Title: Book the Best La Mesa CASINO Hotels & Resorts in 2025 | Expedia.ca [Hotels in La Mesa](https://expedia.ca/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Vacation Rentals in La Mesa](https://expedia.ca/La-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals)[Flights to La Mesa](https://expedia.ca/Cheap-Flights-To-La-Mesa.d8484.Travel-Guide-Flights)[La Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesa.d8484.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.ca/La-Mesa.d8484.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/4f7cd2ecead0197821ab65005d48bfd4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michele Butts # Find Casino Hotels in La Mesa, CA from CA $101 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on La Mesa Casino Hotels Tonight [Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-10-22&endDate=2025-10-23&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-10-23&endDate=2025-10-24&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top La Mesa Casino Hotels ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115550000/115546100/115546052/23c0cc46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, books, music library](https://images.trvl-media.com/lodging/116000000/115550000/115546100/115546052/cf07edcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/116000000/115550000/115546100/115546052/0b13c12d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115550000/115546100/115546052/8d693e0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4BR/3Bth King Bed, Big Yard, Prime Area, Ranch La Mesa 8.0/10 Very good (1) "Check-in was easy. The neighborhood felt very safe and was quiet. Every type of shopping is nearby; from groceries to shoes. Local restaurants are abundant! LaMesa Bistro and Centifontis serve delicious food. The unit is spacious, especially the kitchen. There is A/C in each bedroom and the living room. Teenagers enjoyed playing the PS4 that is in the bedroom with the high windows where the picture shows a desk. We enjoyed our coffee early in the morning beneath the balcony of the upstairs... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen Z. CA $97 CA $515 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/La-Mesa-Hotels-Spacious-4-BR-Home-W-King-Bed.h115546052.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34150000/34142000/34141960/148582f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34150000/34142000/34141960/96caf016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34150000/34142000/34141960/e96e5cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34150000/34142000/34141960/2473bb3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful NEW One Bedroom Studio in San Diego (Mt. Helix) Mount Helix 10/10 Exceptional (4) "Cindy was and amazing host and answer my questions promptly. The studio is well equipped for quick meals and the bathroom is upscale. All the appointments and finishes are as advertised and would stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen M. CA $188 CA $332 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/La-Mesa-Hotels-Beautiful-NEW-One-Bedroom-Studio-In-San-Diego.h34141960.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/116000000/115730000/115725000/115724997/0f5f234d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115730000/115725000/115724997/4bfc31f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115730000/115725000/115724997/a52671a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/116000000/115730000/115725000/115724997/b4696894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 4BR/2BTH King Bed Ranch Style, Prime Area La Mesa CA $97 CA $516 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/La-Mesa-Hotels-Spacious-4-BR-Home.h115724997.Hotel-Information) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/1f4c359a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8995625e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/91cdc1c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sycuan Casino Resort El Cajon 9.2/10 Wonderful (1582) "Great resort!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicky CA $126 CA $156 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/a653b43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/63e66623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/4e3a5f44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/6af9aa5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 El Cajon, CA - San Diego El Cajon 7.2/10 Good (1424) "Great rooms for price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerod CA $92 CA $101 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/El-Cajon-Hotels-Motel-6-El-Cajon.h996144.Hotel-Information) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/43ae1d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/05adb83a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/d3cdb295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/6248eb98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Mission Valley/Hotel Circle Mission Valley 8.4/10 Very good (1385) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ariel CA $156 CA $179 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Mission-ValleyHotel-Circle.h1987617.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/089f0b78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/315ec7ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/cb94470d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/8aabd9fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ayres Lodge Alpine Alpine 9.2/10 Wonderful (1036) "Awesome place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kyle CA $147 CA $159 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Alpine-Hotels-Ayres-Lodge-Alpine.h50032.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/w3836h2556x3y3-467b2b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/e9cd53ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/w3839h2555x0y3-5f9fe6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/720d452f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Imperial Beach San Diego Imperial Beach 9.4/10 Exceptional (911) "Really nice place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joe CA $177 CA $202 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Imperial-Beach-Hotels-Hampton-Inn-Suites-Imperial-Beach-San-Diego.h49284697.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/91baa1e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/8bb8fc35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/a5cb77af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Marina Gateway Hotel National City 9.2/10 Wonderful (3319) "Nice place to stay !" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Soundararaj CA $175 CA $193 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/a90f2d6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/14f93e35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/d8ecd896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/18bcfb40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Suites San Ysidro, CA -San Diego South Bay San Ysidro 7.8/10 Good (1312) "Ideally located " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony CA $98 CA $112 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/San-Ysidro-Hotels-Studio-6-Suites-San-Ysidro.h1798071.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-05&endDate=2025-11-06®ionId=8484&adults=2&amenities=CASINO&sort=RECOMMENDED&openPlayBack=true) ## Top La Mesa Hotel Reviews ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "Great location. Very central. Did not love how you can hear everything outside your room " [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ## Frequently asked questions ### Searching for casino hotels in La Mesa? > Headed to La Mesa for some gaming? You're in luck, because you'll find Jamul Casino, Sycuan Casino, and Barona Casino in the area, as well as a lot more to see and do. Tourists speak highly of the family-friendly activities and local cuisine. You might want to visit popular sights in the larger area including San Diego Zoo, Mission Bay, and Petco Park. ### How many hotels that are good for gaming should I expect to find in La Mesa? > Luck be your lady at one of Expedia's 159 lodging options close to the casinos in La Mesa. ### When should I take my casino trip to La Mesa? > You might spend a lot of your vacation inside, but if you want to see more of the area, looking at local weather trends is a good idea. The hottest months are usually August and September with an average temp of 72°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for La Mesa is 12 inches. ### What is there to do in La Mesa? > You can head to Fashion Valley Mall, Seaport Village, or Chula Vista Center to shop for the perfect souvenir. La Mesa is known for its entertainment venues, and you can check out cultural spots such as USS Midway Museum, Cal Coast Credit Union Open Air Theater, and San Diego Natural History Museum. In addition, you might want to add Mount Helix Park and Computer Museum of America to your list. ### What are my transportation options for my casino getaway to La Mesa? > Here are some transportation options in La Mesa: You can arrange a flight to the nearest airport, which is San Diego, CA (SEE-Gillespie Field), located 4.9 mi (7.8 km) from the city center. 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