Title: Hotels by La Quinta Inn & Suites in La Jolla Mesa | Expedia.ca [La Jolla Mesa Travel Guide](https://expedia.ca/La-Jolla-La-Jolla-Mesa.dx553248635976480832)[Vacation Rentals in La Jolla](https://expedia.ca/La-Jolla-Vacation-Rentals.d6126584.Travel-Guide-VacationRentals)[Flights to La Jolla](https://expedia.ca/Cheap-Flights-To-La-Jolla.d6126584.Travel-Guide-Flights)[Things to do in La Jolla](https://expedia.ca/Things-To-Do-In-La-Jolla.d6126584.Travel-Guide-Activities)[La Jolla Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-La-Jolla-Mesa.d553248635976480832.Car-Rental-Guide)[La Jolla Mesa Vacations](https://expedia.ca/La-Jolla-Mesa.d553248635976480832.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in La Jolla Mesa ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 20 - Oct 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976480832&startDate=2025-10-20&endDate=2025-10-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 21 - Oct 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976480832&startDate=2025-10-21&endDate=2025-10-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976480832&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976480832&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top La Jolla Mesa La Quinta Inn & Suites Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Jolla-Mesa-La-Jolla-Hotels-La-Quinta-Inn-Suites.0-n553248635976480832-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Jolla-Mesa-La-Jolla-Hotels-La-Quinta-Inn-Suites.0-n553248635976480832-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top La Jolla Mesa Hotel Reviews ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Older property but great location. Friendly staff and lots nearby. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](//images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Safe" [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](//images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Amazing staff! From front desk to dinning and bar area! Safe area, walking distance to restaurants " [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "The only negative is you have to pay for parking daily $35 and a fee " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "The hotel is beautiful and conveniently located near Seaport Village, offering everything you need within walking distance. You and your family can fully enjoy your stay without having to venture far—Seaport Village and the hotel itself provide plenty to experience. The dining options are both affordable and excellent. There is truly no better hotel to choose from." [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Super easy check in process, staff was extremely hospitable. My room was comfortable as well. Great job Hilton" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "Great location. Very central. Did not love how you can hear everything outside your room " [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ![Legacy Resort Hotel & Spa](//images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4_y.jpg) ### Legacy Resort Hotel & Spa 10/10 Excellent "Quick one night stay after a day at San Diego Zoo. Room was comfortable and quiet. Restaurant on site is absolutely delicious. Self parking @ $35 per night was more reasonable than most, and parking was easy. We would absolutely stay again. " [](https://expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Comfort Inn San Diego Airport At The Harbor](//images.trvl-media.com/lodging/1000000/10000/8800/8727/17ffc972_y.jpg) ### Comfort Inn San Diego Airport At The Harbor 10/10 Excellent "Nice clean room. Everything was great. " [](https://expedia.ca/San-Diego-Hotels-Comfort-Inn-San-Diego-Airport-At-The-Harbor.h8727.Hotel-Information) ## Find out more about La Jolla Mesa ## La Jolla Mesa Hotels Guide Expedia.ca offers a selection of 9050 hotels in La Jolla Mesa. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in La Jolla Mesa. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the La Jolla Mesa neighborhood you prefer. Go ahead. 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[Hotels near Tourmaline Surfing Park](https://www.expedia.ca/Tourmaline-Surfing-Park-Hotels.0-l553248632557178851-0.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in University City](https://www.expedia.ca/University-City-San-Diego-Hotels-Wyndham-Hotels.0-n553248635976008131-0--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [Upper Hermosa Hotels](https://www.expedia.ca/Upper-Hermosa-La-Jolla-Hotels.0-n553248635976472387-0.Travel-Guide-Filter-Hotels) - [Flights to La Jolla](https://www.expedia.ca/Cheap-Flights-To-La-Jolla.d6126584.Travel-Guide-Flights) - [Flights to San Diego](https://www.expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights) - [Flights from La Jolla](https://www.expedia.ca/lp/flights/6126584/flights-from-la-jolla) - [Flights from Vancouver (YVR) to San Diego (SAN)](https://www.expedia.ca/lp/flights/yvr/san/vancouver-to-san-diego) - [Flights from Toronto (YYZ) to San Diego (SAN)](https://www.expedia.ca/lp/flights/yyz/san/toronto-to-san-diego) - [Visit Bird Rock](https://www.expedia.ca/La-Jolla-Bird-Rock.dx641199223868248064) - [Visit Muirlands](https://www.expedia.ca/La-Jolla-Muirlands.dx553248635976482382) - [La Jolla Vacations](https://www.expedia.ca/La-Jolla.d6126584.Destination-Travel-Guides) - [Visit La Jolla](https://www.expedia.ca/La-Jolla.dx6126584) - [Tourmaline Surfing Park](https://www.expedia.ca/Tourmaline-Surfing-Park-Pacific-Beach.d553248632557178851.Vacation-Attraction) - [Car rental La Jolla](https://www.expedia.ca/Car-Rentals-In-La-Jolla.d6126584.Car-Rental-Guide) - [Hertz Rental Cars in La Jolla](https://www.expedia.ca/Hertz-Car-Rentals-In-La-Jolla.d6126584-c40.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in La Jolla](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-La-Jolla.d6126584-c45.Car-Rental-Guide-Suppliers) - [La Jolla Vacation Rentals](https://www.expedia.ca/La-Jolla-Vacation-Rentals.d6126584.Travel-Guide-VacationRentals) - [Things to do in La Jolla](https://www.expedia.ca/Things-To-Do-In-La-Jolla.d6126584.Travel-Guide-Activities) - [Book Hotels in La Jolla Mesa on Expedia.com](https://www.expedia.com/La-Jolla-Mesa-La-Jolla-Hotels-La-Quinta-Inn-Suites.0-n553248635976480832-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)