Title: 10 Best Hotels in La Misión, Cajeme for 2025 | Expedia.ca [Vacation Rentals in Cajeme](https://expedia.ca/Cajeme-Vacation-Rentals.d553248635640644142.Travel-Guide-VacationRentals)[La Misión Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mision.d553248635976397316.Car-Rental-Guide)[La Misión Vacations](https://expedia.ca/La-Mision.d553248635976397316.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in La Misión, Cajeme ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in La Misión Family friendly [](https://www.expedia.ca/Hotel-Search?destination=La+Misi%C3%B3n%2C+Cajeme%2C+Sonora%2C+Mexico®ionId=553248635976397316&latLong=27.462088%2C-109.931016&adults=2&startDate=2025-11-10&d1=2025-11-10&endDate=2025-11-12&d2=2025-11-12&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=La+Misi%C3%B3n%2C+Cajeme%2C+Sonora%2C+Mexico®ionId=553248635976397316&latLong=27.462088%2C-109.931016&adults=2&startDate=2025-11-10&d1=2025-11-10&endDate=2025-11-12&d2=2025-11-12&amenities=POOL) ## Check prices for these dates Tonight [Oct 27 - Oct 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976397316&startDate=2025-10-27&endDate=2025-10-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 28 - Oct 29](https://www.expedia.ca/Hotel-Search?regionId=553248635976397316&startDate=2025-10-28&endDate=2025-10-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976397316&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976397316&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## La Misión hotels and places to stay ![Fridge, microwave, electric kettle](https://images.trvl-media.com/lodging/16000000/15370000/15362500/15362471/275f8a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15370000/15362500/15362471/ef756d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, electric kettle](https://images.trvl-media.com/lodging/16000000/15370000/15362500/15362471/ed463a2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15370000/15362500/15362471/e2ead2f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bugambilias 4.2 km from La Misión 7.6/10 Good (147) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) José María CA $27 CA $32 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Cajeme-Hotels-Hotel-Bugambilias.h15362471.Hotel-Information) ![Private pool](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/81aa329e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/f1c1eda2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/80c5befc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave | In-room dining](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/830a0143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus San Jorge 5.5 km from La Misión 8.2/10 Very good (451) "Great Place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandro CA $85 CA $101 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Cajeme-Hotels-Best-Western-Plus-San-Jorge.h1157087.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/067e97cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/b3bb3660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/9d590de2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/8f220569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ciudad Obregon by IHG 5.2 km from La Misión 9.2/10 Wonderful (665) "Great place to stay!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Deirdre CA $139 CA $165 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Cajeme-Hotels-Holiday-Inn-Express-Suites-Ciudad-Obregon.h16608238.Hotel-Information) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/8dc0b57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/5f14fda1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/43b0a95c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and lunch served, local cuisine](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/348587c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posada del Yaqui 2.7 km from La Misión 8.6/10 Excellent (114) "Breakfast very good flavor Rooms are very clean And price very afortable" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ernesto CA $45 CA $54 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Cajeme-Hotels-Hotel-Posada-Del-Yaqui.h38793110.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/b58494e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/0b86c4fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/2eddc7d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/eed13b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Napoles 4.5 km from La Misión 9.0/10 Wonderful (29) "It’s quiet, good location, service is great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) luz CA $52 CA $62 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Cajeme-Hotels-Hotel-Napoles.h35031662.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/babb2e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/2eb58887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/7be61fe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/b831f9a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Ciudad Obregón 5.6 km from La Misión 8.6/10 Excellent (819) "Clean and safe place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Blanca CA $93 CA $111 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Cajeme-Hotels-City-Express-Ciudad-Obregon.h4978633.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/0bc3be44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/f60e3b04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/ecf6ca59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/1f2bede3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden Ciudad Obregon 4 km from La Misión 8.0/10 Very good (623) "I’ve stayed two times and the front desk staff are great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $94 CA $112 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Cajeme-Hotels-Wyndham-Garden-Ciudad-Obregon.h1095160.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/cd9365ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast (MXN 250 per person)](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/5f7c9237.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/36475d6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/fd38152d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InHouse Hotel Obregón 5 km from La Misión 8.6/10 Excellent (339) "Good place to stay. Would definitely come back!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Griselda Judith CA $78 CA $92 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Cajeme-Hotels-InHouse-Obregon.h95993798.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/0bb58bd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/64f336cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/1095a01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/0ae50a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Ciudad Obregon 4.2 km from La Misión 8.0/10 Very good (571) "Awesome hotel.. really delicious food and great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria CA $79 CA $94 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Cajeme-Hotels-Quality-Inn-Ciudad-Obregon.h79114.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/b40ac3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/5b2cc606.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/4237809f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/42519cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fiesta Inn Express Ciudad Obregón 5.2 km from La Misión 8.4/10 Very good (906) "It is really clean and well located " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) rosa CA $120 CA $144 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Cajeme-Hotels-Fiesta-Inn-Ciudad-Obregon.h1764754.Hotel-Information) ![Staircase](https://images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/ac1dc85b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/66d662e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/587ce826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 2 Double Beds, Non Smoking | Balcony](https://images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/1664874a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gran Hotel Residencial Galerias 4.2 km from La Misión 8.6/10 Excellent (238) "Excelente" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Franco CA $79 CA $94 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Cajeme-Hotels-Gran-Hotel-Residencial-Galerias.h37846065.Hotel-Information) ![Free self parking](https://images.trvl-media.com/lodging/20000000/19870000/19867400/19867359/d4035551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room](https://images.trvl-media.com/lodging/20000000/19870000/19867400/19867359/291a6168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/20000000/19870000/19867400/19867359/e4bcc664.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/20000000/19870000/19867400/19867359/d100dba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Obregon 4.3 km from La Misión 6.8/10 (74) "Like" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) AxelFms CA $60 CA $71 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Cajeme-Hotels-HOTEL-OBREGON.h19867359.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/4a666242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/b35c4170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/e0d0f98b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/e4b24584.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Yori 5.3 km from La Misión 6.6/10 (161) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) JUAN CARLOS CA $64 CA $77 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Cajeme-Hotels-Hotel-Yori.h13498331.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-10&endDate=2025-11-11®ionId=553248635976397316&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mision-Cajeme-Hotels.0-n553248635976397316-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mision-Cajeme-Hotels.0-n553248635976397316-0.Travel-Guide-Filter-Hotels) ## Top guest rated hotels in La Misión ![Exterior](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/067e97cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/b3bb3660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/9d590de2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/8f220569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ciudad Obregon by IHG 5.2 km from La Misión 9.2/10 Wonderful (665) CA $139 CA $165 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16&selected=16608238&PinnedHotelID=16608238&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) ![Private pool](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/81aa329e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/f1c1eda2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/80c5befc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave | In-room dining](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/830a0143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus San Jorge 5.5 km from La Misión 8.2/10 Very good (451) CA $85 CA $101 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04&selected=1157087&PinnedHotelID=1157087&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/b40ac3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/5b2cc606.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/4237809f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/42519cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fiesta Inn Express Ciudad Obregón 5.2 km from La Misión 8.4/10 Very good (906) CA $120 CA $144 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16&selected=1764754&PinnedHotelID=1764754&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/0bc3be44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/f60e3b04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/ecf6ca59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/1f2bede3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden Ciudad Obregon 4 km from La Misión 8.0/10 Very good (623) CA $94 CA $112 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30&selected=1095160&PinnedHotelID=1095160&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) ![Lobby](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/babb2e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/2eb58887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/7be61fe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/b831f9a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Ciudad Obregón 5.6 km from La Misión 8.6/10 Excellent (819) CA $93 CA $111 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-31&endDate=2025-11-01&selected=4978633&PinnedHotelID=4978633&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/cd9365ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast (MXN 250 per person)](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/5f7c9237.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/36475d6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/fd38152d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InHouse Hotel Obregón 5 km from La Misión 8.6/10 Excellent (339) CA $78 CA $92 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03&selected=95993798&PinnedHotelID=95993798&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/0bb58bd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/64f336cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/1095a01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/0ae50a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Ciudad Obregon 4.2 km from La Misión 8.0/10 Very good (571) CA $79 CA $94 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03&selected=79114&PinnedHotelID=79114&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) ![Front of property](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/b58494e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/0b86c4fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/2eddc7d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/eed13b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Napoles 4.5 km from La Misión 9.0/10 Wonderful (29) CA $52 CA $62 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-28&endDate=2025-10-29&selected=35031662&PinnedHotelID=35031662&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) ![Staircase](https://images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/ac1dc85b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/66d662e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/587ce826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 2 Double Beds, Non Smoking | Balcony](https://images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/1664874a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gran Hotel Residencial Galerias 4.2 km from La Misión 8.6/10 Excellent (238) CA $79 CA $94 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-28&endDate=2025-10-29&selected=37846065&PinnedHotelID=37846065&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/8dc0b57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/5f14fda1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/43b0a95c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and lunch served, local cuisine](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/348587c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posada del Yaqui 2.7 km from La Misión 8.6/10 Excellent (114) CA $45 CA $54 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-28&endDate=2025-10-29&selected=38793110&PinnedHotelID=38793110&HadPinnedHotel=true®ionId=553248635976397316&adults=2&guestRating=35&openPlayBack=true) [See more properties](https://www.expedia.ca/Hotel-Search?startDate=2025-11-10&endDate=2025-11-11®ionId=553248635976397316&adults=2&sort=RECOMMENDED&guestRating=35&openPlayBack=true) ## Where to stay in La Misión Find the best La Misión areas and neighborhoods for the activities you enjoy most. - Parque Industrial [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=636353632370581504) ![Parque Industrial map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:scvfDrt%7C%7DSsO%3Fu%40alCr_BG%7D%40jO%60MhKmyAroB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=k9iq93w5VJF9SGgkrQp-V2zIgjQ=) ### Parque Industrial Though Parque Industrial might not have many top sights, you can venture to the surrounding area to see attractions like Sendero Plaza and H. Cajeme Town Hall. [See properties](https://www.expedia.ca/Hotel-Search?regionId=636353632370581504) ## Top La Misión Hotel Reviews ![Holiday Inn Express & Suites Ciudad Obregon by IHG](//images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/067e97cf_y.jpg) ### Holiday Inn Express & Suites Ciudad Obregon by IHG 10/10 Excellent "They need more parking " [](https://expedia.ca/Cajeme-Hotels-Holiday-Inn-Express-Suites-Ciudad-Obregon.h16608238.Hotel-Information) ![Quality Inn Ciudad Obregon](//images.trvl-media.com/lodging/1000000/80000/79200/79114/0bb58bd1_y.jpg) ### Quality Inn Ciudad Obregon 10/10 Excellent "Clean room and bar" [](https://expedia.ca/Cajeme-Hotels-Quality-Inn-Ciudad-Obregon.h79114.Hotel-Information) ![Best Western Plus San Jorge](//images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/81aa329e_y.jpg) ### Best Western Plus San Jorge 10/10 Excellent "This hotel has been a part of Cajeme for at least 60 to 70 years and is still well-run and thriving. It offers easy access to Interstate 15 and is conveniently located near downtown and the historic town of Cocorit, which features a charming church built in 1617, as well as wonderful restaurants. BEST OF ALL IT ACCEPTS PETS" [](https://expedia.ca/Cajeme-Hotels-Best-Western-Plus-San-Jorge.h1157087.Hotel-Information) ![InHouse Hotel Obregón](//images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/cd9365ed_y.jpg) ### InHouse Hotel Obregón 10/10 Excellent "Staff friendly Isabel on the lobby, on the restaurant the security guard everyone so friendly thanks I will be back . My room was clean and welcome letter thanks !!!!" [](https://expedia.ca/Cajeme-Hotels-InHouse-Obregon.h95993798.Hotel-Information) ![Gran Hotel Residencial Galerias](//images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/ac1dc85b_y.jpg) ### Gran Hotel Residencial Galerias 10/10 Excellent "." [](https://expedia.ca/Cajeme-Hotels-Gran-Hotel-Residencial-Galerias.h37846065.Hotel-Information) ![Wyndham Garden Ciudad Obregon](//images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/0bc3be44_y.jpg) ### Wyndham Garden Ciudad Obregon 10/10 Excellent "Pool was a mess and the light fixture hanging out" [](https://expedia.ca/Cajeme-Hotels-Wyndham-Garden-Ciudad-Obregon.h1095160.Hotel-Information) ![City Express by Marriott Ciudad Obregón](//images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/babb2e31_y.jpg) ### City Express by Marriott Ciudad Obregón 10/10 Excellent "Friendly staff " [](https://expedia.ca/Cajeme-Hotels-City-Express-Ciudad-Obregon.h4978633.Hotel-Information) ![Hotel Yori](//images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/4a666242_y.jpg) ### Hotel Yori 10/10 Excellent "Exelent attention end service" [](https://expedia.ca/Cajeme-Hotels-Hotel-Yori.h13498331.Hotel-Information) ![Hotel Napoles](//images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/b58494e1_y.jpg) ### Hotel Napoles 10/10 Excellent "It’s quiet, good location, service is great." [](https://expedia.ca/Cajeme-Hotels-Hotel-Napoles.h35031662.Hotel-Information) ## Frequently asked questions ### What is La Misión like? > Travelers will be sure to find plenty to entertain them in Ciudad Obregón's La Misión neighborhood. ### If I need to cancel my hotel reservation in La Misión, will I receive a refund? > Yes, the majority of hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to review the best deals available in La Misión. ### What is there to do around this Ciudad Obregón neighborhood? > A few places to visit in the area around La Misión include Sendero Plaza, Galería de Arte ITSON, and Plaza Bella Vista. When you're sightseeing in Ciudad Obregón, H. Cajeme Town Hall and Plaza Tutuli Shopping Center are also worth a stop. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Alamos Hotels](https://www.expedia.ca/Alamos-Hotels.d10491.Travel-Guide-Hotels) - [Lgbt Friendly Hotels in Cajeme](https://www.expedia.ca/Cajeme-Hotels-LGBT-Friendly-Hotel.0-0-d553248635640644142-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Cajeme Hotels](https://www.expedia.ca/Cajeme-Hotels.d553248635640644142.Travel-Guide-Hotels) - [Centro Guaymas Hotels](https://www.expedia.ca/Centro-Guaymas-Guaymas-Hotels.0-n655532267611185152-0.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Ciudad Obregón](https://www.expedia.ca/Ciudad-Obregon-Hotels-Pet-Friendly-Hotel.0-0-d806-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Ciudad Obregón Hotels](https://www.expedia.ca/Ciudad-Obregon-Hotels.d806.Travel-Guide-Hotels) - [Cócorit Hotels](https://www.expedia.ca/Cocorit-Hotels.d553248635998002074.Travel-Guide-Hotels) - 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