Title: Book the Best BUSINESS Hotels in Lake City in 2026 | Expedia.ca [Hotels in Lake City](https://expedia.ca/Lake-City-Hotels.d6048190.Travel-Guide-Hotels)[Vacation Rentals in Lake City](https://expedia.ca/Lake-City-Vacation-Rentals.d6048190.Travel-Guide-VacationRentals)[Flights to Lake City](https://expedia.ca/Cheap-Flights-To-Lake-City.d6048190.Travel-Guide-Flights)[Lake City Car Rentals](https://expedia.ca/Car-Rentals-In-Lake-City.d6048190.Car-Rental-Guide)[Lake City Vacation Packages](https://expedia.ca/Lake-City.d6048190.Destination-Travel-Guides) ![You will not find many waterfalls in Florida. I discovered Falling Creek Falls early one morning near Lake City. Take a quick detour from I-10 to see a root-beer-colored cascade, which plummets more than 10 feet over a deep lip of limestone and flows away over limestone boulders at the bottom of a ravine. Falling Creek Falls was the site of the first settlement in this area, and a short boardwalk trail offers easy access to this scenic view.](https://images.trvl-media.com/place/6048190/543ac942-6200-46c4-b47c-c3fb63e59463.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ronald Wilson # Find Business Hotels in Lake City, FL from CA $98 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lake City Business Hotels Tonight [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=6048190&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=6048190&startDate=2025-12-11&endDate=2025-12-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6048190&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6048190&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Lake City business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/1f67a534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/fad9110f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/5b344087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/bfe0c823.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Lake City [](https://www.expedia.ca/Lake-City-Hotels-Tru-By-Hilton-Lake-City.h34865542.Hotel-Information) Lake City 9.2/10 Wonderful (1005) "Great place for a restful night when traveling. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peggy CA $139 CA $156 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Lake-City-Hotels-Tru-By-Hilton-Lake-City.h34865542.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/7f945643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/c94f1402.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/70b1f0e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/4977ae81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Lake City [](https://www.expedia.ca/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information) Lake City 9.6/10 Exceptional (1000) "We love to stop here when traveling to Orlando" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bridget CA $143 CA $161 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/a415bbca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/dc8aa87c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/1240f4d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/fb3e9b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Lake City [](https://www.expedia.ca/Lake-City-Hotels-Best-Western-Plus-Lake-City.h901396.Hotel-Information) Lake City 9.2/10 Wonderful (1007) "Staff was great and breakfast was awesome." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Derrick CA $121 CA $136 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Lake-City-Hotels-Best-Western-Plus-Lake-City.h901396.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/1d104673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/0b9cfe16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/e9ad0459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Select Comfort beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/cf4e1088.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Lake City [](https://www.expedia.ca/Lake-City-Hotels-Hampton-Inn-Suites-Lake-City.h1505814.Hotel-Information) Lake City 9.4/10 Exceptional (1000) "It was a great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miranda CA $121 CA $136 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Lake-City-Hotels-Hampton-Inn-Suites-Lake-City.h1505814.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/2886b571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/b562f911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/6a43fc6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/c38f0eff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suite by Wyndham Lake City [](https://www.expedia.ca/Lake-City-Hotels-La-Quinta-Inn-Suite-By-Wyndham-Lake-City.h48281488.Hotel-Information) Lake City 8.8/10 Excellent (1009) "Very clean property and a full hot breakfast buffet! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $130 CA $146 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Lake-City-Hotels-La-Quinta-Inn-Suite-By-Wyndham-Lake-City.h48281488.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/9a0ddc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/69fc9dfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/8207aeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/00752d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Lake City [](https://www.expedia.ca/Lake-City-Hotels-Fairfield-Inn-Suites-Lake-City.h2076513.Hotel-Information) Lake City 9.0/10 Wonderful (164) "Very clean, friendly staff, safe and quiet " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy CA $123 CA $139 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Lake-City-Hotels-Fairfield-Inn-Suites-Lake-City.h2076513.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1115400/1115327/5d9b579a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1115400/1115327/bff23b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1120000/1115400/1115327/e4437bf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1115400/1115327/7c89c912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn & Suites Lake City by IHG [](https://www.expedia.ca/Lake-City-Hotels-Holiday-Inn-Suites-Lake-City.h1115327.Hotel-Information) Lake City 8.6/10 Excellent (1000) "Dog friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara CA $115 CA $129 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Lake-City-Hotels-Holiday-Inn-Suites-Lake-City.h1115327.Hotel-Information) ![Pillowtop beds, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/17700/17650/eb9ba6b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17700/17650/529b1288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/17700/17650/8fa5709a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/17700/17650/04b1a652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Lake City I-75 [](https://www.expedia.ca/Lake-City-Hotels-Days-Inn-By-Wyndham-Lake-City-I-75.h17650.Hotel-Information) Lake City 7.6/10 Good (1000) "Clean room everything I could need staff very nice and helpful I ll be back " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daphnea CA $88 CA $98 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Lake-City-Hotels-Days-Inn-By-Wyndham-Lake-City-I-75.h17650.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/cbec2bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/494a0351.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/d203aab4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/05952e37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Lake City [](https://www.expedia.ca/Lake-City-Hotels-Quality-Inn-Lake-City.h484004.Hotel-Information) Lake City 7.8/10 Good (952) "very clean room, great staff, we will be staying there again when we come to see our daughter " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $96 CA $108 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Lake-City-Hotels-Quality-Inn-Lake-City.h484004.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25100/25013/47d0ef07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/25100/25013/0c722d95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/25100/25013/6bd91f20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25100/25013/48612482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Lake City [](https://www.expedia.ca/Lake-City-Hotels-Home2-Suites-By-Hilton-Lake-City.h25013.Hotel-Information) Lake City 9.4/10 Exceptional (733) "Great place to stay. We will be back. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $165 CA $186 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Lake-City-Hotels-Home2-Suites-By-Hilton-Lake-City.h25013.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-24&endDate=2025-12-25®ionId=6048190&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Lake City Hotel Reviews ![Best Western Plus Lake City](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/a415bbca_y.jpg) ### Best Western Plus Lake City 10/10 Excellent "Staff was so friendly and helpful. Rooms were very comfortable. " [](https://expedia.ca/Lake-City-Hotels-Best-Western-Plus-Lake-City.h901396.Hotel-Information) ![Home2 Suites by Hilton Lake City](https://images.trvl-media.com/lodging/1000000/30000/25100/25013/47d0ef07_y.jpg) ### Home2 Suites by Hilton Lake City 10/10 Excellent "Always love staying here when visiting for Gators games!!" [](https://expedia.ca/Lake-City-Hotels-Home2-Suites-By-Hilton-Lake-City.h25013.Hotel-Information) ![Baymont by Wyndham Lake City I-75](https://images.trvl-media.com/lodging/1000000/20000/15800/15747/590bae4a_y.jpg) ### Baymont by Wyndham Lake City I-75 10/10 Excellent "Chill" [](https://expedia.ca/Lake-City-Hotels-Baymont-By-Wyndham-Lake-City.h15747.Hotel-Information) ![Holiday Inn & Suites Lake City by IHG](https://images.trvl-media.com/lodging/2000000/1120000/1115400/1115327/5d9b579a_y.jpg) ### Holiday Inn & Suites Lake City by IHG 10/10 Excellent "Dog friendly. " [](https://expedia.ca/Lake-City-Hotels-Holiday-Inn-Suites-Lake-City.h1115327.Hotel-Information) ![Quality Inn Lake City](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/cbec2bb3_y.jpg) ### Quality Inn Lake City 10/10 Excellent "Hotel was under renovation but it really did not affect our stay. Breakfast was delicious, front desk staff was very friendly, courteous and helpful. " [](https://expedia.ca/Lake-City-Hotels-Quality-Inn-Lake-City.h484004.Hotel-Information) ![Americas Best Value Inn Lake City](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/1bfc5692_y.jpg) ### Americas Best Value Inn Lake City 10/10 Excellent "Room was clean & staff very friendly as well as price very affordable. " [](https://expedia.ca/Lake-City-Hotels-Americas-Best-Value-Inn-Lake-City.h1039754.Hotel-Information) ![Comfort Suites Lake City](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/7f945643_y.jpg) ### Comfort Suites Lake City 10/10 Excellent "Very nice customer service" [](https://expedia.ca/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information) ![Fairfield Inn & Suites Lake City](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/9a0ddc50_y.jpg) ### Fairfield Inn & Suites Lake City 10/10 Excellent "Everything was wonderful! We would definitely stay here again. Our favorite place so far!" [](https://expedia.ca/Lake-City-Hotels-Fairfield-Inn-Suites-Lake-City.h2076513.Hotel-Information) ![Hampton Inn & Suites Lake City](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/1d104673_y.jpg) ### Hampton Inn & Suites Lake City 10/10 Excellent "Everything was great would recommend " [](https://expedia.ca/Lake-City-Hotels-Hampton-Inn-Suites-Lake-City.h1505814.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Lake City cost? ### What are the best business-friendly hotels in Lake City? ### How many business-friendly hotels are there in Lake City? ### What are the best cheap business-friendly hotels in Lake City? ### What are the top business-friendly motels in Lake City? ### Are there any family-friendly hotels in Lake City that are also business friendly? ### Why book your business-friendly hotel in Lake City with Expedia? ### How can I find cheap business-friendly hotels in Lake City? ### What is there to do in Lake City near my business-friendly hotel? ## Explore a world of travel with Expedia - 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