Title: Book the Best Knowles Island Plantation SPA Resorts from CA $459 - Spa Hotels in Knowles Island Plantation, Ridgeland | Expedia.ca [Knowles Island Plantation Travel Guide](https://expedia.ca/Ridgeland-Knowles-Island-Plantation.dx553248635976469454)[Vacation Rentals in Ridgeland](https://expedia.ca/Ridgeland-Vacation-Rentals.d151300.Travel-Guide-VacationRentals)[Flights to Ridgeland](https://expedia.ca/Cheap-Flights-To-Ridgeland.d151300.Travel-Guide-Flights)[Knowles Island Plantation Car Rentals](https://expedia.ca/Car-Rentals-In-Knowles-Island-Plantation.d553248635976469454.Car-Rental-Guide)[Knowles Island Plantation Vacations](https://expedia.ca/Knowles-Island-Plantation.d553248635976469454.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Knowles Island Plantation, Ridgeland from CA $459 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Knowles Island Plantation Spa Hotels Tonight [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=553248635976469454&startDate=2025-10-16&endDate=2025-10-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=553248635976469454&startDate=2025-10-17&endDate=2025-10-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976469454&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976469454&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Knowles Island Plantation Spa Hotels ![Balcony](https://images.trvl-media.com/lodging/18000000/17510000/17501300/17501261/0c5358cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/18000000/17510000/17501300/17501261/c0f7cedf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17510000/17501300/17501261/d16b26bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/18000000/17510000/17501300/17501261/fc3d7faf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anchorage 1770 Historic District 9.2/10 Wonderful (216) "Beautifully renovated historic gem in the middle of Beaufort. Great for a romantic getaway. The staff were very Welcoming and assisted with all aspects of our vacation. " CA $418 CA $459 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Beaufort-Hotels-Anchorage-1770.h17501261.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=553248635976469454&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Knowles Island Plantation Hotel Reviews ![Okatie Hilton Head Hotel](//images.trvl-media.com/lodging/1000000/520000/519100/519036/79bfcd2f_y.jpg) ### Okatie Hilton Head Hotel 10/10 Excellent "The staff was extremely helpful when I needed directions to a local nature preserve. The room was equipped with all of the amenities you might need while traveling. Thanks for the free wifi!" [](https://expedia.ca/Hilton-Head-Hotels-Okatie-Hilton-Head-Hotel.h519036.Hotel-Information) ![Hilton Garden Inn Beaufort](//images.trvl-media.com/lodging/2000000/1860000/1853300/1853242/99f46a60_y.jpg) ### Hilton Garden Inn Beaufort 10/10 Excellent "Nice clean room, nice hotel recommend " [](https://expedia.ca/Beaufort-Hotels-Hilton-Garden-Inn-Beaufort.h1853242.Hotel-Information) ![Rhett House Inn](//images.trvl-media.com/lodging/1000000/50000/42900/42874/7a3da7fe_y.jpg) ### Rhett House Inn 10/10 Excellent "For a stay in Beaufort, SC, for my money, the Rhett House Inn cannot be beat. It is located in the heart of the historic district and within walking distance of almost everything. We parked our car on Friday afternoon and didn't see it again until we checked out on Sunday. In between, we walked to various sites of interest and restaurants throughout the day. BTW, a cooked-to-order breakfast, coffee & tea are included, as well as afternoon cheese and evening dessert. The staff is friendly and accommodating. " [](https://expedia.ca/Beaufort-Hotels-Rhett-House-Inn.h42874.Hotel-Information) ![Beaufort Inn](//images.trvl-media.com/lodging/3000000/2170000/2169500/2169413/1b8cc041_y.jpg) ### Beaufort Inn 10/10 Excellent "I wish I had taken pics, this hotel is absolutely gorgeous. Our room was in back in one of the cottages. It was very spacious & had a walk-in shower that was huge. I hope I am able to come back again! " [](https://expedia.ca/Beaufort-Hotels-Beaufort-Inn.h2169413.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Knowles Island Plantation? > Book one of our lush spa hotels and pamper yourself from the moment you arrive. Spa hotels are a great way to break away from your daily routine and add a layer of luxury to your holiday. ### What's there to see and do in Knowles Island Plantation? > Enjoy Knowles Island Plantation with a stop at Marine Corps Recruit Depot Parris Island, Highway 21 Drive-In Theater, and Spanish Moss Trail. If you have extra time while you're in the area, you might want to stop by Beaufort National Cemetery and St. Helena's Episcopal Church. ### What is a Knowles Island Plantation spa hotel? > Spa hotels in Knowles Island Plantation have full on-site spas which offer services including therapies and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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