Title: Book the Best La Mesa LUXURY Hotels - Upscale Hotels in La Mesa, CA | Expedia.ca [Hotels in La Mesa](https://expedia.ca/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Vacation Rentals in La Mesa](https://expedia.ca/La-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals)[Flights to La Mesa](https://expedia.ca/Cheap-Flights-To-La-Mesa.d8484.Travel-Guide-Flights)[La Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesa.d8484.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.ca/La-Mesa.d8484.Destination-Travel-Guides) ![View from Mount Helix, in La Mesa, near San Diego, California](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in La Mesa, CA - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on La Mesa Luxury Hotels Tonight [Jan 2 - Jan 3](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-01-02&endDate=2026-01-03&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Jan 3 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-01-03&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for La Mesa luxury hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/aa7dcb3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/965cd455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/bb4bfc7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/a7e21110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus La Mesa San Diego [](https://www.expedia.ca/La-Mesa-Hotels-Best-Western-Plus-La-Mesa-San-Diego.h20454.Hotel-Information) La Mesa 8.4/10 Very good (1000) "Nice clean place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawn CA $156 CA $172 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/La-Mesa-Hotels-Best-Western-Plus-La-Mesa-San-Diego.h20454.Hotel-Information) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/92dc58f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/2565e8b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/46653e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/565100/565024/4c5e2949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 La Mesa, CA [](https://www.expedia.ca/La-Mesa-Hotels-Motel-6-La-Mesa.h565024.Hotel-Information) La Mesa 7.2/10 Good (1001) "Place was decent a bit dusty in the room and the parking was very very tight but for a quick stay it was fine!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor [](https://www.expedia.ca/La-Mesa-Hotels-Motel-6-La-Mesa.h565024.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/a9306a72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/76a4108b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/511470e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/9bbd9040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn La Mesa [](https://www.expedia.ca/La-Mesa-Hotels-Heritage-Inn-La-Mesa.h2811010.Hotel-Information) La Mesa 7.0/10 Good (1221) "room was clean and staff very friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $74 CA $81 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/La-Mesa-Hotels-Heritage-Inn-La-Mesa.h2811010.Hotel-Information) ![Suite, Multiple Beds, Kitchenette](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/2f1c0503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/3d92e71b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/53e8bbfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/27000/26924/0ae9a107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express La Mesa Near SDSU by IHG [](https://www.expedia.ca/La-Mesa-Hotels-Holiday-Inn-La-Mesa.h26924.Hotel-Information) La Mesa 8.2/10 Very good (459) "Great Stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jazmin CA $262 CA $289 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/La-Mesa-Hotels-Holiday-Inn-La-Mesa.h26924.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-16&endDate=2026-01-17®ionId=8484&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top La Mesa Hotel Reviews ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Work place, meetin place, seimming pool, convenience shop, delicious and high quality breakfasts, Keeping all places very neat and clean. " [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "The big surprise is the Saturday farmers market right around the corner—such a great location!" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](https://images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Our night stay was excellent. Room was clean and nice. Marcel in reception was wonderful and professional. " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![San Diego Mission Bay Resort](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/bbcdbd6d_y.jpg) ### San Diego Mission Bay Resort 10/10 Excellent "We love this property!! This was our 2nd time staying. We booked for NYE, which although it was raining, we were still able to enjoy the jacuzzi. Check in was smooth, and you can’t beat the location. Still close to the liveliness of downtown, and old town, but quiet enough for a nice getaway. The bay view is gorgeous, and the christmas tree light up from Seaworld was a nice surprise. Definitely recommend this property. The only downfall being the $45/ night parking. We will be back in the summer for full usage! " [](https://expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Hotel was renovated and well kept… staff were excellent!" [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "The atmosphere was excellent! Right next to the marina and the on site restaurant was soooo good" [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Easy check in rooms are great and clean" [](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![Pendry San Diego](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "You drive to the front of the hotel and you are metnI" [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Room and bathroom were very clean. The bathtub was a little shallow and was hard to take a bath in. " [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ## Frequently asked questions ### Which area of La Mesa is best to stay in for luxury hotels? > This neighbourhood is the historic heart of La Mesa, known for its pedestrian-friendly layout and a collection of independent shops, restaurants, and cafes. You'll find a relaxed, small-town atmosphere here, with events like the weekly farmers' market adding to its local appeal. The area is easily walkable, making it convenient to explore on foot. > > > Couples looking for a refined getaway will appreciate this location. The boutique hotels and upscale dining options in La Mesa Village offer a more intimate and personalised experience compared to larger, more generic hotels. You can enjoy strolls along La Mesa Boulevard, discover unique local businesses, and relax in a setting that feels distinctly Californian. > > > For solo travellers who appreciate quality and convenience, staying in or near La Mesa Village is also an excellent option. The area provides easy access to public transport, including the trolley, making it simple to explore wider San Diego without needing a car. ### How much does a luxury hotel in La Mesa cost? ### What luxury activities and experiences are there in La Mesa? > This area is generally quiet and well-maintained, providing a comfortable base for visitors. You'll find a selection of upscale hotels that often feature amenities like high-end fitness equipment and pools. The Grossmont Centre itself is a large outdoor shopping centre with a variety of well-known retailers and dining establishments, great for those who enjoy a bit of retail therapy or a nice meal out. > > > Couples looking for a refined getaway will appreciate the proximity to several excellent golf courses, such as the Cottonwood Golf Club, which offers a picturesque setting for a round of golf. After a day on the greens, you can enjoy a gourmet meal at one of the upscale restaurants within easy reach, many of which focus on fresh, local ingredients. > > > Those seeking wellness and relaxation will find several high-quality spas and wellness centres in the vicinity. These establishments offer a range of treatments, from massages to facials, providing a great way to unwind and rejuvenate during your stay. ### How can I save on a luxury hotel in La Mesa with Expedia? ### Is it cheaper to book a luxury La Mesa hotel and flights as a package? ### Can I cancel my luxury hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Oceanfront-Hotels.0-0-d6068523-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - 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