Title: Book the Best Keowee Plantation SPA Resorts from CA $95 - Spa Hotels in Keowee Plantation, Seneca | Expedia.ca [Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Things to do in Seneca](https://expedia.ca/Things-To-Do-In-Seneca.d6548.Travel-Guide-Activities)[Keowee Plantation Car Rentals](https://expedia.ca/Car-Rentals-In-Keowee-Plantation.d553248635976477960.Car-Rental-Guide)[Keowee Plantation Vacations](https://expedia.ca/Keowee-Plantation.d553248635976477960.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Keowee Plantation, Seneca from CA $95 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Keowee Plantation Spa Hotels Tonight [Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=553248635976477960&startDate=2025-10-10&endDate=2025-10-11&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 11 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976477960&startDate=2025-10-11&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976477960&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976477960&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Keowee Plantation Spa Hotels We don't have any properties that match your exact search [See all properties in Keowee Plantation](https://expedia.ca/Hotel-Search?startDate=2025-10-25&endDate=2025-10-26®ionId=553248635976477960&adults=2) ## Recommended hotels in Keowee Plantation ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/d191b963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/01158bad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson Seneca 9.0/10 Wonderful (1008) "Very beautiful place to stay" CA $153 CA $190 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/441edd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/7cb8ae6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/7bc9a82a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Anderson Anderson 7.6/10 Good (1010) "Rooms were clean and staff was very accommodating!" CA $86 CA $95 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/f93d0c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/452fcf9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/94f8bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/706f626f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson Anderson 8.2/10 Very good (1002) "Great stay" CA $113 CA $126 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/389cca02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/3f88a754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/64115ebf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/4c01aca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG Anderson 9.0/10 Wonderful (570) "Good breakfast, clean " CA $145 CA $161 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/78008f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/3e16f761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/1c4bc101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn @ Clemson Clemson 8.0/10 Very good (1004) "Very nice staff and great place to stay" CA $103 CA $115 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/a42189bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/a75f160d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7b9d65c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast Pendleton 10/10 Exceptional (74) "Beautiful home, very clean, easy self check in. I unfortunately was not able to join breakfast during my stay, but the host gave me a goodie bag to go, which was much appreciated! " CA $174 CA $264 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/aa533fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/282fab11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center Clemson 8.2/10 Very good (1011) "Great value and great hotel. We would stay there again. " CA $136 CA $151 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Reception hall](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/959a330b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/06863ceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/241a5cc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/cb83efe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Patrick Square Clemson 9.8/10 Exceptional (764) "Beautiful hotel and close to restaurants and bars. " CA $209 CA $232 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/78e2a715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/7711c34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/d53ff29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/dfa7a980.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Anderson Anderson 9.0/10 Wonderful (650) "When I got there to check in the front desk worker was very nice and helpful room was nice and clean " CA $131 CA $146 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/cbe6a617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e408dd97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson Clemson 9.6/10 Exceptional (546) "Great place for visiting the university " CA $201 CA $223 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-25&endDate=2025-10-26®ionId=553248635976477960&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Keowee Plantation Hotel Reviews ![Hampton Inn & Suites Seneca-Clemson Area](//images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg) ### Hampton Inn & Suites Seneca-Clemson Area 10/10 Excellent "Staff were friendly and helpful. Room was clean. Parking easy and plentiful. Would definitely go back there if visiting the area again!! Loved the steak, eggs and biscuit breakfast on Sunday morning!!" [](https://expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Keowee Plantation? > Book one of our lush spa hotels and pamper yourself from the moment you arrive. Spa hotels are the perfect way to break away from your daily routine and add a layer of luxury to your vacation. ### What's there to see and do in Keowee Plantation? > Take in the sights and attractions that Keowee Plantation offers with a visit to Lake Keowee, Keowee Reservoir, and Littlejohn Coliseum. If you have extra time while you're in the area, you might want to stop by Memorial Stadium and Walker Golf Course. ### What is a Keowee Plantation spa hotel? > Spa hotels in Keowee Plantation have full on-site spas which offer services such as couples massages and a range of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Aparthotels in Central](https://www.expedia.ca/Central-Apart-Hotels.d10503-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Central](https://www.expedia.ca/Central-Bed-And-Breakfast.d10503-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Starwood Capital Hotels in Central](https://www.expedia.ca/Central-Hotels-Starwood-Capital.0-0-d10503--bStarwoodCapital.Travel-Guide-Filter-Hotels) - [Central Hotels](https://www.expedia.ca/Central-Hotels.d10503.Travel-Guide-Hotels) - [Motels in Central](https://www.expedia.ca/Central-Motels.d10503-aaMotels.Travel-Guide-Accommodation) - [Resorts in Central](https://www.expedia.ca/Central-Resort-Hotels.d10503-aaResortHotels.Travel-Guide-Accommodation) - [Aparthotels in Clemson](https://www.expedia.ca/Clemson-Apart-Hotels.d6594-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Clemson](https://www.expedia.ca/Clemson-Bed-And-Breakfast.d6594-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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