Title: Book the Best BUSINESS Hotels in Knoxville in 2025 | Expedia.ca [Hotels in Knoxville](https://expedia.ca/Knoxville-Hotels.d6277693.Travel-Guide-Hotels)[Vacation Rentals in Knoxville](https://expedia.ca/Knoxville-Vacation-Rentals.d6277693.Travel-Guide-VacationRentals)[Knoxville Car Rentals](https://expedia.ca/Car-Rentals-In-Knoxville.d6277693.Car-Rental-Guide)[Knoxville Vacation Packages](https://expedia.ca/Knoxville.d6277693.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/f9f0e4f934227bfdb72378637c2ec3dc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Kayla Berry # Find Business Hotels in Knoxville, MD from CA $99 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Knoxville Business Hotels Tonight [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=6277693&startDate=2025-11-03&endDate=2025-11-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=6277693&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6277693&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6277693&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Knoxville Business Hotels ![Exterior](https://images.trvl-media.com/lodging/43000000/42670000/42662200/42662191/74ff1b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/43000000/42670000/42662200/42662191/919ca91c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible Bathtub (Communications)](https://images.trvl-media.com/lodging/43000000/42670000/42662200/42662191/6968ff7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/43000000/42670000/42662200/42662191/dc22cd77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Brunswick - Harpers Ferry Area by IHG Knoxville 9.6/10 Exceptional (431) "Clean, friendly ppl, good breakfast, updated furnishings " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly CA $154 CA $171 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Frederick-Hotels-Holiday-Inn-Express-Suites-Brunswick.h42662191.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6390000/6382400/6382320/e0190150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6390000/6382400/6382320/0b49c83a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/7000000/6390000/6382400/6382320/0be861ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast meal](https://images.trvl-media.com/lodging/7000000/6390000/6382400/6382320/00b668ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hillside Hotel Knoxville 6.8/10 (425) "The view was spectacular and I was fortunate enough to hear (not seeing) a fireworks event that echoed through the mountains! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Colleen CA $88 CA $99 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Frederick-Hotels-The-Hillside-Hotel.h6382320.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/980000/977400/977326/a9078e90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/977400/977326/1054ff00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977400/977326/627db10f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/980000/977400/977326/cba53522.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarion Inn Harpers Ferry - Charles Town Harpers Ferry 8.0/10 Very good (1045) "Great staff. Great location. Great restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) bradley CA $125 CA $140 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Martinsburg-Hotels-Clarion-Inn-Harpers-Ferry-Charles-Town.h977326.Hotel-Information) ![Suite, 1 King Bed, Non Smoking (One Bedroom)](https://images.trvl-media.com/lodging/1000000/870000/869500/869428/ab49ac99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/870000/869500/869428/8f1da536.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/870000/869500/869428/2b7dc6b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/869500/869428/31798fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Hagerstown/Halfway Area Hagerstown 8.6/10 Excellent (1028) "Was nice for what we were expecting and the free breakfast was pretty good too!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Geoffrey T CA $92 CA $103 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Hagerstown-Hotels-Super-8-By-Wyndham-HagerstownHalfway-Area.h869428.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/60000/59600/59588/6e927b9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/60000/59600/59588/064b0256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/59600/59588/3857d565.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/60000/59600/59588/b865fb46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Frederick, MD Frederick 8.2/10 Very good (1190) "Very close to downtown and restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara CA $110 CA $122 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Frederick-Hotels-Country-Inn-Suites-By-Radisson.h59588.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25179/e301290f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25200/25179/a2deb58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/25200/25179/79116ae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/25200/25179/2b57389c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Harpers Ferry 8.6/10 Excellent (1006) "Nice location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Regina CA $117 CA $131 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Martinsburg-Hotels-Quality-Inn.h25179.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1610000/1608200/1608110/6052ee0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1610000/1608200/1608110/6e2ddf4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1610000/1608200/1608110/b4d3adf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1610000/1608200/1608110/5ff697f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Frederick Frederick 8.8/10 Excellent (1008) "Parking was good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara CA $123 CA $137 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Frederick-Hotels-Hilton-Garden-Inn-Frederick.h1608110.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/16000000/15570000/15569300/15569217/4c240ea0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast (USD 10.95 per person)](https://images.trvl-media.com/lodging/16000000/15570000/15569300/15569217/094f5e6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15570000/15569300/15569217/dea03957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/16000000/15570000/15569300/15569217/cca0563f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Martinsburg Martinsburg 9.2/10 Wonderful (734) "Great place. Always clean and staff is great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alan CA $134 CA $150 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Martinsburg-Hotels-Hilton-Garden-Inn-Martinsburg.h15569217.Hotel-Information) ![In-room safe, desk, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/20000/13000/12946/5af4bff3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/20000/13000/12946/98b410d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13000/12946/3ccaccc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13000/12946/30a5e786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Frederick Frederick 7.2/10 Good (1008) "Excellent place to stay. Far enough from the interstate to be very quiet. Easy access." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $90 CA $99 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Frederick-Hotels-Days-Inn-By-Wyndham-Frederick.h12946.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/70000/63100/63064/835cd022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/70000/63100/63064/e6df8eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/63100/63064/878c91bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/70000/63100/63064/84e63605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Martinsburg Martinsburg 8.6/10 Excellent (943) "Very clean and smelled great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane CA $125 CA $141 total includes taxes & fees Nov 28 - Nov 29 [](https://www.expedia.ca/Martinsburg-Hotels-Hampton-Inn-Martinsburg.h63064.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18®ionId=6277693&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Knoxville Hotel Reviews ![Country Inn & Suites by Radisson, Frederick, MD](//images.trvl-media.com/lodging/1000000/60000/59600/59588/6e927b9b_y.jpg) ### Country Inn & Suites by Radisson, Frederick, MD 10/10 Excellent "Great overnight stay" [](https://expedia.ca/Frederick-Hotels-Country-Inn-Suites-By-Radisson.h59588.Hotel-Information) ![Clarion Inn Harpers Ferry - Charles Town](//images.trvl-media.com/lodging/1000000/980000/977400/977326/a9078e90_y.jpg) ### Clarion Inn Harpers Ferry - Charles Town 10/10 Excellent "Clean room and staff is ready to help" [](https://expedia.ca/Martinsburg-Hotels-Clarion-Inn-Harpers-Ferry-Charles-Town.h977326.Hotel-Information) ![Lansdowne Resort and Spa](//images.trvl-media.com/lodging/1000000/30000/27700/27700/5ae32850_y.jpg) ### Lansdowne Resort and Spa 10/10 Excellent "Appreciated the upgrade! Thank you" [](https://expedia.ca/Leesburg-Hotels-Lansdowne-Resort-And-Spa.h27700.Hotel-Information) ![Days Inn by Wyndham Frederick](//images.trvl-media.com/lodging/1000000/20000/13000/12946/5af4bff3_y.jpg) ### Days Inn by Wyndham Frederick 10/10 Excellent "It was quite and comfortable easy in and out." [](https://expedia.ca/Frederick-Hotels-Days-Inn-By-Wyndham-Frederick.h12946.Hotel-Information) ![Hilton Garden Inn Martinsburg](//images.trvl-media.com/lodging/16000000/15570000/15569300/15569217/4c240ea0_y.jpg) ### Hilton Garden Inn Martinsburg 10/10 Excellent "Great place. Always clean and staff is great " [](https://expedia.ca/Martinsburg-Hotels-Hilton-Garden-Inn-Martinsburg.h15569217.Hotel-Information) ![Holiday Inn Express Charles Town by IHG](//images.trvl-media.com/lodging/2000000/1560000/1554900/1554858/89e72fbd_y.jpg) ### Holiday Inn Express Charles Town by IHG 10/10 Excellent "Eggs, sausage, potatoes " [](https://expedia.ca/Martinsburg-Hotels-Holiday-Inn-Express-Charles-Town.h1554858.Hotel-Information) ![Hilton Garden Inn Frederick](//images.trvl-media.com/lodging/2000000/1610000/1608200/1608110/6052ee0f_y.jpg) ### Hilton Garden Inn Frederick 10/10 Excellent "Very clean all around room, lobby and grounds. Easy access to interstate. " [](https://expedia.ca/Frederick-Hotels-Hilton-Garden-Inn-Frederick.h1608110.Hotel-Information) ![Red Roof Inn Leesburg, VA](//images.trvl-media.com/lodging/1000000/20000/17600/17577/610f0a4e_y.jpg) ### Red Roof Inn Leesburg, VA 10/10 Excellent "We really enjoyed our stay. I have nothing negative to say. :-)" [](https://expedia.ca/Leesburg-Hotels-Red-Roof-Inn-Leesburg.h17577.Hotel-Information) ![Hampton Inn Martinsburg](//images.trvl-media.com/lodging/1000000/70000/63100/63064/835cd022_y.jpg) ### Hampton Inn Martinsburg 10/10 Excellent "Very clean and smelled great! " [](https://expedia.ca/Martinsburg-Hotels-Hampton-Inn-Martinsburg.h63064.Hotel-Information) ## Frequently asked questions ### How much does a business hotel in Knoxville cost? > Take advantage of staying in a business hotel in Knoxville, with plenty of hotels from CA $99 offering top amenities. If you're leaning toward a little luxury, prices can rise, and vary here depending on the location, season, and hotel amenities. ### Which Knoxville hotels have fast Wi-Fi and reliable internet access? > [The Hillside Hotel](https://www.expedia.ca/Frederick-Hotels-The-Hillside-Hotel.h6382320.Hotel-Information) in Knoxville is an excellent choice for business travellers seeking fast Wi-Fi and reliable internet access. This hotel offers high-speed internet and wired connections, ensuring you can stay connected for all your work needs. > > > > Guests appreciate the friendly staff, who are always ready to assist, making your stay both comfortable and productive. The hotel also features inviting amenities such as mountain views, free toiletries, and convenient self-parking, alongside balconies or patios for a bit of relaxation after a busy day. ### Which area of Knoxville is best to stay in for business? > Knoxville, Maryland, is an ideal location for business travellers seeking a balance of convenience and a serene environment. Nestled along the scenic banks of the Potomac River, this small town offers easy access to major highways, making it a practical base for those needing to commute to nearby cities like Frederick and Washington, D.C. The area features comfortable hotels equipped with business amenities, ensuring you can work efficiently while enjoying a peaceful atmosphere. > > > > For professionals attending conferences or meetings, the proximity to the Harpers Ferry National Historical Park is a bonus. This stunning park not only provides a backdrop for relaxation after a long day but also offers opportunities for team-building activities such as hiking and kayaking. The local dining scene, with its charming restaurants and cafes, is great for informal meetings or unwinding with colleagues. > > > > If you're travelling with family while on a business trip, Knoxville's welcoming vibe makes it easy to enjoy quality time together. Explore the nearby historical sites or take a leisurely stroll along the river, creating a great balance between work and leisure. ### What business amenities should I look for in a hotel in Knoxville? > When choosing a hotel for business travel in Knoxville, it's important to find one that supports both productivity and comfort. Having reliable, high-speed Wi-Fi and a comfortable workspace in your room can make it much easier to stay focused and connected. Many hotels also offer business centres and meeting rooms, which are perfect for networking and hosting meetings. 24/7 front desk service and security provide added convenience and peace of mind, while amenities like an on-site fitness centre, dining options, and laundry services help balance work with relaxation. Additionally, easy access to public transportation or on-site parking ensures a smooth, hassle-free experience. ### How can I save on a business hotel in Knoxville with Expedia? > [One Key™](https://www.expedia.ca/welcome-one-key) members always get our best prices. Find our best Knoxville business hotel deals by joining Expedia's free travel rewards program. As a member, you can unlock instant savings and member perks when you're logged in. Typically, booking in advance will help you save on your business hotel booking. But, if you're making a last-minute reservation, be sure to check for last-minute deals. ### Can I cancel my business hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right business hotel in Knoxville for you. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [1 Star Hotels in Sharpsburg](https://www.expedia.ca/1Star-Sharpsburg-Hotels.s10-0-d157080.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Adamstown](https://www.expedia.ca/Adamstown-Hotels-Luxury-Hotel.0-0-d6338378-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Adamstown Hotels](https://www.expedia.ca/Adamstown-Hotels.d6338378.Travel-Guide-Hotels) - [B&B in Antietam](https://www.expedia.ca/Antietam-Bed-And-Breakfast.d553248635975871648-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near Antietam Creek](https://www.expedia.ca/Antietam-Creek-Hotels.0-l553248621532662485-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Antietam](https://www.expedia.ca/Antietam-Hotels-Cheap-Hotels.0-0-d553248635975871648-tCheapHotels.Travel-Guide-Filter-Hotels) - 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