA $156 CA $175 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-Lake-City.h26537.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/c7afe694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/0ea8f0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/22e67acb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area Florence 9.2/10 Wonderful (1131) "Friendly staff, clean, great location near retail, restaurants and the highway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn CA $145 CA $163 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/86912dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/90789704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 Florence 9.0/10 Wonderful (528) "Pleasant staff, clean, and a very nice breakfast with several options. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $145 CA $162 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/1e0c4eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/94a4d77a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/f287bfc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence Center Florence 9.0/10 Wonderful (799) "Front desk clerk STACY gave excellent service. All other staff and house keepers were very friendly and nice. Definitely will stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lasheba CA $134 CA $150 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, Multiple Beds](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/236a2b2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/ca4e1745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9 AM to 9 PM, pool umbrellas](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/520a38b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Florence Florence 9.0/10 Wonderful (678) "Wonderful check in, Clean and safe" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) NOELLE CA $139 CA $156 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/17df73d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/527e1e08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/6c72c859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG Florence 9.2/10 Wonderful (1002) "I would stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth CA $154 CA $173 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/bac50e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/ffb23f98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d1f8ba02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center Florence 6.8/10 (1002) "Great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sedrin CA $85 CA $96 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/1000000/330000/327200/327193/c73a2ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/330000/327200/327193/da1ecd72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/330000/327200/327193/b79560d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327200/327193/2c37ea63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Kingstree Kingstree 6.0/10 (168) "Is old but for one night is ok." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesus CA $102 CA $114 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Kingstree-Hotels-Quality-Inn-Kingstree.h327193.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-23&endDate=2025-11-24®ionId=8506&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Lake City Hotel Reviews ![The Inn at the Crossroads](//images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76_y.jpg) ### The Inn at the Crossroads 10/10 Excellent "Need more than 1 table for continental breakfast. " [](https://expedia.ca/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![SpringHill Suites by Marriott Florence](//images.trvl-media.com/lodging/1000000/980000/975000/974962/90a03799_y.jpg) ### SpringHill Suites by Marriott Florence 10/10 Excellent "Staff was very welcoming, friendly and professional. Very nice room, comfortable and clean. Great location." [](https://expedia.ca/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Home2 Suites by Hilton Florence, SC](//images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/25ce2409_y.jpg) ### Home2 Suites by Hilton Florence, SC 10/10 Excellent "The front desk service was top notch as she assisted me with getting my reservation corrected that Hotel.com messed up." [](https://expedia.ca/Florence-Hotels-Home2-Suites-By-Hilton-Florence.h7271220.Hotel-Information) ![Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG](//images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/17df73d5_y.jpg) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG 10/10 Excellent "Bed had a dip in the middle but room was clean " [](https://expedia.ca/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![TownePlace Suites by Marriott Florence](//images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg) ### TownePlace Suites by Marriott Florence 10/10 Excellent "All was well " [](https://expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Fairfield Inn & Suites by Marriott Florence I-20](//images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640_y.jpg) ### Fairfield Inn & Suites by Marriott Florence I-20 10/10 Excellent "The room was super clean. The check-in staff were super efficient considering i arrived there late in the night (11 pm). There was hot tea available when i needed. " [](https://expedia.ca/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Hampton Inn & Suites Florence Center](//images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003_y.jpg) ### Hampton Inn & Suites Florence Center 10/10 Excellent "Lovely receptionist, nice entrance hall " [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Residence Inn Marriott Florence](//images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb_y.jpg) ### Residence Inn Marriott Florence 10/10 Excellent "The in house breakfast was very good, the food tasted fresh, and the staff was very friendly and attentive. The kitchen was an unexpected pleasant surprise. We were able to cook food we had on hand for the rest of our trip instead of dining out." [](https://expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](//images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent "Room was spotless, bed extremely comfortable and staff was very helpful and courteous. Would DEFINITELY stay there again. " [](https://expedia.ca/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Lake City cost? > You can expect to pay between CA $96 and CA $175 per night for business-friendly hotels in Lake City. Top deals on stays that are suitable for work-related guests as just a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the best business-friendly hotels in Lake City? > Many corporate travellers recommend [The Inn at the Crossroads](https://www.expedia.ca/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information). This 2-stars stay offers amenities such as al fresco dining and an outdoor entertainment area. [Quality Inn & Suites](https://www.expedia.ca/Florence-Hotels-Quality-Inn-Suites.h84460.Hotel-Information) is also popular. It has a 2.5-stars rating and conveniences like blackout curtains and complimentary breakfast. You'll have your pick of multiple business-friendly hotels in Lake City that have a total average guest review rating of 8.0. ### How many business-friendly hotels are there in Lake City? > You can choose from 2 business-friendly hotels in Lake City. Whether you're searching for conveniences like meeting rooms or dependable WiFi, trust Expedia to help you find the ideal space to get the job done. ### Why book your business-friendly hotel in Lake City with Expedia? > With top amenities like meeting rooms, 24-hour room service and free WiFi, our business-friendly accommodations come with everything you'll need to get the job done — and then chill! Enter your destination and preferred travel dates and we'll help you plan the rest. ### How can I find cheap business-friendly hotels in Lake City? > Expedia can help you narrow down your search for cheap business-friendly hotels in Lake City. Look for the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work and rest comfortably, like included breakfast and free WiFi. You can also choose your budget and hotel star rating to keep costs within your price range. ### What is there to do in Lake City near my business-friendly hotel? > After you've settled into your hotel, venture out and discover the fun things Lake City has on offer. [Moore Farms Botanical Garden](https://www.expedia.ca/Moore-Farms-Botanical-Garden-Lake-City.d738169602787049472.Vacation-Attraction) is a top attraction to add to your travel itinerary. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Business Hotels in Charleston](https://www.expedia.ca/Charleston-Hotels-Business-Hotel.0-0-d179997-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in Charleston](https://www.expedia.ca/Charleston-Hotels-Green-Sustainable.0-0-d179997-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Charleston](https://www.expedia.ca/Charleston-Hotels-Hotel-With-Early-Check-In.0-0-d179997-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in Charleston](https://www.expedia.ca/Charleston-Hotels-Hotels-With-A-Lazy-River.0-0-d179997-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - [Coward Hotels](https://www.expedia.ca/Coward-Hotels.d3000353109.Travel-Guide-Hotels) - 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