Title: Book the Best Knoxville SPA Resorts from CA $294 - Spa Hotels in Knoxville, MD | Expedia.ca [Hotels in Knoxville](https://expedia.ca/Knoxville-Hotels.d6277693.Travel-Guide-Hotels)[Vacation Rentals in Knoxville](https://expedia.ca/Knoxville-Vacation-Rentals.d6277693.Travel-Guide-VacationRentals)[Knoxville Car Rentals](https://expedia.ca/Car-Rentals-In-Knoxville.d6277693.Car-Rental-Guide)[Knoxville Vacation Packages](https://expedia.ca/Knoxville.d6277693.Destination-Travel-Guides) ![Maryland Heights Trail at Harper's Ferry, just before sunset! #TakeAHike](https://images.trvl-media.com/place/6277693/4830d164-9c28-4908-9d44-a2d97a8dd30b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ricky Wolfe # Find Spa Hotels in Knoxville, MD from CA $294 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Knoxville Spa Hotels Tonight [Nov 8 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6277693&startDate=2025-11-08&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 9 - Nov 10](https://www.expedia.ca/Hotel-Search?regionId=6277693&startDate=2025-11-09&endDate=2025-11-10&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6277693&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6277693&startDate=2025-11-21&endDate=2025-11-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Knoxville Spa Hotels ![Couples treatment rooms](https://images.trvl-media.com/lodging/4000000/3090000/3082200/3082115/b5a24271.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/4000000/3090000/3082200/3082115/f8c19c35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3090000/3082200/3082115/46449a17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/4000000/3090000/3082200/3082115/9aa4d92c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hillbrook Inn Charles Town 8.6/10 Excellent (670) "We had an amazing day at the Hillbrook Inn. I recommend this to anybody who would like a quiet serene stay. Staff is wonderful and the food is amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karley CA $231 CA $294 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Martinsburg-Hotels-Hillbrook-Inn.h3082115.Hotel-Information) ![Deep-tissue massages, Swedish massages, prenatal massages](https://images.trvl-media.com/lodging/115000000/114280000/114275900/114275854/c155be43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/115000000/114280000/114275900/114275854/9a999e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114280000/114275900/114275854/2337af83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City shuttle](https://images.trvl-media.com/lodging/115000000/114280000/114275900/114275854/8eb9ca38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Burg Leesburg's Old and Historic District 9.8/10 Exceptional (32) "Every detail of this place was so carefully curated. The design, the food, and the staff were all exceptional. The beds were so comfortable and the service was straight forward and accommodating. We thoroughly enjoyed our stay and would come back again and again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristina CA $392 CA $451 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Leesburg-Hotels-Hotel-Burg.h114275854.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/17000000/16290000/16281800/16281705/3fe7c40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16290000/16281800/16281705/ef0db233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/17000000/16290000/16281800/16281705/8f141c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, 1 King Bed, Hot Tub, Mountain View](https://images.trvl-media.com/lodging/17000000/16290000/16281800/16281705/846a016e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stone Manor Boutique Inn Lovettsville 9.6/10 Exceptional (95) "The experience was very good, will return in the future. The breakfast was excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marvin CA $305 CA $348 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Lovettsville-Hotels-Stone-Manor-Boutique-Inn.h16281705.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-22&endDate=2025-11-23®ionId=6277693&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Knoxville Hotel Reviews ![Hilton Garden Inn Frederick](//images.trvl-media.com/lodging/2000000/1610000/1608200/1608110/6052ee0f_y.jpg) ### Hilton Garden Inn Frederick 10/10 Excellent "The staff onsite was amazing, friendly and check-in was quick. I will being staying here every time I am in the area. " [](https://expedia.ca/Frederick-Hotels-Hilton-Garden-Inn-Frederick.h1608110.Hotel-Information) ![Clarion Inn Harpers Ferry - Charles Town](//images.trvl-media.com/lodging/1000000/980000/977400/977326/a9078e90_y.jpg) ### Clarion Inn Harpers Ferry - Charles Town 10/10 Excellent "Very nice room / staff Would recommend " [](https://expedia.ca/Martinsburg-Hotels-Clarion-Inn-Harpers-Ferry-Charles-Town.h977326.Hotel-Information) ![Lansdowne Resort and Spa](//images.trvl-media.com/lodging/1000000/30000/27700/27700/5ae32850_y.jpg) ### Lansdowne Resort and Spa 10/10 Excellent "Appreciated the upgrade! Thank you" [](https://expedia.ca/Leesburg-Hotels-Lansdowne-Resort-And-Spa.h27700.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Knoxville? > Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Check out the riverfront in Knoxville - worth a picture or two! Be sure to enjoy activities like rafting and innertubing during your stay. Spa hotels are the perfect way to break out of your routine and add a layer of luxury to your weekend away. ### What's there to see and do in Knoxville? > Take in the sights and attractions that Knoxville offers with a visit to Maryland Heights, Lockhouse 33, and South Mountain State Park. If you have a little extra time during your trip, you might want to make a stop at Chesapeake and Ohio Canal and Shenandoah River. ### What is a Knoxville spa hotel? > Spa hotels in Knoxville have on-site spas which offer services like couples massages and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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