Search Apart Hotels in La Mesa

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Our top choices for La Mesa aparthotels

1. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (244 reviews)
"Excellent location, near little Italy, zoo and airport. Be aware that you are near airport so expect more noise than normal"
United States
Willie
The price is CA $165
CA $234 total
includes taxes & fees
Dec 2 - Dec 3
City24 Hotel Little Italy Mission Hills

2. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,265 reviews)
"Amazing stay! Would definitely come back!"
United States
Dirosia
The price is CA $204
CA $237 total
includes taxes & fees
Dec 6 - Dec 7
Marriott Vacation Club®, San Diego

3. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (522 reviews)
"Front desk service was amazing and love the central location to all the LGBTQ bars and restaurants."
United States
Victor
The price is CA $128
CA $144 total
includes taxes & fees
Nov 19 - Nov 20
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

4. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (414 reviews)
"clean, affordable, safe, such a great stay!"
United States
Beatriz
The price is CA $139
CA $161 total
includes taxes & fees
Nov 17 - Nov 18
Little Italy Inn - Limited Service Apart Hotel

5. Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (242 reviews)
"Wonderful place!"
Canada
Eric
The price is CA $139
CA $158 total
includes taxes & fees
Nov 17 - Nov 18
Kasa Gaslamp Quarter San Diego

6. The Penn Hotel - Walk to Attractions & Sleeps 5!!

The Penn Hotel - Walk to Attractions & Sleeps 5!!
Downtown San Diego
The price is CA $98
CA $465 total
includes taxes & fees
Nov 17 - Nov 18
The Penn Hotel - Walk to Attractions & Sleeps 5!!

7. The Penn Hotel - Designer 2BR Near Gaslamp & Park

The Penn Hotel - Designer 2BR Near Gaslamp & Park
Downtown San Diego
The price is CA $98
CA $465 total
includes taxes & fees
Nov 17 - Nov 18
The Penn Hotel - Designer 2BR Near Gaslamp & Park

8. The Penn Hotel - Smart TV, AC & Downtown Location!

The Penn Hotel - Smart TV, AC & Downtown Location!
Downtown San Diego
The price is CA $98
CA $449 total
includes taxes & fees
Nov 16 - Nov 17
The Penn Hotel - Smart TV, AC & Downtown Location!

9. The Penn Hotel - Smart TV, King Bed & Walkability!

The Penn Hotel - Smart TV, King Bed & Walkability!
Downtown San Diego
The price is CA $98
CA $449 total
includes taxes & fees
Nov 16 - Nov 17
The Penn Hotel - Smart TV, King Bed & Walkability!

10. The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!

The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!
Downtown San Diego
The price is CA $84
CA $300 total
includes taxes & fees
Nov 16 - Nov 17
The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!

11. The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!

The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!
Downtown San Diego
The price is CA $98
CA $465 total
includes taxes & fees
Nov 17 - Nov 18
The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!

12. The Penn Hotel - Smart TV, AC & Gaslamp Steps Away

The Penn Hotel - Smart TV, AC & Gaslamp Steps Away
Downtown San Diego
The price is CA $98
CA $449 total
includes taxes & fees
Nov 16 - Nov 17
The Penn Hotel - Smart TV, AC & Gaslamp Steps Away

13. The Penn Hotel - King & Queen Bed | Gaslamp Life

The Penn Hotel - King & Queen Bed | Gaslamp Life
Downtown San Diego
The price is CA $98
CA $449 total
includes taxes & fees
Nov 16 - Nov 17
The Penn Hotel - King & Queen Bed | Gaslamp Life

14. The Penn Hotel - Sleeps 5 & Nightlife Above Clubs!

The Penn Hotel - Sleeps 5 & Nightlife Above Clubs!
Downtown San Diego
The price is CA $98
CA $465 total
includes taxes & fees
Nov 17 - Nov 18
The Penn Hotel - Sleeps 5 & Nightlife Above Clubs!

15. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (564 reviews)
"Super nice amenities - would stay again. Great location"
United States
Nirmeen
The price is CA $257
CA $403 total
includes taxes & fees
Nov 16 - Nov 17
Kasa Little Italy San Diego

16. The Penn Hotel -Live Above Gaslamp Nightlife &AC

The Penn Hotel -Live Above Gaslamp Nightlife &AC
Downtown San Diego
The price is CA $98
CA $465 total
includes taxes & fees
Nov 17 - Nov 18
The Penn Hotel -Live Above Gaslamp Nightlife &AC

17. The Penn Hotel - Sleeps 5 & Gaslamp Nightlife Now!

The Penn Hotel - Sleeps 5 & Gaslamp Nightlife Now!
Downtown San Diego
The price is CA $98
CA $449 total
includes taxes & fees
Nov 16 - Nov 17
The Penn Hotel - Sleeps 5 & Gaslamp Nightlife Now!

18. The Penn Hotel - Premium Beds & Gaslamp Nightlife!

The Penn Hotel - Premium Beds & Gaslamp Nightlife!
Downtown San Diego
The price is CA $98
CA $449 total
includes taxes & fees
Nov 16 - Nov 17
The Penn Hotel - Premium Beds & Gaslamp Nightlife!

19. The Penn Hotel - Steps to Gaslamp & Petco Park, AC

The Penn Hotel - Steps to Gaslamp & Petco Park, AC
Downtown San Diego
The price is CA $98
CA $467 total
includes taxes & fees
Nov 18 - Nov 19
The Penn Hotel - Steps to Gaslamp & Petco Park, AC

20. The Penn Hotel - King Bed, AC & Gaslamp Nightlife!

The Penn Hotel - King Bed, AC & Gaslamp Nightlife!
Downtown San Diego
The price is CA $98
CA $467 total
includes taxes & fees
Nov 17 - Nov 18
The Penn Hotel - King Bed, AC & Gaslamp Nightlife!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about La Mesa

Nestled between rolling hills, this charming suburb offers hiking trails through Mission Trails Park and Lake Murray's scenic waterfront paths. Visit the vibrant farmers market on Fridays, then explore the antique shops and local breweries along La Mesa Boulevard's historic district.

A sunset over a mountainous landscape with scattered clouds.

Top reviews in La Mesa

Frequently Asked Questions

What can I expect from my La Mesa aparthotel stay?

When you choose an aparthotel or serviced apartment in La Mesa, expect to be more centrally situated. While in this family-friendly area, you can visit the shops and seek out the entertainment venues. La Mesa is also known for its restaurants and zoo.

What is the top aparthotel for my stay in La Mesa?

Located 8.5 mi (13.7 km) from La Mesa, Marriott Vacation Club®, San Diego is a favorite aparthotel featuring 264 apartments with free WiFi and comfy beds as well as hotel amenities like a restaurant. In the area, a couple of other top aparthotels to consider are Little Italy Inn - Limited Service Apart Hotel and Uptown Inn by Vantaggio - Limited Service Apart-Hotel.

How many aparthotels will I find in La Mesa?

Even though you won't find many aparthotels that are bookable on Expedia and located in La Mesa, you'll find plenty of choices with 175 lodging options. Let us help you find similar options to aparthotels such as apartments or condos.

What should I see in La Mesa?

Take time to visit top places in the surrounding region such as San Diego Zoo and Mission Bay. Explore the area and family-friendly sights such as San Diego Natural History Museum, or get out into nature at a spot like Balboa Park. While in the area, you can also visit popular places like Petco Park and Port of San Diego.

What is an aparthotel?

An aparthotel is both a hotel and an apartment, with amenities you might expect at a traditional hotel, and more space and privacy found in an apartment. Feel like a local in an apartment-like space, usually located in the heart of La Mesa. Enjoy making home-cooked meals in the full kitchen or kitchenette and having extra space to spread out while you're in town.

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