Title: 10 Best Hotels in La Misión, Cajeme for 2025 | Expedia.ca [Vacation Rentals in Cajeme](https://expedia.ca/Cajeme-Vacation-Rentals.d553248635640644142.Travel-Guide-VacationRentals)[La Misión Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mision.d553248635976397316.Car-Rental-Guide)[La Misión Vacations](https://expedia.ca/La-Mision.d553248635976397316.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in La Misión, Cajeme ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in La Misión Family friendly [](https://www.expedia.ca/Hotel-Search?destination=La+Misi%C3%B3n%2C+Cajeme%2C+Sonora%2C+Mexico®ionId=553248635976397316&latLong=27.462088%2C-109.931016&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=La+Misi%C3%B3n%2C+Cajeme%2C+Sonora%2C+Mexico®ionId=553248635976397316&latLong=27.462088%2C-109.931016&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&amenities=POOL) ## Check prices for these dates Tonight [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976397316&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=553248635976397316&startDate=2025-09-28&endDate=2025-09-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976397316&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976397316&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## La Misión hotels and places to stay ![Fridge, microwave, electric kettle](https://images.trvl-media.com/lodging/16000000/15370000/15362500/15362471/275f8a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15370000/15362500/15362471/e2ead2f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15370000/15362500/15362471/ef756d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, electric kettle](https://images.trvl-media.com/lodging/16000000/15370000/15362500/15362471/41e19a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bugambilias 4.2 km from La Misión 7.6/10 Good (143) "Excelente " CA $27 CA $32 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Cajeme-Hotels-Hotel-Bugambilias.h15362471.Hotel-Information) ![Private pool](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/81aa329e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/80c5befc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave | In-room dining](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/830a0143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine, alfresco dining ](https://images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/120dfddc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus San Jorge 5.5 km from La Misión 8.2/10 Very good (444) "Nice place " CA $87 CA $104 total includes taxes & fees Oct 3 - Oct 4 [](https://www.expedia.ca/Cajeme-Hotels-Best-Western-Plus-San-Jorge.h1157087.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/067e97cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/039b94a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/9d590de2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/8f220569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ciudad Obregon by IHG 5.2 km from La Misión 9.2/10 Wonderful (653) "Great place to stay!" CA $121 CA $144 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Cajeme-Hotels-Holiday-Inn-Express-Suites-Ciudad-Obregon.h16608238.Hotel-Information) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/8dc0b57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and lunch served, local cuisine](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/348587c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/5f14fda1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38800000/38793200/38793110/43b0a95c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posada del Yaqui 2.7 km from La Misión 8.6/10 Excellent (113) "Breakfast very good flavor Rooms are very clean And price very afortable" CA $43 CA $51 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Cajeme-Hotels-Hotel-Posada-Del-Yaqui.h38793110.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/b58494e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/0b86c4fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/2eddc7d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/4d1d8206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Napoles 4.5 km from La Misión 9.0/10 Wonderful (28) "It’s quiet, good location, service is great." CA $52 CA $62 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Cajeme-Hotels-Hotel-Napoles.h35031662.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/babb2e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/7be61fe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/b831f9a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/w4000h2662x0y0-386c4420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Ciudad Obregón 5.6 km from La Misión 8.6/10 Excellent (812) "I would definitely stay here again." CA $89 CA $106 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Cajeme-Hotels-City-Express-Ciudad-Obregon.h4978633.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/0bc3be44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/3154cd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/ecf6ca59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/1f2bede3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden Ciudad Obregon 4 km from La Misión 8.0/10 Very good (615) "Very clean, quiet and great breakfast. " CA $86 CA $102 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Cajeme-Hotels-Wyndham-Garden-Ciudad-Obregon.h1095160.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/cd9365ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/fd38152d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/36475d6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/5ff82e4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InHouse Hotel Obregón 5 km from La Misión 8.6/10 Excellent (327) "Staff friendly Isabel on the lobby, on the restaurant the security guard everyone so friendly thanks I will be back . My room was clean and welcome letter thanks !!!!" CA $73 CA $87 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Cajeme-Hotels-InHouse-Obregon.h95993798.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/0bb58bd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/da141dbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/0ae50a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/80000/79200/79114/1095a01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Ciudad Obregon 4.2 km from La Misión 8.0/10 Very good (567) "Awesome hotel.. really delicious food and great location" CA $82 CA $98 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Cajeme-Hotels-Quality-Inn-Ciudad-Obregon.h79114.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/b40ac3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/4237809f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/4b0088c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1770000/1764800/1764754/42519cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fiesta Inn Express Ciudad Obregón 5.2 km from La Misión 8.4/10 Very good (900) "It is really clean and well located " CA $137 CA $163 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Cajeme-Hotels-Fiesta-Inn-Ciudad-Obregon.h1764754.Hotel-Information) ![Free self parking](https://images.trvl-media.com/lodging/20000000/19870000/19867400/19867359/d4035551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/20000000/19870000/19867400/19867359/e4bcc664.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/20000000/19870000/19867400/19867359/d100dba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room](https://images.trvl-media.com/lodging/20000000/19870000/19867400/19867359/291a6168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Obregon 4.3 km from La Misión 6.8/10 (74) "Like" CA $60 CA $71 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Cajeme-Hotels-HOTEL-OBREGON.h19867359.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/4a666242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/2f20e65c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/b35c4170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/e4b24584.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Yori 5.3 km from La Misión 6.6/10 (159) "Excelente " CA $55 CA $65 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Cajeme-Hotels-Hotel-Yori.h13498331.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-11&endDate=2025-10-12®ionId=553248635976397316&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in La Misión Find the best La Misión areas and neighborhoods for the activities you enjoy most. - Parque Industrial [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=636353632370581504) ![Parque Industrial map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:scvfDrt%7C%7DSsO%3Fu%40alCr_BG%7D%40jO%60MhKmyAroB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=k9iq93w5VJF9SGgkrQp-V2zIgjQ=) ### Parque Industrial Though Parque Industrial might not have many top sights, you can venture to the surrounding area to see attractions like Sendero Plaza and H. Cajeme Town Hall. [See properties](https://www.expedia.ca/Hotel-Search?regionId=636353632370581504) ## Top La Misión Hotel Reviews ![InHouse Obregón](//images.trvl-media.com/lodging/96000000/96000000/95993800/95993798/cd9365ed_y.jpg) ### InHouse Obregón 10/10 Excellent "Staff friendly Isabel on the lobby, on the restaurant the security guard everyone so friendly thanks I will be back . My room was clean and welcome letter thanks !!!!" [](https://expedia.ca/Cajeme-Hotels-InHouse-Obregon.h95993798.Hotel-Information) ![Best Western Plus San Jorge](//images.trvl-media.com/lodging/2000000/1160000/1157100/1157087/81aa329e_y.jpg) ### Best Western Plus San Jorge 10/10 Excellent "Nice place " [](https://expedia.ca/Cajeme-Hotels-Best-Western-Plus-San-Jorge.h1157087.Hotel-Information) ![Holiday Inn Express & Suites Ciudad Obregon by IHG](//images.trvl-media.com/lodging/17000000/16610000/16608300/16608238/067e97cf_y.jpg) ### Holiday Inn Express & Suites Ciudad Obregon by IHG 10/10 Excellent "I have been staying at this hotel/ location over the past 3-4 years, multiple times.. in my humble opinion, it is the best option in Ciudad Obregon " [](https://expedia.ca/Cajeme-Hotels-Holiday-Inn-Express-Suites-Ciudad-Obregon.h16608238.Hotel-Information) ![Gran Hotel Residencial Galerias](//images.trvl-media.com/lodging/38000000/37850000/37846100/37846065/ac1dc85b_y.jpg) ### Gran Hotel Residencial Galerias 10/10 Excellent "." [](https://expedia.ca/Cajeme-Hotels-Gran-Hotel-Residencial-Galerias.h37846065.Hotel-Information) ![Wyndham Garden Ciudad Obregon](//images.trvl-media.com/lodging/2000000/1100000/1095200/1095160/0bc3be44_y.jpg) ### Wyndham Garden Ciudad Obregon 10/10 Excellent "Pool was a mess and the light fixture hanging out" [](https://expedia.ca/Cajeme-Hotels-Wyndham-Garden-Ciudad-Obregon.h1095160.Hotel-Information) ![City Express by Marriott Ciudad Obregón](//images.trvl-media.com/lodging/5000000/4980000/4978700/4978633/babb2e31_y.jpg) ### City Express by Marriott Ciudad Obregón 10/10 Excellent "Friendly staff " [](https://expedia.ca/Cajeme-Hotels-City-Express-Ciudad-Obregon.h4978633.Hotel-Information) ![Hotel Yori](//images.trvl-media.com/lodging/14000000/13500000/13498400/13498331/4a666242_y.jpg) ### Hotel Yori 10/10 Excellent "Exelent attention end service" [](https://expedia.ca/Cajeme-Hotels-Hotel-Yori.h13498331.Hotel-Information) ![Quality Inn Ciudad Obregon](//images.trvl-media.com/lodging/1000000/80000/79200/79114/0bb58bd1_y.jpg) ### Quality Inn Ciudad Obregon 10/10 Excellent "This place is a good to stay but neded up grades. " [](https://expedia.ca/Cajeme-Hotels-Quality-Inn-Ciudad-Obregon.h79114.Hotel-Information) ![Hotel Napoles](//images.trvl-media.com/lodging/36000000/35040000/35031700/35031662/b58494e1_y.jpg) ### Hotel Napoles 10/10 Excellent "It’s quiet, good location, service is great." 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