Title: Book the Best La Mesa LUXURY Hotels - Upscale Hotels in La Mesa, CA | Expedia.ca [Hotels in La Mesa](https://expedia.ca/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Vacation Rentals in La Mesa](https://expedia.ca/La-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals)[Flights to La Mesa](https://expedia.ca/Cheap-Flights-To-La-Mesa.d8484.Travel-Guide-Flights)[La Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesa.d8484.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.ca/La-Mesa.d8484.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/4f7cd2ecead0197821ab65005d48bfd4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michele Butts # Find luxury hotels in La Mesa, CA ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on La Mesa Luxury Hotels Tonight [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-09-26&endDate=2025-09-27&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-09-27&endDate=2025-09-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-09-26&endDate=2025-09-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top La Mesa Luxury Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/aa7dcb3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/bb4bfc7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/965cd455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/a7e21110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus La Mesa San Diego La Mesa 8.2/10 Very good (1024) "Excelent place to stay." CA $138 CA $152 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/La-Mesa-Hotels-Best-Western-Plus-La-Mesa-San-Diego.h20454.Hotel-Information) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/92dc58f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/4d8ee2eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/2565e8b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/4c5e2949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 La Mesa, CA La Mesa 7.2/10 Good (1002) "Nice place" CA $124 CA $137 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/La-Mesa-Hotels-Motel-6-La-Mesa.h565024.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/a9306a72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/879bd035.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/76a4108b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/511470e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn La Mesa La Mesa 6.8/10 (1103) "Great motel for family vacations" CA $89 CA $98 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/La-Mesa-Hotels-Heritage-Inn-La-Mesa.h2811010.Hotel-Information) ![Suite, Multiple Beds, Kitchenette](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/2f1c0503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/f398a60c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/53e8bbfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/d356b4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express La Mesa Near SDSU by IHG La Mesa 8.2/10 Very good (405) "Was a 10/10, great place to stay " CA $155 CA $171 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/La-Mesa-Hotels-Holiday-Inn-La-Mesa.h26924.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11®ionId=8484&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top La Mesa Hotel Reviews ![Best Western Inn & Suites San Diego – Zoo/SeaWorld Area ](//images.trvl-media.com/lodging/1000000/50000/40800/40745/a5f33771_y.jpg) ### Best Western Inn & Suites San Diego – Zoo/SeaWorld Area 10/10 Excellent "friendly and helpful staff" [](https://expedia.ca/San-Diego-Hotels-Comfort-Inn-Suites-San-Diego-Zoo-SeaWorld-Area.h40745.Hotel-Information) ![Bay Club Hotel & Marina](//images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Great calm place" [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Room was great! Tile in bathroom was dirty. Sink did not function, front desk was notified. Otherwise a great stay, I'll be back" [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Brilliant Atmosphere, all perfect." [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Handlery Hotel](//images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "The hotel was very nice, if a little dated, with a really nice pool area! It felt safe and I slept well here! The air conditioner was quiet which is a bonus in any hotel!" [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Perfect stay" [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Great " [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](//images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Loved area convenient and very safe! " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![California Suites Hotel](//images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a_y.jpg) ### California Suites Hotel 10/10 Excellent "Location and friendly people " [](https://expedia.ca/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury holiday in La Mesa? > Use Expedia and let us help you arrange a flight to San Diego, CA (SEE-Gillespie Field) airport or San Diego, CA (MYF-Montgomery Field) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that La Mesa has to offer. During your visit, you might want to enjoy the entertainment which La Mesa is known for. ### When can I expect good weather in La Mesa? > Planning for the weather is an important factor for making your trip to La Mesa a success, especially when you're splurging. The hottest months are usually August and September with an average temp of 72°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for La Mesa is 12 inches. ### What's there to see and do in La Mesa? > Enjoy La Mesa with a stop at Mount Helix Park, San Diego Zoo, and Mission Bay. If you have a bit of extra time while you're in the area, you might want to check out Petco Park and Port of San Diego. ### How can I get around La Mesa? > It's easier to get around town in style when you know your options. 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[Hotels with Kitchenettes in San Carlos](https://www.expedia.ca/San-Carlos-San-Diego-Hotels-Hotels-With-Kitchenettes.0-n553248635976468591-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in San Carlos](https://www.expedia.ca/San-Carlos-San-Diego-Hotels-Oceanfront-Hotels.0-n553248635976468591-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in San Carlos](https://www.expedia.ca/San-Carlos-San-Diego-Hotels-Pet-Friendly-Hotel.0-n553248635976468591-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Scuba Diving Hotels in San Carlos](https://www.expedia.ca/San-Carlos-San-Diego-Hotels-Scuba-Diving-Vacations.0-n553248635976468591-0-tscubadivingvacations.Travel-Guide-Filter-Hotels) - [Cheap Hotels in San Diego Coast](https://www.expedia.ca/San-Diego-Coast-Hotels-Cheap-Hotels.0-0-d553248633966884021-tCheapHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in San Diego Coast](https://www.expedia.ca/San-Diego-Coast-Hotels-Family-Hotel.0-0-d553248633966884021-tFamilyHotel.Travel-Guide-Filter-Hotels) - 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[Hotel Wedding Venues Hotels in San Diego](https://www.expedia.ca/San-Diego-Hotels-Wedding-Hotels.0-0-d3073-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Spring Valley](https://www.expedia.ca/Spring-Valley-Hotels-Cheap-Hotels.0-0-d177858-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Spring Valley](https://www.expedia.ca/Spring-Valley-Hotels-Golf-Hotel.0-0-d177858-tGolfHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Spring Valley](https://www.expedia.ca/Spring-Valley-Hotels-Ski-Hotel.0-0-d177858-tSkiHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Spring Valley](https://www.expedia.ca/Spring-Valley-Hotels-Spa-Hotel.0-0-d177858-tSpaHotel.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Windsor Hills](https://www.expedia.ca/Windsor-Hills-La-Mesa-Hotels-Adults-Only-Resorts.0-n553248635976482085-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Golf Hotels in Windsor Hills](https://www.expedia.ca/Windsor-Hills-La-Mesa-Hotels-Golf-Hotel.0-n553248635976482085-0-tGolfHotel.Travel-Guide-Filter-Hotels) - 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