Title: Book the Best La Mesa LUXURY Hotels - Upscale Hotels in La Mesa, CA | Expedia.ca [Hotels in La Mesa](https://expedia.ca/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Vacation Rentals in La Mesa](https://expedia.ca/La-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals)[Flights to La Mesa](https://expedia.ca/Cheap-Flights-To-La-Mesa.d8484.Travel-Guide-Flights)[La Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesa.d8484.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.ca/La-Mesa.d8484.Destination-Travel-Guides) ![View from Mount Helix, in La Mesa, near San Diego, California](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on La Mesa Luxury Hotels Tonight [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-02-05&endDate=2026-02-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-02-06&endDate=2026-02-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for La Mesa luxury hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/aa7dcb3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/2c6b815f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/6141f13c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/2639daee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus La Mesa San Diego [](https://www.expedia.ca/La-Mesa-Hotels-Best-Western-Plus-La-Mesa-San-Diego.h20454.Hotel-Information) La Mesa 8.4/10 Very good (1,003 reviews) "Yes very clean and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorraine CA $162 CA $178 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/La-Mesa-Hotels-Best-Western-Plus-La-Mesa-San-Diego.h20454.Hotel-Information) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/879c7f28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/be7ed53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/106443b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/ef7518eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 La Mesa, CA [](https://www.expedia.ca/La-Mesa-Hotels-Motel-6-La-Mesa.h565024.Hotel-Information) La Mesa 7.2/10 Good (1,002 reviews) "Very nice room. No shampoo but soap was good. Close to hospital." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Betsy [](https://www.expedia.ca/La-Mesa-Hotels-Motel-6-La-Mesa.h565024.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/879bd035.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/8cf8ea27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/d5d4acc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/471e273e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn La Mesa [](https://www.expedia.ca/La-Mesa-Hotels-Heritage-Inn-La-Mesa.h2811010.Hotel-Information) La Mesa 7.0/10 Good (1,265 reviews) "Very friendly at front desk I wish it was a little cheaper and I would stay the whole trip here" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Haley CA $79 CA $87 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/La-Mesa-Hotels-Heritage-Inn-La-Mesa.h2811010.Hotel-Information) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/7e38424e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/2d1e06fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/f398a60c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/32e4e5fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express La Mesa Near SDSU by IHG [](https://www.expedia.ca/La-Mesa-Hotels-Holiday-Inn-La-Mesa.h26924.Hotel-Information) San Diego 8.2/10 Very good (475 reviews) "Great Stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jazmin CA $190 CA $209 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/La-Mesa-Hotels-Holiday-Inn-La-Mesa.h26924.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20®ionId=8484&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top La Mesa Hotel Reviews ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Room was very clean and luxurious " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Fast Room Service " [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Bahia Resort Hotel](https://images.trvl-media.com/lodging/1000000/20000/18300/18241/86eea647_y.jpg) ### Bahia Resort Hotel 10/10 Excellent "All the staff goes out of their way, the resort is in the middle of everything. No need to drive out. So many delicious restaurants in and close. The rooms were perfect. We enjoyed every minute there " [](https://expedia.ca/San-Diego-Hotels-Bahia-Resort-Hotel.h18241.Hotel-Information) ![Paradise Point Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/bc1e5add_y.jpg) ### Paradise Point Resort & Spa 10/10 Excellent "Beautiful place, clean room excellent staff. The pools are so lovely!" [](https://expedia.ca/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) ![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "Rooms were clean, the beds were soo comfy, and staff was nice. " [](https://expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Staff was polite, rooms were clean, atmosphere was great being close to little Italy, easy access to restaurants and stores and close to the Bay Area" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 10/10 Excellent "The Best Western than seven seas is special to me because I stayed there as a child with my parents and grandparents. It is old motor in style San Diego or best Western in its old form.. The staff is great and it has a nice pool and Jacuzzi.. It is very affordable.. " [](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "This place was really nice and cozy. Friendly staff. The only thing I didn’t like was we had to pay $35 per car for parking. " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Always fabulous! That’s a great staff here, the views are wonderful, the restaurant is great, the bar is fun and the bartenders are wonderful. There’s the sweetest lady in the mornings that helps with breakfast and her name is Mariam and she is the best. I always love my stay here. " [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ## Frequently asked questions ### Which area of La Mesa is best to stay in for luxury hotels? > This neighbourhood is the historic heart of La Mesa, known for its pedestrian-friendly layout and a collection of independent shops, restaurants, and cafes. You'll find a relaxed, small-town atmosphere here, with events like the weekly farmers' market adding to its local appeal. The area is easily walkable, making it convenient to explore on foot. > > > Couples looking for a refined getaway will appreciate this location. The boutique hotels and upscale dining options in La Mesa Village offer a more intimate and personalised experience compared to larger, more generic hotels. You can enjoy strolls along La Mesa Boulevard, discover unique local businesses, and relax in a setting that feels distinctly Californian. > > > For solo travellers who appreciate quality and convenience, staying in or near La Mesa Village is also an excellent option. The area provides easy access to public transport, including the trolley, making it simple to explore wider San Diego without needing a car. ### How much does a luxury hotel in La Mesa cost? ### What luxury activities and experiences are there in La Mesa? > This area is generally quiet and well-maintained, providing a comfortable base for visitors. You'll find a selection of upscale hotels that often feature amenities like high-end fitness equipment and pools. The Grossmont Centre itself is a large outdoor shopping centre with a variety of well-known retailers and dining establishments, great for those who enjoy a bit of retail therapy or a nice meal out. > > > Couples looking for a refined getaway will appreciate the proximity to several excellent golf courses, such as the Cottonwood Golf Club, which offers a picturesque setting for a round of golf. After a day on the greens, you can enjoy a gourmet meal at one of the upscale restaurants within easy reach, many of which focus on fresh, local ingredients. > > > Those seeking wellness and relaxation will find several high-quality spas and wellness centres in the vicinity. These establishments offer a range of treatments, from massages to facials, providing a great way to unwind and rejuvenate during your stay. ### How can I save on a luxury hotel in La Mesa with Expedia? ### Is it cheaper to book a luxury La Mesa hotel and flights as a package? ### Can I cancel my luxury hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Oceanfront-Hotels.0-0-d6068523-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - 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