Title: La Mesilla Guest Houses from CA $98 | Expedia.ca [Hotels in La Mesilla](https://expedia.ca/La-Mesilla-Hotels.d553248635975872198.Travel-Guide-Hotels)[Vacation Rentals in La Mesilla](https://expedia.ca/La-Mesilla-Vacation-Rentals.d553248635975872198.Travel-Guide-VacationRentals)[La Mesilla Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesilla.d553248635975872198.Car-Rental-Guide)[La Mesilla Vacation Packages](https://expedia.ca/La-Mesilla.d553248635975872198.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in La Mesilla from CA $98 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635975872198&startDate=2025-12-19&endDate=2025-12-21&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635975872198&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635975872198&startDate=2026-01-09&endDate=2026-01-11&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635975872198&startDate=2026-02-06&endDate=2026-02-08&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select La Mesilla Guest Houses No exact matches found, but these alternatives could be just right ## Recommended hotels in La Mesilla ![Suite, 1 King Bed | View from room](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/c6ba74ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/ebfa22d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/866cf9af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, dinner served](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/d2f37750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Santa Fe Buffalo Thunder Santa Fe 8.6/10 Excellent (1008) "The staff checking us in were great! Friendly and made us feel welcomed!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cherise CA $142 CA $162 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Santa-Fe-Hotels-Hilton-Santa-Fe-Buffalo-Thunder.h2058957.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/a25f16f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/w797h532x3y3-17b34bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Casita](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/217a360e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Kiva Room](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/f8395467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Escondida Bed & Breakfast Chimayo 9.4/10 Exceptional (262) "Beautiful historic property. Great staff and excellent breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $164 CA $183 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Santa-Fe-Hotels-Casa-Escondida-Bed-Breakfast.h521375.Hotel-Information) ![Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/912a4f46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/39bddef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/ca9f58d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/6d04c5f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Glorieta Santa Fe 8.0/10 Very good (39) "Loved the decor" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marian CA $131 CA $190 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Hotel-Glorieta.h3139.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/4dd42a18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/a14f1c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathroom sink](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/a406f7fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/112d7b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cities Of Gold Casino Santa Fe 8.0/10 Very good (1068) "Always love staying here everything was good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rafael CA $85 CA $98 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Cities-Of-Gold-Casino.h120761.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/5368dc35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/8e5c8563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/c7bcc3f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/5b9132ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ohkay Casino Resort Hotel Ohkay Owingeh 8.0/10 Very good (787) "Clean rooms and excellent service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patrick [](https://www.expedia.ca/Santa-Fe-Hotels-Ohkay-Casino-Resort-Hotel.h458023.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/eb9982cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, body treatments, hot stone massages](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/459f0ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/753685a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/06dccf6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Resort Rancho Encantado Santa Fe Santa Fe 9.4/10 Exceptional (265) "Food options were good, but limited. The scenery was breathtaking as well as the nearby Santa Fe and the tours we took to the Indian reservation and Los Alamos" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ILAN CA $718 CA $892 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Santa-Fe-Hotels-Four-Seasons-Resort-Rancho-Encantado-Santa-Fe.h40731.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/a0789287.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/4d99e8b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV, fireplace](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/6861e853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/47f356a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Delta Espanola 9.4/10 Exceptional (1001) "The room was very clean with plenty of space. Nice and quiet area. Really enjoyed our 3 night stay." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Taco [](https://www.expedia.ca/Santa-Fe-Hotels-The-Inn-At-The-Delta.h1581298.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/dc73db0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/93204597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Kiva) | Bathroom](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/bba54b63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Bunkhouse)](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/807aba16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bishop's Lodge, Auberge Collection Tesuque 9.4/10 Exceptional (88) "Great location, Resort, amenities, excellent service and great restaurant chef!!!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James R [](https://www.expedia.ca/Santa-Fe-Hotels-Bishops-Lodge.h40737.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/97badd85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/fa5fca8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/e09560b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking (Multi-level) | Living area](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/cbf589c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Santa Fe-North Santa Fe 9.2/10 Wonderful (1001) "Good breakfast, clean, staff friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KIMTHU CA $164 CA $187 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Homewood-Suites-By-Hilton-Santa-Fe-North.h1184592.Hotel-Information) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/7c97c173.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/8eb880ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/4611a00b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/e5b066f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham Los Alamos Los Alamos 8.0/10 Very good (569) "Solid hotel with very friendly and supportive staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Markus CA $104 CA $116 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Comfort-Inn-Suites-Los-Alamos.h74653.Hotel-Information) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/e0f972f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/9536bd31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/ef74e67b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/18384ff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Española Espanola 6.2/10 (466) "Friendly staff, clean on the surface, appears to be in renovation stage, heat and air worked fine, lighted/fenced parking, filthy sheets, cigarette burned bed covers, no (soap, shampoo, conditioner, hair dryer), and breakfast was just coffee and oatmeal packets. This place is perfect as a homeless refuge or a 1 hour rental. Do yourself a favor and stay at one of the local casinos." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) M L CA $99 CA $113 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Santa-Fe-Hotels-Rodeway-Inn.h16124.Hotel-Information) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/4901e7b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/007ac679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/b013eb88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/989192ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Los Alamos White Rock Los Alamos 9.0/10 Wonderful (674) "Nice place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura CA $154 CA $172 total includes taxes & fees Jan 6 - Jan 7, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Hampton-Inn-Suites-Los-Alamos-White-Rock.h908632.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96490000/96484300/96484233/dcce70a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/97000000/96490000/96484300/96484233/9cbed719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, stereo](https://images.trvl-media.com/lodging/97000000/96490000/96484300/96484233/59e48979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/97000000/96490000/96484300/96484233/0dfb8444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tesuque Outpost |Casita E | Best views in Santa Fe Tesuque 9.8/10 Exceptional (10) "CleanBeautiful ViewsQuite" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debbie B. CA $112 CA $331 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Santa-Fe-Hotels-Tesuque-Outpost-Suite-E-Mountain-Views.h96484233.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/65b278ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/cc65f258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/c25e2986.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/08467533.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Los Alamos Entrada Park by IHG Los Alamos 8.8/10 Excellent (741) "The room was spotless , all the employees are friendly and have great customer service. The breakfast is really good . " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Claudia CA $155 CA $174 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Santa-Fe-Hotels-Holiday-Inn-Express-Hotel-Suites-Los-Alamos.h2976403.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/96f30ddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/d273fba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/3fabc09c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/317dd2ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Espanola, NM Espanola 6.4/10 (517) "One of the cleanest motels I’ve been in a long time. The water was hot. It was good and they provided coffee. I will definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sally CA $123 CA $140 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Motel-6-Espanola.h459557.Hotel-Information) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92460000/92452100/92452058/w1024h679x0y2-b2771782.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92460000/92452100/92452058/08ededaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/93000000/92460000/92452100/92452058/w1024h680x0y0-bce8cffc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/93000000/92460000/92452100/92452058/2490085d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peaceful Suite in Desert Inn- Acoma Queen Room Ojo Caliente 9.4/10 Exceptional (6) "Cannot recommend this place highly enough. Comfortable and very well appointed with a GORGEOUS view. Get the room service….you will not regret it." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn M. CA $228 CA $328 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Ojo-Caliente-Hotels-Peaceful-Suite-In-Desert-Inn-Acoma-Queen-Room.h92452058.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119610000/119601500/119601479/e9db6663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/120000000/119610000/119601500/119601479/b0603c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119610000/119601500/119601479/7094dddb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119610000/119601500/119601479/9f79b5a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centrally-located, sweeping mountain views! Española 10/10 Exceptional (5) CA $187 CA $321 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Espanola-Hotels-Centrally-Located-Home-In-Beautiful.h119601479.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/c2604840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/bd87a46b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/59a04f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/d37475b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Espanola Espanola 5.8/10 (587) "Good place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sergio CA $143 CA $162 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Days-Inn-By-Wyndham-Espanola.h19678.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/32000000/31380000/31374500/31374449/1d964f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/32000000/31380000/31374500/31374449/192e1733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/32000000/31380000/31374500/31374449/5c8790c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/32000000/31380000/31374500/31374449/75c3916f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gorgeous Condo Near Historic Santa Fe Plaza! Casa Solana 9.8/10 Exceptional (59) "Clean and nice, would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randy C. CA $155 CA $378 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Santa-Fe-Hotels-Gorgeous-Condo-Near-Historic-Santa-Fe-Plaza.h31374449.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99400000/99393700/99393656/5fe8c381.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, foosball, books](https://images.trvl-media.com/lodging/100000000/99400000/99393700/99393656/3988c734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/100000000/99400000/99393700/99393656/51c7e9c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/100000000/99400000/99393700/99393656/a5ea9e87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Plaza Oasis Within Walking Distance, King Bed,Office,Foosball Casa Solana 9.2/10 Wonderful (5) "The fresh flowers and bottle of wine were the perfect start to a long weekend stay. Easy to relax and enjoy family time. Thanks again Casa Salano." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maureen M. CA $218 CA $495 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Santa-Fe-Hotels-Historic-Plaza-Oasis-5-Away.h99393656.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-23&endDate=2025-12-24®ionId=553248635975872198&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesilla-Guest-Houses.d553248635975872198-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesilla-Guest-Houses.d553248635975872198-aaGuestHouses.Travel-Guide-Accommodation) ## Top La Mesilla Hotel Reviews ![Cities Of Gold Casino](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/4dd42a18_y.jpg) ### Cities Of Gold Casino 10/10 Excellent "Always love staying here everything was good" [](https://expedia.ca/Santa-Fe-Hotels-Cities-Of-Gold-Casino.h120761.Hotel-Information) ![Hilton Santa Fe Buffalo Thunder](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/c6ba74ab_y.jpg) ### Hilton Santa Fe Buffalo Thunder 10/10 Excellent "Our room had an old desk chair that looked like it had been there since the hotel opened. The shower had hair in the drain and there was hair on the shower door and on the shower wall-YUCK!!!" [](https://expedia.ca/Santa-Fe-Hotels-Hilton-Santa-Fe-Buffalo-Thunder.h2058957.Hotel-Information) ![Authentic Santa Fe Casita with Views on the Edge of Town](https://images.trvl-media.com/lodging/28000000/27120000/27118000/27117946/1d09664b_y.jpg) ### Authentic Santa Fe Casita with Views on the Edge of Town 10/10 Excellent "The casita was the perfect place for my family of 4 and our Dobie. Loved the fenced in yard for the pup and the picnic table and porch were beautiful places to hang out and enjoy some Santa Fe sun! Location was great. Very short drive to the plaza. The hosts were super nice and even brought over firewood for the kiva. Oh yeah, We also enjoyed the wine left for us upon arrival! Perfect place! " [](https://expedia.ca/Santa-Fe-Hotels-Authentic-Santa-Fe-Casita-With-Views-On-The-Edge-Of-Town.h27117946.Hotel-Information) ![Wingate by Wyndham Los Alamos](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/e5b066f8_y.jpg) ### Wingate by Wyndham Los Alamos 10/10 Excellent "it was great would return staff was very helpful" [](https://expedia.ca/Santa-Fe-Hotels-Comfort-Inn-Suites-Los-Alamos.h74653.Hotel-Information) ![Ohkay Casino Resort Hotel](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/5368dc35_y.jpg) ### Ohkay Casino Resort Hotel 10/10 Excellent "Clean room" [](https://expedia.ca/Santa-Fe-Hotels-Ohkay-Casino-Resort-Hotel.h458023.Hotel-Information) ![Homewood Suites by Hilton Santa Fe-North](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/97badd85_y.jpg) ### Homewood Suites by Hilton Santa Fe-North 10/10 Excellent "Cozy, clean suite. Loved breakfast and all the amenities." [](https://expedia.ca/Santa-Fe-Hotels-Homewood-Suites-By-Hilton-Santa-Fe-North.h1184592.Hotel-Information) ![Hotel Glorieta](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/912a4f46_y.jpg) ### Hotel Glorieta 10/10 Excellent "W" [](https://expedia.ca/Santa-Fe-Hotels-Hotel-Glorieta.h3139.Hotel-Information) ![Holiday Inn Express & Suites Los Alamos Entrada Park by IHG](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/65b278ef_y.jpg) ### Holiday Inn Express & Suites Los Alamos Entrada Park by IHG 10/10 Excellent "Very accommodating Dryers in the laundry facility under repair. Front desk team invited me to dry my laundry on the big dryer used by housekeeping. Very helpful. Also heated pool and wonderful hot tub. And cookies!!" [](https://expedia.ca/Santa-Fe-Hotels-Holiday-Inn-Express-Hotel-Suites-Los-Alamos.h2976403.Hotel-Information) ![The Inn at the Delta](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/a0789287_y.jpg) ### The Inn at the Delta 10/10 Excellent "Awesome experience overall" [](https://expedia.ca/Santa-Fe-Hotels-The-Inn-At-The-Delta.h1581298.Hotel-Information) ## Find out more about La Mesilla ## La Mesilla Guest Houses information | Number of reviews | 9,023 | | ----------------- | -------------- | | Accommodation | 9 Guest Houses | | Lowest Price | CA $98 | | Highest Price | CA $892 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in El Valle de Arroyo Seco ](https://www.expedia.ca/5Star-El-Valle-De-Arroyo-Seco-Hotels.s50-0-d553248634983124254.Travel-Guide-Filter-Hotels) - [Alcalde Hotels ](https://www.expedia.ca/Alcalde-Hotels.d3000421609.Travel-Guide-Hotels) - [B&B in Chimayo ](https://www.expedia.ca/Chimayo-Bed-And-Breakfast.d89282-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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